Context-specific regulation and function of mRNA alternative polyadenylation

RBBP6 activates the pre-mRNA 3′ end processing machinery in humans

(2022) Vytaute Boreikaite et al.   GENES & DEVELOPMENT

Heat shock induces premature transcript termination and reconfigures the human transcriptome

(2022) Simona Cugusi et al.   MOLECULAR CELL

Alternative polyadenylation by sequential activation of distal and proximal PolyA sites

(2022) Peng Tang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CRISPR-iPAS: a novel dCAS13-based method for alternative polyadenylation interference

(2022) Shuye Tian et al.   NUCLEIC ACIDS RESEARCH

CFIm-mediated alternative polyadenylation remodels cellular signaling and miRNA biogenesis

(2022) Souvik Ghosh et al.   NUCLEIC ACIDS RESEARCH

Enhancers regulate 3′ end processing activity to control expression of alternative 3′UTR isoforms

(2022) Buki Kwon et al.   Nature Communications

Epidermal progenitors suppress GRHL3-mediated differentiation through intronic polyadenylation promoted by CPSF-HNRNPA3 collaboration

(2021) Xin Chen et al.   Nature Communications

Downregulation of NUDT21 contributes to cervical cancer progression through alternative polyadenylation

(2021) Yifei Xing et al.   ONCOGENE

Crosstalk Between mRNA 3'-End Processing and Epigenetics

(2021) Lindsey V. Soles et al.   Frontiers in Genetics

Protein phosphatases in the RNAPII transcription cycle: erasers, sculptors, gatekeepers, and potential drug targets

(2021) Giacomo Cossa et al.   GENES & DEVELOPMENT

An atlas of alternative polyadenylation quantitative trait loci contributing to complex trait and disease heritability

(2021) Lei Li et al.   NATURE GENETICS

On the Cutting Edge: Regulation and Therapeutic Potential of the mRNA 3′ End Nuclease

(2021) Huiyun Liu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Parallel genetics of regulatory sequences using scalable genome editing in vivo

(2021) Jonathan J. Froehlich et al.   Cell Reports

Endogenous p53 expression in human and mouse is not regulated by its 3′UTR

(2021) Sibylle Mitschka et al.   eLife

CRISPRpas: programmable regulation of alternative polyadenylation by dCas9

(2021) Jihae Shin et al.   NUCLEIC ACIDS RESEARCH

Shortening of 3p UTRs in most cell types composing tumor tissues implicates alternative polyadenylation in protein metabolism

(2021) Dominik Burri et al.   RNA

The landscape of alternative polyadenylation in single cells of the developing mouse embryo

(2021) Vikram Agarwal et al.   Nature Communications

Alternative 3′ UTRs play a widespread role in translation-independent mRNA association with the endoplasmic reticulum

(2021) Larry C. Cheng et al.   Cell Reports

A working model for condensate RNA-binding proteins as matchmakers for protein complex assembly

(2021) Xiuzhen Chen et al.   RNA

Alternative polyadenylation is a determinant of oncogenic Ras function

(2021) Aishwarya Subramanian et al.   Science Advances

A Cancer-Specific Ubiquitin Ligase Drives mRNA Alternative Polyadenylation by Ubiquitinating the mRNA 3′ End Processing Complex

(2020) Seung Wook Yang et al.   MOLECULAR CELL

Casein Kinase 1δ Stabilizes Mature Axons by Inhibiting Transcription Termination of Ankyrin

(2020) Matthew L. LaBella et al.   DEVELOPMENTAL CELL

tRIP‐seq reveals repression of premature polyadenylation by co‐transcriptional FUS‐U1 snRNP assembly

(2020) Akio Masuda et al.   EMBO REPORTS

DNA Methylation Regulates Alternative Polyadenylation via CTCF and the Cohesin Complex

(2020) Vishal Nanavaty et al.   MOLECULAR CELL

CDK13 cooperates with CDK12 to control global RNA polymerase II processivity

(2020) Zheng Fan et al.   Science Advances

CDK12 globally stimulates RNA polymerase II transcription elongation and carboxyl-terminal domain phosphorylation

(2020) Michael Tellier et al.   NUCLEIC ACIDS RESEARCH

RPS28B mRNA acts as a scaffold promoting cis-translational interaction of proteins driving P-body assembly

(2020) Nikita Fernandes et al.   NUCLEIC ACIDS RESEARCH

Elimination of Calm1 long 3' UTR mRNA isoform by CRISPR-Cas9 gene editing impairs dorsal root ganglion development and hippocampal neuron activation in mice

(2020) Bongmin Bae et al.   RNA

Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation

(2020) Larry C. Cheng et al.   Nature Communications

Alternative polyadenylation mediates genetic regulation of gene expression

(2020) Briana E Mittleman et al.   eLife

NEAT1 polyA-modulating antisense oligonucleotides reveal opposing functions for both long non-coding RNA isoforms in neuroblastoma

(2020) Alina Naveed et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

ELAV and FNE Determine Neuronal Transcript Signatures through EXon-Activated Rescue

(2020) Judit Carrasco et al.   MOLECULAR CELL

Integrator Recruits Protein Phosphatase 2A to Prevent Pause Release and Facilitate Transcription Termination

(2020) Kai-Lieh Huang et al.   MOLECULAR CELL

TREND-DB—a transcriptome-wide atlas of the dynamic landscape of alternative polyadenylation

(2020) Federico Marini et al.   NUCLEIC ACIDS RESEARCH

Termination of Transcription by RNA Polymerase II: BOOM!

(2020) Joshua D. Eaton et al.   TRENDS IN GENETICS

Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases

(2020) Seung Wook Yang et al.   Nature Communications

RBP2GO: a comprehensive pan-species database on RNA-binding proteins, their interactions and functions

(2020) Maiwen Caudron-Herger et al.   NUCLEIC ACIDS RESEARCH

Regulation of Intronic Polyadenylation by PCF11 Impacts mRNA Expression of Long Genes

(2019) Ruijia Wang et al.   Cell Reports

Tissue-specificity in cancer: The rule, not the exception

(2019) Kevin M. Haigis et al.   SCIENCE

Nudt21 regulates the alternative polyadenylation of Pak1 and is predictive in the prognosis of glioblastoma patients

(2019) Yuan Chu et al.   ONCOGENE

Selective Roles of Vertebrate PCF11 in Premature and Full-Length Transcript Termination

(2019) Kinga Kamieniarz-Gdula et al.   MOLECULAR CELL

The mRNA Export Receptor NXF1 Coordinates Transcriptional Dynamics, Alternative Polyadenylation, and mRNA Export

(2019) Suli Chen et al.   MOLECULAR CELL

Alternative polyadenylation dependent function of splicing factor SRSF3 contributes to cellular senescence

(2019) Ting Shen et al.   Aging-US

A PolH transcript with a short 3'UTR enhances PolH expression and mediates cisplatin resistance

(2019) Jin Zhang et al.   CANCER RESEARCH

SCAF4 and SCAF8, mRNA Anti-Terminator Proteins

(2019) Lea H. Gregersen et al.   CELL

Gain of Additional BIRC3 Protein Functions through 3ʹ-UTR-Mediated Protein Complex Formation

(2019) Shih-Han Lee et al.   MOLECULAR CELL

R-DeeP: Proteome-wide and Quantitative Identification of RNA-Dependent Proteins by Density Gradient Ultracentrifugation

(2019) Maiwen Caudron-Herger et al.   MOLECULAR CELL

Local protein synthesis is a ubiquitous feature of neuronal pre- and postsynaptic compartments

(2019) Anne-Sophie Hafner et al.   SCIENCE

Single-cell genomics identifies cell type–specific molecular changes in autism

(2019) Dmitry Velmeshev et al.   SCIENCE

A Deep Neural Network for Predicting and Engineering Alternative Polyadenylation

(2019) Nicholas Bogard et al.   CELL

Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription

(2019) Rui Xiao et al.   CELL

Alternative cleavage and polyadenylation in health and disease

(2019) Andreas J. Gruber et al.   NATURE REVIEWS GENETICS

CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation

(2019) Malgorzata Krajewska et al.   Nature Communications

Live cell imaging reveals 3′-UTR dependent mRNA sorting to synapses

(2019) Karl E. Bauer et al.   Nature Communications

FLAM-seq: full-length mRNA sequencing reveals principles of poly(A) tail length control

