Functional Diversity of Mammalian Small Heat Shock Proteins: A Review

The chaperone-assisted selective autophagy complex dynamics and dysfunctions

(2023) Barbara Tedesco et al.   Autophagy

α-Crystallin Domains of Five Human Small Heat Shock Proteins (sHsps) Differ in Dimer Stabilities and Ability to Incorporate Themselves into Oligomers of Full-Length sHsps

(2023) Vladislav M. Shatov et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Disordered region encodes α-crystallin chaperone activity toward lens client γD-crystallin

(2023) Christopher N. Woods et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heat Shock Protein 27 Is Involved in the Bioactive Glass Induced Osteogenic Response of Human Mesenchymal Stem Cells

(2023) Laura Hyväri et al.   Cells

Hsp22 pretreatment protects against LPS-induced hippocampal injury by alleviating neuroinflammation and apoptosis by regulating the NLRP3/Caspase1/IL-1β signaling pathway in mice

(2023) Shengliang Peng et al.   Aging-US

High HSPB1 expression predicts poor clinical outcomes and correlates with breast cancer metastasis

(2023) Qin Huo et al.   BMC CANCER

CD93 Ameliorates Diabetic Wounds by Promoting Angiogenesis via the p38MAPK/MK2/HSP27 Axis

(2023) Yuan Xu et al.   EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY

The HSPB1-p62/SQSTM1 functional complex regulates the unconventional secretion and transcellular spreading of the HD-associated mutant huntingtin protein

(2023) R Bonavita et al.   HUMAN MOLECULAR GENETICS

FYN/TOPK/HSPB1 axis facilitates the proliferation and metastasis of gastric cancer

(2023) SanFei Peng et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

HSPB7 oppositely regulates human mesenchymal stromal cell-derived osteogenesis and adipogenesis

(2023) Shuang Zhang et al.   Stem Cell Research & Therapy

Mode of Action of Heat Shock Protein (HSP) Inhibitors against Viruses through Host HSP and Virus Interactions

(2023) Shuang Wu et al.   Genes

Molecular Chaperones’ Potential against Defective Proteostasis of Amyotrophic Lateral Sclerosis

(2023) Sumit Kinger et al.   Cells

Mechanistic insights into heat shock protein 27, a potential therapeutic target for cardiovascular diseases

(2023) Yifei Zou et al.   Frontiers in Cardiovascular Medicine

Dynamics and Composition of Small Heat Shock Protein Condensates and Aggregates

(2023) Joep Joosten et al.   JOURNAL OF MOLECULAR BIOLOGY

Promotion of the Differentiation of Dental Pulp Stem Cells into Oligodendrocytes by Knockdown of Heat Shock Protein 27

(2022) Shu-Lin Guo et al.   DEVELOPMENTAL NEUROSCIENCE

Alpha B-Crystallin in Muscle Disease Prevention: The Role of Physical Activity

(2022) Ivan Dimauro et al.   MOLECULES

Oligodendroglia-derived extracellular vesicles activate autophagy via LC3B/BAG3 to protect against oxidative stress with an enhanced effect for HSPB8 enriched vesicles

(2022) Bram Van den Broek et al.   Cell Communication and Signaling

The protective role of HSP27 in ocular diseases

(2022) K Sooraj et al.   MOLECULAR BIOLOGY REPORTS

TAT-HSP27 Peptide Improves Neurologic Deficits via Reducing Apoptosis After Experimental Subarachnoid Hemorrhage

(2022) Xiao-yan Zhou et al.   Frontiers in Cellular Neuroscience

Insights on Human Small Heat Shock Proteins and Their Alterations in Diseases

(2022) B. Tedesco et al.   Frontiers in Molecular Biosciences

The Role of Hsp27 in Chemotherapy Resistance

(2022) Marios Lampros et al.   Biomedicines

Mitochondria ROS and mitophagy in acute kidney injury

(2022) Lianjiu Su et al.   Autophagy

Human HspB1, HspB3, HspB5 and HspB8: Shaping these disease factors during vertebrate evolution

