Nudt21 regulates the alternative polyadenylation of Pak1 and is predictive in the prognosis of glioblastoma patients

Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling

(2018) Justin Brumbaugh et al.   CELL

Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling

(2018) Justin Brumbaugh et al.   CELL

Molecular Mechanisms for CFIm-Mediated Regulation of mRNA Alternative Polyadenylation

(2018) Yong Zhu et al.   MOLECULAR CELL

3′ UTR shortening represses tumor-suppressor genes in trans by disrupting ceRNA crosstalk

(2018) Hyun Jung Park et al.   NATURE GENETICS

Poly(A)-ClickSeq: click-chemistry for next-generation 3΄-end sequencing without RNA enrichment or fragmentation

(2017) Andrew Routh et al.   NUCLEIC ACIDS RESEARCH

An activating mutation of GNB1 is associated with resistance to tyrosine kinase inhibitors in ETV6-ABL1-positive leukemia

(2017) O Zimmermannova et al.   ONCOGENE

Cleavage factor Im (CFIm) as a regulator of alternative polyadenylation

(2016) J. G. Hardy et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non‐coding RNA and synonymous mutations

(2016) Sven Diederichs et al.   EMBO Molecular Medicine

Alternative polyadenylation of mRNA precursors

(2016) Bin Tian et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin

(2016) Gregory A. Sowd et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CFIm25 regulates glutaminase alternative terminal exon definition to modulate miR-23 function

(2016) Chioniso P. Masamha et al.   RNA

PAK1 confers chemoresistance and poor outcome in non-small cell lung cancer via β-catenin-mediated stemness

(2016) Ming-Jenn Chen et al.   Scientific Reports

Genome-Wide Polyadenylation Maps Reveal Dynamic mRNA 3′-End Formation in the Failing Human HeartNovelty and Significance

(2015) Esther E. Creemers et al.   CIRCULATION RESEARCH

ClickSeq: Fragmentation-Free Next-Generation Sequencing via Click Ligation of Adaptors to Stochastically Terminated 3′-Azido cDNAs

(2015) Andrew Routh et al.   JOURNAL OF MOLECULAR BIOLOGY

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

p120-catenin participates in the progress of gastric cancer through regulating the Rac1 and Pak1 signaling pathway

(2015) TONG-FEI LI et al.   ONCOLOGY REPORTS

Driving glioblastoma growth by alternative polyadenylation

(2014) Ting Han et al.   CELL RESEARCH

Molecular Pathways: Targeting NRAS in Melanoma and Acute Myelogenous Leukemia

(2014) D. B. Johnson et al.   CLINICAL CANCER RESEARCH

CFIm25 links alternative polyadenylation to glioblastoma tumour suppression

(2014) Chioniso P. Masamha et al.   NATURE

Global 3′ UTR shortening has a limited effect on protein abundance in proliferating T cells

(2014) Andreas R. Gruber et al.   Nature Communications

Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3′-UTR landscape across seven tumour types

(2014) Zheng Xia et al.   Nature Communications

Growth arrest and forced differentiation of human primary glioblastoma multiforme by a novel small molecule

(2014) Tae-Wook Kang et al.   Scientific Reports

The Somatic Genomic Landscape of Glioblastoma

(2013) Cameron W. Brennan et al.   CELL

Alternative Polyadenylation in Glioblastoma Multiforme and Changes in Predicted RNA Binding Protein Profiles

(2013) Jiaofang Shao et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

A restricted cell population propagates glioblastoma growth after chemotherapy

(2012) Jian Chen et al.   NATURE

Estrogen-induced upregulation and 3′-UTR shortening of CDC6

(2012) Begum H. Akman et al.   NUCLEIC ACIDS RESEARCH

Cleavage factor Imis a key regulator of 3′ UTR length

(2012) Andreas R. Gruber et al.   RNA Biology

E2F mediates enhanced alternative polyadenylation in proliferation

(2012) Ran Elkon et al.   GENOME BIOLOGY

Differential genome-wide profiling of tandem 3' UTRs among human breast cancer and normal cells by high-throughput sequencing

(2011) Y. Fu et al.   GENOME RESEARCH

Crystal Structure of a Human Cleavage Factor CFIm25/CFIm68/RNA Complex Provides an Insight into Poly(A) Site Recognition and RNA Looping

(2011) Qin Yang et al.   STRUCTURE

Comprehensive Polyadenylation Site Maps in Yeast and Human Reveal Pervasive Alternative Polyadenylation

(2010) Fatih Ozsolak et al.   CELL

Glioblastoma cancer stem cells: heterogeneity, microenvironment and related therapeutic strategies

(2010) Tetyana Denysenko et al.   CELL BIOCHEMISTRY AND FUNCTION

Evidence that cleavage factor Im is a heterotetrameric protein complex controlling alternative polyadenylation

(2010) Sol Kim et al.   GENES TO CELLS

Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators

(2010) P. Nagarajan et al.   JOURNAL OF CELL SCIENCE

Glioblastoma stem-like cells give rise to tumour endothelium

(2010) Rong Wang et al.   NATURE

Structural basis of UGUA recognition by the Nudix protein CFIm25 and implications for a regulatory role in mRNA 3' processing

(2010) Q. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global Changes in Processing of mRNA 3' Untranslated Regions Characterize Clinically Distinct Cancer Subtypes

(2009) P. Singh et al.   CANCER RESEARCH

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

Gng12 is a novel negative regulator of LPS-induced inflammation in the microglial cell line BV-2

(2009) Kelley C. Larson et al.   INFLAMMATION RESEARCH

Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development

(2009) Z. Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Grb2 signaling in cell motility and cancer

(2008) Alessio Giubellino et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE