Virus-like Particles: Fundamentals and Biomedical Applications

Virus-Like Particles: Revolutionary Platforms for Developing Vaccines Against Emerging Infectious Diseases

(2022) Hasnat Tariq et al.   Frontiers in Microbiology

Virus-like Particles as Preventive and Therapeutic Cancer Vaccines

(2022) Anna Lucia Tornesello et al.   Vaccines

Review: A systematic review of virus-like particles of coronavirus: Assembly, generation, chimerism and their application in basic research and in the clinic

(2022) Wan Lu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Chitosan Nanoparticles-Insight into Properties, Functionalization and Applications in Drug Delivery and Theranostics

(2021) Jhanvi Jhaveri et al.   MOLECULES

Plant-Produced Antigen Displaying Virus-Like Particles Evokes Potent Antibody Responses against West Nile Virus in Mice

(2021) Junyun He et al.   Vaccines

Virus‐Based Nanoreactors with GALT Activity for Classic Galactosemia Therapy

(2021) Pedro Gama et al.   ChemMedChem

Hepatitis B Virus-Like Particle: Targeted Delivery of Plasmid Expressing Short Hairpin RNA for Silencing the Bcl-2 Gene in Cervical Cancer Cells

(2021) Made Angga Akwiditya et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chimeric Virus-Like Particles of Prawn Nodavirus Displaying Hepatitis B Virus Immunodominant Region: Biophysical Properties and Cytokine Response

(2021) Nathaniel Nyakaat Ninyio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Virus-like particles: preparation, immunogenicity and their roles as nanovaccines and drug nanocarriers

(2021) Saghi Nooraei et al.   JOURNAL OF NANOBIOTECHNOLOGY

P22 virus-like particles as an effective antigen delivery nanoplatform for cancer immunotherapy

(2021) Wenjing Li et al.   BIOMATERIALS

Delivering Two Tumour Antigens Survivin and Mucin-1 on Virus-Like Particles Enhances Anti-Tumour Immune Responses

(2021) Katrin Campbell et al.   Vaccines

Chimeric VLPs Based on HIV-1 Gag and a Fusion Rabies Glycoprotein Induce Specific Antibodies against Rabies and Foot-and-Mouth Disease Virus

(2021) Diego Fontana et al.   Vaccines

In Vitro Assembly of Virus-Like Particles and Their Applications

(2021) Dinh To Le et al.   Life-Basel

Characterization of Classical Vaccines by Charge Detection Mass Spectrometry

(2021) Lohra M. Miller et al.   ANALYTICAL CHEMISTRY

Single-Point Mutations in Qβ Virus-like Particles Change Binding to Cells

(2021) Marisa L. Martino et al.   BIOMACROMOLECULES

Stable Sf9 cell pools as a system for rapid HIV ‐1 virus‐like particle production

(2021) Eduard Puente‐Massaguer et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Safety and immunogenicity of a plant-derived rotavirus-like particle vaccine in adults, toddlers and infants

(2021) Natsuki Kurokawa et al.   VACCINE

The need for robust characterization of nanomaterials for nanomedicine applications

(2021) Morteza Mahmoudi   Nature Communications

Virus-like particles against infectious disease and cancer: guidance for the nano-architect

(2021) Rory A Hills et al.   CURRENT OPINION IN BIOTECHNOLOGY

Neural Network Modelling for Prediction of Zeta Potential

(2021) Roman Marsalek et al.   Mathematics

Genetic Engineering Strategies for Construction of Multivalent Chimeric VLPs Vaccines

(2020) Xinnuo Lei et al.   Expert Review of Vaccines

A bivalent, spherical virus-like particle vaccine enhances breadth of immune responses against pathogenic Ebola viruses in rhesus macaques

(2020) Karnail Singh et al.   JOURNAL OF VIROLOGY

Physical virology: From virus self‐assembly to particle mechanics

(2020) Pedro Buzón et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Virus Like Particles (VLP) as multivalent vaccine candidate against Chikungunya, Japanese Encephalitis, Yellow Fever and Zika Virus

(2020) Himanshu Garg et al.   Scientific Reports

Self-assembly into virus–like particles of the recombinant capsid protein of porcine circovirus type 3 and its application on antibodies detection

