Activation of the Unfolded Protein Response and Proteostasis Disturbance in Parkinsonism-Dementia of Guam
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Activation of the Unfolded Protein Response and Proteostasis Disturbance in Parkinsonism-Dementia of Guam
Authors
Keywords
-
Journal
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
Volume -, Issue -, Pages -
Publisher
Oxford University Press (OUP)
Online
2019-11-21
DOI
10.1093/jnen/nlz110
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair
- (2019) Joseph R. Klim et al. NATURE NEUROSCIENCE
- Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report
- (2019) Peter T Nelson et al. BRAIN
- The proteasome biogenesis regulator Rpn4 cooperates with the unfolded protein response to promote ER stress resistance
- (2019) Rolf M Schmidt et al. eLife
- TDP-43 controls lysosomal pathways thereby determining its own clearance and cytotoxicity
- (2018) Christine Leibiger et al. HUMAN MOLECULAR GENETICS
- Mechanism and medical implications of mammalian autophagy
- (2018) Ivan Dikic et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing
- (2018) Barry Boland et al. NATURE REVIEWS DRUG DISCOVERY
- Paradoxical effects of mutant ubiquitin on Aβ plaque formation in an Alzheimer mouse model
- (2018) Bert M. Verheijen et al. NEUROBIOLOGY OF AGING
- Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy
- (2017) Roberta Cascella et al. FASEB JOURNAL
- ER stress and the unfolded protein response in neurodegeneration
- (2017) Claudio Hetz et al. Nature Reviews Neurology
- Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities
- (2017) Fiona M. Menzies et al. NEURON
- Deposition of mutant ubiquitin in parkinsonism–dementia complex of Guam
- (2017) Bert M. Verheijen et al. Acta Neuropathologica Communications
- Granulovacuolar degeneration: a neurodegenerative change that accompanies tau pathology
- (2016) Christoph Köhler ACTA NEUROPATHOLOGICA
- Protein misfolding in the endoplasmic reticulum as a conduit to human disease
- (2016) Miao Wang et al. NATURE
- The unfolded protein response in neurodegenerative diseases: a neuropathological perspective
- (2015) Wiep Scheper et al. ACTA NEUROPATHOLOGICA
- p62/SQSTM1 functions as a signaling hub and an autophagy adaptor
- (2015) Yoshinori Katsuragi et al. FEBS Journal
- Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling
- (2015) Natura Myeku et al. NATURE MEDICINE
- cAMP-induced phosphorylation of 26S proteasomes on Rpn6/PSMD11 enhances their activity and the degradation of misfolded proteins
- (2015) Sudarsanareddy Lokireddy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Accumulation of Basic Amino Acids at Mitochondria Dictates the Cytotoxicity of Aberrant Ubiquitin
- (2015) Ralf J. Braun et al. Cell Reports
- Primary age-related tauopathy (PART): a common pathology associated with human aging
- (2014) John F. Crary et al. ACTA NEUROPATHOLOGICA
- Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species
- (2014) E. L. Scotter et al. JOURNAL OF CELL SCIENCE
- The lectin OS-9 delivers mutant neuroserpin to endoplasmic reticulum associated degradation in familial encephalopathy with neuroserpin inclusion bodies
- (2014) Angela Schipanski et al. NEUROBIOLOGY OF AGING
- Proteostasis impairment in protein-misfolding and -aggregation diseases
- (2014) Mark S. Hipp et al. TRENDS IN CELL BIOLOGY
- Direct cellular delivery of human proteasomes to delay tau aggregation
- (2014) Dong Hoon Han et al. Nature Communications
- The ubiquitin-proteasome system in neurodegenerative diseases: precipitating factor, yet part of the solution
- (2014) Nico P. Dantuma et al. Frontiers in Molecular Neuroscience
- Tau Accumulation Activates the Unfolded Protein Response by Impairing Endoplasmic Reticulum-Associated Degradation
- (2013) J. F. Abisambra et al. JOURNAL OF NEUROSCIENCE
- ALS-Associated TDP-43 Induces Endoplasmic Reticulum Stress, Which Drives Cytoplasmic TDP-43 Accumulation and Stress Granule Formation
- (2013) Adam K. Walker et al. PLoS One
- Tau degradation: The ubiquitin–proteasome system versus the autophagy-lysosome system
- (2013) Min Jae Lee et al. PROGRESS IN NEUROBIOLOGY
- Long-term proteasomal inhibition in transgenic mice by UBB+1 expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients
- (2012) Martin Irmler et al. ACTA NEUROPATHOLOGICA
- Motor Neuron-specific Disruption of Proteasomes, but Not Autophagy, Replicates Amyotrophic Lateral Sclerosis
- (2012) Yoshitaka Tashiro et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The ubiquitin proteasome system in neurodegenerative diseases: Culprit, accomplice or victim?
- (2012) F.J.A. Dennissen et al. PROGRESS IN NEUROBIOLOGY
- Endoplasmic reticulum stress activates autophagy but not the proteasome in neuronal cells: implications for Alzheimer's disease
- (2011) D A T Nijholt et al. CELL DEATH AND DIFFERENTIATION
- The unfolded protein response is associated with early tau pathology in the hippocampus of tauopathies
- (2011) Diana AT Nijholt et al. JOURNAL OF PATHOLOGY
- Elevated Proteasome Capacity Extends Replicative Lifespan in Saccharomyces cerevisiae
- (2011) Undine Kruegel et al. PLoS Genetics
- The Unfolded Protein Response Is Activated in Pretangle Neurons in Alzheimer's Disease Hippocampus
- (2009) Jeroen J.M. Hoozemans et al. AMERICAN JOURNAL OF PATHOLOGY
- Regulation Mechanisms and Signaling Pathways of Autophagy
- (2009) Congcong He et al. Annual Review of Genetics
- Mechanisms of cross-talk between the ubiquitin-proteasome and autophagy-lysosome systems
- (2009) Viktor I. Korolchuk et al. FEBS LETTERS
- Modest proteasomal inhibition by aberrant ubiquitin exacerbates aggregate formation in a Huntington disease mouse model
- (2009) Remko de Pril et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Disease-Associated Mutant Ubiquitin Causes Proteasomal Impairment and Enhances the Toxicity of Protein Aggregates
- (2009) Elizabeth M. H. Tank et al. PLoS Genetics
- Long-term proteasome dysfunction in the mouse brain by expression of aberrant ubiquitin
- (2008) David F. Fischer et al. NEUROBIOLOGY OF AGING
- Proteasome subunit proteins and neuropathology in tauopathies and synucleinopathies: Consequences for proteomic analyses
- (2008) Mohamed Zouambia et al. PROTEOMICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started