Transcriptomic analysis of purified human cortical microglia reveals age-associated changes

LAG3 (CD223) as a cancer immunotherapy target

(2017) Lawrence P. Andrews et al.   IMMUNOLOGICAL REVIEWS

Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain

(2017) Katharine Askew et al.   Cell Reports

Sall1 is a transcriptional regulator defining microglia identity and function

(2016) Anne Buttgereit et al.   NATURE IMMUNOLOGY

Efficient derivation of microglia-like cells from human pluripotent stem cells

(2016) Julien Muffat et al.   NATURE MEDICINE

Microglial brain region−dependent diversity and selective regional sensitivities to aging

(2016) Kathleen Grabert et al.   NATURE NEUROSCIENCE

Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse

(2016) Ye Zhang et al.   NEURON

Microglia development follows a stepwise program to regulate brain homeostasis

(2016) O. Matcovitch-Natan et al.   SCIENCE

ERAP1-ERAP2 dimers trim MHC I-bound precursor peptides; implications for understanding peptide editing

(2016) Hanna Chen et al.   Scientific Reports

S100A12 Is Part of the Antimicrobial Network against Mycobacterium leprae in Human Macrophages

(2016) Susan Realegeno et al.   PLoS Pathogens

CoRegNet: reconstruction and integrated analysis of co-regulatory networks: Fig. 1.

(2015) Rémy Nicolle et al.   BIOINFORMATICS

Mouse models rarely mimic the transcriptome of human neurodegenerative diseases: A systematic bioinformatics-based critique of preclinical models

(2015) Terry C. Burns et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

CD58/CD2 Is the Primary Costimulatory Pathway in Human CD28−CD8+T Cells

(2015) Judith Leitner et al.   JOURNAL OF IMMUNOLOGY

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Canonical genetic signatures of the adult human brain

(2015) Michael Hawrylycz et al.   NATURE NEUROSCIENCE

Microglia recapitulate a hematopoietic master regulator network in the aging human frontal cortex

(2015) Claudia C. Wehrspaun et al.   NEUROBIOLOGY OF AGING

Organization and Evolution of Brain Lipidome Revealed by Large-Scale Analysis of Human, Chimpanzee, Macaque, and Mouse Tissues

(2015) Katarzyna Bozek et al.   NEURON

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis

(2015) Inge R Holtman et al.   Acta Neuropathologica Communications

DAFS: a data-adaptive flag method for RNA-sequencing data to differentiate genes with low and high expression

(2014) Nysia I George et al.   BMC BIOINFORMATICS

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

(2014) Yonit Lavin et al.   CELL

Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities

(2014) David Gosselin et al.   CELL

Sublime Microglia: Expanding Roles for the Guardians of the CNS

(2014) Michael W. Salter et al.   CELL

Targeting Microglial Activation in Stroke Therapy: Pharmacological Tools and Gender Effects

(2014) Y. Chen et al.   CURRENT MEDICINAL CHEMISTRY

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Microglial priming in neurodegenerative disease

(2014) V. Hugh Perry et al.   Nature Reviews Neurology

A Starring Role for Microglia in Brain Sex Differences

(2014) Kathryn M. Lenz et al.   NEUROSCIENTIST

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

(2014) S. Saeed et al.   SCIENCE

The human side of microglia

(2014) Amy M. Smith et al.   TRENDS IN NEUROSCIENCES

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

(2013) Katrin Kierdorf et al.   NATURE NEUROSCIENCE

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

The microglial sensome revealed by direct RNA sequencing

(2013) Suzanne E Hickman et al.   NATURE NEUROSCIENCE

Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice

(2013) Marie Orre et al.   NEUROBIOLOGY OF AGING

Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta

(2013) Ana Griciuc et al.   NEURON

Functional Impairment of Microglia Coincides with Beta-Amyloid Deposition in Mice with Alzheimer-Like Pathology

(2013) Grietje Krabbe et al.   PLoS One

Innate immune detection of microbial nucleic acids

(2013) Claudia Gürtler et al.   TRENDS IN MICROBIOLOGY

A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model

(2013) Isaac M. Chiu et al.   Cell Reports

RNA-SeQC: RNA-seq metrics for quality control and process optimization

(2012) David S. DeLuca et al.   BIOINFORMATICS

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

(2012) Jeffrey T. Leek et al.   BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Podosomes in migrating microglia: components and matrix degradation

(2012) Catherine Vincent et al.   Journal of Neuroinflammation

Comparative Study of Human and Mouse Postsynaptic Proteomes Finds High Compositional Conservation and Abundance Differences for Key Synaptic Proteins

(2012) Àlex Bayés et al.   PLoS One

Dissecting negative regulation of Toll-like receptor signaling

(2012) Takeshi Kondo et al.   TRENDS IN IMMUNOLOGY

The Fractalkine Receptor but Not CCR2 Is Present on Microglia from Embryonic Development throughout Adulthood

(2011) M. Mizutani et al.   JOURNAL OF IMMUNOLOGY

Combinatorial Transcriptional Control In Blood Stem/Progenitor Cells: Genome-wide Analysis of Ten Major Transcriptional Regulators

(2010) Nicola K. Wilson et al.   Cell Stem Cell

APOBEC3 proteins mediate the clearance of foreign DNA from human cells

(2010) Mark D Stenglein et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

NLR family member NLRC5 is a transcriptional regulator of MHC class I genes

(2010) T. B. Meissner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of Antemortem and Postmortem Variables on Human Brain mRNA Quality: A BrainNet Europe Study

(2009) Pascal F. Durrenberger et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

(2009) Steffen Durinck et al.   Nature Protocols

p204, a p200 family protein, as a multifunctional regulator of cell proliferation and differentiation

(2008) Yi Luan et al.   CYTOKINE & GROWTH FACTOR REVIEWS