Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours

Aspartate is an endogenous metabolic limitation for tumour growth

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Structure and allosteric inhibition of excitatory amino acid transporter 1

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The Emerging Hallmarks of Cancer Metabolism

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Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors

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Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein

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An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

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Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells

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A roadmap for interpreting 13 C metabolite labeling patterns from cells

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Targeting mitochondria metabolism for cancer therapy

(2015) Samuel E Weinberg et al.   Nature Chemical Biology

Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides

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Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment

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Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR

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Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis

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Allosteric Modulation of an Excitatory Amino Acid Transporter: The Subtype-Selective Inhibitor UCPH-101 Exerts Sustained Inhibition of EAAT1 through an Intramonomeric Site in the Trimerization Domain

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The SLC1 high-affinity glutamate and neutral amino acid transporter family

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Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

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Mass spectrometry images acylcarnitines, phosphatidylcholines, and sphingomyelin in MDA-MB-231 breast tumor models

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

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Metabolic Profiling of Hypoxic Cells Revealed a Catabolic Signature Required for Cell Survival

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Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

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Targeting the hypoxia-inducible factor (HIF) pathway in cancer

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