Review: A systematic review of virus-like particles of coronavirus: Assembly, generation, chimerism and their application in basic research and in the clinic

A stable platform for the production of virus-like particles pseudotyped with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike protein

(2021) Roy Sylvie et al.   VIRUS RESEARCH

A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses

(2021) Tiong Kit Tan et al.   Nature Communications

RNA-assisted self-assembly of monomeric antigens into virus-like particles as a recombinant vaccine platform

(2021) Beom Jeung Hwang et al.   BIOMATERIALS

Virus-like particles: preparation, immunogenicity and their roles as nanovaccines and drug nanocarriers

(2021) Saghi Nooraei et al.   JOURNAL OF NANOBIOTECHNOLOGY

Targets and strategies for vaccine development against SARS-CoV-2

(2021) Jonaid Ahmad Malik et al.   BIOMEDICINE & PHARMACOTHERAPY

Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses

(2021) Kevin O. Saunders et al.   NATURE

Protein-based antigen presentation platforms for nanoparticle vaccines

(2021) Brian Nguyen et al.   npj Vaccines

The roles of two major domains of the porcine deltacoronavirus spike subunit 1 in receptor binding and neutralization

(2021) Yan Liu et al.   JOURNAL OF VIROLOGY

Counting on COVID-19 Vaccine: Insights into the Current Strategies, Progress and Future Challenges

(2021) Ramesh Kandimalla et al.   Biomedicines

A Novel Coronavirus from Patients with Pneumonia in China, 2019

(2020) Na Zhu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Synthesis and Assembly of Hepatitis B Virus-Like Particles in a Pichia pastoris Cell-Free System

(2020) Alex J. Spice et al.   Frontiers in Bioengineering and Biotechnology

Real-time RT-PCR in COVID-19 detection: issues affecting the results

(2020) Alireza Tahamtan et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Potential Applications of Plant Biotechnology against SARS-CoV-2

(2020) Teresa Capell et al.   TRENDS IN PLANT SCIENCE

Chimeric Newcastle Disease Virus-like Particles Containing DC-Binding Peptide-Fused Haemagglutinin Protect Chickens from Virulent Newcastle Disease Virus and H9N2 Avian Influenza Virus Challenge

(2020) Xiaohong Xu et al.   VIROLOGICA SINICA

Swine enteric alphacoronavirus (swine acute diarrhea syndrome coronavirus): An update three years after its discovery

(2020) Yong-Le Yang et al.   VIRUS RESEARCH

Update on possible animal sources for COVID‐19 in humans

(2020) Tanja Opriessnig et al.   XENOTRANSPLANTATION

Comparative analysis of primer-probe sets for RT-qPCR of COVID-19 causative virus (SARS-CoV-2)

(2020) Yujin Jung et al.   ACS Infectious Diseases

Construction of SARS-CoV-2 Virus-Like Particles by Mammalian Expression System

(2020) Ruodan Xu et al.   Frontiers in Bioengineering and Biotechnology

Overcoming Symmetry Mismatch in Vaccine Nanoassembly via Spontaneous Amidation

(2020) Mark Howarth et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A role for Biofoundries in rapid development and validation of automated SARS-CoV-2 clinical diagnostics

(2020) Michael A. Crone et al.   Nature Communications

Biomimetic Virus-Like Particles as Severe Acute Respiratory Syndrome Coronavirus 2 Diagnostic Tools

(2020) Soo Khim Chan et al.   ACS Nano

Synthetic biology for bioengineering virus-like particle vaccines

(2019) Hayley K. Charlton Hume et al.   BIOTECHNOLOGY AND BIOENGINEERING

Broad cross-species infection of cultured cells by the bat HKU2-related swine acute diarrhea syndrome coronavirus (SADS-CoV) and identification of its replication in murine dendritic cells in vivo highlight its potential for diverse interspecies transmission

(2019) Yong-Le Yang et al.   JOURNAL OF VIROLOGY

Engineering a Rugged Nanoscaffold to Enhance Plug-and-Display Vaccination

(2018) Theodora Ulli Jordanka Bruun et al.   ACS Nano

Hepatitis B core antigen based novel vaccine against porcine epidemic diarrhea virus

(2018) Frank Gillam et al.   JOURNAL OF VIROLOGICAL METHODS

Epitope selection and their placement for increased virus neutralization in a novel vaccination strategy for porcine epidemic diarrhea virus utilizing the Hepatitis B virus core antigen

(2018) Frank Gillam et al.   VACCINE

A mouse model with age-dependent immune response and immune-tolerance for HBV infection

(2018) Xuerui Yi et al.   VACCINE

Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2

(2018) Wenfei Song et al.   PLoS Pathogens

Influenza virus-like particles harboring H9N2 HA and NA proteins induce a protective immune response in chicken

