Breaking down the cellular responses to type I interferon neurotoxicity in the brain
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Breaking down the cellular responses to type I interferon neurotoxicity in the brain
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 14, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2023-02-03
DOI
10.3389/fimmu.2023.1110593
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques
- (2022) Ethan R. Roy et al. IMMUNITY
- The cytokines interleukin-6 and interferon-α induce distinct microglia phenotypes
- (2022) Phillip K. West et al. Journal of Neuroinflammation
- Oral surveillance and JAK inhibitor safety: the theory of relativity
- (2022) Kevin L. Winthrop et al. Nature Reviews Rheumatology
- Janus Kinase Inhibitors in the Treatment of Type I Interferonopathies: A Case Series From a Single Center in China
- (2022) Wendao Li et al. Frontiers in Immunology
- Alpha-synuclein supports type 1 interferon signalling in neurons and brain tissue
- (2022) Brendan Monogue et al. BRAIN
- ADAR1 mutation causes ZBP1-dependent immunopathology
- (2022) Nicholas W. Hubbard et al. NATURE
- ADAR1 averts fatal type I interferon induction by ZBP1
- (2022) Huipeng Jiao et al. NATURE
- ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation
- (2022) Richard de Reuver et al. NATURE
- Normal Aging Induces Changes in the Brain and Neurodegeneration Progress: Review of the Structural, Biochemical, Metabolic, Cellular, and Molecular Changes
- (2022) Jiseon Lee et al. Frontiers in Aging Neuroscience
- Impaired type I interferon signaling activity implicated in the peripheral blood transcriptome of preclinical Alzheimer's disease
- (2022) Liting Song et al. EBioMedicine
- Treatment of Down Syndrome-Associated Arthritis with JAK Inhibition
- (2022) Jordan T. Jones Case Reports in Rheumatology
- Why Do We Need JAK Inhibitors in Systemic Lupus Erythematosus?
- (2022) Patricia Richter et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Microglia shield the murine brain from damage mediated by the cytokines IL-6 and IFN-α
- (2022) Phillip K. West et al. Frontiers in Immunology
- A Randomized, Placebo‐Controlled Phase III Extension Trial of the Long‐Term Safety and Tolerability of Anifrolumab in Active Systemic Lupus Erythematosus
- (2022) Kenneth C. Kalunian et al. Arthritis & Rheumatology
- Prior activation state shapes the microglia response to antihuman TREM2 in a mouse model of Alzheimer’s disease
- (2021) Daniel C. Ellwanger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dirty Fish Versus Squeaky Clean Mice: Dissecting Interspecies Differences Between Animal Models of Interferonopathy
- (2021) Holly A. Rutherford et al. Frontiers in Immunology
- JAK inhibition for treatment of psoriatic arthritis in Down syndrome
- (2021) Andrew T Pham et al. RHEUMATOLOGY
- Signaling Through Nucleic Acid Sensors and Their Roles in Inflammatory Diseases
- (2021) Haruna Okude et al. Frontiers in Immunology
- Interferons and Multiple Sclerosis: Lessons from 25 Years of Clinical and Real-World Experience with Intramuscular Interferon Beta-1a (Avonex)
- (2021) Stanley L. Cohan et al. CNS DRUGS
- Cerebrospinal fluid neopterin as a biomarker of treatment response to Janus kinase inhibition in Aicardi–Goutières syndrome
- (2021) Velda X Han et al. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
- Traumatic brain injury results in unique microglial and astrocyte transcriptomes enriched for type I interferon response
- (2021) Brittany P. Todd et al. Journal of Neuroinflammation
- Antimicrobial immunity impedes CNS vascular repair following brain injury
- (2021) Panagiotis Mastorakos et al. NATURE IMMUNOLOGY
- Neuroinflammatory astrocyte subtypes in the mouse brain
- (2021) Philip Hasel et al. NATURE NEUROSCIENCE
- Blood-Brain Barrier Dysfunction Amplifies the Development of Neuroinflammation: Understanding of Cellular Events in Brain Microvascular Endothelial Cells for Prevention and Treatment of BBB Dysfunction
- (2021) Fuyuko Takata et al. Frontiers in Cellular Neuroscience
- A novel phosphoproteomic landscape evoked in response to type I interferon in the brain and in glial cells
- (2021) Barney Viengkhou et al. Journal of Neuroinflammation
- Case Report: The JAK-Inhibitor Ruxolitinib Use in Aicardi-Goutieres Syndrome Due to ADAR1 Mutation
- (2021) Marco Cattalini et al. Frontiers in Pediatrics
- Intrinsic Interferon Signaling Regulates the Cell Death and Mesenchymal Phenotype of Glioblastoma Stem Cells
- (2021) Sabbir Khan et al. Cancers
- Single-Cell Transcriptome Atlas of Murine Endothelial Cells
- (2020) Joanna Kalucka et al. CELL
- Interferon-β plays a detrimental role in experimental traumatic brain injury by enhancing neuroinflammation that drives chronic neurodegeneration
- (2020) James P. Barrett et al. JOURNAL OF NEUROSCIENCE
- JAK Inhibitor Therapy in a Child with Inherited USP18 Deficiency
- (2020) Fahad Alsohime et al. NEW ENGLAND JOURNAL OF MEDICINE
- Interferon mediated neuroinflammation in polyglutamine disease is not caused by RNA toxicity
- (2020) Aksheev Bhambri et al. Cell Death & Disease
- Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion
- (2020) Jason R. Plemel et al. Science Advances
- Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease
- (2020) Ethan R. Roy et al. JOURNAL OF CLINICAL INVESTIGATION
- Molecular mechanisms and cellular functions of cGAS–STING signalling
- (2020) Karl-Peter Hopfner et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Type I Interferon Receptor Signaling in Astrocytes Regulates Hippocampal Synaptic Plasticity and Cognitive Function of the Healthy CNS
- (2020) Shirin Hosseini et al. Cell Reports
- Systemic Type I IFN Inflammation in Human ISG15 Deficiency Leads to Necrotizing Skin Lesions
- (2020) Marta Martin-Fernandez et al. Cell Reports
- Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation
- (2020) Hyeseung Lee et al. NEURON
- Cyclic GMP-AMP synthase promotes the inflammatory and autophagy responses in Huntington disease
- (2020) Manish Sharma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Absence of Neuronal Autoantibodies in Neuropsychiatric Systemic Lupus Erythematosus
- (2020) James A. Varley et al. ANNALS OF NEUROLOGY
- TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS
- (2020) Chien-Hsiung Yu et al. CELL
- Janus Kinase Inhibition in the Aicardi–Goutières Syndrome
- (2020) Adeline Vanderver et al. NEW ENGLAND JOURNAL OF MEDICINE
- Minocycline in neurodegenerative and psychiatric diseases: An update
- (2020) Diego Romero‐Miguel et al. EUROPEAN JOURNAL OF NEUROLOGY
- Herpes simplex encephalitis in a patient with a distinctive form of inherited IFNAR1 deficiency
- (2020) Paul Bastard et al. JOURNAL OF CLINICAL INVESTIGATION
- cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing
- (2020) Carolina Uggenti et al. NATURE GENETICS
- Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease
- (2020) Marta Olah et al. Nature Communications
- Chronic neurodegeneration induces type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression
- (2019) Arshed Nazmi et al. GLIA
- Interferon-alpha-induced depression: Comparisons between early- and late-onset subgroups and with patients with major depressive disorder
- (2019) Kuan-Pin Su et al. BRAIN BEHAVIOR AND IMMUNITY
- Microglia responses to interleukin‐6 and type I interferons in neuroinflammatory disease
- (2019) Phillip K. West et al. GLIA
- Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines
- (2019) Massimo Filippi et al. BRAIN
- Treatments in Aicardi–Goutières syndrome
- (2019) Yanick J Crow et al. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
- Diagnosis, prognosis, and treatment of leukodystrophies
- (2019) Marjo S van der Knaap et al. LANCET NEUROLOGY
- Neuroinflammation — a common thread in neurological disorders
- (2019) Nils Erik Gilhus et al. Nature Reviews Neurology
- Intranasal interferon beta improves memory and modulates inflammatory responses in a mutant APP-overexpressing rat model of Alzheimer’s disease
- (2019) Sara Chavoshinezhad et al. BRAIN RESEARCH BULLETIN
- Imiquimod and interferon-alpha augment monocyte-mediated astrocyte secretion of MCP-1, IL-6 and IP-10 in a human co-culture system
- (2019) Michael D. Rizzo et al. JOURNAL OF NEUROIMMUNOLOGY
- Anti-IFNAR treatment does not reverse neuropsychiatric disease in MRL/lpr lupus mice
- (2019) M W Huang et al. LUPUS
- Viral infections and the neonatal brain
- (2019) Linda S. de Vries Seminars in Pediatric Neurology
- Traumatic Brain Injuries: Pathophysiology and Potential Therapeutic Targets