(2020) Yu Wang et al.   AMB Express

Supramolecular Encapsulation of Small-Ultrared Fluorescent Proteins in Virus-Like Nanoparticles for Noninvasive In Vivo Imaging Agents

(2020) Fabian C. Herbert et al.   BIOCONJUGATE CHEMISTRY

The 3Ds in virus-like particle based-vaccines: “Design, Delivery and Dynamics ”

(2020) Mona O. Mohsen et al.   IMMUNOLOGICAL REVIEWS

Immunogenicity of Protein Therapeutics: A Lymph Node Perspective

(2020) Kristy Fu et al.   Frontiers in Immunology

Recent Progress on the Versatility of Virus-Like Particles

(2020) Ciying Qian et al.   Vaccines

Viral nanoparticles for drug delivery, imaging, immunotherapy, and theranostic applications

(2020) Young Hun Chung et al.   ADVANCED DRUG DELIVERY REVIEWS

Interaction Between Virus-Like Particles (VLPs) and Pattern Recognition Receptors (PRRs) From Dendritic Cells (DCs): Toward Better Engineering of VLPs

(2020) Jesús Zepeda-Cervantes et al.   Frontiers in Immunology

Protein-Based Nanoparticles as Drug Delivery Systems

(2020) Seyoung Hong et al.   Pharmaceutics

Construction of SARS-CoV-2 Virus-Like Particles by Mammalian Expression System

(2020) Ruodan Xu et al.   Frontiers in Bioengineering and Biotechnology

Protein Nanocage Architectures for the Delivery of Therapeutic Proteins

(2020) Yang Wang et al.   CURRENT OPINION IN COLLOID & INTERFACE SCIENCE

Chimeric Virus-Like Particles and Capsomeres Induce Similar CD8+ T Cell Responses but Differ in Capacity to Induce CD4+ T Cell Responses and Antibody Responses

(2020) David J. Pattinson et al.   Frontiers in Immunology

Design Concepts of Virus-Like Particle-Based HIV-1 Vaccines

(2020) Chun-Wei Chen et al.   Frontiers in Immunology

Statistical Characterization of the Morphologies of Nanoparticles through Machine Learning Based Electron Microscopy Image Analysis

(2020) Byoungsang Lee et al.   ACS Nano

Effect of mutations in capsid shell protein on the assembly of BmCPV virus-like particles

(2020) Feifei Ren et al.   JOURNAL OF GENERAL VIROLOGY

Synthetic Virus-like Particles for Glutathione Biosynthesis

(2020) Yang Wang et al.   ACS Synthetic Biology

A Roadmap for the Molecular Farming of Viral Glycoprotein Vaccines: Engineering Glycosylation and Glycosylation-Directed Folding

(2020) Emmanuel Margolin et al.   Frontiers in Plant Science

Immunogenicity of Plant-Produced Human Papillomavirus (HPV) Virus-Like Particles (VLPs)

(2020) Paulina N. Naupu et al.   Vaccines

Functionalisation of Virus-Like Particles Enhances Antitumour Immune Responses

(2019) Katrin Kramer et al.   Journal of Immunology Research

Physalis Mottle Virus-like Nanoparticles for Targeted Cancer Imaging

(2019) He Hu et al.   ACS Applied Materials & Interfaces

Coronavirus envelope protein: current knowledge

(2019) Dewald Schoeman et al.   Virology Journal

Bioactivities of Flavonoids from Lopezia racemosa

(2019) Enrique Vergara Barragán et al.   Biomed Research International

Virus-like particle size and molecular weight/mass determination applying gas-phase electrophoresis (native nES GEMMA)

(2019) Victor U. Weiss et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Virus-Like Particles as an Instrument of Vaccine Production

(2019) B. V. Syomin et al.   MOLECULAR BIOLOGY

Efficient filtration strategies for the clarification of influenza virus-like particles derived from insect cells

(2019) Sofia B. Carvalho et al.   SEPARATION AND PURIFICATION TECHNOLOGY

Formation and Stability of Pea Proteins Nanoparticles Using Ethanol-Induced Desolvation

