A Deep Neural Network for Predicting and Engineering Alternative Polyadenylation

Published 2019 View Full Article

Authors

Keywords

alternative polyadenylation, machine learning, deep learning, generative model, synthetic biology, massively parallel reporter assay, MPRA, single nucleotide variant, SNV, cis, -regulation, mRNA processing

Journal

CELL

Volume 178, Issue 1, Pages 91-106.e23

Publisher

Elsevier BV

Online

2019-06-06

DOI

10.1016/j.cell.2019.04.046

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