- (2019) Si Yun Ng et al. Frontiers in Cellular Neuroscience
- Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors
- (2019) Rani K. Powers et al. Nature Communications
- Mass Cytometry Reveals Global Immune Remodeling with Multi-lineage Hypersensitivity to Type I Interferon in Down Syndrome
- (2019) Katherine A. Waugh et al. Cell Reports
- Type III interferons: Balancing tissue tolerance and resistance to pathogen invasion
- (2019) Achille Broggi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Trial of Anifrolumab in Active Systemic Lupus Erythematosus
- (2019) Eric F. Morand et al. NEW ENGLAND JOURNAL OF MEDICINE
- Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction
- (2019) Vladimir V. Senatorov et al. Science Translational Medicine
- Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes
- (2018) Akira Sobue et al. GLIA
- JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies
- (2018) Gina A. Montealegre Sanchez et al. JOURNAL OF CLINICAL INVESTIGATION
- An open-label trial of JAK 1/2 blockade in progressive IFIH1 -associated neuroinflammation
- (2018) Kavitha Kothur et al. NEUROLOGY
- Endothelial cell functions impaired by interferon in vitro: Insights into the molecular mechanism of thrombotic microangiopathy associated with interferon therapy
- (2018) Haiyan Jia et al. THROMBOSIS RESEARCH
- A transcriptomic atlas of aged human microglia
- (2018) Marta Olah et al. Nature Communications
- Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain
- (2018) Arpiar Saunders et al. CELL
- Microglia have a more extensive and divergent response to interferon-α compared with astrocytes
- (2018) Wen Li et al. GLIA
- Blood-brain barrier breakdown, neuroinflammation, and cognitive decline in older adults
- (2018) Gene L. Bowman et al. Alzheimers & Dementia
- Efficacy of JAK1/2 inhibition in the treatment of chilblain lupus due to TREX1 deficiency
- (2018) Coralie Briand et al. ANNALS OF THE RHEUMATIC DISEASES
- Multiple sclerosis - a review
- (2018) R. Dobson et al. EUROPEAN JOURNAL OF NEUROLOGY
- Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes
- (2018) Timothy R. Hammond et al. IMMUNITY
- JAK 1/2 Blockade in MDA5 Gain-of-Function
- (2018) Kirsty E. McLellan et al. JOURNAL OF CLINICAL IMMUNOLOGY
- STING-mediated type-I interferons contribute to the neuroinflammatory process and detrimental effects following traumatic brain injury
- (2018) Amar Abdullah et al. Journal of Neuroinflammation
- Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis
- (2018) Ana Mendanha Falcão et al. NATURE MEDICINE
- Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral Encephalitis
- (2018) Chintan Chhatbar et al. Cell Reports
- JAK Inhibitors in Rheumatology: Implications for Paediatric Syndromes?
- (2018) S. A. Kerrigan et al. Current Rheumatology Reports
- Interferon-Alpha Reduces Human Hippocampal Neurogenesis and Increases Apoptosis via Activation of Distinct STAT1-Dependent Mechanisms
- (2017) Alessandra Borsini et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Type I interferon-regulated gene expression and signaling in murine mixed glial cells lacking signal transducers and activators of transcription 1 or 2 or interferon regulatory factor 9
- (2017) Wen Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection
- (2017) Brian P. Daniels et al. JOURNAL OF CLINICAL INVESTIGATION
- Detection of interferon alpha protein reveals differential levels and cellular sources in disease
- (2017) Mathieu P. Rodero et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Transcriptomic analysis of purified human cortical microglia reveals age-associated changes
- (2017) Thais F Galatro et al. NATURE NEUROSCIENCE
- JAK inhibition as a therapeutic strategy for immune and inflammatory diseases
- (2017) Daniella M. Schwartz et al. NATURE REVIEWS DRUG DISCOVERY
- Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner
- (2017) Aleksandra Deczkowska et al. Nature Communications
- Trisomy 21 causes changes in the circulating proteome indicative of chronic autoinflammation
- (2017) Kelly D. Sullivan et al. Scientific Reports
- Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution
- (2017) Hansruedi Mathys et al. Cell Reports
- Sifalimumab, an anti-interferon-α monoclonal antibody, in moderate to severe systemic lupus erythematosus: a randomised, double-blind, placebo-controlled study
- (2016) Munther Khamashta et al. ANNALS OF THE RHEUMATIC DISEASES
- Familial chilblain lupus due to a gain-of-function mutation in STING
- (2016) Nadja König et al. ANNALS OF THE RHEUMATIC DISEASES
- Type I interferon causes thrombotic microangiopathy by a dose-dependent toxic effect on the microvasculature
- (2016) D. Kavanagh et al. BLOOD
- Parsing the Interferon Transcriptional Network and Its Disease Associations
- (2016) Sara Mostafavi et al. CELL
- The emerging role of interferon regulatory factor 9 in the antiviral host response and beyond
- (2016) Tamara Suprunenko et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Type-1 interferons contribute to the neuroinflammatory response and disease progression of the MPTP mouse model of Parkinson's disease
- (2016) Bevan S. Main et al. GLIA
- Reduced frontal activation during verbal fluency task in chronic hepatitis C patients with interferon-based therapy as measured by near-infrared spectroscopy
- (2016) Kazumichi Abe et al. HEPATOLOGY RESEARCH
- Brain Endothelial- and Epithelial-Specific Interferon Receptor Chain 1 Drives Virus-Induced Sickness Behavior and Cognitive Impairment
- (2016) Thomas Blank et al. IMMUNITY
- Efficacy of the Janus kinase 1/2 inhibitor ruxolitinib in the treatment of vasculopathy associated with TMEM173 -activating mutations in 3 children
- (2016) Marie-Louise Frémond et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Exploring Autoimmunity in a Cohort of Children with Genetically Confirmed Aicardi–Goutières Syndrome
- (2016) Marco Cattalini et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Type I interferon–mediated monogenic autoinflammation: The type I interferonopathies, a conceptual overview
- (2016) Mathieu P. Rodero et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cerebrospinal fluid interferon alpha levels correlate with neurocognitive impairment in ambulatory HIV-Infected individuals
- (2016) Albert M. Anderson et al. JOURNAL OF NEUROVIROLOGY
- Ageing, neurodegeneration and brain rejuvenation
- (2016) Tony Wyss-Coray NATURE
- Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor
- (2016) Veit Rothhammer et al. NATURE MEDICINE
- Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse
- (2016) Ye Zhang et al. NEURON
- Interferon-β1a modulates glutamate neurotransmission in the CNS through CaMKII and GluN2A-containing NMDA receptors
- (2016) Massimiliano Di Filippo et al. NEUROPHARMACOLOGY
- Neurological Disease as a Failure of Brain–Immune Crosstalk: The Multiple Faces of Neuroinflammation
- (2016) Michal Schwartz et al. TRENDS IN IMMUNOLOGY
- STAT1 Signaling in Astrocytes Is Essential for Control of Infection in the Central Nervous System
- (2016) Shinya Hidano et al. mBio
- Depressive symptoms as a side effect of Interferon-α therapy induced by induction of indoleamine 2,3-dioxygenase 1
- (2016) Yuki Murakami et al. Scientific Reports
- Trisomy 21 consistently activates the interferon response
- (2016) Kelly D Sullivan et al. eLife
- Deletion of the type-1 interferon receptor in APPSWE/PS1ΔE9 mice preserves cognitive function and alters glial phenotype
- (2016) Myles R. Minter et al. Acta Neuropathologica Communications
- Characterization of human disease phenotypes associated with mutations inTREX1,RNASEH2A,RNASEH2B,RNASEH2C,SAMHD1,ADAR, andIFIH1
- (2015) Yanick J. Crow et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Age-related increases in basal ganglia glutamate are associated with TNF, reduced motivation and decreased psychomotor speed during IFN-alpha treatment: Preliminary findings
- (2015) Ebrahim Haroon et al. BRAIN BEHAVIOR AND IMMUNITY
- Inflammatory cytokine-associated depression
- (2015) Francis E. Lotrich BRAIN RESEARCH
- Establishment and Dysfunction of the Blood-Brain Barrier
- (2015) Zhen Zhao et al. CELL
- Lack of Neuronal IFN-β-IFNAR Causes Lewy Body- and Parkinson’s Disease-like Dementia
- (2015) Patrick Ejlerskov et al. CELL
- USP18 lack in microglia causes destructive interferonopathy of the mouse brain
- (2015) T. Goldmann et al. EMBO JOURNAL
- Interferon-α Induces Neurotoxicity Through Activation of the Type I Receptor and the GluN2A Subunit of the NMDA Receptor
- (2015) Cari F. Kessing et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Homeostatic interferon expression in neurons is sufficient for early control of viral infection
- (2015) Sarah E. Cavanaugh et al. JOURNAL OF NEUROIMMUNOLOGY
- Hospital-acquired pneumonia is an independent predictor of poor global outcome in severe traumatic brain injury up to 5 years after discharge
- (2015) Matthew Ryan Kesinger et al. Journal of Trauma and Acute Care Surgery
- Abortively Infected Astrocytes Appear To Represent the Main Source of Interferon Beta in the Virus-Infected Brain
- (2015) Cathleen Pfefferkorn et al. JOURNAL OF VIROLOGY
- Type I interferon dysregulation and neurological disease
- (2015) Sarah McGlasson et al. Nature Reviews Neurology
- Neuroradiologic patterns and novel imaging findings in Aicardi-Goutières syndrome
- (2015) Roberta La Piana et al. NEUROLOGY
- JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
- (2015) Ming Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interferon-λ restricts West Nile virus neuroinvasion by tightening the blood-brain barrier
- (2015) Helen M. Lazear et al. Science Translational Medicine
- Minocycline treatment ameliorates interferon-alpha- induced neurogenic defects and depression-like behaviors in mice
- (2015) Lian-Shun Zheng et al. Frontiers in Cellular Neuroscience
- Hospital-acquired pneumonia is an independent predictor of poor global outcome in severe traumatic brain injury up to 5 years after discharge
- (2015) Matthew Ryan Kesinger et al. Journal of Trauma and Acute Care Surgery
- IFNβ secreted by microglia mediates clearance of myelin debris in CNS autoimmunity
- (2015) Magdalena Kocur et al. Acta Neuropathologica Communications
- Aicardi-Goutières Syndrome Is Caused by IFIH1 Mutations
- (2014) Hirotsugu Oda et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Insights from interferon-α-related depression for the pathogenesis of depression associated with inflammation
- (2014) Carolina Hoyo-Becerra et al. BRAIN BEHAVIOR AND IMMUNITY
- Dynamic structural remodelling of microglia in health and disease: A review of the models, the signals and the mechanisms
- (2014) F. Rohan Walker et al. BRAIN BEHAVIOR AND IMMUNITY
- Protein kinase C activation mediates interferon-β-induced neuronal excitability changes in neocortical pyramidal neurons
- (2014) Olivia Reetz et al. Journal of Neuroinflammation
- An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
- (2014) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- Aging-induced type I interferon response at the choroid plexus negatively affects brain function
- (2014) K. Baruch et al. SCIENCE
- Mechanisms for Interferon-α-Induced Depression and Neural Stem Cell Dysfunction
- (2014) Lian-Shun Zheng et al. Stem Cell Reports
- Chronic exposure of astrocytes to interferon-α reveals molecular changes related to Aicardi–Goutières syndrome
- (2013) Eloy Cuadrado et al. BRAIN
- Type I interferon in neurological disease—The devil from within
- (2013) Markus J. Hofer et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Intracranial calcification in childhood: a review of aetiologies and recognizable phenotypes
- (2013) John H Livingston et al. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
- Down’s syndrome, neuroinflammation, and Alzheimer neuropathogenesis
- (2013) Donna M Wilcock et al. Journal of Neuroinflammation
- Pathology and disease mechanisms in different stages of multiple sclerosis
- (2013) Hans Lassmann JOURNAL OF THE NEUROLOGICAL SCIENCES
- Type-1 interferon signaling mediates neuro-inflammatory events in models of Alzheimer's disease
- (2013) Juliet M. Taylor et al. NEUROBIOLOGY OF AGING
- Aberrant Type I Interferon Regulation in Autoimmunity: Opposite Directions in MS and SLE, Shaped by Evolution and Body Ecology
- (2013) Anthony T. Reder et al. Frontiers in Immunology
- Neuropsychiatric Lupus, the Blood Brain Barrier, and the TWEAK/Fn14 Pathway
- (2013) Ariel D. Stock et al. Frontiers in Immunology
- Jakinibs: a new class of kinase inhibitors in cancer and autoimmune disease
- (2012) Apostolos Kontzias et al. CURRENT OPINION IN PHARMACOLOGY
- Interferon-α (IFNα) neurotoxicity
- (2012) Cari Fritz-French et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Recognizable phenotypes associated with intracranial calcification
- (2012) JOHN H LIVINGSTON et al. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
- Oligodendroglia are limited in type I interferon induction and responsiveness in vivo
- (2012) Parul Kapil et al. GLIA
- Janus-like effects of type I interferon in autoimmune diseases
- (2012) Robert C. Axtell et al. IMMUNOLOGICAL REVIEWS
- The interferons and their receptors-distribution and regulation
- (2012) Nicole A de Weerd et al. IMMUNOLOGY AND CELL BIOLOGY
- Association Between Use of Interferon Beta and Progression of Disability in Patients With Relapsing-Remitting Multiple Sclerosis
- (2012) Afsaneh Shirani et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Anti-IFN- / Receptor Antibody Treatment Ameliorates Disease in Lupus-Predisposed Mice
- (2012) R. Baccala et al. JOURNAL OF IMMUNOLOGY
- Type I interferons impair BDNF-induced cell signaling and neurotrophic activity in differentiated human SH-SY5Y neuroblastoma cells and mouse primary cortical neurons
- (2012) Simona Dedoni et al. JOURNAL OF NEUROCHEMISTRY
- Visualizing Production of Beta Interferon by Astrocytes and Microglia in Brain of La Crosse Virus-Infected Mice
- (2012) C. Kallfass et al. JOURNAL OF VIROLOGY
- Negative Regulation of Human Astrocytes by Interferon (IFN) α in Relation to Growth Inhibition and Impaired Glucose Utilization
- (2012) Ting Wang et al. NEUROCHEMICAL RESEARCH
- Side effects in melanoma patients receiving adjuvant interferon alfa-2b therapy: a nurse’s perspective
- (2012) Krista M. Rubin et al. SUPPORTIVE CARE IN CANCER
- Preserved in vivo response to interferon-alpha in multiple sclerosis patients with neutralising antibodies against interferon-beta (REPAIR study)
- (2012) Melinda Magyari et al. Multiple Sclerosis and Related Disorders
- Interferon modulates central nervous system function
- (2011) Cruz Reyes-Vázquez et al. BRAIN RESEARCH
- Activation of interferon signaling pathways in spinal cord astrocytes from an ALS mouse model
- (2011) Rengang Wang et al. GLIA
- Type I interferon signature is high in lupus and neuromyelitis optica but low in multiple sclerosis
- (2011) Xuan Feng et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Intracerebral large artery disease in Aicardi-Goutières syndrome implicates SAMHD1 in vascular homeostasis
- (2010) VENKATESWARAN RAMESH et al. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
- The Type I Interferon- Mediates a More Severe Neurological Disease in the Absence of the Canonical Signaling Molecule Interferon Regulatory Factor 9
- (2010) M. J. Hofer et al. JOURNAL OF NEUROSCIENCE
- Rates of symptom reporting following traumatic brain injury
- (2010) SUREYYA DIKMEN et al. JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY
- T helper type 1 and 17 cells determine efficacy of interferon-β in multiple sclerosis and experimental encephalomyelitis
- (2010) Robert C Axtell et al. NATURE MEDICINE
- Two phase II trials of temozolomide with interferon-α2b (pegylated and non-pegylated) in patients with recurrent glioblastoma multiforme
- (2009) M D Groves et al. BRITISH JOURNAL OF CANCER
- Fetal Infections and Brain Development
- (2009) James F. Bale CLINICS IN PERINATOLOGY
- Adjuvant Interferon alfa for melanoma: new evidence-based treatment recommendations?
- (2009) Axel Hauschild Current Oncology
- Deficiency of Type I IFN Receptor in Lupus-Prone New Zealand Mixed 2328 Mice Decreases Dendritic Cell Numbers and Activation and Protects from Disease
- (2009) H. Agrawal et al. JOURNAL OF IMMUNOLOGY
- Interferon- Causes Neuronal Dysfunction in Encephalitis
- (2009) A. R. Sas et al. JOURNAL OF NEUROSCIENCE
- Risk for Depression During Interferon-Alpha Treatment Is Affected by the Serotonin Transporter Polymorphism
- (2008) Francis E. Lotrich et al. BIOLOGICAL PSYCHIATRY
- Astrocytes produce interferon-alpha and CXCL10, but not IL-6 or CXCL8, in aicardi-Goutières syndrome
- (2008) Jane T. Van Heteren et al. GLIA
- Type 1 Interferons Cool the Inflamed Brain
- (2008) Robert C. Axtell et al. IMMUNITY
- Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System
- (2008) Marco Prinz et al. IMMUNITY
- Murine Coronavirus Mouse Hepatitis Virus Is Recognized by MDA5 and Induces Type I Interferon in Brain Macrophages/Microglia
- (2008) J. K. Roth-Cross et al. JOURNAL OF VIROLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search