Human TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor I

Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor

(2012) Álvaro Peña et al.   EMBO JOURNAL

The RNA polymerase II CTD coordinates transcription and RNA processing

(2012) J.-P. Hsin et al.   GENES & DEVELOPMENT

TREX exposes the RNA-binding domain of Nxf1 to enable mRNA export

(2012) Nicolas Viphakone et al.   Nature Communications

Genome-wide Analysis of Pre-mRNA 3′ End Processing Reveals a Decisive Role of Human Cleavage Factor I in the Regulation of 3′ UTR Length

(2012) Georges Martin et al.   Cell Reports

mRNA export and the TREX complex

(2011) Jun Katahira   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers

(2011) María S Domínguez-Sánchez et al.   BMC CANCER

Linking gene regulation to mRNA production and export

(2011) Susana Rodríguez-Navarro et al.   CURRENT OPINION IN CELL BIOLOGY

The Prp19 complex is a novel transcription elongation factor required for TREX occupancy at transcribed genes

(2011) S. Chanarat et al.   GENES & DEVELOPMENT

Ending the message: poly(A) signals then and now

(2011) N. J. Proudfoot   GENES & DEVELOPMENT

Mechanisms and Consequences of Alternative Polyadenylation

(2011) Dafne Campigli Di Giammartino et al.   MOLECULAR CELL

Keeping mRNPs in check during assembly and nuclear export

(2011) Evelina Tutucci et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The export factor Yra1 modulates mRNA 3′ end processing

(2011) Sara A Johnson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification of mRNAs that are spliced but not exported to the cytoplasm in the absence of THOC5 in mouse embryo fibroblasts

(2011) A. Guria et al.   RNA

Crystal Structure of a Human Cleavage Factor CFIm25/CFIm68/RNA Complex Provides an Insight into Poly(A) Site Recognition and RNA Looping

(2011) Qin Yang et al.   STRUCTURE

A User's Guide to the Encyclopedia of DNA Elements (ENCODE)

(2011)   PLOS BIOLOGY

Genome Instability and Transcription Elongation Impairment in Human Cells Depleted of THO/TREX

(2011) María S. Domínguez-Sánchez et al.   PLoS Genetics

THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo

(2010) Annalisa Mancini et al.   BMC BIOLOGY

Multifunctional factor ENY2 is associated with the THO complex and promotes its recruitment onto nascent mRNA

(2010) D. V. Kopytova et al.   GENES & DEVELOPMENT

Crosstalk between mRNA 3′ End Processing and Transcription Initiation

(2010) Christophe K. Mapendano et al.   MOLECULAR CELL

Molecular mechanisms of eukaryotic pre-mRNA 3′ end processing regulation

(2010) Stefania Millevoi et al.   NUCLEIC ACIDS RESEARCH

Pre-mRNA Processing Reaches Back toTranscription and Ahead to Translation

(2009) Melissa J. Moore et al.   CELL

Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA

(2009) Jun Katahira et al.   EMBO JOURNAL

Transcriptional Termination Enhances Protein Expression in Human Cells

(2009) Steven West et al.   MOLECULAR CELL

“Cotranscriptionality”: The Transcription Elongation Complex as a Nexus for Nuclear Transactions

(2009) Roberto Perales et al.   MOLECULAR CELL

Consistency Analysis of Redundant Probe Sets on Affymetrix Three-Prime Expression Arrays and Applications to Differential mRNA Processing

(2009) Xiangqin Cui et al.   PLoS One

Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development

(2009) Z. Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

THO/Sub2p Functions to Coordinate 3′-End Processing with Gene-Nuclear Pore Association

(2008) Mathieu Rougemaille et al.   CELL

Quality control of mRNP in the nucleus

(2008) Manfred Schmid et al.   CHROMOSOMA

Nuclear mRNA Surveillance in THO/sub2 Mutants Is Triggered by Inefficient Polyadenylation

(2008) Cyril Saguez et al.   MOLECULAR CELL

Cotranscriptional Recruitment of the mRNA Export Factor Yra1 by Direct Interaction with the 3′ End Processing Factor Pcf11

(2008) Sara Ann Johnson et al.   MOLECULAR CELL

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites

(2008) R. Sandberg et al.   SCIENCE

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY

Definition of global and transcript-specific mRNA export pathways in metazoans

(2007) N. G. Farny et al.   GENES & DEVELOPMENT