Insights into variation in meiosis from 31,228 human sperm genomes

Factors influencing meiotic recombination revealed by whole-genome sequencing of single sperm

(2019) Anjali Gupta Hinch et al.   SCIENCE

Characterizing mutagenic effects of recombination through a sequence-level genetic map

(2019) Bjarni V. Halldorsson et al.   SCIENCE

Per-Nucleus Crossover Covariation and Implications for Evolution

(2019) Shunxin Wang et al.   CELL

Correlations between Synaptic Initiation and Meiotic Recombination: A Study of Humans and Mice

(2016) Jennifer R. Gruhn et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Haplotyping germline and cancer genomes with high-throughput linked-read sequencing

(2016) Grace X Y Zheng et al.   NATURE BIOTECHNOLOGY

Reference-based phasing using the Haplotype Reference Consortium panel

(2016) Po-Ru Loh et al.   NATURE GENETICS

Fast and accurate long-range phasing in a UK Biobank cohort

(2016) Po-Ru Loh et al.   NATURE GENETICS

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Meiotic crossover patterns: Obligatory crossover, interference and homeostasis in a single process

(2015) Shunxin Wang et al.   CELL CYCLE

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Genome-wide maps of recombination and chromosome segregation in human oocytes and embryos show selection for maternal recombination rates

(2015) Christian S Ottolini et al.   NATURE GENETICS

Large multiallelic copy number variations in humans

(2015) Robert E Handsaker et al.   NATURE GENETICS

A Rapid Molecular Approach for Chromosomal Phasing

(2015) John F. Regan et al.   PLoS One

Topoisomerase II mediates meiotic crossover interference

(2014) Liangran Zhang et al.   NATURE

Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

(2014) Giulio Genovese et al.   NEW ENGLAND JOURNAL OF MEDICINE

Crossover Patterning by the Beam-Film Model: Analysis and Implications

(2014) Liangran Zhang et al.   PLoS Genetics

Genome Analyses of Single Human Oocytes

(2013) Yu Hou et al.   CELL

Sequencing of isolated sperm cells for direct haplotyping of a human genome

(2013) E. F. Kirkness et al.   GENOME RESEARCH

New insights on the origin and relevance of aneuploidy in human spermatozoa

(2013) C. Templado et al.   MOLECULAR HUMAN REPRODUCTION

Whole-genome haplotype reconstruction using proximity-ligation and shotgun sequencing

(2013) Siddarth Selvaraj et al.   NATURE BIOTECHNOLOGY

Common and low-frequency variants associated with genome-wide recombination rate

(2013) Augustine Kong et al.   NATURE GENETICS

Cytological Studies of Human Meiosis: Sex-Specific Differences in Recombination Originate at, or Prior to, Establishment of Double-Strand Breaks

(2013) Jennifer R. Gruhn et al.   PLoS One

Genome-wide Single-Cell Analysis of Recombination Activity and De Novo Mutation Rates in Human Sperm

(2012) Jianbin Wang et al.   CELL

Human aneuploidy: mechanisms and new insights into an age-old problem

(2012) So I. Nagaoka et al.   NATURE REVIEWS GENETICS

Probing Meiotic Recombination and Aneuploidy of Single Sperm Cells by Whole-Genome Sequencing

(2012) S. Lu et al.   SCIENCE

Discovery and genotyping of genome structural polymorphism by sequencing on a population scale

(2011) Robert E Handsaker et al.   NATURE GENETICS

Variation in Human Recombination Rates and Its Genetic Determinants

(2011) Adi Fledel-Alon et al.   PLoS One

Distinct Properties of the XY Pseudoautosomal Region Crucial for Male Meiosis

(2011) L. Kauppi et al.   SCIENCE

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Fine-scale recombination rate differences between sexes, populations and individuals

(2010) Augustine Kong et al.   NATURE

PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans

(2010) Ingrid L Berg et al.   NATURE GENETICS

Patterns of Recombination Activity on Mouse Chromosome 11 Revealed by High Resolution Mapping

(2010) Timothy Billings et al.   PLoS One

Investigation of factors associated with paternal nondisjunction of chromosome 21

(2009) Tiffany Renee Oliver et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Paternal DNA packaging in spermatozoa: more than the sum of its parts? DNA, histones, protamines and epigenetics

(2009) David Miller et al.   REPRODUCTION

Genetic Analysis of Variation in Human Meiotic Recombination

(2009) Reshmi Chowdhury et al.   PLoS Genetics

HapCUT: an efficient and accurate algorithm for the haplotype assembly problem

(2008) V. Bansal et al.   BIOINFORMATICS

The relationship between meiotic recombination in human spermatocytes and aneuploidy in sperm

(2008) F. Sun et al.   HUMAN REPRODUCTION

A common sequence motif associated with recombination hot spots and genome instability in humans

(2008) Simon Myers et al.   NATURE GENETICS

High-Resolution Mapping of Crossovers Reveals Extensive Variation in Fine-Scale Recombination Patterns Among Humans

(2008) G. Coop et al.   SCIENCE