Aneuploidy in mammalian oocytes and the impact of maternal ageing

Oocyte mitochondria—key regulators of oocyte function and potential therapeutic targets for improving fertility

(2022) Deepak Adhikari et al.   BIOLOGY OF REPRODUCTION

Women Electing Oocyte Cryopreservation: Characteristics, Information Sources, and Oocyte Disposition: A Systematic Review

(2022) Maria Giannopapa et al.   JOURNAL OF MIDWIFERY & WOMENS HEALTH

Mechanism of spindle pole organization and instability in human oocytes

(2022) Chun So et al.   SCIENCE

Individual-oocyte transcriptomic analysis shows that genotoxic chemotherapy depletes human primordial follicle reserve in vivo by triggering proapoptotic pathways without growth activation

(2021) S. Titus et al.   Scientific Reports

Telomere Length as a Marker of Biological Age: State-of-the-Art, Open Issues, and Future Perspectives

(2021) Alexander Vaiserman et al.   Frontiers in Genetics

Kinetochore individualization in meiosis I is required for centromeric cohesin removal in meiosis II

(2021) Yulia Gryaznova et al.   EMBO JOURNAL

Current Advancements in Noninvasive Profiling of the Embryo Culture Media Secretome

(2021) Raminta Zmuidinaite et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization

(2021) Ci Ji Lim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Two mechanisms drive pronuclear migration in mouse zygotes

(2021) Kathleen Scheffler et al.   Nature Communications

Single human oocyte transcriptome analysis reveals distinct maturation stage‐dependent pathways impacted by age

(2021) Sílvia Llonch et al.   AGING CELL

Parental genome unification is highly error-prone in mammalian embryos

(2021) Tommaso Cavazza et al.   CELL

Myosin-X is dispensable for spindle morphogenesis and positioning in the mouse oocyte

(2021) Flora Crozet et al.   DEVELOPMENT

Mechanisms of Ovarian Aging

(2021) Selena Park et al.   REPRODUCTION

BRCA1 and BRCA2 Tumor Suppressor Function in Meiosis

(2021) Qianyan Li et al.   Frontiers in Cell and Developmental Biology

Mitochondria: Their relevance during oocyte ageing

(2021) Jiska van der Reest et al.   AGEING RESEARCH REVIEWS

Ovulation suppression protects against chromosomal abnormalities in mouse eggs at advanced maternal age

(2021) Emmanouella E. Chatzidaki et al.   CURRENT BIOLOGY

Distinct classes of lagging chromosome underpin age-related oocyte aneuploidy in mouse

(2021) Aleksandar I. Mihajlović et al.   DEVELOPMENTAL CELL

Separase cleaves the kinetochore protein Meikin at the meiosis I/II transition

(2021) Nolan K. Maier et al.   DEVELOPMENTAL CELL

Genetic insights into biological mechanisms governing human ovarian ageing

(2021) Katherine S. Ruth et al.   NATURE

Loss of sister kinetochore co-orientation and peri-centromeric cohesin protection after meiosis I depends on cleavage of centromeric REC8

(2021) Sugako Ogushi et al.   DEVELOPMENTAL CELL

Implications of environmental toxicants on ovarian follicles: how it can adversely affect the female fertility?

(2021) Keerthi Priya et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Update about the disrupting‐effects of phthalates on the human reproductive system

(2021) Inês Mesquita et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Interplay between chromatin marks in development and disease

(2021) Sanne M. Janssen et al.   NATURE REVIEWS GENETICS

Single-cell analysis of human ovarian cortex identifies distinct cell populations but no oogonial stem cells

(2020) Magdalena Wagner et al.   Nature Communications

A PP2A-B56—Centered View on Metaphase-to-Anaphase Transition in Mouse Oocyte Meiosis I

(2020) Leonor Keating et al.   Cells

Human oocytes harboring damaged DNA can complete meiosis I

(2020) Gaudeline Rémillard-Labrosse et al.   FERTILITY AND STERILITY

Mathematical modeling of human oocyte aneuploidy

(2020) Katarzyna M. Tyc et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oocytes can efficiently repair DNA double-strand breaks to restore genetic integrity and protect offspring health

