Shugoshins: Tension-Sensitive Pericentromeric Adaptors Safeguarding Chromosome Segregation

Structure and function of cohesin's Scc3/SA regulatory subunit

(2014) Maurici B. Roig et al.   FEBS LETTERS

Tension-dependent removal of pericentromeric shugoshin is an indicator of sister chromosome biorientation

(2014) O. O. Nerusheva et al.   GENES & DEVELOPMENT

Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint

(2014) N. London et al.   GENES & DEVELOPMENT

Chromosome Segregation in Budding Yeast: Sister Chromatid Cohesion and Related Mechanisms

(2014) Adele L. Marston   GENETICS

Sgo1 recruits PP2A to chromosomes to ensure sister chromatid bi-orientation during mitosis

(2014) H. D. Eshleman et al.   JOURNAL OF CELL SCIENCE

Mutations in SGOL1 cause a novel cohesinopathy affecting heart and gut rhythm

(2014) Philippe Chetaille et al.   NATURE GENETICS

Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion

(2014) Kodai Hara et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SHUGOSHINs and PATRONUS protect meiotic centromere cohesion inArabidopsis thaliana

(2014) Linda Zamariola et al.   PLANT JOURNAL

Regulation of Centromere Localization of the Drosophila Shugoshin MEI-S332 and Sister-Chromatid Cohesion in Meiosis

(2014) Cristina Nogueira et al.   G3-Genes Genomes Genetics

Sgo1 Regulates Both Condensin and Ipl1/Aurora B to Promote Chromosome Biorientation

(2014) Karolina Peplowska et al.   PLoS Genetics

Selective Disruption of Aurora C Kinase Reveals Distinct Functions from Aurora B Kinase during Meiosis in Mouse Oocytes

(2014) Ahmed Z. Balboula et al.   PLoS Genetics

Shugoshin biases chromosomes for biorientation through condensin recruitment to the pericentromere

(2014) Kitty F Verzijlbergen et al.   eLife

Making an effective switch at the kinetochore by phosphorylation and dephosphorylation

(2013) Hironori Funabiki et al.   CHROMOSOMA

Cohesin-Dependent Association of Scc2/4 with the Centromere Initiates Pericentromeric Cohesion Establishment

(2013) Josefin Fernius et al.   CURRENT BIOLOGY

Phospho-H2A and Cohesin Specify Distinct Tension-Regulated Sgo1 Pools at Kinetochores and Inner Centromeres

(2013) Hong Liu et al.   CURRENT BIOLOGY

Centromeric Cohesion Is Protected Twice at Meiosis, by SHUGOSHINs at Anaphase I and by PATRONUS at Interkinesis

(2013) Laurence Cromer et al.   CURRENT BIOLOGY

The PP2A Inhibitor I2PP2A Is Essential for Sister Chromatid Segregation in Oocyte Meiosis II

(2013) Jean-Philippe Chambon et al.   CURRENT BIOLOGY

Suv4-20h2 mediates chromatin compaction and is important for cohesin recruitment to heterochromatin

(2013) M. Hahn et al.   GENES & DEVELOPMENT

Kinetochore Function and Chromosome Segregation Rely on Critical Residues in Histones H3 and H4 in Budding Yeast

(2013) Tessie M. Ng et al.   GENETICS

Frameshift mutations of chromosome cohesion–related genes SGOL1 and PDS5B in gastric and colorectal cancers with high microsatellite instability

(2013) Min Sung Kim et al.   HUMAN PATHOLOGY

Tension sensing by Aurora B kinase is independent of survivin-based centromere localization

(2013) Christopher S. Campbell et al.   NATURE

Polo kinase Cdc5 is a central regulator of meiosis I

(2013) M. A. Attner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The signaling network that silences the spindle assembly checkpoint upon the establishment of chromosome bipolar attachment

(2013) F. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aurora B and Cdk1 mediate Wapl activation and release of acetylated cohesin from chromosomes by phosphorylating Sororin

(2013) T. Nishiyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pds5 promotes and protects cohesin acetylation

(2013) K.-L. Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tracking spindle checkpoint signals from kinetochores to APC/C

(2013) Luying Jia et al.   TRENDS IN BIOCHEMICAL SCIENCES

Bod1 regulates protein phosphatase 2A at mitotic kinetochores

(2013) Iain M. Porter et al.   Nature Communications

Sgol2 provides a regulatory platform that coordinates essential cell cycle processes during meiosis I in oocytes

