- Home
- Publications
- Publication Search
- Publication Details
Title
Dual roles of UPRer and UPRmt in neurodegenerative diseases
Authors
Keywords
-
Journal
JOURNAL OF MOLECULAR MEDICINE-JMM
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-10-11
DOI
10.1007/s00109-023-02382-9
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- c-Jun N-Terminal Kinase Promotes Stress Granule Assembly and Neurodegeneration in C9orf72-Mediated ALS and FTD
- (2023) Talanjeri Gopalakrishna Sahana et al. JOURNAL OF NEUROSCIENCE
- The unfolded protein response transcription factor XBP1s ameliorates Alzheimer’s disease by improving synaptic function and proteostasis
- (2023) Claudia Duran-Aniotz et al. MOLECULAR THERAPY
- Stress response mechanisms in protein misfolding diseases: Profiling a cellular model of Huntington's disease
- (2023) Liliana M. Almeida et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- The Protective Effect of Edaravone on TDP-43 Plus Oxidative Stress-Induced Neurotoxicity in Neuronal Cells: Analysis of Its Neuroprotective Mechanisms Using RNA Sequencing
- (2022) Aki Soejima-Kusunoki et al. Pharmaceuticals
- Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer’s disease
- (2021) Liang He et al. Translational Psychiatry
- Establishment of a reporter system for monitoring activation of the ER stress transducer ATF6β
- (2021) Le Thi Hien et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state
- (2021) Semra Smajić et al. BRAIN
- Activation of Mitochondrial Unfolded Protein Response in SHSY5Y Expressing APP Cells and APP/PS1 Mice
- (2020) Yang Shen et al. Frontiers in Cellular Neuroscience
- Mechanisms, regulation and functions of the unfolded protein response
- (2020) Claudio Hetz et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Fine tuning of the unfolded protein response by ISRIB improves neuronal survival in a model of amyotrophic lateral sclerosis
- (2020) Ricardo Bugallo et al. Cell Death & Disease
- Common gene expression signatures in Parkinson’s disease are driven by changes in cell composition
- (2020) Gonzalo S. Nido et al. Acta Neuropathologica Communications
- Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer’s disease-like pathology in human cerebral organoids
- (2020) María José Pérez et al. MOLECULAR PSYCHIATRY
- Synergy between amyloid-β and tau in Alzheimer’s disease
- (2020) Marc Aurel Busche et al. NATURE NEUROSCIENCE
- Folding the Mitochondrial UPR into the Integrated Stress Response
- (2020) Nadine S. Anderson et al. TRENDS IN CELL BIOLOGY
- Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models
- (2020) Ying-Wooi Wan et al. Cell Reports
- Endoplasmic Reticulum Stress and Unfolded Protein Response in Neurodegenerative Diseases
- (2020) Rose Ghemrawi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Mitochondrial Unfolded Protein Response: A Hinge Between Healthy and Pathological Aging
- (2020) Francisco Muñoz-Carvajal et al. Frontiers in Aging Neuroscience
- Mitochondrial unfolded protein response: An emerging pathway in human diseases
- (2020) Li Zhu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mitochondrial UPR repression duringPseudomonas aeruginosainfection requires the bZIP protein ZIP-3
- (2019) Pan Deng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The UPR-PERK pathway is not a promising therapeutic target for mutant SOD1-induced ALS
- (2019) Yulia Dzhashiashvili et al. NEUROBIOLOGY OF DISEASE
- Mutant huntingtin inhibits the mitochondrial unfolded protein response by impairing ABCB10 mRNA stability
- (2019) Zixing Fu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity
- (2019) Di Hu et al. ACTA NEUROPATHOLOGICA
- Proteasomal and lysosomal clearance of faulty secretory proteins: ER-associated degradation (ERAD) and ER-to-lysosome-associated degradation (ERLAD) pathways
- (2019) Ilaria Fregno et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response
- (2019) Peng Wang et al. PLoS Genetics
- Atf6α impacts cell number by influencing survival, death and proliferation
- (2019) Rohit B. Sharma et al. Molecular Metabolism
- Neurochemical biomarkers in amyotrophic lateral sclerosis
- (2019) Federico Verde et al. CURRENT OPINION IN NEUROLOGY
- Parkinson disease
- (2019) R. Balestrino et al. EUROPEAN JOURNAL OF NEUROLOGY
- Activation of the Unfolded Protein Response and Proteostasis Disturbance in Parkinsonism-Dementia of Guam
- (2019) Bert M Verheijen et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- IRE1 promotes neurodegeneration through autophagy-dependent neuron death in the Drosophila model of Parkinson’s disease
- (2019) Cheng Yan et al. Cell Death & Disease
- Constitutive XBP-1s-mediated activation of the endoplasmic reticulum unfolded protein response protects against pathological tau
- (2019) Sarah M. Waldherr et al. Nature Communications
- Ginseng protein protects against mitochondrial dysfunction and neurodegeneration by inducing mitochondrial unfolded protein response in Drosophila melanogaster PINK1 model of Parkinson's disease
- (2019) Meichen Liu et al. JOURNAL OF ETHNOPHARMACOLOGY
- Knockdown of GADD34 in neonatal mutant SOD1 mice ameliorates ALS
- (2019) Ghanashyam D. Ghadge et al. NEUROBIOLOGY OF DISEASE
- UPRmt regulation and output: a stress response mediated by mitochondrial-nuclear communication
- (2018) Andrew Melber et al. CELL RESEARCH
- Targeting PERK signaling with the small molecule GSK2606414 prevents neurodegeneration in a model of Parkinson's disease
- (2018) Gabriela Mercado et al. NEUROBIOLOGY OF DISEASE