(2019) Ivano Legnini et al.   NATURE METHODS

Cell-type-specific analysis of alternative polyadenylation using single-cell transcriptomics data

(2019) Eldad David Shulman et al.   NUCLEIC ACIDS RESEARCH

RNA Binding Protein CELF2 Regulates Signal-Induced Alternative Polyadenylation by Competing with Enhancers of the Polyadenylation Machinery

(2019) Rakesh Chatrikhi et al.   Cell Reports

The Length of the Expressed 3′ UTR Is an Intermediate Molecular Phenotype Linking Genetic Variants to Complex Diseases

(2019) Elisa Mariella et al.   Frontiers in Genetics

Full-length transcriptome reconstruction reveals a large diversity of RNA and protein isoforms in rat hippocampus

(2019) Xi Wang et al.   Nature Communications

Control of RNA Pol II Speed by PNUTS-PP1 and Spt5 Dephosphorylation Facilitates Termination by a “Sitting Duck Torpedo” Mechanism

(2019) Michael A. Cortazar et al.   MOLECULAR CELL

CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma

(2019) Nathan T. Ross et al.   Nature Chemical Biology

The human ZC3H3 and RBM26/27 proteins are critical for PAXT-mediated nuclear RNA decay

(2019) Toomas Silla et al.   NUCLEIC ACIDS RESEARCH

Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling

(2018) Justin Brumbaugh et al.   CELL

The TORC1-Regulated CPA Complex Rewires an RNA Processing Network to Drive Autophagy and Metabolic Reprogramming

(2018) Hong-Wen Tang et al.   Cell Metabolism

Molecular Mechanisms for CFIm-Mediated Regulation of mRNA Alternative Polyadenylation

(2018) Yong Zhu et al.   MOLECULAR CELL

Alternative 3′ UTRs Modify the Localization, Regulatory Potential, Stability, and Plasticity of mRNAs in Neuronal Compartments

(2018) Georgi Tushev et al.   NEURON

NUDT21 negatively regulates PSMB2 and CXXC5 by alternative polyadenylation and contributes to hepatocellular carcinoma suppression

(2018) Sheng Tan et al.   ONCOGENE

Locally translated mTOR controls axonal local translation in nerve injury

(2018) Marco Terenzio et al.   SCIENCE

Widespread intronic polyadenylation diversifies immune cell transcriptomes

(2018) Irtisha Singh et al.   Nature Communications

Cellular stress alters 3′UTR landscape through alternative polyadenylation and isoform-specific degradation

(2018) Dinghai Zheng et al.   Nature Communications

Post-transcriptional Regulation by 3′ UTRs Can Be Masked by Regulatory Elements in 5′ UTRs

(2018) Kathrin Theil et al.   Cell Reports

Regulation of circadian clock transcriptional output by CLOCK:BMAL1

(2018) Alexandra J. Trott et al.   PLoS Genetics

A compendium of conserved cleavage and polyadenylation events in mammalian genes

(2018) Ruijia Wang et al.   GENOME RESEARCH

Therapeutic Genome Editing for Myotonic Dystrophy Type 1 Using CRISPR/Cas9

(2018) Yanlin Wang et al.   MOLECULAR THERAPY

Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia

(2018) Shih-Han Lee et al.   NATURE

Terminal exon characterization with TECtool reveals an abundance of cell-specific isoforms

(2018) Andreas J. Gruber et al.   NATURE METHODS

What Are 3′ UTRs Doing?

