Phosphorylation of the small heat shock protein HspB1 regulates cytoskeletal recruitment and cell motility

LIM domain proteins in cell mechanobiology

(2021) Caitlin A. Anderson et al.   Cytoskeleton

Stress fiber strain recognition by the LIM protein testin is cryptic and mediated by RhoA

(2021) Stefano Sala et al.   MOLECULAR BIOLOGY OF THE CELL

Small heat-shock proteins and their role in mechanical stress

(2020) Miranda P. Collier et al.   CELL STRESS & CHAPERONES

Small heat shock proteins in neurodegenerative diseases

(2020) Leen Vendredy et al.   CELL STRESS & CHAPERONES

Sex differences in COVID-19 mortality: opportunity to develop HSP27 (HSPB1) immunotherapy to treat hyper-inflammation?

(2020) Edward R. O’Brien et al.   CELL STRESS & CHAPERONES

Mechanical stress triggers nuclear remodeling and the formation of transmembrane actin nuclear lines with associated nuclear pore complexes

(2020) Laura M. Hoffman et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanosensing through Direct Binding of Tensed F-Actin by LIM Domains

(2020) Xiaoyu Sun et al.   DEVELOPMENTAL CELL

Evolutionarily diverse LIM domain-containing proteins bind stressed actin filaments through a conserved mechanism

(2020) Jonathan D. Winkelman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C

(2019) Miranda P. Collier et al.   Science Advances

Combination of Anti-Cancer Drugs with Molecular Chaperone Inhibitors

(2019) Maxim Shevtsov et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Migration regulates cellular mechanical states

(2019) Stephanie S. Chang et al.   MOLECULAR BIOLOGY OF THE CELL

Apatorsen plus docetaxel versus docetaxel alone in platinum-resistant metastatic urothelial carcinoma (Borealis-2)

(2018) Jonathan E. Rosenberg et al.   BRITISH JOURNAL OF CANCER

Heat shock protein 27 (HSPB1) suppresses the PDGF-BB-induced migration of osteoblasts

(2017) Shingo Kainuma et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Mechanical signals activate p38 MAPK pathway-dependent reinforcement of actin via mechanosensitive HspB1

(2017) Laura Hoffman et al.   MOLECULAR BIOLOGY OF THE CELL

Heat Shock Proteins Promote Cancer: It's a Protection Racket

(2016) Stuart K. Calderwood et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mechanobiology

(2015) G. V. Shivashankar et al.   Integrative Biology

Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly

(2015) Edward R. Horton et al.   NATURE CELL BIOLOGY

Forcing cells into shape: the mechanics of actomyosin contractility

(2015) Michael Murrell et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanical strain induces E-cadherin-dependent Yap1 and  -catenin activation to drive cell cycle entry

(2015) B. W. Benham-Pyle et al.   SCIENCE

Geometry Regulates Traction Stresses in Adherent Cells

(2014) Patrick W. Oakes et al.   BIOPHYSICAL JOURNAL

YAP/TAZ as mechanosensors and mechanotransducers in regulating organ size and tumor growth

(2014) Boon Chuan Low et al.   FEBS LETTERS

A new link between the retrograde actin flow and focal adhesions

(2014) Sawako Yamashiro et al.   JOURNAL OF BIOCHEMISTRY

Forces in Tissue Morphogenesis and Patterning

(2013) Carl-Philipp Heisenberg et al.   CELL

Vinculin–actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth

(2013) Ingo Thievessen et al.   JOURNAL OF CELL BIOLOGY

LIM Domains Target Actin Regulators Paxillin and Zyxin to Sites of Stress Fiber Strain

(2013) Mark A. Smith et al.   PLoS One

Cell Stress Promotes the Association of Phosphorylated HspB1 with F-Actin

(2013) Joseph P. Clarke et al.   PLoS One

Heat Shock Protein B1-Deficient Mice Display Impaired Wound Healing

(2013) Jonathan Crowe et al.   PLoS One

Continuum Mixture Models of Biological Growth and Remodeling: Past Successes and Future Opportunities

(2012) G.A. Ateshian et al.   Annual Review of Biomedical Engineering

Actin Filaments as Tension Sensors

(2012) Vitold E. Galkin et al.   CURRENT BIOLOGY

Small heat shock proteins in cancer therapy and prognosis

(2012) Amina Zoubeidi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

HSPBs: Small proteins with big implications in human disease

(2012) Harm H. Kampinga et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Small heat shock proteins and the cytoskeleton: An essential interplay for cell integrity?

