HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis

The deubiquitinase Usp27x stabilizes the BH3‐only protein Bim and enhances apoptosis

(2016) Arnim Weber et al.   EMBO REPORTS

The deadly landscape of pro-apoptotic BCL-2 proteins in the outer mitochondrial membrane

(2016) Mark P.A. Luna-Vargas et al.   FEBS Journal

Regulation of Bim in Health and Disease

(2015) Ronit Vogt Sionov et al.   Oncotarget

Regulation of apoptosis by heat shock proteins

(2014) Donna Kennedy et al.   IUBMB LIFE

The Functional Landscape of Hsp27 Reveals New Cellular Processes such as DNA Repair and Alternative Splicing and Proposes Novel Anticancer Targets

(2014) Maria Katsogiannou et al.   MOLECULAR & CELLULAR PROTEOMICS

Hsp27 binding to the 3′UTR of bim mRNA prevents neuronal death during oxidative stress–induced injury: a novel cytoprotective mechanism

(2014) David Dávila et al.   MOLECULAR BIOLOGY OF THE CELL

The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity

(2014) J A Wali et al.   Cell Death & Disease

Heat shock preconditioning protects against ER stress-induced apoptosis through the regulation of the BH3-only protein BIM

(2014) Donna Kennedy et al.   FEBS Open Bio

Protein interactomes of three stress inducible small heat shock proteins: HspB1, HspB5 and HspB8

(2013) André-Patrick Arrigo et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Hsp27 and F-Box Protein  -TrCP Promote Degradation of mRNA Decay Factor AUF1

(2013) M.-L. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress

(2012) Shane Deegan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Small heat shock proteins target mutant cystic fibrosis transmembrane conductance regulator for degradation via a small ubiquitin-like modifier–dependent pathway

(2012) Annette Ahner et al.   MOLECULAR BIOLOGY OF THE CELL

Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis

(2012) S Gupta et al.   Cell Death & Disease

BIMEL, an intrinsically disordered protein, is degraded by 20S proteasomes in the absence of poly-ubiquitylation

(2011) C. M. Wiggins et al.   JOURNAL OF CELL SCIENCE

Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders

(2011) Karen M. Doyle et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Chaperone Hsp27 Modulates AUF1 Proteolysis and AU-Rich Element-Mediated mRNA Degradation

(2011) A. M. Knapinska et al.   MOLECULAR AND CELLULAR BIOLOGY

Alteration of protein folding and degradation in motor neuron diseases: Implications and protective functions of small heat shock proteins

(2011) Serena Carra et al.   PROGRESS IN NEUROBIOLOGY

HSP27 controls GATA-1 protein level during erythroid cell differentiation

(2010) A. de Thonel et al.   BLOOD

Increased Monomerization of Mutant HSPB1 Leads to Protein Hyperactivity in Charcot-Marie-Tooth Neuropathy

(2010) Leonardo Almeida-Souza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hsp27 Protects Adenocarcinoma Cells from UV-Induced Apoptosis by Akt and p21-Dependent Pathways of Survival

(2010) Ragu Kanagasabai et al.   MOLECULAR CANCER RESEARCH

Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E

(2010) C Andrieu et al.   ONCOGENE

HSP72 Protects Cells from ER Stress-induced Apoptosis via Enhancement of IRE1α-XBP1 Signaling through a Physical Interaction

(2010) Sanjeev Gupta et al.   PLOS BIOLOGY

Sustained activation of ERK1/2 by NGF induces microRNA-221 and 222 in PC12 cells

(2009) Kazuya Terasawa et al.   FEBS Journal

Endoplasmic reticulum stress in disorders of myelinating cells

(2009) Wensheng Lin et al.   NATURE NEUROSCIENCE

Hsp27 Inhibits Bax Activation and Apoptosis via a Phosphatidylinositol 3-Kinase-dependent Mechanism

(2008) Andrea Havasi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nerve growth factor blocks thapsigargin-induced apoptosis at the level of the mitochondrionviaregulation of Bim

(2008) E. Szegezdi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Multisite Phosphorylation Regulates Bim Stability and Apoptotic Activity

(2008) Anette Hübner et al.   MOLECULAR CELL

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

(2008) Changchun Xiao et al.   NATURE IMMUNOLOGY

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

(2008) Jerry E. Chipuk et al.   TRENDS IN CELL BIOLOGY