(2020) Jessica M. Stringer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms underlying disruption of oocyte spindle stability by bisphenol compounds

(2020) Luhan Yang et al.   REPRODUCTION

Artificially decreasing cortical tension generates aneuploidy in mouse oocytes

(2020) Isma Bennabi et al.   Nature Communications

Oxidative Stress and BPA Toxicity: An Antioxidant Approach for Male and Female Reproductive Dysfunction

(2020) Rosaria Meli et al.   Antioxidants

SnapShot: Meiosis – Prophase I

(2020) Laura Láscarez-Lagunas et al.   CELL

Insights into variation in meiosis from 31,228 human sperm genomes

(2020) Avery Davis Bell et al.   NATURE

Decreased expression of TERT and telomeric proteins as human ovaries age may cause telomere shortening

(2020) Fatma Uysal et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Oxidative Stress in Reproduction: A Mitochondrial Perspective

(2020) Alexandra Almansa-Ordonez et al.   Biology-Basel

Increased transcriptome variation and localised DNA methylation changes in oocytes from aged mice revealed by parallel single‐cell analysis

(2020) Juan Castillo‐Fernandez et al.   AGING CELL

Mitochondria-targeted therapeutics, MitoQ and BGP-15, reverse aging-associated meiotic spindle defects in mouse and human oocytes

(2020) Usama Al-Zubaidi et al.   HUMAN REPRODUCTION

Role of maternal age and pregnancy history in risk of miscarriage: prospective register based study

(2019) Maria C Magnus et al.   BMJ-British Medical Journal

Telomeres and telomerase: three decades of progress

(2019) Jerry W. Shay et al.   NATURE REVIEWS GENETICS

Aneuploidy in Oocytes Is Prevented by Sustained CDK1 Activity through Degron Masking in Cyclin B1

(2019) Mark D. Levasseur et al.   DEVELOPMENTAL CELL

Maternal obesity enhances oocyte chromosome abnormalities associated with aging

(2019) Yan Yun et al.   CHROMOSOMA

Post‐metaphase correction of aberrant kinetochore‐microtubule attachments in mammalian eggs

(2019) Anna Kouznetsova et al.   EMBO REPORTS

A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes

(2019) Chun So et al.   SCIENCE

Chromosome errors in human eggs shape natural fertility over reproductive life span

(2019) Jennifer R. Gruhn et al.   SCIENCE

Single-Cell Transcriptome Analysis of Uniparental Embryos Reveals Parent-of-Origin Effects on Human Preimplantation Development

(2019) Lizhi Leng et al.   Cell Stem Cell

Meiotic Kinetochores Fragment into Multiple Lobes upon Cohesin Loss in Aging Eggs

(2019) Agata P. Zielinska et al.   CURRENT BIOLOGY

Actin-microtubule interplay coordinates spindle assembly in human oocytes

(2019) Johannes Roeles et al.   Nature Communications

Cohesin cleavage by separase is enhanced by a substrate motif distinct from the cleavage site

(2019) Laura E. Rosen et al.   Nature Communications

Tension-Induced Error Correction and Not Kinetochore Attachment Status Activates the SAC in an Aurora-B/C-Dependent Manner in Oocytes

(2018) Antoine Vallot et al.   CURRENT BIOLOGY

Spindle abnormalities and chromosome misalignment in bovine oocytes after exposure to low doses of bisphenol A or bisphenol S

(2018) Kelly A Campen et al.   HUMAN REPRODUCTION

The importance of DNA repair for maintaining oocyte quality in response to anti-cancer treatments, environmental toxins and maternal ageing

(2018) Amy L Winship et al.   HUMAN REPRODUCTION UPDATE

Progress in mitochondrial replacement therapies

(2018) Mary Herbert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Evaluation of a novel non-invasive preimplantation genetic screening approach

(2018) Valeriy Kuznyetsov et al.   PLoS One

Resveratrol reverses the adverse effects of a diet-induced obese murine model on oocyte quality and zona pellucida softening

(2018) Zhenzhen Jia et al.   Food & Function

Replacement Bisphenols Adversely Affect Mouse Gametogenesis with Consequences for Subsequent Generations