(2022) Rainer Benndorf et al.   CELL STRESS & CHAPERONES

The Small Heat Shock Protein, HSPB1, Interacts with and Modulates the Physical Structure of Membranes

(2022) Balint Csoboz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CircRNA-ST6GALNAC6 increases the sensitivity of bladder cancer cells to erastin-induced ferroptosis by regulating the HSPB1/P38 axis

(2022) Li Wang et al.   LABORATORY INVESTIGATION

BAG3 Alleviates Atherosclerosis by Inhibiting Endothelial-to-Mesenchymal Transition via Autophagy Activation

(2022) Hongtao Diao et al.   Genes

Phosphoserine-86-HSPB1 (pS86-HSPB1) is cytoplasmic and highly induced in rat myometrium at labour

(2022) E. I. Miskiewicz et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Development of the Connecting Piece in ODF1-Deficient Mouse Spermatids

(2022) Sigrid Hoyer-Fender   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Polo-Like Kinase 2 Plays an Essential Role in Cytoprotection against MG132-Induced Proteasome Inhibition via Phosphorylation of Serine 19 in HSPB5

(2022) Shuji Ueda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

HSPB1 overexpression improves hypoxic-ischemic brain damage by attenuating ferroptosis in rats through promoting G6PD expression

(2022) Yi Dai et al.   JOURNAL OF NEUROPHYSIOLOGY

Phosphorylation of the small heat shock protein HspB1 regulates cytoskeletal recruitment and cell motility

(2022) Laura M. Hoffman et al.   MOLECULAR BIOLOGY OF THE CELL

Heat shock proteins and viral infection

(2022) Xizhen Zhang et al.   Frontiers in Immunology

A Charcot-Marie-Tooth-Causing Mutation in HSPB1 Decreases Cell Adaptation to Repeated Stress by Disrupting Autophagic Clearance of Misfolded Proteins

(2022) Xuelian Zhang et al.   Cells

HSPB1 Regulates Autophagy and Apoptosis in Vascular Smooth Muscle Cells in Arteriosclerosis Obliterans

(2022) Keqin Chen et al.   Cardiovascular Therapeutics

Silica Nanoparticles Trigger Chaperone HSPB8‐Assisted Selective Autophagy via TFEB Activation in Hepatocytes

(2022) Ye Zhu et al.   Small

Tat-hspb1 Suppresses Clear Cell Renal Cell Carcinoma (ccRCC) Growth via Lysosomal Membrane Permeabilization

(2022) Lin Zhang et al.   Cancers

Ferroptosis: mechanisms, biology and role in disease

(2021) Xuejun Jiang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

O-GlcNAc modification of small heat shock proteins enhances their anti-amyloid chaperone activity

(2021) Aaron T. Balana et al.   Nature Chemistry

Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptor

(2021) Tatiana Tiago et al.   Cell Death & Disease

Heat shock protein 22 modulates NRF1/TFAM-dependent mitochondrial biogenesis and DRP1-sparked mitochondrial apoptosis through AMPK-PGC1α signaling pathway to alleviate the early brain injury of subarachnoid hemorrhage in rats

(2021) Haiyan Fan et al.   Redox Biology

ATG9A regulates proteostasis through reticulophagy receptors FAM134B and SEC62 and folding chaperones CALR and HSPB1

(2021) Brendan K. Sheehan et al.   iScience

The chaperone HSPB1 prepares protein aggregates for resolubilization by HSP70

(2021) Conrado C. Gonçalves et al.   Scientific Reports

HspB4/αA-Crystallin Modulates Neuroinflammation in the Retina via the Stress-Specific Inflammatory Pathways

(2021) Madhu Nath et al.   Journal of Clinical Medicine

HspB1 Overexpression Improves Life Span and Stress Resistance in an Invertebrate Model

(2021) Courtney Carroll Alexander et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Hsp22 ameliorates lipopolysaccharide-induced myocardial injury by inhibiting inflammation, oxidative stress, and apoptosis

