Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS
Authors
Keywords
-
Journal
NATURE NEUROSCIENCE
Volume 18, Issue 8, Pages 1175-1182
Publisher
Springer Nature
Online
2015-07-21
DOI
10.1038/nn.4065
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Nucleolar stress and impaired stress granule formation contribute to C9orf72 RAN translation-induced cytotoxicity
- (2015) Zhouteng Tao et al. HUMAN MOLECULAR GENETICS
- Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress
- (2014) Yong-Jie Zhang et al. ACTA NEUROPATHOLOGICA
- C9orf72 FTLD/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestration
- (2014) Stephanie May et al. ACTA NEUROPATHOLOGICA
- MAP-RSeq: Mayo Analysis Pipeline for RNA sequencing
- (2014) Krishna R Kalari et al. BMC BIOINFORMATICS
- Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions
- (2014) Johnathan Cooper-Knock et al. BRAIN
- Characterization of the dipeptide repeat protein in the molecular pathogenesis of c9FTD/ALS
- (2014) Mai Yamakawa et al. HUMAN MOLECULAR GENETICS
- Patterns of cerebral and cerebellar white matter degeneration in ALS: Figure 1
- (2014) P Bede et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Loss of MBNL Leads to Disruption of Developmentally Regulated Alternative Polyadenylation in RNA-Mediated Disease
- (2014) Ranjan Batra et al. MOLECULAR CELL
- Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis
- (2014) Janel O Johnson et al. NATURE NEUROSCIENCE
- Ataxin-2 as potential disease modifier in C9ORF72 expansion carriers
- (2014) Marka van Blitterswijk et al. NEUROBIOLOGY OF AGING
- Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal Death
- (2014) Xinmei Wen et al. NEURON
- Cerebellar Integrity in the Amyotrophic Lateral Sclerosis - Frontotemporal Dementia Continuum
- (2014) Rachel H. Tan et al. PLoS One
- C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins
- (2014) S. Mizielinska et al. SCIENCE
- Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells
- (2014) I. Kwon et al. SCIENCE
- Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3′-UTR landscape across seven tumour types
- (2014) Zheng Xia et al. Nature Communications
- Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins
- (2013) Kohji Mori et al. ACTA NEUROPATHOLOGICA
- Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS
- (2013) Tania F. Gendron et al. ACTA NEUROPATHOLOGICA
- hnRNP A3 binds to GGGGCC repeats and is a constituent of p62-positive/TDP43-negative inclusions in the hippocampus of patients with C9orf72 mutations
- (2013) Kohji Mori et al. ACTA NEUROPATHOLOGICA
- A compendium of RNA-binding motifs for decoding gene regulation
- (2013) Debashish Ray et al. NATURE
- Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
- (2013) Hong Joo Kim et al. NATURE
- Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS
- (2013) Peter E.A. Ash et al. NEURON
- RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention
- (2013) Christopher J. Donnelly et al. NEURON
- OLego: fast and sensitive mapping of spliced mRNA-Seq reads using small seeds
- (2013) Jie Wu et al. NUCLEIC ACIDS RESEARCH
- Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration
- (2013) C. Lagier-Tourenne et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS
- (2013) K. Mori et al. SCIENCE
- Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion
- (2013) D. Sareen et al. Science Translational Medicine
- Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic
- (2013) Youn-Bok Lee et al. Cell Reports
- Characterization of frontotemporal dementia and/or amyotrophic lateral sclerosis associated with the GGGGCC repeat expansion in C9ORF72
- (2012) Bradley F. Boeve et al. BRAIN
- The Poly(A)-Binding Protein Nuclear 1 Suppresses Alternative Cleavage and Polyadenylation Sites
- (2012) Mathias Jenal et al. CELL
- How do C9ORF72 repeat expansions cause amyotrophic lateral sclerosis and frontotemporal dementia
- (2012) Marka van Blitterswijk et al. CURRENT OPINION IN NEUROLOGY
- Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis
- (2012) Julien Couthouis et al. HUMAN MOLECULAR GENETICS
- Cognitive decline and reduced survival inC9orf72expansion frontotemporal degeneration and amyotrophic lateral sclerosis
- (2012) David J Irwin et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Muscleblind-like 2-Mediated Alternative Splicing in the Developing Brain and Dysregulation in Myotonic Dystrophy
- (2012) Konstantinos Charizanis et al. NEURON
- STRING v9.1: protein-protein interaction networks, with increased coverage and integration
- (2012) Andrea Franceschini et al. NUCLEIC ACIDS RESEARCH
- Alternative polyadenylation: New insights from global analyses
- (2012) Y. Shi RNA
- Longitudinal neuroimaging and neuropsychological profiles of frontotemporal dementia with C9ORF72 expansions
- (2012) Colin J Mahoney et al. Alzheimers Research & Therapy
- Integrative Genome-wide Analysis Reveals Cooperative Regulation of Alternative Splicing by hnRNP Proteins
- (2012) Stephanie C. Huelga et al. Cell Reports
- Clinical and neuropathologic heterogeneity of c9FTD/ALS associated with hexanucleotide repeat expansion in C9ORF72
- (2011) Melissa E. Murray et al. ACTA NEUROPATHOLOGICA
- Mutational analysis reveals the FUS homolog TAF15 as a candidate gene for familial amyotrophic lateral sclerosis
- (2011) N. Ticozzi et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- MEME-ChIP: motif analysis of large DNA datasets
- (2011) Philip Machanick et al. BIOINFORMATICS
- Neuropathologically defined subtypes of Alzheimer's disease with distinct clinical characteristics: a retrospective study
- (2011) Melissa E Murray et al. LANCET NEUROLOGY
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
- (2010) Andrew C. Elden et al. NATURE
- Review: Transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration
- (2010) T. F. Gendron et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- AltAnalyze and DomainGraph: analyzing and visualizing exon expression data
- (2010) Dorothea Emig et al. NUCLEIC ACIDS RESEARCH
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
- Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity
- (2009) Y.-J. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
- (2009) C. Vance et al. SCIENCE
- Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
- (2009) T. J. Kwiatkowski et al. SCIENCE
- Evidence of Multisystem Disorder in Whole-Brain Map of Pathological TDP-43 in Amyotrophic Lateral Sclerosis
- (2008) Felix Geser et al. ARCHIVES OF NEUROLOGY
- Frontal Paralimbic Network Atrophy in Very Mild Behavioral Variant Frontotemporal Dementia
- (2008) William W. Seeley et al. ARCHIVES OF NEUROLOGY
- WGCNA: an R package for weighted correlation network analysis
- (2008) Peter Langfelder et al. BMC BIOINFORMATICS
- TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2008) J. Sreedharan et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search