(2019) Chi Diem Doan et al.   Nanomaterials

Qß Virus-like particle-based vaccine induces robust immunity and protects against tauopathy

(2019) Nicole M. Maphis et al.   npj Vaccines

Virus‐like particles for vaccination against cancer

(2019) Mona O. Mohsen et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Electronic Circular Dichroism Spectroscopy of Proteins

(2019) David M. Rogers et al.   Chem

Production of HIV-1-based virus-like particles for vaccination: achievements and limits

(2019) Laura Cervera et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Structural puzzles in virology solved with an overarching icosahedral design principle

(2019) Reidun Twarock et al.   Nature Communications

Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure

(2019) Nicholas P. Stone et al.   Nature Communications

VLPs Derived from the CCMV Plant Virus Can Directly Transfect and Deliver Heterologous Genes for Translation into Mammalian Cells

(2019) María V. Villagrana-Escareño et al.   Biomed Research International

Plant-produced chimeric virus-like particles - a new generation vaccine against African horse sickness

(2019) Daria A. Rutkowska et al.   BMC Veterinary Research

Developments, applications, and prospects of cryo‐electron microscopy

(2019) Xu Benjin et al.   PROTEIN SCIENCE

Virus-Like Particle Engineering: From Rational Design to Versatile Applications

(2018) Xuanwei Ding et al.   Biotechnology Journal

Curating viscoelastic properties of icosahedral viruses, virus-based nanomaterials, and protein cages

(2018) Ravi Kant et al.   JOURNAL OF BIOLOGICAL PHYSICS

Electron cryomicroscopy as a powerful tool in biomedical research

(2018) Dennis Quentin et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Proteomic composition of Nipah virus -like particles

(2018) Natalia Mara Vera-Velasco et al.   Journal of Proteomics

Modularized peptides modified HBc virus-like particles for encapsulation and tumor-targeted delivery of doxorubicin

(2018) Wenjun Shan et al.   Nanomedicine-Nanotechnology Biology and Medicine

Characterization techniques for nanoparticles: comparison and complementarity upon studying nanoparticle properties

(2018) Stefanos Mourdikoudis et al.   Nanoscale

Nanoreactors: Strategies to encapsulate enzyme biocatalysts in virus-like particles

(2018) Joshua W. Wilkerson et al.   New Biotechnology

Morphological characterization of a plant-made virus-like particle vaccine bearing influenza virus hemagglutinins by electron microscopy

(2018) Brianne J. Lindsay et al.   VACCINE

Decoration of virus-like particles with an enzymatic activity of biomedical interest

(2018) Maribel Cayetano-Cruz et al.   VIRUS RESEARCH

Virus-Like Particle Engineering: From Rational Design to Versatile Applications

(2018) Xuanwei Ding et al.   Biotechnology Journal

Protein-Based Fiber Materials in Medicine: A Review

(2018) Kelsey DeFrates et al.   Nanomaterials

New Routes and Opportunities for Modular Construction of Particulate Vaccines: Stick, Click, and Glue

(2018) Karl D. Brune et al.   Frontiers in Immunology

Virus-like particle vaccines: immunology and formulation for clinical translation

(2018) Braeden Donaldson et al.   Expert Review of Vaccines

The Toxicity of Nanoparticles Depends on Multiple Molecular and Physicochemical Mechanisms

(2017) Yue-Wern Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Correlation between Dynamic Light Scattering and Size Exclusion High Performance Liquid Chromatography for Monitoring the Effect of pH on Stability of Biopharmaceuticals

(2017) Medhat A. Al-Ghobashy et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Monitoring the Disassembly of Virus-like Particles by 19F-NMR

(2017) Rogen L. C. Leung et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structures of Qβ virions, virus-like particles, and the Qβ–MurA complex reveal internal coat proteins and the mechanism of host lysis

(2017) Zhicheng Cui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biocatalytic virus capsid as nanovehicle for enzymatic activation of Tamoxifen in tumor cells

(2017) Alejandro Tapia-Moreno et al.   Biotechnology Journal

Advanced characterizations of nanoparticles for drug delivery: investigating their properties through the techniques used in their evaluations

(2017) Syed Mahmood et al.   Nanotechnology Reviews

Biomaterial-based nanoreactors, an alternative for enzyme delivery

(2017) Rina Koyani et al.   Nanotechnology Reviews

Virus like particles as a platform for cancer vaccine development

(2017) Hui Kian Ong et al.   PeerJ

Herpesviruses: epidemiology, pathogenesis, and interventions

(2017) Ke Lan et al.   VIROLOGICA SINICA

Difficulties and flaws in performing accurate determinations of zeta potentials of metal nanoparticles in complex solutions—Four case studies

(2017) Sara Skoglund et al.   PLoS One

Virus-like particles as drug delivery vectors

(2016) Michał Zdanowicz et al.   ACTA BIOCHIMICA POLONICA

DLS and zeta potential – What they are and what they are not?

(2016) Sourav Bhattacharjee   JOURNAL OF CONTROLLED RELEASE

Yeast as an expression system for producing virus-like particles: what factors do we need to consider?

(2016) H.J. Kim et al.   LETTERS IN APPLIED MICROBIOLOGY

Protein misfolding and aggregation: Mechanism, factors and detection

(2016) Sumit Kumar Chaturvedi et al.   PROCESS BIOCHEMISTRY

Engineering virus-like particles as vaccine platforms

(2016) Kathryn M Frietze et al.   Current Opinion in Virology

Nanoparticle Functionalization and Its Potentials for Molecular Imaging

(2016) Rukmani Thiruppathi et al.   Advanced Science

Stability of Secondary and Tertiary Structures of Virus-Like Particles Representing Noroviruses: Effects of pH, Ionic Strength, and Temperature and Implications for Adhesion to Surfaces

(2015) Idrissa Samandoulgou et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Different applications of virus-like particles in biology and medicine: Vaccination and delivery systems

(2015) Zeinab Shirbaghaee et al.   BIOPOLYMERS

Enveloped virus-like particles as vaccines against pathogenic arboviruses

(2015) Gorben P. Pijlman   Biotechnology Journal

NMR Techniques for Noble Metal Nanoparticles

(2015) Lauren E. Marbella et al.   CHEMISTRY OF MATERIALS

Chimeric Virus-Like Particles Made Using GAG and M1 Capsid Proteins Providing Dual Drug Delivery and Vaccination Platform

(2015) Vipin K. Deo et al.   MOLECULAR PHARMACEUTICS

Development of Rous sarcoma Virus-like Particles Displaying hCC49 scFv for Specific Targeted Drug Delivery to Human Colon Carcinoma Cells

(2015) Tatsuya Kato et al.   PHARMACEUTICAL RESEARCH

Accurate secondary structure prediction and fold recognition for circular dichroism spectroscopy

(2015) András Micsonai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Particle size and zeta potential investigation of synthetic peptide-protein conjugates / Sentetik peptid-protein konjugatlarının parçacık boyutu ve zeta potensiyel analizi

(2015) Serap Derman et al.   Turkish Journal of Biochemistry-Turk Biyokimya Dergisi

Zeta Potential and Aggregation of Virus-Like Particle of Human Norovirus and Feline Calicivirus Under Different Physicochemical Conditions

(2015) Idrissa Samandoulgou et al.   Food and Environmental Virology

Affinity selection of epitope-based vaccines using a bacteriophage virus-like particle platform

(2015) John P O’Rourke et al.   Current Opinion in Virology

Enveloped virus-like particles as vaccines against pathogenic arboviruses

(2015) Gorben P. Pijlman   Biotechnology Journal

Recombinant Hepatitis E virus like particles can function as RNA nanocarriers

(2015) Subrat Kumar Panda et al.   JOURNAL OF NANOBIOTECHNOLOGY

Design of a VLP-nanovehicle for CYP450 enzymatic activity delivery

(2015) Lorena Sánchez-Sánchez et al.   JOURNAL OF NANOBIOTECHNOLOGY

Biological Responses to Engineered Nanomaterials: Needs for the Next Decade

(2015) Catherine J. Murphy et al.   ACS Central Science

Self-assembly of peptides to nanostructures

(2014) Dindyal Mandal et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Anti-Leishmanial, Anti-Inflammatory and Antimicrobial Activities of Phenolic Derivatives fromTibouchina paratropica

(2014) María I. Tracanna et al.   PHYTOTHERAPY RESEARCH

New pharmacological strategies to fight enveloped viruses

(2014) Karin Wisskirchen et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Human antibody response to N-glycans present on plant-made influenza virus-like particle (VLP) vaccines

(2014) Brian J. Ward et al.   VACCINE

Mass spectrometry for the characterisation of nanoparticles

(2013) Antonio R. Montoro Bustos et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Bioengineering virus-like particles as vaccines

(2013) Linda H.L. Lua et al.   BIOTECHNOLOGY AND BIOENGINEERING

Functionalizing Nanoparticles with Biological Molecules: Developing Chemistries that Facilitate Nanotechnology

(2013) Kim E. Sapsford et al.   CHEMICAL REVIEWS

Reengineering viruses and virus-like particles through chemical functionalization strategies

(2013) Mark Thomas Smith et al.   CURRENT OPINION IN BIOTECHNOLOGY

NMR methods for structural studies of large monomeric and multimeric proteins

(2013) Dominique P Frueh et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Insect cells as a production platform of complex virus-like particles

(2013) Fabiana Fernandes et al.   Expert Review of Vaccines

Development of Virus-Like Particle Technology from Small Highly Symmetric to Large Complex Virus-Like Particle Structures

(2013) Peter Pushko et al.   INTERVIROLOGY

Use of baculovirus expression system for generation of virus-like particles: Successes and challenges

(2013) Fuxiao Liu et al.   PROTEIN EXPRESSION AND PURIFICATION

Virus-based nanocarriers for drug delivery

(2012) Yujie Ma et al.   ADVANCED DRUG DELIVERY REVIEWS

Protein analysis by dynamic light scattering: Methods and techniques for students

(2012) Bernard Lorber et al.   BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION

Engineered Mutations Change the Structure and Stability of a Virus-Like Particle

(2012) Jason D. Fiedler et al.   BIOMACROMOLECULES

Vaccination with coxsackievirus B3 virus-like particles elicits humoral immune response and protects mice against myocarditis

(2012) L. Zhang et al.   VACCINE

Virus-like particles: The new frontier of vaccines for animal viral infections

(2012) Elisa Crisci et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Virus-like particle (VLP)-based vaccines for pandemic influenza

(2012) Constantino López-Macías   Human Vaccines & Immunotherapeutics

Plant-derived virus-like particles as vaccines

(2012) Qiang Chen et al.   Human Vaccines & Immunotherapeutics

Cell-Specific Delivery of Diverse Cargos by Bacteriophage MS2 Virus-like Particles

(2011) Carlee E. Ashley et al.   ACS Nano

Generating enveloped virus-like particles with in vitro assembled cores

(2011) Fan Cheng et al.   VIROLOGY

Immunogenicity and safety of virus-like particle of the porcine encephalomyocarditis virus in pig

(2011) Hye-Young Jeoung et al.   Virology Journal

Directed Self-Assembly of Nanoparticles

(2010) Marek Grzelczak et al.   ACS Nano

Materials for Pharmaceutical Dosage Forms: Molecular Pharmaceutics and Controlled Release Drug Delivery Aspects

(2010) Heidi M. Mansour et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Self-Assembling Viral Mimetics: One Long Journey with Short Steps

(2010) Baptiste Lamarre et al.   MACROMOLECULAR BIOSCIENCE

Virus engineering: functionalization and stabilization

(2010) M. G. Mateu   PROTEIN ENGINEERING DESIGN & SELECTION

Assembly of Hybrid Bacteriophage Qβ Virus-like Particles

(2009) Steven D. Brown et al.   BIOCHEMISTRY

Progress and prospects: immune responses to viral vectors

(2009) S Nayak et al.   GENE THERAPY

Therapeutic manipulation of immune tolerance in allergic disease

(2009) Mübeccel Akdis et al.   NATURE REVIEWS DRUG DISCOVERY

Therapeutic Nanoparticles for Drug Delivery in Cancer

(2008) K. Cho et al.   CLINICAL CANCER RESEARCH

Electrophoretic Separation of Proteins

(2008) Bulbul Chakavarti et al.   Jove-Journal of Visualized Experiments