(2013) Ahmed Rattani et al.   eLife

Cohesin’s DNA Exit Gate Is Distinct from Its Entrance Gate and Is Regulated by Acetylation

(2012) Kok-Lung Chan et al.   CELL

Haploinsufficiency ofSGO1results in deregulated centrosome dynamics, enhanced chromosomal instability and colon tumorigenesis

(2012) Hiroshi Y. Yamada et al.   CELL CYCLE

Bub1 Kinase and Sgo1 Modulate Pericentric Chromatin in Response to Altered Microtubule Dynamics

(2012) Julian Haase et al.   CURRENT BIOLOGY

Separase Biosensor Reveals that Cohesin Cleavage Timing Depends on Phosphatase PP2ACdc55 Regulation

(2012) Gilad Yaakov et al.   DEVELOPMENTAL CELL

Xenopus Shugoshin 2 regulates the spindle assembly pathway mediated by the chromosomal passenger complex

(2012) Teresa Rivera et al.   EMBO JOURNAL

Mps1 promotes rapid centromere accumulation of Aurora B

(2012) Maike S van der Waal et al.   EMBO REPORTS

Phosphorylation-enabled binding of SGO1–PP2A to cohesin protects sororin and centromeric cohesion during mitosis

(2012) Hong Liu et al.   NATURE CELL BIOLOGY

The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis

(2012) Mar Carmena et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore

(2012) Emily A. Foley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Shugoshins: from protectors of cohesion to versatile adaptors at the centromere

(2012) Cristina Gutiérrez-Caballero et al.   TRENDS IN GENETICS

Cyclin A2 Is Required for Sister Chromatid Segregation, But Not Separase Control, in Mouse Oocyte Meiosis

(2012) Sandra A. Touati et al.   Cell Reports

Meiosis I chromosome segregation is established through regulation of microtubule–kinetochore interactions

(2012) Matthew P Miller et al.   eLife

Global analysis of core histones reveals nucleosomal surfaces required for chromosome bi-orientation

(2011) Satoshi Kawashima et al.   EMBO JOURNAL

Shugoshin is a Mad1/Cdc20-like interactor of Mad2

(2011) Michael Orth et al.   EMBO JOURNAL

Cohesin, condensin, and the intramolecular centromere loop together generate the mitotic chromatin spring

(2011) Andrew D. Stephens et al.   JOURNAL OF CELL BIOLOGY

Regulation of sororin by Cdk1-mediated phosphorylation

(2011) Megan R. Dreier et al.   JOURNAL OF CELL SCIENCE

Bub1, Sgo1, and Mps1 mediate a distinct pathway for chromosome biorientation in budding yeast

(2011) Zuzana Storchová et al.   MOLECULAR BIOLOGY OF THE CELL

Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells

(2011) Jungseog Kang et al.   MOLECULAR BIOLOGY OF THE CELL

Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase

(2011) Emily A. Foley et al.   NATURE CELL BIOLOGY

OsSGO1 maintains synaptonemal complex stabilization in addition to protecting centromeric cohesion during rice meiosis

(2011) Mo Wang et al.   PLANT JOURNAL

Sororin Mediates Sister Chromatid Cohesion by Antagonizing Wapl

(2010) Tomoko Nishiyama et al.   CELL

ATP Hydrolysis Is Required for Relocating Cohesin from Sites Occupied by Its Scc2/4 Loading Complex

(2010) Bin Hu et al.   CURRENT BIOLOGY

Rec8 Phosphorylation by Casein Kinase 1 and Cdc7-Dbf4 Kinase Regulates Cohesin Cleavage by Separase during Meiosis

(2010) Vittorio L. Katis et al.   DEVELOPMENTAL CELL

Kinetochore–microtubule interactions: steps towards bi-orientation

(2010) Tomoyuki U Tanaka   EMBO JOURNAL

Phosphorylation of mammalian Sgo2 by Aurora B recruits PP2A and MCAK to centromeres

(2010) Y. Tanno et al.   GENES & DEVELOPMENT

Sgo1 establishes the centromeric cohesion protection mechanism in G2 before subsequent Bub1-dependent recruitment in mitosis

(2010) D. Perera et al.   JOURNAL OF CELL SCIENCE

Aurora B Phosphorylates Spatially Distinct Targets to Differentially Regulate the Kinetochore-Microtubule Interface

