Hsp22 pretreatment protects against LPS-induced hippocampal injury by alleviating neuroinflammation and apoptosis by regulating the NLRP3/Caspase1/IL-1β signaling pathway in mice

Functional crosstalk between Long non-coding RNAs and the NLRP3 inflammasome in the regulation of diseases

(2021) Deqiang Luo et al.   MOLECULAR IMMUNOLOGY

Dexmedetomidine Mitigated NLRP3-Mediated Neuroinflammation via the Ubiquitin-Autophagy Pathway to Improve Perioperative Neurocognitive Disorder in Mice

(2021) Lieliang Zhang et al.   Frontiers in Pharmacology

Heat shock protein 22 modulates NRF1/TFAM-dependent mitochondrial biogenesis and DRP1-sparked mitochondrial apoptosis through AMPK-PGC1α signaling pathway to alleviate the early brain injury of subarachnoid hemorrhage in rats

(2021) Haiyan Fan et al.   Redox Biology

MicroRNA-138-5p Regulates Hippocampal Neuroinflammation and Cognitive Impairment by NLRP3/Caspase-1 Signaling Pathway in Rats

(2021) Xiaojin Feng et al.   Journal of Inflammation Research

Hsp22 ameliorates lipopolysaccharide-induced myocardial injury by inhibiting inflammation, oxidative stress, and apoptosis

(2021) Yun Yu et al.   Bioengineered

Cortical Overlap and Cortical-Hippocampal Interactions Predict Subsequent True and False Memory

(2020) Erik A. Wing et al.   JOURNAL OF NEUROSCIENCE

Chikusetsu saponin IVa alleviated sevoflurane-induced neuroinflammation and cognitive impairment by blocking NLRP3/caspase-1 pathway

(2020) Anmin Shao et al.   Pharmacological Reports

G-Protein-Coupled Receptors in CNS: A Potential Therapeutic Target for Intervention in Neurodegenerative Disorders and Associated Cognitive Deficits

(2020) Shofiul Azam et al.   Cells

Inhibiting NLRP3 inflammasome with MCC950 ameliorates perioperative neurocognitive disorders, suppressing neuroinflammation in the hippocampus in aged mice

(2020) Qun Fu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Heat Shock Protein 22 Attenuates Doxorubicin-Induced Cardiotoxicity via Regulating Inflammation and Apoptosis

(2020) Yin Lan et al.   Frontiers in Pharmacology

Neuroinflammation: An overview of neurodegenerative and metabolic diseases and of biotechnological studies

(2020) Ana Paula de Araújo Boleti et al.   NEUROCHEMISTRY INTERNATIONAL

Banhasasim-Tang Attenuates Lipopolysaccharide-Induced Cognitive Impairment by Suppressing Neuroinflammation in Mice

(2020) You-Chang Oh et al.   Nutrients

Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes

(2020) Hyuk Sung Kwon et al.   Translational Neurodegeneration

Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution

(2019) Takahiro Masuda et al.   NATURE

MicroRNA-146a protects against cognitive decline induced by surgical trauma by suppressing hippocampal neuroinflammation in mice

(2019) Lei Chen et al.   BRAIN BEHAVIOR AND IMMUNITY

Plasma VCAM1 levels correlate with disease severity in Parkinson’s disease

(2019) Caroline Perner et al.   Journal of Neuroinflammation

Inflammation and cerebral small vessel disease: A systematic review

(2019) Audrey Low et al.   AGEING RESEARCH REVIEWS

BAP31 regulates IRAK1-dependent neuroinflammation in microglia

(2019) Xia Liu et al.   Journal of Neuroinflammation

Effects of in utero exposure to lanthanum on neurological behavior in rat offspring

(2019) Xiao Xiao et al.   NEUROTOXICOLOGY AND TERATOLOGY

MG53 attenuates lipopolysaccharide-induced neurotoxicity and neuroinflammation via inhibiting TLR4/NF-κB pathway in vitro and in vivo

(2019) Fangxia Guan et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States

(2018) Mark P. Mattson et al.   Cell Metabolism

Alzheimer’s Disease, Oligomers, and Inflammation

(2018) Gianluigi Forloni et al.   JOURNAL OF ALZHEIMERS DISEASE

Critical role of NLRP3-caspase-1 pathway in age-dependent isoflurane-induced microglial inflammatory response and cognitive impairment

(2018) Zhi Wang et al.   Journal of Neuroinflammation

AMP-Activated Protein Kinase Regulation of the NLRP3 Inflammasome during Aging

(2018) Mario D. Cordero et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Inhibitory effect of INT-777 on lipopolysaccharide-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice

(2018) Xian Wu et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Lactobacilli-fermented cow's milk attenuated lipopolysaccharide-induced neuroinflammation and memory impairment in vitro and in vivo

(2017) Nurul Huda Musa et al.   JOURNAL OF DAIRY RESEARCH

Inhibition of AGEs/RAGE/Rho/ROCK pathway suppresses non-specific neuroinflammation by regulating BV2 microglial M1/M2 polarization through the NF-κB pathway

(2017) Jingkao Chen et al.   JOURNAL OF NEUROIMMUNOLOGY

Pleiotrophin regulates microglia-mediated neuroinflammation

(2017) Rosalía Fernández-Calle et al.   Journal of Neuroinflammation

Acetaminophen attenuates lipopolysaccharide-induced cognitive impairment through antioxidant activity

(2017) Wei-Xing Zhao et al.   Journal of Neuroinflammation

Tat-HSP22 inhibits oxidative stress-induced hippocampal neuronal cell death by regulation of the mitochondrial pathway

(2017) Hyo Sang Jo et al.   Molecular Brain

Neuroinflammation in Alzheimer's disease: Current evidence and future directions

(2016) Valeria Calsolaro et al.   Alzheimers & Dementia

Role of neuroinflammation in neurodegenerative diseases (Review)

(2016) WEI-WEI CHEN et al.   Molecular Medicine Reports

MeCP2 SUMOylation rescues Mecp2-mutant-induced behavioural deficits in a mouse model of Rett syndrome

(2016) Derek J. C. Tai et al.   Nature Communications

Regulation by heat shock protein 22 (HSPB8) of transforming growth factor-α-induced ovary cancer cell migration

(2015) Mariko Suzuki et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Distinct and simultaneously active plasticity mechanisms in mouse hippocampus during different phases of Morris water maze training

(2014) Annelies Laeremans et al.   Brain Structure & Function

The common inflammatory etiology of depression and cognitive impairment: a therapeutic target

(2014) David J Allison et al.   Journal of Neuroinflammation

Systemic injection of LPS induces region-specific neuroinflammation and mitochondrial dysfunction in normal mouse brain

(2014) Haneul Noh et al.   NEUROCHEMISTRY INTERNATIONAL

Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant

(2014) Takashi Ayaki et al.   Acta Neuropathologica Communications

Sepsis-induced brain dysfunction

(2013) Nicolas Adam et al.   Expert Review of Anti-Infective Therapy

Interleukin-1 beta converting enzyme is necessary for development of depression-like behavior following intracerebroventricular administration of lipopolysaccharide to mice

(2013) Marcus A Lawson et al.   Journal of Neuroinflammation

Cardiac H11 kinase/Hsp22 stimulates oxidative phosphorylation and modulates mitochondrial reactive oxygen species production: Involvement of a nitric oxide-dependent mechanism

(2012) Lydie Laure et al.   FREE RADICAL BIOLOGY AND MEDICINE

HSP22 and its Role in Human Neurological Disease

(2011) Xiaomei Guan et al.   CURRENT NEUROVASCULAR RESEARCH

Small Heat-Shock Protein HSPB1 Mutants Stabilize Microtubules in Charcot-Marie-Tooth Neuropathy

(2011) L. Almeida-Souza et al.   JOURNAL OF NEUROSCIENCE

Obovatol attenuates LPS-induced memory impairments in mice via inhibition of NF-κB signaling pathway

(2011) Dong-Young Choi et al.   NEUROCHEMISTRY INTERNATIONAL

A role of small heat shock protein B8 (HspB8) in the autophagic removal of misfolded proteins responsible for neurodegenerative diseases

(2010) Valeria Crippa et al.   Autophagy

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

The role of lipopolysaccharide/toll-like receptor 4 signaling in chronic liver diseases

(2010) João-Bruno Soares et al.   Hepatology International

Central Administration of Lipopolysaccharide Induces Depressive-like Behavior in Vivo and Activates Brain Indoleamine 2,3 Dioxygenase In Murine Organotypic Hippocampal Slice Cultures

(2010) Xin Fu et al.   Journal of Neuroinflammation

IL-33 Enhances Lipopolysaccharide-Induced Inflammatory Cytokine Production from Mouse Macrophages by Regulating Lipopolysaccharide Receptor Complex

(2009) Q. Espinassous et al.   JOURNAL OF IMMUNOLOGY

Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism

(2008) Alexander Semmler et al.   Journal of Neuroinflammation

Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation

(2008) Jae Lee et al.   Journal of Neuroinflammation

Structure, properties, and functions of the human small heat-shock protein HSP22 (HspB8, H11, E2IG1): A critical review

(2007) Anton A. Shemetov et al.   JOURNAL OF NEUROSCIENCE RESEARCH