Metabolic regulation of somatic stem cells in vivo

Chaperone-mediated autophagy sustains haematopoietic stem-cell function

(2021) Shuxian Dong et al.   NATURE

NAD+ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle

(2021) Mario Romani et al.   Cell Reports

Metabolomic profiling of rare cell populations isolated by flow cytometry from tissues

(2021) Andrew W DeVilbiss et al.   eLife

Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth

(2021) Abigail S. Krall et al.   Cell Metabolism

Protein S-nitrosylation regulates proteostasis and viability of hematopoietic stem cell during regeneration

(2021) Weiwei Yi et al.   Cell Reports

The requirement for pyruvate dehydrogenase in leukemogenesis depends on cell lineage

(2021) Sojeong Jun et al.   Cell Metabolism

TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate

(2021) Laura García-Prat et al.   Cell Stem Cell

Niches that regulate stem cells and hematopoiesis in adult bone marrow

(2021) Stefano Comazzetto et al.   DEVELOPMENTAL CELL

Obesity accelerates hair thinning by stem cell-centric converging mechanisms

(2021) Hironobu Morinaga et al.   NATURE

Stable isotope tracing to assess tumor metabolism in vivo

(2021) Brandon Faubert et al.   Nature Protocols

High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity

(2021) Miyeko D. Mana et al.   Cell Reports

Nutrients in the fate of pluripotent stem cells

(2021) Vivian Lu et al.   Cell Metabolism

Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration

(2021) Le Qi et al.   Cell Stem Cell

Restraining Lysosomal Activity Preserves Hematopoietic Stem Cell Quiescence and Potency

(2020) Raymond Liang et al.   Cell Stem Cell

Asymmetrically Segregated Mitochondria Provide Cellular Memory of Hematopoietic Stem Cell Replicative History and Drive HSC Attrition

(2020) Ashwini Hinge et al.   Cell Stem Cell

New aspects of vitamin D metabolism and action — addressing the skin as source and target

(2020) Daniel Bikle et al.   Nature Reviews Endocrinology

Mitochondrial TCA cycle metabolites control physiology and disease

(2020) Inmaculada Martínez-Reyes et al.   Nature Communications

Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal

(2020) Lorena Hidalgo San Jose et al.   Cell Reports

Autophagy and Stem Cells: Self-Eating for Self-Renewal

(2020) Natasha C. Chang   Frontiers in Cell and Developmental Biology

Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy

(2020) Eija Pirinen et al.   Cell Metabolism

FASN-Dependent Lipid Metabolism Links Neurogenic Stem/Progenitor Cell Activity to Learning and Memory Deficits

(2020) Megan Bowers et al.   Cell Stem Cell

Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair

(2020) Brett A. Shook et al.   Cell Stem Cell

Essential role for autophagy protein ATG7 in the maintenance of intestinal stem cell integrity

(2020) Coralie Trentesaux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TET-family dioxygenases and the TET activator Vitamin C in immune responses and cancer

(2020) Xiaojing Yue et al.   BLOOD

An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells

(2020) Ekaterina V. Vinogradova et al.   CELL

Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance

(2020) Nick van Gastel et al.   Cell Metabolism

Mitochondria regulate intestinal stem cell proliferation and epithelial homeostasis through FOXO

(2020) Fan Zhang et al.   MOLECULAR BIOLOGY OF THE CELL

Bone marrow regeneration requires mitochondrial transfer from donor Cx43-expressing hematopoietic progenitors to stroma

(2020) Karin Golan et al.   BLOOD

Mitochondrial Potentiation Ameliorates Age-Related Heterogeneity in Hematopoietic Stem Cell Function

(2020) Els Mansell et al.   Cell Stem Cell

Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans

(2020) Felix A. Dingler et al.   MOLECULAR CELL

NAD+ metabolism and its roles in cellular processes during ageing

(2020) Anthony J. Covarrubias et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases

(2019) Antonio Cuadrado et al.   NATURE REVIEWS DRUG DISCOVERY

The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance

(2019) Nicola Vannini et al.   Cell Stem Cell

FXR Regulates Intestinal Cancer Stem Cell Proliferation

(2019) Ting Fu et al.   CELL

Retinoic acid signaling pathways

(2019) Norbert B. Ghyselinck et al.   DEVELOPMENT

Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function

(2019) Will Bailis et al.   NATURE

Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation

(2019) Zhimin Gu et al.   Cancer Discovery

Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function

(2019) Nora Yucel et al.   Cell Reports

The Bone Marrow Protects and Optimizes Immunological Memory during Dietary Restriction

(2019) Nicholas Collins et al.   CELL

Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet

(2019) Chia-Wei Cheng et al.   CELL

Asymmetric lysosome inheritance predicts activation of haematopoietic stem cells

(2019) Dirk Loeffler et al.   NATURE

Neural stem cell temporal patterning and brain tumour growth rely on oxidative phosphorylation

(2019) Jelle van den Ameele et al.   eLife

Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal

(2019) Stephanie Z. Xie et al.   Cell Stem Cell

Roles of vitamins in stem cells

(2019) Carlos Godoy-Parejo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

ROS-mediated PI3K activation drives mitochondrial transfer from stromal cells to hematopoietic stem cells in response to infection

(2019) Jayna J. Mistry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clonal hematopoiesis in human aging and disease

(2019) Siddhartha Jaiswal et al.   SCIENCE

The Rise of Physiologic Media

(2019) Jason R. Cantor   TRENDS IN CELL BIOLOGY

2-Oxoglutarate-Dependent Oxygenases

(2018) Md. Saiful Islam et al.   Annual Review of Biochemistry

Applications of metabolomics to study cancer metabolism

(2018) Akash K. Kaushik et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Metabolomics and Isotope Tracing

(2018) Cholsoon Jang et al.   CELL

Phospholipid Remodeling and Cholesterol Availability Regulate Intestinal Stemness and Tumorigenesis

(2018) Bo Wang et al.   Cell Stem Cell

Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging

(2018) Maria M. Mihaylova et al.   Cell Stem Cell

Branched-chain amino acid depletion conditions bone marrow for hematopoietic stem cell transplantation avoiding amino acid imbalance-associated toxicity

(2018) Adam C. Wilkinson et al.   EXPERIMENTAL HEMATOLOGY

Combinatorial CRISPR-Cas9 Metabolic Screens Reveal Critical Redox Control Points Dependent on the KEAP1-NRF2 Regulatory Axis

(2018) Dongxin Zhao et al.   MOLECULAR CELL

Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours

(2018) Javier Garcia-Bermudez et al.   NATURE CELL BIOLOGY

Aspartate is an endogenous metabolic limitation for tumour growth

(2018) Lucas B. Sullivan et al.   NATURE CELL BIOLOGY

Regulation of chromatin and gene expression by metabolic enzymes and metabolites

(2018) Xinjian Li et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The coming of age of chaperone-mediated autophagy

(2018) Susmita Kaushik et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging

(2018) Dena S. Leeman et al.   SCIENCE

ROS signalling in the biology of cancer

(2018) Jennifer N. Moloney et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting

(2018) H. Furkan Alkan et al.   Cell Metabolism

Integrated Stress Response Activity Marks Stem Cells in Normal Hematopoiesis and Leukemia

(2018) Peter van Galen et al.   Cell Reports

The hypoxia-inducible factors HIF1α and HIF2α are dispensable for embryonic muscle development but essential for postnatal muscle regeneration

(2017) Xin Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

27-Hydroxycholesterol induces hematopoietic stem cell mobilization and extramedullary hematopoiesis during pregnancy

(2017) Hideyuki Oguro et al.   JOURNAL OF CLINICAL INVESTIGATION

Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions

(2017) Amelie V. Guitart et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Autophagy maintains the metabolism and function of young and old stem cells

(2017) Theodore T. Ho et al.   NATURE

Cancer progression by reprogrammed BCAA metabolism in myeloid leukaemia

(2017) Ayuna Hattori et al.   NATURE

Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism

(2017) Guillermo Burgos-Barragan et al.   NATURE

Ascorbate regulates haematopoietic stem cell function and leukaemogenesis

(2017) Michalis Agathocleous et al.   NATURE

BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation

(2017) Simon Raffel et al.   NATURE

Interplay between metabolic identities in the intestinal crypt supports stem cell function

