Lkb1 Is Indispensable for Skeletal Muscle Development, Regeneration, and Satellite Cell Homeostasis

Marked phenotypic differences of endurance performance and exercise-induced oxygen consumption between AMPK and LKB1 deficiency in mouse skeletal muscle: changes occurring in the diaphragm

(2013) Shinji Miura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mitochondrial and performance adaptations to exercise training in mice lacking skeletal muscle LKB1

(2013) Colby B. Tanner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The LKB1-AMPK Pathway—Friend or Foe in Cancer?

(2013) D. Grahame Hardie   CANCER CELL

MyoD-expressing progenitors are essential for skeletal myogenesis and satellite cell development

(2013) William M. Wood et al.   DEVELOPMENTAL BIOLOGY

LKB1 Regulates Lipid Oxidation During Exercise Independently of AMPK

(2013) J. Jeppesen et al.   DIABETES

Myostatin knockout drives browning of white adipose tissue through activating the AMPK-PGC1α-Fndc5 pathway in muscle

(2013) Tizhong Shan et al.   FASEB JOURNAL

Lying low but ready for action: the quiescent muscle satellite cell

(2013) Didier Montarras et al.   FEBS Journal

Distinct populations of adipogenic and myogenic Myf5-lineage progenitors in white adipose tissues

(2013) Tizhong Shan et al.   JOURNAL OF LIPID RESEARCH

Lkb1/Stk11 regulation of mTOR signaling controls the transition of chondrocyte fates and suppresses skeletal tumor formation

(2013) L. P. Lai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Subpopulation of Adult Skeletal Muscle Stem Cells Retains All Template DNA Strands after Cell Division

(2012) Pierre Rocheteau et al.   CELL

Tissue-Specific Stem Cells: Lessons from the Skeletal Muscle Satellite Cell

(2012) Andrew S. Brack et al.   Cell Stem Cell

Hypoxia promotes satellite cell self-renewal and enhances the efficiency of myoblast transplantation

(2012) W. Liu et al.   DEVELOPMENT

Fatty acid binding protein 4 expression marks a population of adipocyte progenitors in white and brown adipose tissues

(2012) Tizhong Shan et al.   FASEB JOURNAL

Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways

(2012) Bryan Lo et al.   JOURNAL OF CELL BIOLOGY

Constitutive Notch Activation Upregulates Pax7 and Promotes the Self-Renewal of Skeletal Muscle Satellite Cells

(2012) Y. Wen et al.   MOLECULAR AND CELLULAR BIOLOGY

Programmed elimination of cells by caspase-independent cell extrusion in C. elegans

(2012) Daniel P. Denning et al.   NATURE

Maintenance of muscle stem-cell quiescence by microRNA-489

(2012) Tom H. Cheung et al.   NATURE

Regulation of SIK1 abundance and stability is critical for myogenesis

(2012) R. Stewart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt signaling in myogenesis

(2012) Julia von Maltzahn et al.   TRENDS IN CELL BIOLOGY

The Tumor Suppressor LKB1 Emerges as a Critical Factor in Hematopoietic Stem Cell Biology

(2011) Bryan Krock et al.   Cell Metabolism

Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration

(2011) M. M. Murphy et al.   DEVELOPMENT

Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration

(2011) R. Sambasivan et al.   DEVELOPMENT

An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration

(2011) C. Lepper et al.   DEVELOPMENT

A Critical Requirement for Notch Signaling in Maintenance of the Quiescent Skeletal Muscle Stem Cell State

(2011) Philippos Mourikis et al.   STEM CELLS

Notch Signaling Is Necessary to Maintain Quiescence in Adult Muscle Stem Cells

(2011) Christopher R.R. Bjornson et al.   STEM CELLS

Skeletal muscle dysfunction in muscle-specific LKB1 knockout mice

(2010) David M. Thomson et al.   JOURNAL OF APPLIED PHYSIOLOGY

LKB1-Mediated Spatial Control of GSK3  and Adenomatous Polyposis Coli Contributes to Centrosomal Forward Movement and Neuronal Migration in the Developing Neocortex

(2010) N. Asada et al.   JOURNAL OF NEUROSCIENCE

The blood balance

(2010) Ellen M. Durand et al.   NATURE

Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells

(2010) Daisuke Nakada et al.   NATURE

The Lkb1 metabolic sensor maintains haematopoietic stem cell survival

(2010) Sushma Gurumurthy et al.   NATURE

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells

(2010) Boyi Gan et al.   NATURE

LKB1 maintains the balance

(2010) Rachel David   NATURE REVIEWS MOLECULAR CELL BIOLOGY

LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling

(2010) Y. Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New Roles for the LKB1-NUAK Pathway in Controlling Myosin Phosphatase Complexes and Cell Adhesion

(2010) A. Zagorska et al.   Science Signaling

LKB1 Regulates Pancreatic β Cell Size, Polarity, and Function

(2009) Zvi Granot et al.   Cell Metabolism

Loss of Lkb1 in Adult β Cells Increases β Cell Mass and Enhances Glucose Tolerance in Mice

(2009) Accalia Fu et al.   Cell Metabolism

Progenitors of skeletal muscle satellite cells express the muscle determination gene, MyoD

(2009) Onur Kanisicak et al.   DEVELOPMENTAL BIOLOGY

LKB1 is essential for the proliferation of T-cell progenitors and mature peripheral T cells

(2009) Peter Tamás et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy

(2009) Valérie Risson et al.   JOURNAL OF CELL BIOLOGY

LKB1 regulates polarity remodeling and adherens junction formation in the Drosophila eye

(2009) N. Amin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-6 Is an Essential Regulator of Satellite Cell-Mediated Skeletal Muscle Hypertrophy

(2008) Antonio L. Serrano et al.   Cell Metabolism

Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy

(2008) C. Florian Bentzinger et al.   Cell Metabolism

A Temporal Switch from Notch to Wnt Signaling in Muscle Stem Cells Is Necessary for Normal Adult Myogenesis

(2008) Andrew S. Brack et al.   Cell Stem Cell

Niche Regulation of Muscle Satellite Cell Self-Renewal and Differentiation

(2008) Shihuan Kuang et al.   Cell Stem Cell

Pancreatic Lkb1 Deletion Leads to Acinar Polarity Defects and Cystic Neoplasms

(2008) A. F. Hezel et al.   MOLECULAR AND CELLULAR BIOLOGY

LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis

(2008) Pekka Katajisto et al.   NATURE GENETICS

The emerging biology of satellite cells and their therapeutic potential

(2008) Shihuan Kuang et al.   TRENDS IN MOLECULAR MEDICINE