(2018) Christine Mayr   Cold Spring Harbor Perspectives in Biology

A Membraneless Organelle Associated with the Endoplasmic Reticulum Enables 3′UTR-Mediated Protein-Protein Interactions

(2018) Weirui Ma et al.   CELL

Spatiotemporal m(i)RNA Architecture and 3′ UTR Regulation in the C. elegans Germline

(2018) Asija Diag et al.   DEVELOPMENTAL CELL

Widespread Backtracking by RNA Pol II Is a Major Effector of Gene Activation, 5′ Pause Release, Termination, and Transcription Elongation Rate

(2018) Ryan M. Sheridan et al.   MOLECULAR CELL

Improving mRNA-Based Therapeutic Gene Delivery by Expression-Augmenting 3′ UTRs Identified by Cellular Library Screening

(2018) Alexandra G. Orlandini von Niessen et al.   MOLECULAR THERAPY

CDK12 regulates DNA repair genes by suppressing intronic polyadenylation

(2018) Sara J. Dubbury et al.   NATURE

Alternative 3′ UTRs direct localization of functionally diverse protein isoforms in neuronal compartments

(2018) Camilla Ciolli Mattioli et al.   NUCLEIC ACIDS RESEARCH

Transcriptome 3′end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma

(2018) Anton Ogorodnikov et al.   Nature Communications

Membrane-Associated RNA-Binding Proteins Orchestrate Organelle-Coupled Translation

(2018) Julien Béthune et al.   TRENDS IN CELL BIOLOGY

Two distinct transcription termination modes dictated by promoters

(2017) Takashi S. Miki et al.   GENES & DEVELOPMENT

Comprehensive Characterization of Alternative Polyadenylation in Human Cancer

(2017) Yu Xiang et al.   JNCI-Journal of the National Cancer Institute

Genetic effects on gene expression across human tissues

(2017) François Aguet et al.   NATURE

CRISPR–Cas9-mediated functional dissection of 3′-UTRs

(2017) Wenxue Zhao et al.   NUCLEIC ACIDS RESEARCH

In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering

(2017) Qianxin Wu et al.   Nature Communications

Comprehensive Characterization of Alternative Polyadenylation in Human Cancer

(2017) Yu Xiang et al.   JNCI-Journal of the National Cancer Institute

SR proteins are NXF1 adaptors that link alternative RNA processing to mRNA export

(2016) Michaela Müller-McNicoll et al.   GENES & DEVELOPMENT

A comprehensive analysis of 3′ end sequencing data sets reveals novel polyadenylation signals and the repressive role of heterogeneous ribonucleoprotein C on cleavage and polyadenylation

(2016) Andreas J. Gruber et al.   GENOME RESEARCH

Antisense targeting of 3′ end elements involved inDUX4mRNA processing is an efficient therapeutic strategy for facioscapulohumeral dystrophy: a new gene-silencing approach

(2016) Anne-Charlotte Marsollier et al.   HUMAN MOLECULAR GENETICS

Promoter-Terminator Gene Loops Affect Alternative 3′-End Processing in Yeast

(2016) Mónica Lamas-Maceiras et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distal Alternative Last Exons Localize mRNAs to Neural Projections

(2016) J. Matthew Taliaferro et al.   MOLECULAR CELL

SONAR Discovers RNA-Binding Proteins from Analysis of Large-Scale Protein-Protein Interactomes

(2016) Kristopher W. Brannan et al.   MOLECULAR CELL

Morpholino-mediated Knockdown of DUX4 Toward Facioscapulohumeral Muscular Dystrophy Therapeutics

(2016) Jennifer CJ Chen et al.   MOLECULAR THERAPY

Alternative polyadenylation of mRNA precursors

(2016) Bin Tian et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The pol II CTD: new twists in the tail

(2016) Justyna Zaborowska et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The pol II CTD: new twists in the tail

(2016) Justyna Zaborowska et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

PAF Complex Plays Novel Subunit-Specific Roles in Alternative Cleavage and Polyadenylation

(2016) Yan Yang et al.   PLoS Genetics

Position-specific binding of FUS to nascent RNA regulates mRNA length

(2015) Akio Masuda et al.   GENES & DEVELOPMENT

Context-dependent modulation of Pol II CTD phosphatase SSUP-72 regulates alternative polyadenylation in neuronal development

(2015) Fei Chen et al.   GENES & DEVELOPMENT

Subcellular RNA profiling links splicing and nuclear DICER1 to alternative cleavage and polyadenylation

(2015) Jonathan Neve et al.   GENOME RESEARCH

Growth Cone Localization of the mRNA Encoding the Chromatin Regulator HMGN5 Modulates Neurite Outgrowth

(2015) Francesca Moretti et al.   MOLECULAR AND CELLULAR BIOLOGY

ELAV Links Paused Pol II to Alternative Polyadenylation in the Drosophila Nervous System

(2015) Katarzyna Oktaba et al.   MOLECULAR CELL

Alternative 3′ UTRs act as scaffolds to regulate membrane protein localization

(2015) Binyamin D. Berkovits et al.   NATURE

CDK9 inhibitors define elongation checkpoints at both ends of RNA polymerase II–transcribed genes

(2015) Clélia Laitem et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RNA polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II

(2015) M. Yu et al.   SCIENCE

CDK9 inhibitors define elongation checkpoints at both ends of RNA polymerase II–transcribed genes

(2015) Clélia Laitem et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Systematic Profiling of Poly(A)+ Transcripts Modulated by Core 3’ End Processing and Splicing Factors Reveals Regulatory Rules of Alternative Cleavage and Polyadenylation

(2015) Wencheng Li et al.   PLoS Genetics

Fip1 regulates mRNA alternative polyadenylation to promote stem cell self-renewal

(2014) B. Lackford et al.   EMBO JOURNAL

CPSF30 and Wdr33 directly bind to AAUAAA in mammalian mRNA 3′ processing

(2014) Serena L. Chan et al.   GENES & DEVELOPMENT

Reconstitution of CPSF active in polyadenylation: recognition of the polyadenylation signal by WDR33

(2014) Lars Schönemann et al.   GENES & DEVELOPMENT

Loss of MBNL Leads to Disruption of Developmentally Regulated Alternative Polyadenylation in RNA-Mediated Disease

(2014) Ranjan Batra et al.   MOLECULAR CELL

Promoter sequences direct cytoplasmic localization and translation of mRNAs during starvation in yeast

(2014) Brian M. Zid et al.   NATURE

CFIm25 links alternative polyadenylation to glioblastoma tumour suppression

(2014) Chioniso P. Masamha et al.   NATURE

A recently evolved class of alternative 3′-terminal exons involved in cell cycle regulation by topoisomerase inhibitors

(2014) Martin Dutertre et al.   Nature Communications

Global 3′ UTR shortening has a limited effect on protein abundance in proliferating T cells

(2014) Andreas R. Gruber et al.   Nature Communications

Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3′-UTR landscape across seven tumour types

(2014) Zheng Xia et al.   Nature Communications

The fate of the messenger is pre-determined: A new model for regulation of gene expression

(2013) Gal Haimovich et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression

(2013) S. Lianoglou et al.   GENES & DEVELOPMENT

3' UTR-isoform choice has limited influence on the stability and translational efficiency of most mRNAs in mouse fibroblasts

(2013) N. Spies et al.   GENOME RESEARCH

 CP Poly(C) Binding Proteins Act as Global Regulators of Alternative Polyadenylation

(2013) X. Ji et al.   MOLECULAR AND CELLULAR BIOLOGY

CPEB1 coordinates alternative 3′-UTR formation with translational regulation

(2013) Felice-Alessio Bava et al.   NATURE

Human TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor I

(2013) J. Katahira et al.   NUCLEIC ACIDS RESEARCH

Exploring mRNA 3′-UTR G-quadruplexes: evidence of roles in both alternative polyadenylation and mRNA shortening

(2013) Jean-Denis Beaudoin et al.   NUCLEIC ACIDS RESEARCH

Cold-induced RNA-binding proteins regulate circadian gene expression by controlling alternative polyadenylation