(2017) Maria J. Rodríguez-Colman et al.   NATURE

Lactate dehydrogenase activity drives hair follicle stem cell activation

(2017) Aimee Flores et al.   NATURE CELL BIOLOGY

The mitochondrial respiratory chain is essential for haematopoietic stem cell function

(2017) Elena Ansó et al.   NATURE CELL BIOLOGY

Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism

(2017) John C. Schell et al.   NATURE CELL BIOLOGY

Bone marrow adipocytes promote the regeneration of stem cells and haematopoiesis by secreting SCF

(2017) Bo O. Zhou et al.   NATURE CELL BIOLOGY

Role of Mitochondrial Metabolism in the Control of Early Lineage Progression and Aging Phenotypes in Adult Hippocampal Neurogenesis

(2017) Ruth Beckervordersandforth et al.   NEURON

Caloric Restriction Promotes Structural and Metabolic Changes in the Skin

(2017) Maria Fernanda Forni et al.   Cell Reports

Intrinsic Autophagy Is Required for the Maintenance of Intestinal Stem Cells and for Irradiation-Induced Intestinal Regeneration

(2017) Jumpei Asano et al.   Cell Reports

A Fatty Acid Oxidation-Dependent Metabolic Shift Regulates Adult Neural Stem Cell Activity

(2017) Marlen Knobloch et al.   Cell Reports

Adult hematopoietic stem cells lacking Hif-1  self-renew normally

(2016) M. Vukovic et al.   BLOOD

mTORC1 and SIRT1 Cooperate to Foster Expansion of Gut Adult Stem Cells during Calorie Restriction

(2016) Masaki Igarashi et al.   CELL

Cellular Metabolism and Induced Pluripotency

(2016) Jun Wu et al.   CELL

Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin

(2016) Dan Y. Gui et al.   Cell Metabolism

Phosphorylation of eIF2α Is a Translational Control Mechanism Regulating Muscle Stem Cell Quiescence and Self-Renewal

(2016) Victoria Zismanov et al.   Cell Stem Cell

Bile Acids Protect Expanding Hematopoietic Stem Cells from Unfolded Protein Stress in Fetal Liver

(2016) Valgardur Sigurdsson et al.   Cell Stem Cell

DNA Damage-Induced HSPC Malfunction Depends on ROS Accumulation Downstream of IFN-1 Signaling and Bid Mobilization

(2016) Alpaslan Tasdogan et al.   Cell Stem Cell

p38α Activates Purine Metabolism to Initiate Hematopoietic Stem/Progenitor Cell Cycling in Response to Stress

(2016) Daiki Karigane et al.   Cell Stem Cell

Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program

(2016) Mireille Khacho et al.   Cell Stem Cell

Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis

(2016) Christian Lange et al.   EMBO JOURNAL

The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs

(2016) Robert A.J. Signer et al.   GENES & DEVELOPMENT

Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential

(2016) Larry L. Luchsinger et al.   NATURE

Stem cell function and stress response are controlled by protein synthesis

(2016) Sandra Blanco et al.   NATURE

High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

(2016) Semir Beyaz et al.   NATURE

Autophagy maintains stemness by preventing senescence

(2016) Laura García-Prat et al.   NATURE

Metabolic regulation of gene expression through histone acylations

(2016) Benjamin R. Sabari et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

(2016) H. Zhang et al.   SCIENCE

Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantation

(2016) Y. Taya et al.   SCIENCE

Sensitivity of hematopoietic stem cells to mitochondrial dysfunction by SdhD gene deletion

(2016) José Antonio Bejarano-García et al.   Cell Death & Disease

A Comprehensive Review on l-Asparaginase and Its Applications

(2015) Tahira Batool et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Autophagy is required for stem cell mobilization by G-CSF

(2015) L. Leveque-El Mouttie et al.   BLOOD

Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock

(2015) Charlie R. Mantel et al.   CELL

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

(2015) Kıvanç Birsoy et al.   CELL

Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells

(2015) Lucas B. Sullivan et al.   CELL

Glycolysis-Mediated Changes in Acetyl-CoA and Histone Acetylation Control the Early Differentiation of Embryonic Stem Cells

(2015) Arieh Moussaieff et al.   Cell Metabolism

The NAD+-Dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells

(2015) James G. Ryall et al.   Cell Stem Cell

Single-Cell Transcriptomics Reveals a Population of Dormant Neural Stem Cells that Become Activated upon Brain Injury

(2015) Enric Llorens-Bobadilla et al.   Cell Stem Cell

Mitochondrial Function in Murine Skin Epithelium Is Crucial for Hair Follicle Morphogenesis and Epithelial–Mesenchymal Interactions

(2015) Jennifer E. Kloepper et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen

(2015) Lucas B. Pontel et al.   MOLECULAR CELL

Redox regulation of FoxO transcription factors

(2015) Lars-Oliver Klotz et al.   Redox Biology

Antioxidant N-acetyl-L-cysteine increases engraftment of human hematopoietic stem cells in immune-deficient mice

(2014) L. Hu et al.   BLOOD

Vitamin D is a determinant of mouse intestinal Lgr5 stem cell functions

(2014) Karina Peregrina et al.   CARCINOGENESIS

Ecdysone and Mediator Change Energy Metabolism to Terminate Proliferation in Drosophila Neural Stem Cells

(2014) Catarina C.F. Homem et al.   CELL

Cell-State-Specific Metabolic Dependency in Hematopoiesis and Leukemogenesis

(2014) Ying-Hua Wang et al.   CELL

Cellular Differences in Protein Synthesis Regulate Tissue Homeostasis

(2014) Michael Buszczak et al.   CELL

Methionine Metabolism Regulates Maintenance and Differentiation of Human Pluripotent Stem Cells

(2014) Nobuaki Shiraki et al.   Cell Metabolism

Prolonged Fasting Reduces IGF-1/PKA to Promote Hematopoietic-Stem-Cell-Based Regeneration and Reverse Immunosuppression

(2014) Chia-Wei Cheng et al.   Cell Stem Cell

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Induction of autophagy supports the bioenergetic demands of quiescent muscle stem cell activation

(2014) Ann H Tang et al.   EMBO JOURNAL

Metabolic regulation of stem cell function

(2014) R. J. Burgess et al.   JOURNAL OF INTERNAL MEDICINE

Mercaptopurine/Methotrexate Maintenance Therapy of Childhood Acute Lymphoblastic Leukemia

(2014) Kjeld Schmiegelow et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Direct measurement of local oxygen concentration in the bone marrow of live animals

(2014) Joel A. Spencer et al.   NATURE

Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells

(2014) Bryce W. Carey et al.   NATURE

The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress

(2014) Peter van Galen et al.   NATURE

mTORC1 controls the adaptive transition of quiescent stem cells from G0 to GAlert

(2014) Joseph T. Rodgers et al.   NATURE

Haematopoietic stem cells require a highly regulated protein synthesis rate

(2014) Robert A. J. Signer et al.   NATURE

Oestrogen increases haematopoietic stem-cell self-renewal in females and during pregnancy

(2014) Daisuke Nakada et al.   NATURE

Cellular mechanisms and physiological consequences of redox-dependent signalling

(2014) Kira M. Holmström et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lkb1 Is Indispensable for Skeletal Muscle Development, Regeneration, and Satellite Cell Homeostasis

(2014) Tizhong Shan et al.   STEM CELLS

Dppa5 Improves Hematopoietic Stem Cell Activity by Reducing Endoplasmic Reticulum Stress

(2014) Kenichi Miharada et al.   Cell Reports

Vitamin D and colon cancer

(2014) Lidija Klampfer   World Journal of Gastrointestinal Oncology

Hif-2  is not essential for cell-autonomous hematopoietic stem cell maintenance

(2013) A. V. Guitart et al.   BLOOD

Mechanisms that Regulate Stem Cell Aging and Life Span

(2013) Robert A.J. Signer et al.   Cell Stem Cell

Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells

(2013) Keiyo Takubo et al.   Cell Stem Cell

Metabolic Regulation by the Mitochondrial Phosphatase PTPMT1 Is Required for Hematopoietic Stem Cell Differentiation

(2013) Wen-Mei Yu et al.   Cell Stem Cell

FoxO3 coordinates metabolic pathways to maintain redox balance in neural stem cells

(2013) Hyeonju Yeo et al.   EMBO JOURNAL

The Lin28b–let-7–Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells

(2013) Michael R. Copley et al.   NATURE CELL BIOLOGY

Quantitative imaging of haematopoietic stem and progenitor cell localization and hypoxic status in the bone marrow microenvironment

(2013) César Nombela-Arrieta et al.   NATURE CELL BIOLOGY

Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development

(2013) R. B. Hamanaka et al.   Science Signaling

ER Stress Causes Rapid Loss of Intestinal Epithelial Stemness through Activation of the Unfolded Protein Response

(2013) Jarom Heijmans et al.   Cell Reports

Short-Term Calorie Restriction Enhances Skeletal Muscle Stem Cell Function

(2012) Massimiliano Cerletti et al.   Cell Stem Cell

Pten Deletion in Adult Hippocampal Neural Stem/Progenitor Cells Causes Cellular Abnormalities and Alters Neurogenesis

(2012) A. Amiri et al.   JOURNAL OF NEUROSCIENCE

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

(2012) Marlen Knobloch et al.   NATURE

Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function

(2012) Juan I. Garaycoechea et al.   NATURE

mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake

(2012) Ömer H. Yilmaz et al.   NATURE

Metabolic differentiation in the embryonic retina

(2012) Michalis Agathocleous et al.   NATURE CELL BIOLOGY

A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance

(2012) Keisuke Ito et al.   NATURE MEDICINE

Influence of Threonine Metabolism on S-Adenosylmethionine and Histone Methylation

(2012) N. Shyh-Chang et al.   SCIENCE

Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells

(2011) T. Yahata et al.   BLOOD

In Vivo Clonal Analysis Reveals Self-Renewing and Multipotent Adult Neural Stem Cell Characteristics

(2011) Michael A. Bonaguidi et al.   CELL

Accumulating Mitochondrial DNA Mutations Drive Premature Hematopoietic Aging Phenotypes Distinct from Physiological Stem Cell Aging

(2011) Gudmundur L. Norddahl et al.   Cell Stem Cell

Redox Regulation by Keap1 and Nrf2 Controls Intestinal Stem Cell Proliferation in Drosophila

(2011) Christine E. Hochmuth et al.   Cell Stem Cell

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

(2011) Monika Mortensen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice

(2011) Frédéric Langevin et al.   NATURE

Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway

(2011) Ivan V Rosado et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche

(2010) Tugba Simsek et al.   Cell Stem Cell

Specific roles of Target of rapamycin in the control of stem cells and their progeny in the Drosophila ovary

(2010) L. LaFever et al.   DEVELOPMENT

Mitochondrial respiration defects modulate differentiation but not proliferation of hematopoietic stem and progenitor cells

(2010) Shin-Ichi Inoue et al.   FEBS LETTERS

Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells

(2010) Daisuke Nakada et al.   NATURE

The Lkb1 metabolic sensor maintains haematopoietic stem cell survival

(2010) Sushma Gurumurthy et al.   NATURE

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells

(2010) Boyi Gan et al.   NATURE

Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress

(2010) Sergei Chuikov et al.   NATURE CELL BIOLOGY

Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue

(2010) Sava Sakadžić et al.   NATURE METHODS

Mechanisms of Stem Cell Self-Renewal

(2009) He Shenghui et al.   Annual Review of Cell and Developmental Biology

FoxOs Cooperatively Regulate Diverse Pathways Governing Neural Stem Cell Homeostasis

(2009) Ji-hye Paik et al.   Cell Stem Cell

FoxO3 Regulates Neural Stem Cell Homeostasis

(2009) Valérie M. Renault et al.   Cell Stem Cell

ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation

(2009) K. E. Wellen et al.   SCIENCE

Hmga2 Promotes Neural Stem Cell Self-Renewal in Young but Not Old Mice by Reducing p16Ink4a and p19Arf Expression

(2008) Jinsuke Nishino et al.   CELL

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

(2008) Anne Wilson et al.   CELL

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

A Specialized Vascular Niche for Adult Neural Stem Cells

(2008) Masoud Tavazoie et al.   Cell Stem Cell

Adult SVZ Stem Cells Lie in a Vascular Niche: A Quantitative Analysis of Niche Cell-Cell Interactions

(2008) Qin Shen et al.   Cell Stem Cell

TSC–mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species

(2008) Chong Chen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Haematopoietic stem cell release is regulated by circadian oscillations

(2008) Simón Méndez-Ferrer et al.   NATURE

mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization

(2008) B. Gan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA