Cohesin cleavage by separase is enhanced by a substrate motif distinct from the cleavage site
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Title
Cohesin cleavage by separase is enhanced by a substrate motif distinct from the cleavage site
Authors
Keywords
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Journal
Nature Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-11-15
DOI
10.1038/s41467-019-13209-y
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Note: Only part of the references are listed.- Structural biology of the separase–securin complex with crucial roles in chromosome segregation
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- Structural basis of cohesin cleavage by separase
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- Human Chromosome Segregation Involves Multi-Layered Regulation of Separase by the Peptidyl-Prolyl-Isomerase Pin1
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- PP2A delays APC/C-dependent degradation of separase-associated but not free securin
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- Identifi cation of protease exosite-interacting peptides that enhance substrate cleavage kinetics
- (2012) Abeer M. Jabaiah et al. BIOLOGICAL CHEMISTRY
- Separase Sensor Reveals Dual Roles for Separase Coordinating Cohesin Cleavage and Cdk1 Inhibition
- (2012) Norihisa Shindo et al. DEVELOPMENTAL CELL
- RELION: Implementation of a Bayesian approach to cryo-EM structure determination
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- Cohesin: Its Roles and Mechanisms
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- Separase Is Recruited to Mitotic Chromosomes to Dissolve Sister Chromatid Cohesion in a DNA-Dependent Manner
- (2009) Yuxiao Sun et al. CELL
- Role of cleavage by separase of the Rec8 kleisin subunit of cohesin during mammalian meiosis I
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- Structural and Dynamic Characterization of Intrinsically Disordered Human Securin by NMR Spectroscopy
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