Chromosome errors in human eggs shape natural fertility over reproductive life span

SureTypeSC - A Random Forest and Gaussian Mixture predictor of high confidence genotypes in single cell data

(2019) Ivan Vogel et al.   BIOINFORMATICS

Outcome of immature oocytes collection of 119 cancer patients during ovarian tissue harvesting for fertility preservation

(2018) Alon Kedem et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Human female meiosis revised: new insights into the mechanisms of chromosome segregation and aneuploidies from advanced genomics and time-lapse imaging

(2017) Antonio Capalbo et al.   HUMAN REPRODUCTION UPDATE

Loss of Centromere Cohesion in Aneuploid Human Oocytes Correlates with Decreased Kinetochore Localization of the Sac Proteins Bub1 and Bubr1

(2017) Julie Lagirand-Cantaloube et al.   Scientific Reports

Tripolar mitosis and partitioning of the genome arrests human preimplantation development in vitro

(2017) Christian S. Ottolini et al.   Scientific Reports

The ASA's Statement onp-Values: Context, Process, and Purpose

(2016) Ronald L. Wasserstein et al.   AMERICAN STATISTICIAN

Artificial oocyte activation with calcium ionophore does not cause a widespread increase in chromosome segregation errors in the second meiotic division of the oocyte

(2016) Antonio Capalbo et al.   FERTILITY AND STERILITY

Generation of meiomaps of genome-wide recombination and chromosome segregation in human oocytes

(2016) Christian S Ottolini et al.   Nature Protocols

Developmental evidence for obstetric adaptation of the human female pelvis

(2016) Alik Huseynov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Live birth following in vitro maturation of oocytes retrieved from extracorporeal ovarian tissue aspiration and embryo cryopreservation for 5 years

(2015) Peter S. Uzelac et al.   FERTILITY AND STERILITY

Reduction of multiple pregnancies in the advanced maternal age population after implementation of an elective single embryo transfer policy coupled with enhanced embryo selection: pre- and post-intervention study

(2015) Filippo Maria Ubaldi et al.   HUMAN REPRODUCTION

In vitro maturation (IVM) of oocytes recovered from ovariectomy specimens in the laboratory: a promising “ex vivo” method of oocyte cryopreservation resulting in the first report of an ongoing pregnancy in Europe

(2015) Ingrid Segers et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Success and challenges in fertility preservation after ovarian tissue grafting

(2015) Claus Yding Andersen   LANCET

Genome-wide maps of recombination and chromosome segregation in human oocytes and embryos show selection for maternal recombination rates

(2015) Christian S Ottolini et al.   NATURE GENETICS

Common variants spanning PLK4 are associated with mitotic-origin aneuploidy in human embryos

(2015) R. C. McCoy et al.   SCIENCE

Evidence of Selection against Complex Mitotic-Origin Aneuploidy during Preimplantation Development

(2015) Rajiv C. McCoy et al.   PLoS Genetics

Sister kinetochore splitting and precocious disintegration of bivalents could explain the maternal age effect

(2015) Agata P Zielinska et al.   eLife

Unique geometry of sister kinetochores in human oocytes during meiosis I may explain maternal age-associated increases in chromosomal abnormalities

(2015) Jessica Patel et al.   Biology Open

Alternative meiotic chromatid segregation in the holocentric plant Luzula elegans

(2014) Stefan Heckmann et al.   Nature Communications

Behavior of Aberrant Chromosome Configurations in Drosophila melanogaster Female Meiosis I

(2014) William D. Gilliland et al.   G3-Genes Genomes Genetics

First pregnancy and live birth resulting from cryopreserved embryos obtained from in vitro matured oocytes after oophorectomy in an ovarian cancer patient

(2013) E. B. Prasath et al.   HUMAN REPRODUCTION

Chromosome cohesion decreases in human eggs with advanced maternal age

(2012) Francesca E. Duncan et al.   AGING CELL

Age-related aneuploidy through cohesion exhaustion

(2012) Rolf Jessberger   EMBO REPORTS

The dynamics of in vitro maturation of germinal vesicle oocytes

(2012) Laura Escrich et al.   FERTILITY AND STERILITY

Increased longevity evolves from grandmothering

(2012) P. S. Kim et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Do women stop early? Similarities in fertility decline in humans and chimpanzees

(2010) Kristen Hawkes et al.   Annals of the New York Academy of Sciences

Evidence that Weakened Centromere Cohesion Is a Leading Cause of Age-Related Aneuploidy in Oocytes

(2010) Teresa Chiang et al.   CURRENT BIOLOGY

Age-Related Meiotic Segregation Errors in Mammalian Oocytes Are Preceded by Depletion of Cohesin and Sgo2

(2010) Lisa Martine Lister et al.   CURRENT BIOLOGY

Spontaneous in vitro maturation and artificial activation of human germinal vesicle oocytes recovered from stimulated cycles

(2010) Laura Escrich et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Embryo development of fresh 'versus' vitrified metaphase II oocytes after ICSI: a prospective randomized sibling-oocyte study

(2009) L. Rienzi et al.   HUMAN REPRODUCTION