(2017) Xin Li et al.   Influenza and Other Respiratory Viruses

Production of virus-like particles for vaccines

(2017) J. Fuenmayor et al.   New Biotechnology

Major findings and recent advances in virus–like particle (VLP)-based vaccines

(2017) Mona O. Mohsen et al.   SEMINARS IN IMMUNOLOGY

Porcine epidemic diarrhea virus virus-like particles produced in insect cells induce specific immune responses in mice

(2017) Cuiling Wang et al.   VIRUS GENES

Virus like particles as a platform for cancer vaccine development

(2017) Hui Kian Ong et al.   PeerJ

Escherichia coli-derived virus-like particles in vaccine development

(2017) Xiaofen Huang et al.   npj Vaccines

Virus-like particles as drug delivery vectors

(2016) Michał Zdanowicz et al.   ACTA BIOCHIMICA POLONICA

Design of a hyperstable 60-subunit protein icosahedron

(2016) Yang Hsia et al.   NATURE

MERS-CoV virus-like particles produced in insect cells induce specific humoural and cellular imminity in rhesus macaques

(2016) Chong Wang et al.   Oncotarget

Bioengineering of Tobacco Mosaic Virus to Create a Non-Infectious Positive Control for Ebola Diagnostic Assays

(2016) Patricia Lam et al.   Scientific Reports

Cross host transmission in the emergence of MERS coronavirus

(2016) Chantal BEM Reusken et al.   Current Opinion in Virology

Self-assembling protein nanoparticles in the design of vaccines

(2016) Jacinto López-Sagaseta et al.   Computational and Structural Biotechnology Journal

Plug-and-Display: decoration of Virus-Like Particles via isopeptide bonds for modular immunization

(2016) Karl D. Brune et al.   Scientific Reports

Live attenuated and inactivated viral vaccine formulation and nasal delivery: Potential and challenges

(2015) José L. Tlaxca et al.   ADVANCED DRUG DELIVERY REVIEWS

The application of virus-like particles as vaccines and biological vehicles

(2015) Dan Yan et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Different applications of virus-like particles in biology and medicine: Vaccination and delivery systems

(2015) Zeinab Shirbaghaee et al.   BIOPOLYMERS

Assembly and immunogenicity of baculovirus-derived infectious bronchitis virus–like particles carrying membrane, envelope and the recombinant spike proteins

(2015) Peng-wei Xu et al.   BIOTECHNOLOGY LETTERS

Development of a non-infectious encapsidated positive control RNA for molecular assays to detect foot-and-mouth disease virus

(2015) Mikidache Madi et al.   JOURNAL OF VIROLOGICAL METHODS

Production and immunogenicity of chimeric virus-like particles containing the spike glycoprotein of infectious bronchitis virus

(2014) Lishan Lv et al.   Journal of Veterinary Science

Canine Parvovirus VP2 Protein Expressed in Silkworm Pupae Self-Assembles into Virus-Like Particles with High Immunogenicity

(2014) Hao Feng et al.   PLoS One

Palmitoylation of the Alphacoronavirus TGEV spike protein S is essential for incorporation into virus-like particles but dispensable for S–M interaction

(2014) Sandra Gelhaus et al.   VIROLOGY

Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Ion Channel Activity Promotes Virus Fitness and Pathogenesis

(2014) Jose L. Nieto-Torres et al.   PLoS Pathogens

Bioengineering virus-like particles as vaccines

(2013) Linda H.L. Lua et al.   BIOTECHNOLOGY AND BIOENGINEERING

Functional Analysis of the Murine Coronavirus Genomic RNA Packaging Signal

(2013) L. Kuo et al.   JOURNAL OF VIROLOGY

Identifying SARS-CoV Membrane Protein Amino Acid Residues Linked to Virus-Like Particle Assembly

(2013) Ying-Tzu Tseng et al.   PLoS One

A novel platform for virus-like particle-display of flaviviral envelope domain III: induction of Dengue and West Nile virus neutralizing antibodies

(2013) Anthony JS Chua et al.   Virology Journal

Porcine epidemic diarrhea virus E protein causes endoplasmic reticulum stress and up-regulates interleukin-8 expression

(2013) Xingang Xu et al.   Virology Journal

Mucosal Vaccine Design and Delivery

(2012) Kim A. Woodrow et al.   Annual Review of Biomedical Engineering

Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2012)

(2012) M. J. Adams et al.   ARCHIVES OF VIROLOGY

Two palmitylated cysteine residues of the severe acute respiratory syndrome coronavirus spike (S) protein are critical for S incorporation into virus-like particles, but not for M-S co-localization

(2012) M. Ujike et al.   JOURNAL OF GENERAL VIROLOGY

Discovery of Seven Novel Mammalian and Avian Coronaviruses in the Genus Deltacoronavirus Supports Bat Coronaviruses as the Gene Source of Alphacoronavirus and Betacoronavirus and Avian Coronaviruses as the Gene Source of Gammacoronavirus and Deltacoronavirus

(2012) P. C. Y. Woo et al.   JOURNAL OF VIROLOGY

Construction and Characterization of Virus-Like Particles: A Review

(2012) Andris Zeltins   MOLECULAR BIOTECHNOLOGY

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

(2012) Ali M. Zaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Merck Ad5/HIV induces broad innate immune activation that predicts CD8+ T-cell responses but is attenuated by preexisting Ad5 immunity

(2012) D. E. Zak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virus-like particles as a highly efficient vaccine platform: Diversity of targets and production systems and advances in clinical development

(2012) Natasha Kushnir et al.   VACCINE

Coronavirus E protein forms ion channels with functionally and structurally-involved membrane lipids

(2012) Carmina Verdiá-Báguena et al.   VIROLOGY

Identification of a conserved linear B-cell epitope in the M protein of porcine epidemic diarrhea virus

(2012) Zhibang Zhang et al.   Virology Journal

Mechanisms of Coronavirus Cell Entry Mediated by the Viral Spike Protein

(2012) Sandrine Belouzard et al.   Viruses-Basel

Cell-free protein synthesis: Applications come of age

(2011) Erik D. Carlson et al.   BIOTECHNOLOGY ADVANCES

Virus-Like Particle Vaccine Containing Hemagglutinin Confers Protection against 2009 H1N1 Pandemic Influenza

(2011) M. Jaber Hossain et al.   Clinical and Vaccine Immunology

Chimeric severe acute respiratory syndrome coronavirus (SARS-CoV) S glycoprotein and influenza matrix 1 efficiently form virus-like particles (VLPs) that protect mice against challenge with SARS-CoV

(2011) Ye V. Liu et al.   VACCINE

Self-assembly of Severe Acute Respiratory Syndrome Coronavirus Membrane Protein

(2010) Ying-Tzu Tseng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A structural analysis of M protein in coronavirus assembly and morphology

(2010) Benjamin W. Neuman et al.   JOURNAL OF STRUCTURAL BIOLOGY

A Conserved Domain in the Coronavirus Membrane Protein Tail Is Important for Virus Assembly

(2010) A. L. Arndt et al.   JOURNAL OF VIROLOGY

Emerging trends in plasma-free manufacturing of recombinant protein therapeutics expressed in mammalian cells

(2009) Leopold Grillberger et al.   Biotechnology Journal

The Many Pathways of RNA Degradation

(2009) Jonathan Houseley et al.   CELL

Identification of In Vivo-Interacting Domains of the Murine Coronavirus Nucleocapsid Protein

(2009) K. R. Hurst et al.   JOURNAL OF VIROLOGY

Virus-Like Particle Vaccine Comprised of the HA, NA, and M1 Proteins of an Avian Isolated H5N1 Influenza Virus Induces Protective Immunity Against Homologous and Heterologous Strains in Mice

(2009) Pan Tao et al.   VIRAL IMMUNOLOGY

Recent progress in the development of plant derived vaccines

(2008) Vidadi Yusibov et al.   Expert Review of Vaccines

Severe acute respiratory syndrome coronavirus nucleocapsid protein confers ability to efficiently produce virus-like particles when substituted for the human immunodeficiency virus nucleocapsid domain

(2008) Shui-Mei Wang et al.   JOURNAL OF BIOMEDICAL SCIENCE

The M, E, and N Structural Proteins of the Severe Acute Respiratory Syndrome Coronavirus Are Required for Efficient Assembly, Trafficking, and Release of Virus-Like Particles

(2008) Y. L. Siu et al.   JOURNAL OF VIROLOGY

Analysis of severe acute respiratory syndrome coronavirus structural proteins in virus-like particle assembly

(2008) Mina Nakauchi et al.   MICROBIOLOGY AND IMMUNOLOGY

Virus-Like Particles of SARS-Like Coronavirus Formed by Membrane Proteins from Different Origins Demonstrate Stimulating Activity in Human Dendritic Cells

(2008) Bingke Bai et al.   PLoS One

Chimeric coronavirus-like particles carrying severe acute respiratory syndrome coronavirus (SCoV) S protein protect mice against challenge with SCoV

(2008) Kumari G. Lokugamage et al.   VACCINE

Dissection and identification of regions required to form pseudoparticles by the interaction between the nucleocapsid (N) and membrane (M) proteins of SARS coronavirus

(2008) Seisuke Hatakeyama et al.   VIROLOGY