(2010) Julie P.I. Welburn et al.   MOLECULAR CELL

Phosphorylation of the CPC by Cdk1 promotes chromosome bi-orientation

(2010) Tatsuya Tsukahara et al.   NATURE

Shugoshin–PP2A counteracts casein-kinase-1-dependent cleavage of Rec8 by separase

(2010) Tadashi Ishiguro et al.   NATURE CELL BIOLOGY

Sororin cooperates with the acetyltransferase Eco2 to ensure DNA replication-dependent sister chromatid cohesion

(2010) A. L. Lafont et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two Histone Marks Establish the Inner Centromere and Chromosome Bi-Orientation

(2010) Yuya Yamagishi et al.   SCIENCE

Survivin Reads Phosphorylated Histone H3 Threonine 3 to Activate the Mitotic Kinase Aurora B

(2010) Alexander E. Kelly et al.   SCIENCE

Histone H3 Thr-3 Phosphorylation by Haspin Positions Aurora B at Centromeres in Mitosis

(2010) Fangwei Wang et al.   SCIENCE

Cohesin: Its Roles and Mechanisms

(2009) Kim Nasmyth et al.   Annual Review of Genetics

Budding Yeast Wpl1(Rad61)-Pds5 Complex Counteracts Sister Chromatid Cohesion-Establishing Reaction

(2009) Takashi Sutani et al.   CURRENT BIOLOGY

Releasing cohesin from chromosome arms in early mitosis: opposing actions of Wapl-Pds5 and Sgo1

(2009) K. Shintomi et al.   GENES & DEVELOPMENT

Shugoshin prevents cohesin cleavage by PP2ACdc55-dependent inhibition of separase

(2009) D. Clift et al.   GENES & DEVELOPMENT

Histone H3 Exerts a Key Function in Mitotic Checkpoint Control

(2009) J. Luo et al.   MOLECULAR AND CELLULAR BIOLOGY

Building Sister Chromatid Cohesion: Smc3 Acetylation Counteracts an Antiestablishment Activity

(2009) Benjamin D. Rowland et al.   MOLECULAR CELL

Structure and Function of the PP2A-Shugoshin Interaction

(2009) Zheng Xu et al.   MOLECULAR CELL

The chromosomal association of condensin II is regulated by a noncatalytic function of PP2A

(2009) Ai Takemoto et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Heterochromatin Protein 1 (HP1) Proteins Do Not Drive Pericentromeric Cohesin Enrichment in Human Cells

(2009) Ángel Serrano et al.   PLoS One

Sensing Chromosome Bi-Orientation by Spatial Separation of Aurora B Kinase from Kinetochore Substrates

(2009) D. Liu et al.   SCIENCE

Phosphorylation of H2A by Bub1 Prevents Chromosomal Instability Through Localizing Shugoshin

(2009) S. A. Kawashima et al.   SCIENCE

Conserved features of cohesin binding along fission yeast chromosomes

(2009) Christine K Schmidt et al.   GENOME BIOLOGY

Shugoshin regulates cohesion by driving relocalization of PP2A in Xenopus extracts

(2008) Teresa Rivera et al.   CHROMOSOMA

Shugoshin-2 is essential for the completion of meiosis but not for mitotic cell division in mice

(2008) E. Llano et al.   GENES & DEVELOPMENT

Identification of cis-acting sites for condensin loading onto budding yeast chromosomes

(2008) C. D'Ambrosio et al.   GENES & DEVELOPMENT

Multiple Anaphase-promoting Complex/Cyclosome Degrons Mediate the Degradation of Human Sgo1

(2008) Zemfira Karamysheva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acetylation of Smc3 by Eco1 Is Required for S Phase Sister Chromatid Cohesion in Both Human and Yeast

(2008) Jinglan Zhang et al.   MOLECULAR CELL

Heterochromatin links to centromeric protection by recruiting shugoshin

(2008) Yuya Yamagishi et al.   NATURE

Epigenetic regulation of centromeric chromatin: old dogs, new tricks?

(2008) Robin C. Allshire et al.   NATURE REVIEWS GENETICS

A Molecular Determinant for the Establishment of Sister Chromatid Cohesion

(2008) E. U nal et al.   SCIENCE

Eco1-Dependent Cohesin Acetylation During Establishment of Sister Chromatid Cohesion

(2008) T. R. Ben-Shahar et al.   SCIENCE

Shugoshin Promotes Sister Kinetochore Biorientation in Saccharomyces cerevisiae

(2007) Brendan M. Kiburz et al.   MOLECULAR BIOLOGY OF THE CELL