- C9ORF72 GGGGCC repeat-associated non-AUG translation is upregulated by stress through eIF2α phosphorylation
- (2018) Weiwei Cheng et al. Nature Communications
- The different axes of the mammalian mitochondrial unfolded protein response
- (2018) Christian Münch BMC BIOLOGY
- Tauopathy-Associated PERK Alleles are Functional Hypomorphs that Increase Neuronal Vulnerability to ER Stress
- (2018) Shauna H Yuan et al. HUMAN MOLECULAR GENETICS
- FUS interacts with ATP synthase beta subunit and induces mitochondrial unfolded protein response in cellular and animal models
- (2018) Jianwen Deng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Early Events in the Endoplasmic Reticulum Unfolded Protein Response
- (2018) Steffen Preissler et al. Cold Spring Harbor Perspectives in Biology
- Huntington's disease: a clinical review
- (2017) P. McColgan et al. EUROPEAN JOURNAL OF NEUROLOGY
- The endoplasmic reticulum: A hub of protein quality control in health and disease
- (2017) Lisa Vincenz-Donnelly et al. FREE RADICAL BIOLOGY AND MEDICINE
- Sex specific activation of the ERα axis of the mitochondrial UPR (UPRmt) in the G93A-SOD1 mouse model of familial ALS
- (2017) Amanjot K Riar et al. HUMAN MOLECULAR GENETICS
- Alpha-synuclein induces the unfolded protein response in Parkinson’s disease SNCA triplication iPSC-derived neurons
- (2017) Sabrina M Heman-Ackah et al. HUMAN MOLECULAR GENETICS
- Dysregulation of the Mitochondrial Unfolded Protein Response Induces Non-Apoptotic Dopaminergic Neurodegeneration inC. elegansModels of Parkinson's Disease
- (2017) Bryan A. Martinez et al. JOURNAL OF NEUROSCIENCE
- Cytosolic proteostasis through importing of misfolded proteins into mitochondria
- (2017) Linhao Ruan et al. NATURE
- Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity
- (2017) Vincenzo Sorrentino et al. NATURE
- Regulating Secretory Proteostasis through the Unfolded Protein Response: From Function to Therapy
- (2017) Lars Plate et al. TRENDS IN CELL BIOLOGY
- Pathology of Neurodegenerative Diseases
- (2017) Brittany N. Dugger et al. Cold Spring Harbor Perspectives in Biology
- Activation of the mitochondrial unfolded protein response promotes longevity and dopamine neuron survival in Parkinson’s disease models
- (2017) Jason F. Cooper et al. Scientific Reports
- Evidence for Mitochondrial UPR Gene Activation in Familial and Sporadic Alzheimer's Disease
- (2016) John S. Beck et al. Current Alzheimer Research
- The Transcription Factor ATF5 Mediates a Mammalian Mitochondrial UPR
- (2016) Christopher J. Fiorese et al. CURRENT BIOLOGY
- The transcription factor XBP1s restores hippocampal synaptic plasticity and memory by control of the Kalirin-7 pathway in Alzheimer model
- (2016) M Cissé et al. MOLECULAR PSYCHIATRY
- Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis
- (2016) Sebum Lee et al. NEURON
- PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia
- (2015) Helois Radford et al. ACTA NEUROPATHOLOGICA
- A conformational RNA zipper promotes intron ejection during non-conventional XBP1 mRNA splicing
- (2015) J. Peschek et al. EMBO REPORTS
- ENC1 Modulates the Aggregation and Neurotoxicity of Mutant Huntingtin Through p62 Under ER Stress
- (2015) Huikyong Lee et al. MOLECULAR NEUROBIOLOGY
- Proteostasis control by the unfolded protein response
- (2015) Claudio Hetz et al. NATURE CELL BIOLOGY
- Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS
- (2015) Mercedes Prudencio et al. NATURE NEUROSCIENCE
- α-Synuclein-mediated inhibition of ATF6 processing into COPII vesicles disrupts UPR signaling in Parkinson's disease
- (2015) Joel J. Credle et al. NEUROBIOLOGY OF DISEASE
- LON is the master protease that protects against protein aggregation in human mitochondria through direct degradation of misfolded proteins
- (2015) Ayenachew Bezawork-Geleta et al. Scientific Reports
- Axonally Synthesized ATF4 Transmits a Neurodegenerative Signal across Brain Regions
- (2014) Jimena Baleriola et al. CELL
- The Protein Import Machinery of Mitochondria—A Regulatory Hub in Metabolism, Stress, and Disease
- (2014) Angelika B. Harbauer et al. Cell Metabolism
- Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis
- (2014) H.-Q. Jiang et al. NEUROSCIENCE
- Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1
- (2014) P. Valdes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Unfolded protein response signaling by transcription factor XBP-1 regulates ADAM10 and is affected in Alzheimer's disease
- (2013) Sven Reinhardt et al. FASEB JOURNAL
- ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
- (2013) Jaeseok Han et al. NATURE CELL BIOLOGY
- Functional Contribution of the Transcription Factor ATF4 to the Pathogenesis of Amyotrophic Lateral Sclerosis
- (2013) Soledad Matus et al. PLoS One
- Soluble forms of polyQ-expanded huntingtin rather than large aggregates cause endoplasmic reticulum stress
- (2013) Julia Leitman et al. Nature Communications
- AAV-mediated delivery of the transcription factor XBP1s into the striatum reduces mutant Huntingtin aggregation in a mouse model of Huntington’s disease
- (2012) Amparo Zuleta et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The unfolded protein response in models of human mutant G93A amyotrophic lateral sclerosis
- (2012) T. Prell et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy
- (2012) Rene L. Vidal et al. HUMAN MOLECULAR GENETICS
- IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux
- (2011) Huikyong Lee et al. HUMAN MOLECULAR GENETICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More