Mitochondria regulate intestinal stem cell proliferation and epithelial homeostasis through FOXO

PINK1 Inhibits Local Protein Synthesis to Limit Transmission of Deleterious Mitochondrial DNA Mutations

(2019) Yi Zhang et al.   MOLECULAR CELL

Mitochondria and the dynamic control of stem cell homeostasis

(2018) Pawel Lisowski et al.   EMBO REPORTS

Autophagy suppresses Ras-driven epithelial tumourigenesis by limiting the accumulation of reactive oxygen species

(2017) J Manent et al.   ONCOGENE

Loss of Parkinson’s disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c

(2017) Hongrui Meng et al.   Nature Communications

EGFR-dependent TOR-independent endocycles support Drosophila gut epithelial regeneration

(2017) Jinyi Xiang et al.   Nature Communications

PGAM5 promotes lasting FoxO activation after developmental mitochondrial stress and extends lifespan in Drosophila

(2017) Martin Borch Jensen et al.   eLife

RNA Interference Directed against theTransglutaminaseGene Triggers Dysbiosis of Gut Microbiota inDrosophila

(2016) Sanae Sekihara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation

(2016) Xinde Zheng et al.   eLife

In vivo genetic dissection of tumor growth and the Warburg effect

(2016) Cheng-Wei Wang et al.   eLife

The cAMP phosphodiesterase Prune localizes to the mitochondrial matrix and promotes mtDNA replication by stabilizing TFAM

(2015) F. Zhang et al.   EMBO REPORTS

Resistance of glia-like central and peripheral neural stem cells to genetically induced mitochondrial dysfunction--differential effects on neurogenesis

(2015) B. Diaz-Castro et al.   EMBO REPORTS

Genetic mosaic analysis of a deleterious mitochondrial DNA mutation in Drosophila reveals novel aspects of mitochondrial regulation and function

(2015) Zhe Chen et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular Architecture of 4E-BP Translational Inhibitors Bound to eIF4E

(2015) Daniel Peter et al.   MOLECULAR CELL

ATP synthase promotes germ cell differentiation independent of oxidative phosphorylation

(2015) Felipe K. Teixeira et al.   NATURE CELL BIOLOGY

Accumulation of differentiating intestinal stem cell progenies drives tumorigenesis

(2015) Zongzhao Zhai et al.   Nature Communications

Tie-mediated signal from apoptotic cells protects stem cells in Drosophila melanogaster

(2015) Yalan Xing et al.   Nature Communications

A Sox Transcription Factor Is a Critical Regulator of Adult Stem Cell Proliferation in the Drosophila Intestine

(2015) Fanju W. Meng et al.   Cell Reports

Redox regulation of FoxO transcription factors

(2015) Lars-Oliver Klotz et al.   Redox Biology

Mitochondrial remodeling in hepatic differentiation and dedifferentiation

(2014) Anaïs Wanet et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Forkhead Transcription Factor FOXO3a Levels Are Increased in Huntington Disease Because of Overactivated Positive Autofeedback Loop

(2014) Kaja Kannike et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective propagation of functional mitochondrial DNA during oogenesis restricts the transmission of a deleterious mitochondrial variant

(2014) Jahda H Hill et al.   NATURE GENETICS

Slit/Robo Signaling Regulates Cell Fate Decisions in the Intestinal Stem Cell Lineage of Drosophila

(2014) Benoît Biteau et al.   Cell Reports

Interplay of dFOXO and Two ETS-Family Transcription Factors Determines Lifespan in Drosophila melanogaster

(2014) Nazif Alic et al.   PLoS Genetics

Energy metabolism and energy-sensing pathways in mammalian embryonic and adult stem cell fate

(2013) V. A. Rafalski et al.   JOURNAL OF CELL SCIENCE

Molecular regulation of stem cell quiescence

(2013) Tom H. Cheung et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial Respiration Regulates Adipogenic Differentiation of Human Mesenchymal Stem Cells

(2013) Yanmin Zhang et al.   PLoS One

Induced Pluripotent Stem Cells with a Mitochondrial DNA Deletion

(2013) Anne B. C. Cherry et al.   STEM CELLS

Morphological and Molecular Characterization of Adult Midgut Compartmentalization in Drosophila

(2013) Nicolas Buchon et al.   Cell Reports

Survival Response to Increased Ceramide Involves Metabolic Adaptation through Novel Regulators of Glycolysis and Lipolysis

(2013) Niraj K. Nirala et al.   PLoS Genetics

Physiological and stem cell compartmentalization within the Drosophila midgut

(2013) Alexis Marianes et al.   eLife

Superoxide generation by complex III: From mechanistic rationales to functional consequences

(2012) Lea Bleier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Metabolic Plasticity in Stem Cell Homeostasis and Differentiation

(2012) Clifford D.L. Folmes et al.   Cell Stem Cell

Notch-Mediated Suppression of TSC2 Expression Regulates Cell Differentiation in the Drosophila Intestinal Stem Cell Lineage

(2012) Subir Kapuria et al.   PLoS Genetics

Redox Regulation by Keap1 and Nrf2 Controls Intestinal Stem Cell Proliferation in Drosophila

(2011) Christine E. Hochmuth et al.   Cell Stem Cell

Maintaining Tissue Homeostasis: Dynamic Control of Somatic Stem Cell Activity

(2011) Benoit Biteau et al.   Cell Stem Cell

Intestinal stem cells in the adult Drosophila midgut

(2011) Huaqi Jiang et al.   EXPERIMENTAL CELL RESEARCH

Quiescent gastric stem cells maintain the adult Drosophila stomach

(2011) M. Strand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Mitochondria in Reactive Oxygen Species Metabolism and Signaling

(2010) Anatoly A. Starkov   Annals of the New York Academy of Sciences

FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging

(2010) Fabio Demontis et al.   CELL

Mitochondrial respiration defects modulate differentiation but not proliferation of hematopoietic stem and progenitor cells

(2010) Shin-Ichi Inoue et al.   FEBS LETTERS

The Senescence-Related Mitochondrial/Oxidative Stress Pathway is Repressed in Human Induced Pluripotent Stem Cells

(2010) Alessandro Prigione et al.   STEM CELLS

Mitochondrial Function Controls Proliferation and Early Differentiation Potential of Embryonic Stem Cells

(2010) Sudip Mandal et al.   STEM CELLS

Cytokine/Jak/Stat Signaling Mediates Regeneration and Homeostasis in the Drosophila Midgut

(2009) Huaqi Jiang et al.   CELL

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Origins and evolution of the mechanisms regulating translation initiation in eukaryotes

(2009) Greco Hernández et al.   TRENDS IN BIOCHEMICAL SCIENCES

JNK Activity in Somatic Stem Cells Causes Loss of Tissue Homeostasis in the Aging Drosophila Gut

(2008) Benoît Biteau et al.   Cell Stem Cell

Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint

(2008) Edward Owusu-Ansah et al.   NATURE GENETICS

Manipulating the Metazoan Mitochondrial Genome with Targeted Restriction Enzymes

(2008) H. Xu et al.   SCIENCE