(2013) Yuting Liu et al.   Scientific Reports

The Conserved Intronic Cleavage and Polyadenylation Site of CstF-77 Gene Imparts Control of 3′ End Processing Activity through Feedback Autoregulation and by U1 snRNP

(2013) Wenting Luo et al.   PLoS Genetics

CREPT Accelerates Tumorigenesis by Regulating the Transcription of Cell-Cycle-Related Genes

(2012) Dongdong Lu et al.   CANCER CELL

The Poly(A)-Binding Protein Nuclear 1 Suppresses Alternative Cleavage and Polyadenylation Sites

(2012) Mathias Jenal et al.   CELL

U1 snRNP Determines mRNA Length and Regulates Isoform Expression

(2012) Michael G. Berg et al.   CELL

ELAV mediates 3' UTR extension in the Drosophila nervous system

(2012) V. Hilgers et al.   GENES & DEVELOPMENT

A quantitative atlas of polyadenylation in five mammals

(2012) Adnan Derti et al.   GENOME RESEARCH

A Universal RNA Polymerase II CTD Cycle Is Orchestrated by Complex Interplays between Kinase, Phosphatase, and Isomerase Enzymes along Genes

(2012) Alain R. Bataille et al.   MOLECULAR CELL

The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts

(2012) Alexander G. Baltz et al.   MOLECULAR CELL

Analysis of alternative cleavage and polyadenylation by 3′ region extraction and deep sequencing

(2012) Mainul Hoque et al.   NATURE METHODS

Cleavage factor Imis a key regulator of 3′ UTR length

(2012) Andreas R. Gruber et al.   RNA Biology

Gene Loops Enhance Transcriptional Directionality

(2012) S. M. Tan-Wong et al.   SCIENCE

Modulation of immune signalling by inhibitors of apoptosis

(2012) Shawn T. Beug et al.   TRENDS IN IMMUNOLOGY

Promoter Elements Regulate Cytoplasmic mRNA Decay

(2011) Almog Bregman et al.   CELL

Single-Molecule mRNA Decay Measurements Reveal Promoter- Regulated mRNA Stability in Yeast

(2011) Tatjana Trcek et al.   CELL

RNA polymerase II kinetics inpolopolyadenylation signal selection

(2011) Pedro A B Pinto et al.   EMBO JOURNAL

Transcriptional Activators Enhance Polyadenylation of mRNA Precursors

(2011) Takashi Nagaike et al.   MOLECULAR CELL

Human Senataxin Resolves RNA/DNA Hybrids Formed at Transcriptional Pause Sites to Promote Xrn2-Dependent Termination

(2011) Konstantina Skourti-Stathaki et al.   MOLECULAR CELL

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

(2011) Simon N Stacey et al.   NATURE GENETICS

Unravelling the means to an end: RNA polymerase II transcription termination

(2011) Jason N. Kuehner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Complex and dynamic landscape of RNA polyadenylation revealed by PAS-Seq

(2011) P. J. Shepard et al.   RNA

RNA Polymerase II Subunits Link Transcription and mRNA Decay to Translation

(2010) Liat Harel-Sharvit et al.   CELL

U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation

(2010) Daisuke Kaida et al.   NATURE

Crystal structure of the human symplekin–Ssu72–CTD phosphopeptide complex

(2010) Kehui Xiang et al.   NATURE

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

Molecular Architecture of the Human Pre-mRNA 3′ Processing Complex

(2009) Yongsheng Shi et al.   MOLECULAR CELL

The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3′ mRNA processing factors

(2009) Orit Rozenblatt-Rosen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Role of Long 3′ UTR BDNF mRNA in Spine Morphology and Synaptic Plasticity in Hippocampal Neurons

(2008) Juan Ji An et al.   CELL

HITS-CLIP yields genome-wide insights into brain alternative RNA processing

(2008) Donny D. Licatalosi et al.   NATURE

Intra-axonal translation and retrograde trafficking of CREB promotes neuronal survival

(2008) Llewellyn J. Cox et al.   NATURE CELL BIOLOGY

Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites

(2008) R. Sandberg et al.   SCIENCE