(2021) Yun Yu et al.   Bioengineered

Esophageal Cancer Stem-like Cells Resist Ferroptosis-Induced Cell Death by Active Hsp27-GPX4 Pathway

(2021) Chen-Chi Liu et al.   Biomolecules

Release of a disordered domain enhances HspB1 chaperone activity toward tau

(2020) Hannah E. R. Baughman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Site‐specific rapid deamidation and isomerization in human lens αA‐crystallin in vitro

(2020) Takumi Takata et al.   PROTEIN SCIENCE

Expression of human HSP27 in yeast extends replicative lifespan and uncovers a hormetic response

(2020) Vittoria de Lima Camandona et al.   BIOGERONTOLOGY

Mutations in HspB1 and hereditary neuropathies

(2020) Lydia K. Muranova et al.   CELL STRESS & CHAPERONES

Small heat shock proteins in neurodegenerative diseases

(2020) Leen Vendredy et al.   CELL STRESS & CHAPERONES

Phosphorylation of the Chaperone-Like HspB5 Rescues Trafficking and Function of F508del-CFTR

(2020) Fanny Degrugillier et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Proteinaceous Transformers: Structural and Functional Variability of Human sHsps

(2020) Mareike Riedl et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of Heat Shock Protein 27 in Modulating Atherosclerotic Inflammation

(2020) Jose A. Inia et al.   Journal of Cardiovascular Translational Research

Mitophagy, Mitochondrial Homeostasis, and Cell Fate

(2020) Kaili Ma et al.   Frontiers in Cell and Developmental Biology

HSPB5 (αB-crystallin) confers protection against paraquat-induced oxidative stress at the organismal level in a tissue-dependent manner

(2020) Prashanth Budnar et al.   CELL STRESS & CHAPERONES

Small Heat Shock Proteins in Cancers: Functions and Therapeutic Potential for Cancer Therapy

(2020) Jixian Xiong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Apoptosis, autophagy and atherosclerosis: relationships and the role of Hsp27

(2020) Ruiting Shan et al.   PHARMACOLOGICAL RESEARCH

Molecular characteristics associated with ferroptosis in hepatocellular carcinoma progression

(2020) Zuo Fei et al.   Human Cell

HSPB7 regulates osteogenic differentiation of human adipose derived stem cells via ERK signaling pathway

(2020) Chanyuan Jin et al.   Stem Cell Research & Therapy

Structure, gene expression, and putative functions of crustacean heat shock proteins in innate immunity

(2020) Wisarut Junprung et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

HSP22 suppresses diabetes-induced endothelial injury by inhibiting mitochondrial reactive oxygen species formation

(2019) Lingling Yu et al.   Redox Biology

Local unfolding of the HSP27 monomer regulates chaperone activity

(2019) T. Reid Alderson et al.   Nature Communications

Mechanisms of Small Heat Shock Proteins

(2019) Maria K. Janowska et al.   Cold Spring Harbor Perspectives in Biology

The effects of HSP27 against UVB-induced photoaging in rat skin

(2019) Yiyi Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies

(2019) Mansour Haidar et al.   Autophagy

Heat shock protein B1 is a key mediator of prolactin-induced beta-cell cytoprotection against oxidative stress

(2019) Letícia F. Terra et al.   FREE RADICAL BIOLOGY AND MEDICINE

HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C

(2019) Miranda P. Collier et al.   Science Advances

The Cytoskeleton—A Complex Interacting Meshwork

(2019) Hohmann et al.   Cells

The small heat shock proteins, HSPB1 and HSPB5, interact differently with lipid membranes

(2019) Antonio De Maio et al.   CELL STRESS & CHAPERONES

Effect of heat-shock protein B7 on oxidative stress in adipocytes from preruminant calves

(2019) Xudong Sun et al.   JOURNAL OF DAIRY SCIENCE

Small Heat Shock Proteins and Human Neurodegenerative Diseases

(2019) L. K. Muranova et al.   BIOCHEMISTRY-MOSCOW

Physiological functions of heat shock proteins

(2019) Qiang Shan et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Regulation of small heat shock proteins by hetero-oligomer formation

(2019) Evgeny V. Mymrikov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unconventional secretion of α-Crystallin B requires the Autophagic pathway and is controlled by phosphorylation of its serine 59 residue

(2019) M. D’Agostino et al.   Scientific Reports

Interference of Hsp27 Results in Apoptosis Induced by Photodamage via Regulation of Subcellular Localization of p21 in Immortalized Human Keratinocytes

(2019) Chuan Liu et al.   MEDICAL SCIENCE MONITOR

Regulation of BECN1-mediated autophagy by HSPB6: Insights from a human HSPB6S10F mutant

(2018) Guan-Sheng Liu et al.   Autophagy

Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1

(2018) Peng Sun et al.   Autophagy

Mechanisms and functions of cellular senescence

(2018) Nicolás Herranz et al.   JOURNAL OF CLINICAL INVESTIGATION

Orchestrated control of filaggrin–actin scaffolds underpins cornification

(2018) Danuta Gutowska-Owsiak et al.   Cell Death & Disease

P2RX7-MAPK1/2-SP1 axis inhibits MTOR independent HSPB1-mediated astroglial autophagy

(2018) Ji-Eun Kim et al.   Cell Death & Disease

Ac2-26 Induces IKKβ Degradation Through Chaperone-Mediated Autophagy Via HSPB1 in NCM-Treated Microglia

(2018) Lu Liu et al.   Frontiers in Molecular Neuroscience

Overexpressed HspB6 Underlines a Novel Inhibitory Role in Kainic Acid-Induced Epileptic Seizure in Rats by Activating the cAMP-PKA Pathway

(2018) Ai-Qin Qi et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

The role of heat shock protein 27 phosphorylation in the proliferation and apoptosis of human umbilical vein endothelial cells induced by Visfatin

(2018) Haifeng Chen et al.   MICROVASCULAR RESEARCH

HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons

(2017) Xiao-Cheng Li et al.   International Journal of Medical Sciences

Protective effect of HSP27 in atherosclerosis and coronary heart disease by inhibiting reactive oxygen species

(2017) Hongli Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

BAG3 plays a central role in proteostasis in the heart

(2017) Wataru Mizushima et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanical signals activate p38 MAPK pathway-dependent reinforcement of actin via mechanosensitive HspB1

(2017) Laura Hoffman et al.   MOLECULAR BIOLOGY OF THE CELL

HSPB7 is indispensable for heart development by modulating actin filament assembly

(2017) Tongbin Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis

(2017) Donna Kennedy et al.   Cell Death & Disease

Tat-HSP22 inhibits oxidative stress-induced hippocampal neuronal cell death by regulation of the mitochondrial pathway

(2017) Hyo Sang Jo et al.   Molecular Brain

HSPB7 prevents cardiac conduction system defect through maintaining intercalated disc integrity

(2017) Wern-Chir Liao et al.   PLoS Genetics

Translocation of molecular chaperones to the titin springs is common in skeletal myopathy patients and affects sarcomere function

(2017) Andreas Unger et al.   Acta Neuropathologica Communications

Hsp20-Mediated Activation of Exosome Biogenesis in Cardiomyocytes Improves Cardiac Function and Angiogenesis in Diabetic Mice

(2016) Xiaohong Wang et al.   DIABETES

The function of small heat-shock proteins and their implication in proteostasis

(2016) A. Strauch et al.   Essays in Biochemistry

The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins

(2016) Evgeny V. Mymrikov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quercetin blocks t-AUCB-induced autophagy by Hsp27 and Atg7 inhibition in glioblastoma cells in vitro

(2016) Junyang Li et al.   JOURNAL OF NEURO-ONCOLOGY

Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular protection and efficient refolding

(2016) Sophia Ungelenk et al.   Nature Communications

HSP27 Inhibits Homocysteine-Induced Endothelial Apoptosis by Modulation of ROS Production and Mitochondrial Caspase-Dependent Apoptotic Pathway

(2016) Xin Tian et al.   Biomed Research International

Extracellular Release and Signaling by Heat Shock Protein 27: Role in Modifying Vascular Inflammation

(2016) Zarah Batulan et al.   Frontiers in Immunology

HSPB1 Enhances SIRT2-Mediated G6PD Activation and Promotes Glioma Cell Proliferation

(2016) Hongxing Ye et al.   PLoS One

Small Heat Shock Proteins and Distal Hereditary Neuropathies

(2015) V. V. Nefedova et al.   BIOCHEMISTRY-MOSCOW

Small heat shock proteins: Role in cellular functions and pathology

(2015) Raman Bakthisaran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Quaternary structure of human small heat shock protein HSPB6 (Hsp20) in crowded media modeled by trimethylamine N-oxide (TMAO): Effect of protein phosphorylation

(2015) Nikolai N. Sluchanko et al.   BIOCHIMIE

Extracellular α-crystallin protects astrocytes from cell death through activation of MAPK, PI3K/Akt signaling pathway and blockade of ROS release from mitochondria

(2015) Zhihui Zhu et al.   BRAIN RESEARCH

Palytoxin Induces Dissociation of HSP 27 Oligomers through a p38 Protein Kinase Pathway

(2015) Chiara Berni et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Structure of the α-crystallin domain from the redox-sensitive chaperone, HSPB1

(2015) Ponni Rajagopal et al.   JOURNAL OF BIOMOLECULAR NMR

Intracellular transduction of TAT-Hsp27 fusion protein enhancing cell survival and regeneration capacity of cardiac stem cells in acute myocardial infarction

(2015) Hye Jung Kim et al.   JOURNAL OF CONTROLLED RELEASE

A First Line of Stress Defense: Small Heat Shock Proteins and Their Function in Protein Homeostasis

(2015) Martin Haslbeck et al.   JOURNAL OF MOLECULAR BIOLOGY

R-Ras Inhibits VEGF-Induced p38MAPK Activation and HSP27 Phosphorylation in Endothelial Cells

(2015) Junko Sawada et al.   JOURNAL OF VASCULAR RESEARCH

Dual Functions in Response to Heat Stress and Spermatogenesis: Characterization of Expression Profile of Small Heat Shock Proteins 9 and 10 in Goat Testis

(2015) Wenjuan Xun et al.   Biomed Research International

Small Heat Shock Protein Beta-1 (HSPB1) Is Upregulated and Regulates Autophagy and Apoptosis of Renal Tubular Cells in Acute Kidney Injury

(2015) Tatsuki Matsumoto et al.   PLoS One

Characterization of Mutants of Human Small Heat Shock Protein HspB1 Carrying Replacements in the N-Terminal Domain and Associated with Hereditary Motor Neuron Diseases

(2015) Lydia K. Muranova et al.   PLoS One

Phosphorylation of heat shock protein 27 antagonizes TNF-α induced HeLa cell apoptosis via regulating TAK1 ubiquitination and activation of p38 and ERK signaling

(2014) Zhilin Qi et al.   CELLULAR SIGNALLING

Human myocytes are protected from titin aggregation-induced stiffening by small heat shock proteins

(2014) Sebastian Kötter et al.   JOURNAL OF CELL BIOLOGY

Decreased Expression of Heat Shock Protein 20 in Colorectal Cancer and Its Implication in Tumorigenesis

(2014) Young-Tae Ju et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Phosphorylation of AKT induced by phosphorylated Hsp27 confers the apoptosis-resistance in t-AUCB-treated glioblastoma cells in vitro

(2014) Rujun Li et al.   JOURNAL OF NEURO-ONCOLOGY

Molecular structure and dynamics of the dimeric human small heat shock protein HSPB6

(2014) Stephen D. Weeks et al.   JOURNAL OF STRUCTURAL BIOLOGY

Elevated expression of CRYAB predicts unfavorable prognosis in non-small cell lung cancer

(2014) Hui Qin et al.   MEDICAL ONCOLOGY

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(2014) Chunhua Jin et al.   MOLECULAR MEDICINE

Neuropathy- and myopathy-associated mutations in human small heat shock proteins: Characteristics and evolutionary history of the mutation sites

(2014) Rainer Benndorf et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Haplo-deficiency of ODF1/HSPB10 in mouse sperm causes relaxation of head-to-tail linkage

(2014) Kefei Yang et al.   REPRODUCTION

HSP27 phosphorylation modulates TRAIL-induced activation of Src-Akt/ERK signaling through interaction with β-arrestin2

(2013) Shimei Qi et al.   CELLULAR SIGNALLING

Cellular Mechanotransduction Relies on Tension-Induced and Chaperone-Assisted Autophagy

(2013) Anna Ulbricht et al.   CURRENT BIOLOGY

Extracellular HSP27 mediates angiogenesis through Toll-like receptor 3

(2013) Dominique Thuringer et al.   FASEB JOURNAL

Human small heat shock proteins: Protein interactomes of homo- and hetero-oligomeric complexes: An update

(2013) André-Patrick Arrigo   FEBS LETTERS

The   Crystallin Domain of Small Heat Shock Protein b8 (Hspb8) Acts as Survival and Differentiation Factor in Adult Hippocampal Neurogenesis

(2013) G. Ramirez-Rodriguez et al.   JOURNAL OF NEUROSCIENCE

HSPB1 Facilitates the Formation of Non-Centrosomal Microtubules

(2013) Leonardo Almeida-Souza et al.   PLoS One

Soluble HSPB1 regulates VEGF-mediated angiogenesis through their direct interaction

(2012) Yoon-Jin Lee et al.   ANGIOGENESIS

Cofilin weakly interacts with 14-3-3 and therefore can only indirectly participate in regulation of cell motility by small heat shock protein HspB6 (Hsp20)

(2012) Maria V. Sudnitsyna et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Monomeric 14-3-3ζ Has a Chaperone-Like Activity and Is Stabilized by Phosphorylated HspB6

(2012) Nikolai N. Sluchanko et al.   BIOCHEMISTRY

Extracellular HSP27 acts as a signaling molecule to activate NF-κB in macrophages

(2012) Samira Salari et al.   CELL STRESS & CHAPERONES

sHSP in the eye lens: Crystallin mutations, cataract and proteostasis

(2012) Alice R. Clark et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Small heat shock proteins in redox metabolism: Implications for cardiovascular diseases

(2012) Elisabeth S. Christians et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Small heat shock proteins and the cytoskeleton: An essential interplay for cell integrity?

(2012) G. Wettstein et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Phosphorylation of HSP27 by Protein Kinase D Is Essential for Mediating Neuroprotection against Ischemic Neuronal Injury

(2012) R. A. Stetler et al.   JOURNAL OF NEUROSCIENCE

Cotargeting Stress-Activated Hsp27 and Autophagy as a Combinatorial Strategy to Amplify Endoplasmic Reticular Stress in Prostate Cancer

(2012) M. Kumano et al.   MOLECULAR CANCER THERAPEUTICS

SIRT2 interferes with autophagy-mediated degradation of protein aggregates in neuronal cells under proteasome inhibition

(2012) Jiyeong Gal et al.   NEUROCHEMISTRY INTERNATIONAL

Hsp20 Functions as a Novel Cardiokine in Promoting Angiogenesis via Activation of VEGFR2

(2012) Xiaowei Zhang et al.   PLoS One

Heat shock protein 27 and p16 immunohistochemistry in cervical intraepithelial neoplasia and squamous cell carcinoma

(2012) Akiko Tozawa-Ono et al.   Human Cell

Metabolic regulation by HMGB1-mediated autophagy and mitophagy

(2011) Rui Kang et al.   Autophagy

Acetylation of Heat Shock Protein 20 (Hsp20) Regulates Human Myometrial Activity

(2011) Magdalena Karolczak-Bayatti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Titin visualization in real time reveals an unexpected level of mobility within and between sarcomeres

(2011) Katharina da Silva Lopes et al.   JOURNAL OF CELL BIOLOGY

HspB8 mutation causing hereditary distal motor neuropathy impairs lysosomal delivery of autophagosomes

(2011) Alice S. Kwok et al.   JOURNAL OF NEUROCHEMISTRY

Phosphorylation of human small heat shock protein HspB8 (Hsp22) by ERK1 protein kinase

(2011) Anton A. Shemetov et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The Small Heat Shock Protein ODF1/HSPB10 Is Essential for Tight Linkage of Sperm Head to Tail and Male Fertility in Mice

(2011) K. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

The small heat shock protein HspB2 is a novel anti-apoptotic protein that inhibits apical caspase activation in the extrinsic apoptotic pathway

(2010) Shayna E. Oshita et al.   BREAST CANCER RESEARCH AND TREATMENT

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

HSPB7 is the most potent polyQ aggregation suppressor within the HSPB family of molecular chaperones

(2010) Michel J. Vos et al.   HUMAN MOLECULAR GENETICS

Selective degradation of aggregate-prone CryAB mutants by HSPB1 is mediated by ubiquitin–proteasome pathways

(2010) Huali Zhang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Autophagy: cellular and molecular mechanisms

(2010) Danielle Glick et al.   JOURNAL OF PATHOLOGY

The Giant Protein Titin as an Integrator of Myocyte Signaling Pathways

(2010) Wolfgang A. Linke et al.   PHYSIOLOGY

The anti-apoptotic function of human αA-crystallin is directly related to its chaperone activity

(2010) N Pasupuleti et al.   Cell Death & Disease

 B-crystallin regulation of angiogenesis by modulation of VEGF

(2009) S. Kase et al.   BLOOD

Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology

(2009) Sergiy Kostenko et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Blockade of Hsp20 Phosphorylation Exacerbates Cardiac Ischemia/Reperfusion Injury by Suppressed Autophagy and Increased Cell Death

(2009) Jiang Qian et al.   CIRCULATION RESEARCH

Heat shock protein 27 is over-expressed in tumor tissues and increased in sera of patients with gastric adenocarcinoma

(2009) Qiaojia Huang et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

The Small Heat-Shock Protein Hsp27 Undergoes ERK-Dependent Phosphorylation and Redistribution to the Cytoskeleton in Response to Dual Leucine Zipper-Bearing Kinase Expression

(2009) Hubert Robitaille et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Treatment with transducible phosphopeptide analogues of the small heat shock–related protein, HSP20, after experimental subarachnoid hemorrhage: prevention and reversal of delayed decreases in cerebral perfusion

(2009) Elizabeth J. Furnish et al.   JOURNAL OF NEUROSURGERY

Mechanisms of regulated unconventional protein secretion

(2009) Walter Nickel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitogen Activated Protein Kinase Activated Protein Kinase 2 Regulates Actin Polymerization and Vascular Leak in Ventilator Associated Lung Injury

(2009) Mahendra Damarla et al.   PLoS One

Hsp27 Inhibits Bax Activation and Apoptosis via a Phosphatidylinositol 3-Kinase-dependent Mechanism

(2008) Andrea Havasi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell Permeant Peptide Analogues of the Small Heat Shock Protein, HSP20, Reduce TGF-β1-Induced CTGF Expression in Keloid Fibroblasts

(2008) Luciana B. Lopes et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Autophagic cell death: the story of a misnomer

(2008) Guido Kroemer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Caspases in apoptosis and beyond

(2008) J Li et al.   ONCOGENE

Bcl2L12-mediated inhibition of effector caspase-3 and caspase-7 via distinct mechanisms in glioblastoma

(2008) A. H. Stegh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of heat shock protein 27 in extravillous trophoblast differentiation

(2007) S. Tartakover Matalon et al.   JOURNAL OF CELLULAR BIOCHEMISTRY