The Giant Protein Titin as an Integrator of Myocyte Signaling Pathways

Exploring the Conformation-Regulated Function of Titin Kinase by Mechanical Pump and Probe Experiments with Single Molecules

(2010) Elias M. Puchner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Common MLP (Muscle LIM Protein) Variant Is Associated With Cardiomyopathy

(2010) Ralph Knöll et al.   CIRCULATION RESEARCH

Insulin signaling regulates cardiac titin properties in heart development and diabetic cardiomyopathy

(2010) Martina Krüger et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Tuning Passive Mechanics through Differential Splicing of Titin during Skeletal Muscle Development

(2009) Coen A.C. Ottenheijm et al.   BIOPHYSICAL JOURNAL

Modulation of Titin-Based Stiffness by Disulfide Bonding in the Cardiac Titin N2-B Unique Sequence

(2009) Anika Grützner et al.   BIOPHYSICAL JOURNAL

Truncation of Titin’s Elastic PEVK Region Leads to Cardiomyopathy With Diastolic Dysfunction

(2009) Henk L. Granzier et al.   CIRCULATION RESEARCH

PKC Phosphorylation of Titin’s PEVK Element

(2009) Carlos Hidalgo et al.   CIRCULATION RESEARCH

Hypophosphorylation of the Stiff N2B Titin Isoform Raises Cardiomyocyte Resting Tension in Failing Human Myocardium

(2009) Attila Borbély et al.   CIRCULATION RESEARCH

Titin isoform expression in aortic stenosis

(2009) Lynne WILLIAMS et al.   CLINICAL SCIENCE

Hsp27 associates with the titin filament system in heat-shocked zebrafish cardiomyocytes

(2009) Nathan R. Tucker et al.   EXPERIMENTAL CELL RESEARCH

Thin filament length dysregulation contributes to muscle weakness in nemaline myopathy patients with nebulin deficiency

(2009) C. A.C. Ottenheijm et al.   HUMAN MOLECULAR GENETICS

Single Molecule Force Spectroscopy of the Cardiac Titin N2B Element

(2009) Yi Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Titin-based mechanical signalling in normal and failing myocardium

(2009) Martina Krüger et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Stressing the giant: A new approach to understanding dilated cardiomyopathy

(2009) Marion Lewis Greaser   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Myocyte remodeling in response to hypertrophic stimuli requires nucleocytoplasmic shuttling of muscle LIM protein

(2009) Samuel Y. Boateng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Titin-based regulations of diastolic and systolic functions of mammalian cardiac muscle

(2009) Norio Fukuda et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Altered Contractility of Skeletal Muscle in Mice Deficient in Titin’s M-Band Region

(2009) Coen A.C. Ottenheijm et al.   JOURNAL OF MOLECULAR BIOLOGY

Calpain 1 Binding Capacities of the N1-Line Region of Titin Are Significantly Enhanced by Physiological Concentrations of Calcium†

(2008) Gerald Coulis et al.   BIOCHEMISTRY

Build it up-Tear it down: protein quality control in the cardiac sarcomere

(2008) M. S. Willis et al.   CARDIOVASCULAR RESEARCH

PICOT

(2008) Allen M. Samarel   CIRCULATION RESEARCH

PICOT Attenuates Cardiac Hypertrophy by Disrupting Calcineurin–NFAT Signaling

(2008) Dongtak Jeong et al.   CIRCULATION RESEARCH

Protein Kinase G Modulates Human Myocardial Passive Stiffness by Phosphorylation of the Titin Springs

(2008) Martina Krüger et al.   CIRCULATION RESEARCH

Titin Isoforms, Extracellular Matrix, and Global Chamber Remodeling in Experimental Dilated Cardiomyopathy

(2008) Wissam A. Jaber et al.   Circulation-Heart Failure

Rosiglitazone, but not glimepiride, improves myocardial diastolic function in association with reduction in oxidative stress in type 2 diabetic patients without overt heart disease

(2008) Helene Von Bibra et al.   Diabetes & Vascular Disease Research

Multiple Molecular Interactions Implicate the Connectin/Titin N2A Region as a Modulating Scaffold for p94/Calpain 3 Activity in Skeletal Muscle

(2008) Chikako Hayashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiplex Kinase Signaling Modifies Cardiac Function at the Level of Sarcomeric Proteins

(2008) R. John Solaro   JOURNAL OF BIOLOGICAL CHEMISTRY

An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice

(2008) Farah Sheikh et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutation that dramatically alters rat titin isoform expression and cardiomyocyte passive tension

(2008) Marion L. Greaser et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Evidence for the Oligomeric State of ‘Elastic’ Titin in Muscle Sarcomeres

(2008) Ahmed Houmeida et al.   JOURNAL OF MOLECULAR BIOLOGY

Mechanoenzymatics of titin kinase

(2008) E. M. Puchner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A regular pattern of Ig super-motifs defines segmental flexibility as the elastic mechanism of the titin chain

(2008) E. von Castelmur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thyroid Hormone Regulates Developmental Titin Isoform Transitions via the Phosphatidylinositol-3-Kinase/ AKT Pathway

(2007) Martina Krüger et al.   CIRCULATION RESEARCH