(2012) G. Wettstein et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators

(2012) Laura M. Hoffman et al.   MOLECULAR BIOLOGY OF THE CELL

Transduction of mechanical and cytoskeletal cues by YAP and TAZ

(2012) Georg Halder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Quantitative proteomics of the integrin adhesome show a myosin II-dependent recruitment of LIM domain proteins

(2011) Herbert B Schiller et al.   EMBO REPORTS

Actin filaments function as a tension sensor by tension-dependent binding of cofilin to the filament

(2011) Kimihide Hayakawa et al.   JOURNAL OF CELL BIOLOGY

Dynamic and structural signatures of lamellar actomyosin force generation

(2011) Yvonne Aratyn-Schaus et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A

(2011) A. J. Ehrlicher et al.   NATURE

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

(2011) Jean-Cheng Kuo et al.   NATURE CELL BIOLOGY

Stretching Actin Filaments within Cells Enhances their Affinity for the Myosin II Motor Domain

(2011) Taro Q. P. Uyeda et al.   PLoS One

TAN lines

(2011) G.W. Gant Luxton et al.   Nucleus

A Zyxin-Mediated Mechanism for Actin Stress Fiber Maintenance and Repair

(2010) Mark A. Smith et al.   DEVELOPMENTAL CELL

Force transmission in migrating cells

(2010) Maxime F. Fournier et al.   JOURNAL OF CELL BIOLOGY

Mechanical Distortion of Single Actin Filaments Induced by External Force: Detection by Fluorescence Imaging

(2009) Togo Shimozawa et al.   BIOPHYSICAL JOURNAL

Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology

(2009) Sergiy Kostenko et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mitogen Activated Protein Kinase Activated Protein Kinase 2 Regulates Actin Polymerization and Vascular Leak in Ventilator Associated Lung Injury

(2009) Mahendra Damarla et al.   PLoS One

Stretching Single Talin Rod Molecules Activates Vinculin Binding

(2009) A. del Rio et al.   SCIENCE

Growth Factors, Matrices, and Forces Combine and Control Stem Cells

(2009) D. E. Discher et al.   SCIENCE

Cyclic Strain–Induced HSP27 Phosphorylation Modulates Actin Filaments in Airway Smooth Muscle Cells

(2008) Subhendu Chaudhuri et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

HSP27 regulates cell adhesion and invasion via modulation of focal adhesion kinase and MMP-2 expression

(2008) Joong-Won Lee et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Mechanical forces facilitate actin polymerization at focal adhesions in a zyxin-dependent manner

(2008) H. Hirata et al.   JOURNAL OF CELL SCIENCE

Mechanotransduction - a field pulling together?

(2008) C. S. Chen   JOURNAL OF CELL SCIENCE

Mechanisms of actin stress fibre assembly

(2008) P. NAUMANEN et al.   JOURNAL OF MICROSCOPY

Retrograde Flow and Myosin II Activity within the Leading Cell Edge Deliver F-Actin to the Lamella to Seed the Formation of Graded Polarity Actomyosin II Filament Bundles in Migrating Fibroblasts

(2008) Tom W. Anderson et al.   MOLECULAR BIOLOGY OF THE CELL

Talin depletion reveals independence of initial cell spreading from integrin activation and traction

(2008) Xian Zhang et al.   NATURE CELL BIOLOGY

Mechanotransduction in development: a growing role for contractility

(2008) Michele A. Wozniak et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Small heat shock proteins in smooth muscle

(2008) Sonemany Salinthone et al.   PHARMACOLOGY & THERAPEUTICS

Regulation of contractility by Hsp27 and Hic-5 in rat mesenteric small arteries

(2007) R. Srinivasan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY