- Home
- Publications
- Publication Search
- Publication Details
Title
Nutrients in the fate of pluripotent stem cells
Authors
Keywords
nutrients, metabolism, pluripotent stem cell, fate, development, differentiation
Journal
Cell Metabolism
Volume 33, Issue 11, Pages 2108-2121
Publisher
Elsevier BV
Online
2021-10-13
DOI
10.1016/j.cmet.2021.09.013
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Formative pluripotent stem cells show features of epiblast cells poised for gastrulation
- (2021) Xiaoxiao Wang et al. CELL RESEARCH
- Regulation and metabolic functions of mTORC1 and mTORC2
- (2021) Angelia Szwed et al. PHYSIOLOGICAL REVIEWS
- PINK1‐mediated mitophagy maintains pluripotency through optineurin
- (2021) Chaoqun Wang et al. CELL PROLIFERATION
- Developments in pluripotency: a new formative state
- (2021) Stefan H. A. Hoogland et al. CELL RESEARCH
- Metabolic plasticity drives development during mammalian embryogenesis
- (2021) Mark S. Sharpley et al. DEVELOPMENTAL CELL
- Metabolic Control over mTOR-Dependent Diapause-like State
- (2020) Abdiasis M. Hussein et al. DEVELOPMENTAL CELL
- Energy Metabolism Regulates Stem Cell Pluripotency
- (2020) Enkhtuul Tsogtbaatar et al. Frontiers in Cell and Developmental Biology
- Glycolysis-Independent Glucose Metabolism Distinguishes TE from ICM Fate during Mammalian Embryogenesis
- (2020) Fangtao Chi et al. DEVELOPMENTAL CELL
- O-GlcNAcylation regulates the methionine cycle to promote pluripotency of stem cells
- (2020) Qiang Zhu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nutrient-Driven O-GlcNAcylation Controls DNA Damage Repair Signaling and Stem/Progenitor Cell Homeostasis
- (2020) Hyun-jin Na et al. Cell Reports
- Metabolic Coordination of Cell Fate by α-Ketoglutarate-Dependent Dioxygenases
- (2020) Sanjeethan C. Baksh et al. TRENDS IN CELL BIOLOGY
- Fatty Acid Synthesis Is Indispensable for Survival of Human Pluripotent Stem Cells
- (2020) Sho Tanosaki et al. iScience
- Derivation of Intermediate Pluripotent Stem Cells Amenable to Primordial Germ Cell Specification
- (2020) Leqian Yu et al. Cell Stem Cell
- Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency
- (2020) Masaki Kinoshita et al. Cell Stem Cell
- Mitochondrial metabolism and glutamine are essential for mesoderm differentiation of human pluripotent stem cells
- (2019) Vivian Lu et al. CELL RESEARCH
- Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs
- (2019) Daniela Cornacchia et al. Cell Stem Cell
- Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells
- (2019) Chengcheng Song et al. Stem Cell Reports
- Next-generation unnatural monosaccharides reveal that ESRRB O-GlcNAcylation regulates pluripotency of mouse embryonic stem cells
- (2019) Yi Hao et al. Nature Communications
- Metabolism in Pluripotent Stem Cells and Early Mammalian Development
- (2018) Jin Zhang et al. Cell Metabolism
- Lipid Supplement in the Cultural Condition Facilitates the Porcine iPSC Derivation through cAMP/PKA/CREB Signal Pathway
- (2018) Wei Zhang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- High Glucose Inhibits Neural Stem Cell Differentiation Through Oxidative Stress and Endoplasmic Reticulum Stress
- (2018) Xi Chen et al. STEM CELLS AND DEVELOPMENT
- Phosphorylation of ULK1 by AMPK is essential for mouse embryonic stem cell self-renewal and pluripotency
- (2018) Jiaqi Gong et al. Cell Death & Disease
- Mitochondrial and glycolytic remodeling during nascent neural differentiation of human pluripotent stem cells
- (2018) Jarmon G. Lees et al. DEVELOPMENT
- Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells
- (2018) Xiuying Zhong et al. Cell Metabolism
- Mechanisms regulating zygotic genome activation
- (2018) Katharine N. Schulz et al. NATURE REVIEWS GENETICS
- The metabolic programming of stem cells
- (2017) Ng Shyh-Chang et al. GENES & DEVELOPMENT
- O-GlcNAc transferase regulates transcriptional activity of human Oct4
- (2017) Sandii Constable et al. GLYCOBIOLOGY
- Nutrient-drivenO-linkedN-acetylglucosamine (O-GlcNAc) cycling impacts neurodevelopmental timing and metabolism
- (2017) Stephanie Olivier-Van Stichelen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Proteomic Analysis of Human Pluripotent Stem Cell Cardiomyogenesis Revealed Altered Expression of Metabolic Enzymes and PDLIM5 Isoforms
- (2017) Sarah A. Konze et al. JOURNAL OF PROTEOME RESEARCH
- Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK
- (2017) Chen-Song Zhang et al. NATURE
- SAMTOR is anS-adenosylmethionine sensor for the mTORC1 pathway
- (2017) Xin Gu et al. SCIENCE
- Biological Significance of the Suppression of Oxidative Phosphorylation in Induced Pluripotent Stem Cells
- (2017) Cheng Zhang et al. Cell Reports
- High glucose suppresses embryonic stem cell differentiation into neural lineage cells
- (2016) Penghua Yang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Vitamin C promotes pluripotency of human induced pluripotent stem cells via the histone demethylase JARID1A
- (2016) Wassim Eid et al. BIOLOGICAL CHEMISTRY
- The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway
- (2016) Lynne Chantranupong et al. CELL
- α-Ketoglutarate Accelerates the Initial Differentiation of Primed Human Pluripotent Stem Cells
- (2016) Tara TeSlaa et al. Cell Metabolism
- Glutamine Oxidation Is Indispensable for Survival of Human Pluripotent Stem Cells
- (2016) Shugo Tohyama et al. Cell Metabolism
- Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State
- (2016) Wen Gu et al. Cell Stem Cell
- AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes
- (2016) Nathan P. Young et al. GENES & DEVELOPMENT
- Regulation of amino acid transporters in pluripotent cell populations in the embryo and in culture; novel roles for sodium-coupled neutral amino acid transporters
- (2016) Boon Siang Nicholas Tan et al. MECHANISMS OF DEVELOPMENT
- Inhibition of mTOR induces a paused pluripotent state
- (2016) Aydan Bulut-Karslioglu et al. NATURE
- Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy
- (2016) Mahima Swamy et al. NATURE IMMUNOLOGY
- Autotaxin-mediated lipid signaling intersects with LIF and BMP signaling to promote the naive pluripotency transcription factor program
- (2016) Cody Kime et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CXCR2 Inhibition in Human Pluripotent Stem Cells Induces Predominant Differentiation to Mesoderm and Endoderm Through Repression of mTOR, β-Catenin, and hTERT Activities
- (2016) Ji-Hye Jung et al. STEM CELLS AND DEVELOPMENT
- Glutamine Metabolism Regulates the Pluripotency Transcription Factor OCT4
- (2016) Glenn Marsboom et al. Cell Reports
- Distinct Metabolic States Can Support Self-Renewal and Lipogenesis in Human Pluripotent Stem Cells under Different Culture Conditions
- (2016) Hui Zhang et al. Cell Reports
- SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells
- (2016) Samuel A Myers et al. eLife
- A Multi-Lineage Screen Reveals mTORC1 Inhibition Enhances Human Pluripotent Stem Cell Mesendoderm and Blood Progenitor Production
- (2016) Emanuel Joseph Paul Nazareth et al. Stem Cell Reports
- Nutrient shortage triggers the hexosamine biosynthetic pathway via the GCN2-ATF4 signalling pathway
- (2016) Cédric Chaveroux et al. Scientific Reports
- Glutamine contributes to maintenance of mouse embryonic stem cell self-renewal through PKC-dependent downregulation of HDAC1 and DNMT1/3a
- (2015) Jung Min Ryu et al. CELL CYCLE
- Glycolysis-Mediated Changes in Acetyl-CoA and Histone Acetylation Control the Early Differentiation of Embryonic Stem Cells
- (2015) Arieh Moussaieff et al. Cell Metabolism
- GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2
- (2015) Jiangbin Ye et al. GENES & DEVELOPMENT
- A little sugar goes a long way: The cell biology of O-GlcNAc
- (2015) Michelle R. Bond et al. JOURNAL OF CELL BIOLOGY
- Hallmarks of pluripotency
- (2015) Alejandro De Los Angeles et al. NATURE
- Dichloroacetate, the Pyruvate Dehydrogenase Complex and the Modulation of mESC Pluripotency
- (2015) Ana Sofia Rodrigues et al. PLoS One
- Blastocyst metabolism
- (2015) David K. Gardner et al. REPRODUCTION FERTILITY AND DEVELOPMENT
- Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1
- (2015) S. Wang et al. SCIENCE
- Sestrin2 is a leucine sensor for the mTORC1 pathway
- (2015) R. L. Wolfson et al. SCIENCE
- A Nuclear Pyruvate Dehydrogenase Complex Is Important for the Generation of Acetyl-CoA and Histone Acetylation
- (2014) Gopinath Sutendra et al. CELL
- Methionine Metabolism Regulates Maintenance and Differentiation of Human Pluripotent Stem Cells
- (2014) Nobuaki Shiraki et al. Cell Metabolism
- Regulatory Principles of Pluripotency: From the Ground State Up
- (2014) Jamie A. Hackett et al. Cell Stem Cell
- Quantitative proteomics analysis highlights the role of redox hemostasis and energy metabolism in human embryonic stem cell differentiation to neural cells
- (2014) Ali Fathi et al. Journal of Proteomics
- Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells
- (2014) Bryce W. Carey et al. NATURE
- UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation
- (2014) A. Vozza et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lipids and oocyte developmental competence: the role of fatty acids and β-oxidation
- (2014) Kylie R Dunning et al. REPRODUCTION
- ElevatedO-GlcNAc Levels Activate Epigenetically Repressed Genes and Delay Mouse ESC Differentiation Without Affecting Naïve to Primed Cell Transition
- (2014) Christopher M. Speakman et al. STEM CELLS
- The mitochondrial H+-ATP synthase and the lipogenic switch
- (2013) Alejandro Vazquez-Martin et al. CELL CYCLE
- AMP as a Low-Energy Charge Signal Autonomously Initiates Assembly of AXIN-AMPK-LKB1 Complex for AMPK Activation
- (2013) Ya-Lin Zhang et al. Cell Metabolism
- Stem cell metabolism in tissue development and aging
- (2013) N. Shyh-Chang et al. DEVELOPMENT
- Ten-Eleven Translocation 1 (Tet1) Is Regulated byO-LinkedN-Acetylglucosamine Transferase (Ogt) for Target Gene Repression in Mouse Embryonic Stem Cells
- (2013) Feng-Tao Shi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tet Proteins Connect the O-Linked N-acetylglucosamine Transferase Ogt to Chromatin in Embryonic Stem Cells
- (2013) Pietro Vella et al. MOLECULAR CELL
- Excess of O-linked N-acetylglucosamine modifies human pluripotent stem cell differentiation
- (2013) Julien Jean Pierre Maury et al. Stem Cell Research
- Regulation ofL-Threonine Dehydrogenase in Somatic Cell Reprogramming
- (2013) Chuanchun Han et al. STEM CELLS
- Autophagy Regulates Homeostasis of Pluripotency-Associated Proteins in hESCs
- (2013) Yun-Hee Cho et al. STEM CELLS
- Vitamin C Enhances Nanog Expression Via Activation of the JAK/STAT Signaling Pathway
- (2013) Haibo Wu et al. STEM CELLS
- O-GlcNAcase is essential for embryonic development and maintenance of genomic stability
- (2012) Yong Ryoul Yang et al. AGING CELL
- The transcriptional regulation of pluripotency
- (2012) Jia-Chi Yeo et al. CELL RESEARCH
- O-GlcNAc Regulates Pluripotency and Reprogramming by Directly Acting on Core Components of the Pluripotency Network
- (2012) Hyonchol Jang et al. Cell Stem Cell
- Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival
- (2012) Alejo Efeyan et al. NATURE
- Influence of Threonine Metabolism on S-Adenosylmethionine and Histone Methylation
- (2012) N. Shyh-Chang et al. SCIENCE
- The amino acid transporter SNAT2 mediates l-proline-induced differentiation of ES cells
- (2011) Boon Siang Nicholas Tan et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming
- (2011) Clifford D.L. Folmes et al. Cell Metabolism
- Ascorbic acid enhances the cardiac differentiation of induced pluripotent stem cells through promoting the proliferation of cardiac progenitor cells
- (2011) Nan Cao et al. CELL RESEARCH
- The Histone Demethylases Jhdm1a/1b Enhance Somatic Cell Reprogramming in a Vitamin-C-Dependent Manner
- (2011) Tao Wang et al. Cell Stem Cell
- UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells
- (2011) Jin Zhang et al. EMBO JOURNAL
- l-Threonine Regulates G1/S Phase Transition of Mouse Embryonic Stem Cells via PI3K/Akt, MAPKs, and mTORC Pathways
- (2011) Jung Min Ryu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
- (2011) Joungmok Kim et al. NATURE CELL BIOLOGY
- Energy Metabolism in Human Pluripotent Stem Cells and Their Differentiated Counterparts
- (2011) Sandra Varum et al. PLoS One
- Control of embryonic stem cell metastability by l-proline catabolism
- (2011) Laura Casalino et al. Journal of Molecular Cell Biology
- l-Proline induces differentiation of ES cells: a novel role for an amino acid in the regulation of pluripotent cells in culture
- (2010) Jennifer M. Washington et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Beta-Oxidation Is Essential for Mouse Oocyte Developmental Competence and Early Embryo Development1
- (2010) Kylie R. Dunning et al. BIOLOGY OF REPRODUCTION
- Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner
- (2010) Adem Kalender et al. Cell Metabolism
- Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells
- (2010) Miguel Angel Esteban et al. Cell Stem Cell
- Autophagy and Metabolism
- (2010) J. D. Rabinowitz et al. SCIENCE
- Glutamine enhances heat shock protein 70 expression via increased hexosamine biosynthetic pathway activity
- (2009) Christine R. Hamiel et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- O-GlcNAc modifications regulate cell survival and epiboly during zebrafish development
- (2009) Danielle M Webster et al. BMC DEVELOPMENTAL BIOLOGY
- Cytokine regulation during the formation of the fetal–maternal interface: Focus on cell–cell adhesion and remodelling of the extra-cellular matrix
- (2009) Miranda McEwan et al. CYTOKINE & GROWTH FACTOR REVIEWS
- ExcessiveO-GlcNAcylation of proteins suppresses spontaneous cardiogenesis in ES cells
- (2009) Hoe-Suk Kim et al. FEBS LETTERS
- mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells
- (2009) J. Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dependence of Mouse Embryonic Stem Cells on Threonine Catabolism
- (2009) Jian Wang et al. SCIENCE
- Enrichment of undifferentiated mouse embryonic stem cells on a culture surface with a glucose-displaying dendrimer
- (2008) Shohreh Mashayekhan et al. BIOMATERIALS
- Up-regulation ofO-GlcNAc Transferase with Glucose Deprivation in HepG2 Cells Is Mediated by Decreased Hexosamine Pathway Flux
- (2008) Rodrick P. Taylor et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glucose Deprivation StimulatesO-GlcNAc Modification of Proteins through Up-regulation ofO-LinkedN-Acetylglucosaminyltransferase
- (2008) Rodrick P. Taylor et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of TORC1 by Rag GTPases in nutrient response
- (2008) Eunjung Kim et al. NATURE CELL BIOLOGY
- Albumin-Associated Lipids Regulate Human Embryonic Stem Cell Self-Renewal
- (2008) Francesc R. Garcia-Gonzalo et al. PLoS One
- The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1
- (2008) Y. Sancak et al. SCIENCE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started