(2018) Tegan S. Horan et al.   CURRENT BIOLOGY

Chromatin analysis in human early development reveals epigenetic transition during ZGA

(2018) Jingyi Wu et al.   NATURE

Generation of human oogonia from induced pluripotent stem cells in vitro

(2018) Chika Yamashiro et al.   SCIENCE

Dual-spindle formation in zygotes keeps parental genomes apart in early mammalian embryos

(2018) Judith Reichmann et al.   SCIENCE

Separation and Loss of Centrioles From Primordidal Germ Cells To Mature Oocytes In The Mouse

(2018) Calvin Simerly et al.   Scientific Reports

Ovulation: Parallels with Inflammatory Processes

(2018) Diane M Duffy et al.   ENDOCRINE REVIEWS

Mechanisms regulating zygotic genome activation

(2018) Katharine N. Schulz et al.   NATURE REVIEWS GENETICS

Tri-directional anaphases as a novel chromosome segregation defect in human oocytes

(2017) Jenna Haverfield et al.   HUMAN REPRODUCTION

The age of fathers in the USA is rising: an analysis of 168 867 480 births from 1972 to 2015

(2017) Yash S. Khandwala et al.   HUMAN REPRODUCTION

Chromosome biorientation and APC activity remain uncoupled in oocytes with reduced volume

(2017) Simon I.R. Lane et al.   JOURNAL OF CELL BIOLOGY

Molecular mechanisms of kinesin-14 motors in spindle assembly and chromosome segregation

(2017) Zhen-Yu She et al.   JOURNAL OF CELL SCIENCE

Genetic details of controversial 'three-parent baby' revealed

(2017) Sara Reardon   NATURE

Actin protects mammalian eggs against chromosome segregation errors

(2017) Binyam Mogessie et al.   SCIENCE

Loss of Centromere Cohesion in Aneuploid Human Oocytes Correlates with Decreased Kinetochore Localization of the Sac Proteins Bub1 and Bubr1

(2017) Julie Lagirand-Cantaloube et al.   Scientific Reports

Moving and stopping: Regulation of chromosome movement to promote meiotic chromosome pairing and synapsis

(2017) Benjamin Alleva et al.   Nucleus

Moving and stopping: Regulation of chromosome movement to promote meiotic chromosome pairing and synapsis

(2017) Benjamin Alleva et al.   Nucleus

Bisphenol S negatively affects the meotic maturation of pig oocytes

(2017) Tereza Žalmanová et al.   Scientific Reports

Chromosome Cohesion Established by Rec8-Cohesin in Fetal Oocytes Is Maintained without Detectable Turnover in Oocytes Arrested for Months in Mice

(2016) Sabrina Burkhardt et al.   CURRENT BIOLOGY

Cell Size Determines the Strength of the Spindle Assembly Checkpoint during Embryonic Development

(2016) Matilde Galli et al.   DEVELOPMENTAL CELL

Proof of concept: preimplantation genetic screening without embryo biopsy through analysis of cell-free DNA in spent embryo culture media

(2016) Mousa I. Shamonki et al.   FERTILITY AND STERILITY

Chemotherapy-induced damage to ovary: mechanisms and clinical impact

(2016) Giuliano Bedoschi et al.   Future Oncology

Obesity-induced oocyte mitochondrial defects are partially prevented and rescued by supplementation with co-enzyme Q10 in a mouse model

(2016) C.E. Boots et al.   HUMAN REPRODUCTION

Building a Regulatory Network with Short Linear Sequence Motifs: Lessons from the Degrons of the Anaphase-Promoting Complex

(2016) Norman E. Davey et al.   MOLECULAR CELL

Reconstitution in vitro of the entire cycle of the mouse female germ line

(2016) Orie Hikabe et al.   NATURE

Specification and epigenetic programming of the human germ line

(2016) Walfred W. C. Tang et al.   NATURE REVIEWS GENETICS

Noninvasive chromosome screening of human embryos by genome sequencing of embryo culture medium for in vitro fertilization

(2016) Juanjuan Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes

(2016) Liam P. Cheeseman et al.   Nature Communications

F-actin mechanics control spindle centring in the mouse zygote

(2016) Agathe Chaigne et al.   Nature Communications

Human oocyte developmental potential is predicted by mechanical properties within hours after fertilization

(2016) Livia Z. Yanez et al.   Nature Communications

The Impact of Biopsy on Human Embryo Developmental Potential during Preimplantation Genetic Diagnosis

(2016) Danilo Cimadomo et al.   Biomed Research International

Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging

(2015) Assaf Ben-Meir et al.   AGING CELL

The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics

(2015) Andrea Musacchio   CURRENT BIOLOGY

Blastocoel fluid from differentiated blastocysts harbors embryonic genomic material capable of a whole-genome deoxyribonucleic acid amplification and comprehensive chromosome microarray analysis

(2015) Kyle J. Tobler et al.   FERTILITY AND STERILITY

Genome-wide maps of recombination and chromosome segregation in human oocytes and embryos show selection for maternal recombination rates

(2015) Christian S Ottolini et al.   NATURE GENETICS

Adult human and mouse ovaries lack DDX4-expressing functional oogonial stem cells

(2015) Hua Zhang et al.   NATURE MEDICINE

Aging alters histone H3 lysine 4 methylation in mouse germinal vesicle stage oocytes

(2015) Gen-Bao Shao et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Error-prone chromosome-mediated spindle assembly favors chromosome segregation defects in human oocytes

(2015) Z. Holubcova et al.   SCIENCE

DNA damage-induced metaphase I arrest is mediated by the spindle assembly checkpoint and maternal age

(2015) Petros Marangos et al.   Nature Communications

A narrow window of cortical tension guides asymmetric spindle positioning in the mouse oocyte

(2015) A. Chaigne et al.   Nature Communications

Bivalent separation into univalents precedes age-related meiosis I errors in oocytes

(2015) Yogo Sakakibara et al.   Nature Communications

Sister kinetochore splitting and precocious disintegration of bivalents could explain the maternal age effect

(2015) Agata P Zielinska et al.   eLife

Unique geometry of sister kinetochores in human oocytes during meiosis I may explain maternal age-associated increases in chromosomal abnormalities

(2015) Jessica Patel et al.   Biology Open

Nuclear Pores Protect Genome Integrity by Assembling a Premitotic and Mad1-Dependent Anaphase Inhibitor

(2014) Veronica Rodriguez-Bravo et al.   CELL

Shugoshins: Tension-Sensitive Pericentromeric Adaptors Safeguarding Chromosome Segregation

(2014) Adele L. Marston   MOLECULAR AND CELLULAR BIOLOGY

Meikin is a conserved regulator of meiosis-I-specific kinetochore function

(2014) Jihye Kim et al.   NATURE

Single cell sequencing reveals low levels of aneuploidy across mammalian tissues

(2014) Kristin A. Knouse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversal of Female Infertility by Chk2 Ablation Reveals the Oocyte DNA Damage Checkpoint Pathway

(2014) E. Bolcun-Filas et al.   SCIENCE

Genome Analyses of Single Human Oocytes

(2013) Yu Hou et al.   CELL

Premature dyad separation in meiosis II is the major segregation error with maternal age in mouse oocytes

(2013) Y. Yun et al.   DEVELOPMENT

The nature of aneuploidy with increasing age of the female partner: a review of 15,169 consecutive trophectoderm biopsies evaluated with comprehensive chromosomal screening

(2013) Jason M. Franasiak et al.   FERTILITY AND STERILITY

Resveratrol protects against age-associated infertility in mice

(2013) Mengyuan Liu et al.   HUMAN REPRODUCTION

Bisphenol-A and human oocyte maturation in vitro

(2013) Ronit Machtinger et al.   HUMAN REPRODUCTION

Measurement of ATP in Single Oocytes: Impact of Maturation and Cumulus Cells on Levels and Consumption

(2013) Caroline M. Dalton et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing

(2013) Zhigang Xue et al.   NATURE

Vesicles modulate an actin network for asymmetric spindle positioning

(2013) Zuzana Holubcová et al.   NATURE CELL BIOLOGY

A soft cortex is essential for asymmetric spindle positioning in mouse oocytes

(2013) Agathe Chaigne et al.   NATURE CELL BIOLOGY

The road to maturation: somatic cell interaction and self-organization of the mammalian oocyte

(2013) Rong Li et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Age-Associated Metabolic and Morphologic Changes in Mitochondria of Individual Mouse and Hamster Oocytes

(2013) Fatma Simsek-Duran et al.   PLoS One

Female mice lack adult germ-line stem cells but sustain oogenesis using stable primordial follicles

(2013) L. Lei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-associated telomere shortening in mouse oocytes

(2013) Tomoko Yamada-Fukunaga et al.   Reproductive Biology and Endocrinology

Genomic DNA in human blastocoele fluid

(2013) S. Palini et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Chromosome cohesion decreases in human eggs with advanced maternal age

(2012) Francesca E. Duncan et al.   AGING CELL

Genome-wide Single-Cell Analysis of Recombination Activity and De Novo Mutation Rates in Human Sperm

(2012) Jianbin Wang et al.   CELL

Lack of response to unaligned chromosomes in mammalian female gametes

(2012) Jaroslava Sebestova et al.   CELL CYCLE

Timing of anaphase-promoting complex activation in mouse oocytes is predicted by microtubule-kinetochore attachment but not by bivalent alignment or tension

(2012) S. I. R. Lane et al.   DEVELOPMENT

Age-related aneuploidy through cohesion exhaustion

(2012) Rolf Jessberger   EMBO REPORTS

Abnormal DNA methylation in oocytes could be associated with a decrease in reproductive potential in old mice

(2012) Ming-xing Yue et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Ceramide and its transport protein (CERT) contribute to deterioration of mitochondrial structure and function in aging oocytes

(2012) Loro L. Kujjo et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Oocyte formation by mitotically active germ cells purified from ovaries of reproductive-age women

(2012) Yvonne A R White et al.   NATURE MEDICINE

Human aneuploidy: mechanisms and new insights into an age-old problem

(2012) So I. Nagaoka et al.   NATURE REVIEWS GENETICS

Geometry and force behind kinetochore orientation: lessons from meiosis

(2012) Yoshinori Watanabe   NATURE REVIEWS MOLECULAR CELL BIOLOGY

High Fat Diet Induced Developmental Defects in the Mouse: Oocyte Meiotic Aneuploidy and Fetal Growth Retardation/Brain Defects

(2012) Kerri M. Luzzo et al.   PLoS One

Error-prone mammalian female meiosis from silencing the spindle assembly checkpoint without normal interkinetochore tension

(2012) A. Kolano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bisphenol A alters early oogenesis and follicle formation in the fetal ovary of the rhesus monkey

(2012) P. A. Hunt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probing Meiotic Recombination and Aneuploidy of Single Sperm Cells by Whole-Genome Sequencing

(2012) S. Lu et al.   SCIENCE

Age-Dependent Susceptibility of Chromosome Cohesion to Premature Separase Activation in Mouse Oocytes1

(2011) Teresa Chiang et al.   BIOLOGY OF REPRODUCTION

Effect of Aging on Superovulation Efficiency, Aneuploidy Rates, and Sister Chromatid Cohesion in Mice Aged Up to 15 Months1

(2011) Julie A. Merriman et al.   BIOLOGY OF REPRODUCTION

Complete Kinetochore Tracking Reveals Error-Prone Homologous Chromosome Biorientation in Mammalian Oocytes

(2011) Tomoya S. Kitajima et al.   CELL

Spire-Type Actin Nucleators Cooperate with Formin-2 to Drive Asymmetric Oocyte Division

(2011) Sybille Pfender et al.   CURRENT BIOLOGY

The Role of Shugoshin in Meiotic Chromosome Segregation

(2011) D. Clift et al.   CYTOGENETIC AND GENOME RESEARCH

Aneuploidy in Human Spermatozoa

(2011) C. Templado et al.   CYTOGENETIC AND GENOME RESEARCH

Structural basis of cargo recognition by the myosin-X MyTH4-FERM domain

(2011) Yoshinori Hirano et al.   EMBO JOURNAL

Evidence that carbonyl stress by methylglyoxal exposure induces DNA damage and spindle aberrations, affects mitochondrial integrity in mammalian oocytes and contributes to oocyte ageing

(2011) Carla Tatone et al.   HUMAN REPRODUCTION

Defective deacetylation of histone 4 K12 in human oocytes is associated with advanced maternal age and chromosome misalignment

(2011) I.M. van den Berg et al.   HUMAN REPRODUCTION

An actin-dependent mechanism for long-range vesicle transport

(2011) Melina Schuh   NATURE CELL BIOLOGY

Chromosome missegregation in human cells arises through specific types of kinetochore-microtubule attachment errors

(2011) S. L. Thompson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prevention of maternal aging-associated oocyte aneuploidy and meiotic spindle defects in mice by dietary and genetic strategies

(2011) K. Selesniemi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Minimal Midzone Protein Module Controls Formation and Length of Antiparallel Microtubule Overlaps

(2010) Peter Bieling et al.   CELL

Evidence that Weakened Centromere Cohesion Is a Leading Cause of Age-Related Aneuploidy in Oocytes

(2010) Teresa Chiang et al.   CURRENT BIOLOGY

Age-Related Meiotic Segregation Errors in Mammalian Oocytes Are Preceded by Depletion of Cohesin and Sgo2

(2010) Lisa Martine Lister et al.   CURRENT BIOLOGY

Effect of oxidative stress during repeated ovulation on the structure and functions of the ovary, oocytes, and their mitochondria

(2010) Kaori Miyamoto et al.   FREE RADICAL BIOLOGY AND MEDICINE

Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytes

(2010) K. Tachibana-Konwalski et al.   GENES & DEVELOPMENT

Overweight and obesity negatively affect the outcomes of ovarian stimulation andin vitrofertilisation: a cohort study of 2628 Chinese women

(2010) Dan Zhang et al.   GYNECOLOGICAL ENDOCRINOLOGY

Cortical Mechanics and Meiosis II Completion in Mammalian Oocytes Are Mediated by Myosin-II and Ezrin-Radixin-Moesin (ERM) Proteins

(2010) Stephanie M. Larson et al.   MOLECULAR BIOLOGY OF THE CELL

Maternal Diet-Induced Obesity Alters Mitochondrial Activity and Redox Status in Mouse Oocytes and Zygotes

(2010) Natalia Igosheva et al.   PLoS One

Defective cohesin is associated with age-dependent misaligned chromosomes in oocytes

(2010) Lin Liu et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Polar body biopsy: a viable alternative to preimplantation genetic diagnosis and screening

(2010) M Montag et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Paternal contribution to aneuploidy in preimplantation embryos

(2010) MC Magli et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Aging changes the chromatin configuration and histone methylation of mouse oocytes at germinal vesicle stage

(2010) I. Manosalva et al.   THERIOGENOLOGY

Aging Alters Histone H4 Acetylation and CDC2A in Mouse Germinal Vesicle Stage Oocytes1

(2009) Iris Manosalva et al.   BIOLOGY OF REPRODUCTION

A New Model for Asymmetric Spindle Positioning in Mouse Oocytes

(2008) Melina Schuh et al.   CURRENT BIOLOGY

Spindle Positioning in Mouse Oocytes Relies on a Dynamic Meshwork of Actin Filaments

(2008) Jessica Azoury et al.   CURRENT BIOLOGY

Age-associated increase in aneuploidy and changes in gene expression in mouse eggs

(2008) Hua Pan et al.   DEVELOPMENTAL BIOLOGY

Evaluation of aneugenic effects of bisphenol A in somatic and germ cells of the mouse

(2008) F. Pacchierotti et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The cohesin ring concatenates sister DNA molecules

(2008) Christian H. Haering et al.   NATURE

Spatial and temporal coordination of mitosis by Ran GTPase

(2008) Paul R. Clarke et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Meiotic Regulation of TPX2 Protein Levels Governs Cell Cycle Progression in Mouse Oocytes

(2008) Stéphane Brunet et al.   PLoS One

Effect of bisphenol A on steroid hormone production in rat ovarian theca-interstitial and granulosa cells

(2007) Wei Zhou et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY