The interplay of autophagy and oxidative stress in the pathogenesis and therapy of retinal degenerative diseases
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Title
The interplay of autophagy and oxidative stress in the pathogenesis and therapy of retinal degenerative diseases
Authors
Keywords
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Journal
Cell and Bioscience
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-01-04
DOI
10.1186/s13578-021-00736-9
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Note: Only part of the references are listed.- BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes
- (2021) Meysam Yazdankhah et al. Autophagy
- Is laser trabeculoplasty the new star in glaucoma treatment?
- (2021) Marc Töteberg-Harms et al. CURRENT OPINION IN OPHTHALMOLOGY
- p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response
- (2021) Shun Kageyama et al. Nature Communications
- Post-translational modification of Sox11 regulates RGC survival and axon regeneration
- (2021) Kun-Che Chang et al. eNeuro
- Chemokine CCL5 promotes robust optic nerve regeneration and mediates many of the effects of CNTF gene therapy
- (2021) Lili Xie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Early pars plana vitrectomy for proliferative diabetic retinopathy: update and review of current literature
- (2021) María H. Berrocal et al. CURRENT OPINION IN OPHTHALMOLOGY
- Primary cilia and the reciprocal activation of AKT and SMAD2/3 regulate stretch-induced autophagy in trabecular meshwork cells
- (2021) Myoung Sup Shim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The retinal pigment epithelium: Development, injury responses, and regenerative potential in mammalian and non-mammalian systems
- (2021) Stephanie M. George et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Age-related macular degeneration
- (2021) Monika Fleckenstein et al. Nature Reviews Disease Primers
- Novel Thiol Containing Hybrid Antioxidant-Nitric Oxide Donor Small Molecules for Treatment of Glaucoma
- (2021) Charles E. Amankwa et al. Antioxidants
- The E50K optineurin mutation impacts autophagy-mediated degradation of TDP-43 and leads to RGC apoptosis in vivo and in vitro
- (2021) Shiqi Zhang et al. Cell Death Discovery
- Scaffolds Facilitate Epiretinal Transplantation of hiPSC-Derived Retinal Neurons in Nonhuman Primates
- (2021) Ziming Luo et al. Acta Biomaterialia
- Comparative efficacy and safety of preserved versus preservative‐free beta‐blockers in patients with glaucoma or ocular hypertension: a systematic review
- (2021) Anne Guldhammer Skov et al. ACTA OPHTHALMOLOGICA
- Anterior segment imaging in minimally invasive glaucoma surgery – A systematic review
- (2021) John Tsia‐Chuen Kan et al. ACTA OPHTHALMOLOGICA
- Dexamethasone Downregulates Autophagy through Accelerated Turn-Over of the Ulk-1 Complex in a Trabecular Meshwork Cells Strain: Insights on Steroid-Induced Glaucoma Pathogenesis
- (2021) Diego Sbardella et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Potential of Telomerase in Age-Related Macular Degeneration—Involvement of Senescence, DNA Damage Response and Autophagy and a Key Role of PGC-1α
- (2021) Janusz Blasiak et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cyclodextrin-based formulation of carbonic anhydrase inhibitors for ocular delivery – A review
- (2021) Phatsawee Jansook et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Prostanoid receptor agonists for glaucoma treatment
- (2021) Makoto Aihara JAPANESE JOURNAL OF OPHTHALMOLOGY
- NF1 mutation drives neuronal activity-dependent initiation of optic glioma
- (2021) Yuan Pan et al. NATURE
- Injury-induced Autophagy Delays Axonal Regeneration after Optic Nerve Damage in Adult Zebrafish
- (2021) An Beckers et al. NEUROSCIENCE
- Antitumor effects of chloroquine/hydroxychloroquine mediated by inhibition of the NF-κB signaling pathway through abrogation of autophagic p47 degradation in adult T-cell leukemia/lymphoma cells
- (2021) Yanuar Rahmat Fauzi et al. PLoS One
- Molecular Features of Classic Retinal Drugs, Retinal Therapeutic Targets and Emerging Treatments
- (2021) Alessandro Arrigo et al. Pharmaceutics
- Anti-VEGF and Other Novel Therapies for Neovascular Age-Related Macular Degeneration: An Update
- (2021) Mariacristina Parravano et al. BIODRUGS
- The neurosteroid allopregnanolone protects retinal neurons by effects on autophagy and GABRs/GABAA receptors in rat glaucoma models
- (2020) Makoto Ishikawa et al. Autophagy
- Introduction to the multi-author review on macular degeneration
- (2020) Anu Kauppinen CELLULAR AND MOLECULAR LIFE SCIENCES
- Axonal protection by a small molecule SIRT1 activator, SRT2104, with alteration of autophagy in TNF-induced optic nerve degeneration
- (2020) Yasushi Kitaoka et al. JAPANESE JOURNAL OF OPHTHALMOLOGY
- PINK1 and Parkin mitochondrial quality control: a source of regional vulnerability in Parkinson’s disease
- (2020) Preston Ge et al. Molecular Neurodegeneration
- mTORC1 and mTORC2 expression in inner retinal neurons and glial cells
- (2020) Mandy K. Losiewicz et al. EXPERIMENTAL EYE RESEARCH
- Exosomal cargos modulate autophagy in recipient cells via different signaling pathways
- (2020) Mehdi Hassanpour et al. Cell and Bioscience
- Age related retinal Ganglion cell susceptibility in context of autophagy deficiency
- (2020) Katharina Bell et al. Cell Death Discovery
- Microautophagy – distinct molecular mechanisms handle cargoes of many sizes
- (2020) Sebastian Schuck JOURNAL OF CELL SCIENCE
- Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion
- (2020) Kazuaki Matoba et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Reconstitution of autophagosome nucleation defines Atg9 vesicles as seeds for membrane formation
- (2020) Justyna Sawa-Makarska et al. SCIENCE
- Rac1 conditional deletion attenuates retinal ganglion cell apoptosis by accelerating autophagic flux in a mouse model of chronic ocular hypertension
- (2020) Meng-Lu Zhang et al. Cell Death & Disease
- Axon Regeneration in the Mammalian Optic Nerve
- (2020) Philip R. Williams et al. Annual Review of Vision Science
- Quantitative Fundus Autofluorescence in Systemic Chloroquine/Hydroxychloroquine Therapy
- (2020) Clara Reichel et al. Translational Vision Science & Technology
- History, presence, and future of mitomycin C in glaucoma filtration surgery
- (2020) Jarno E.J. Wolters et al. CURRENT OPINION IN OPHTHALMOLOGY
- Inhibition of GCK-IV kinases dissociates cell death and axon regeneration in CNS neurons
- (2020) Amit K. Patel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Development of Aldose Reductase Inhibitors for the Treatment of Inflammatory Disorders and Cancer: Current Drug Design Strategies and Future Directions
- (2020) Himangshu Sonowal et al. CURRENT MEDICINAL CHEMISTRY
- Regulatory effects of noncoding RNAs on the interplay of oxidative stress and autophagy in cancer malignancy and therapy
- (2020) Pei-Feng Liu et al. SEMINARS IN CANCER BIOLOGY
- ERBB2-modulated ATG4B and autophagic cell death in human ARPE19 during oxidative stress
- (2019) Shwu-Jiuan Sheu et al. PLoS One
- Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium-Role in Dead Cell Clearance and Inflammation
- (2019) Mária Szatmári-Tóth et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Oxidative Stress: A Key Modulator in Neurodegenerative Diseases
- (2019) Anju Singh et al. MOLECULES
- Opposing Effects of Growth and Differentiation Factors in Cell-Fate Specification
- (2019) Kun-Che Chang et al. CURRENT BIOLOGY
- Cholinergic nervous system and glaucoma: From basic science to clinical applications
- (2019) Muneeb A. Faiq et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap1
- (2019) Takafumi Suzuki et al. Cell Reports
- Mitochondrial oxidative stress in the retinal pigment epithelium (RPE) led to metabolic dysfunction in both the RPE and retinal photoreceptors
- (2019) Emily E. Brown et al. Redox Biology
- Adrenergic agonists and antagonists as antiglaucoma agents: a literature and patent review (2013–2019)
- (2019) Alessio Nocentini et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Activation of autophagy in the retina after optic nerve crush injury in rats
- (2019) Li-Hua Kang International Journal of Ophthalmology
- Lysosome-associated membrane protein-2 deficiency increases the risk of reactive oxygen species-induced ferroptosis in retinal pigment epithelial cells
- (2019) Jong-Jer Lee et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Rho-kinase ROCK inhibitors reduce oligomeric tau protein
- (2019) Tadanori Hamano et al. NEUROBIOLOGY OF AGING
- Neferine induces autophagy-dependent cell death in apoptosis-resistant cancers via ryanodine receptor and Ca2+-dependent mechanism
- (2019) Betty Yuen Kwan Law et al. Scientific Reports
- Three Distinct Types of Microautophagy Based on Membrane Dynamics and Molecular Machineries
- (2018) Masahide Oku et al. BIOESSAYS
- Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease
- (2018) Tatsuya Yamada et al. Cell Metabolism
- Oxidative Stress Induces Neuronal Apoptosis Through Suppressing Transcription Factor EB Phosphorylation at Ser467
- (2018) Qian Su et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Reactive Oxygen Species in Metabolic and Inflammatory Signaling
- (2018) Steven J. Forrester et al. CIRCULATION RESEARCH
- mTOR signaling in stem and progenitor cells
- (2018) Delong Meng et al. DEVELOPMENT
- Increasing mtDNA levels as therapy for mitochondrial optic neuropathies
- (2018) Eduardo Ruiz-Pesini et al. DRUG DISCOVERY TODAY
- The coming of age of chaperone-mediated autophagy
- (2018) Susmita Kaushik et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Autophagy-mediated neuroprotection induced by octreotide in an ex vivo model of early diabetic retinopathy
- (2018) Rosario Amato et al. PHARMACOLOGICAL RESEARCH
- Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases
- (2018) Maria Angela Incalza et al. VASCULAR PHARMACOLOGY
- Cellular death, reactive oxygen species (ROS) and diabetic complications
- (2018) Caroline Maria Oliveira Volpe et al. Cell Death & Disease
- Retinal Ganglion Cell replacement: current status and challenges ahead
- (2018) Adam M. Miltner et al. DEVELOPMENTAL DYNAMICS
- Autophagy-dependent cell death – where, how and why a cell eats itself to death
- (2018) Shani Bialik et al. JOURNAL OF CELL SCIENCE
- Rapamycin and fasting sustain autophagy response activated by ischemia/reperfusion injury and promote retinal ganglion cell survival
- (2018) Rossella Russo et al. Cell Death & Disease
- Three-Dimensional Retinal Organoids Facilitate the Investigation of Retinal Ganglion Cell Development, Organization and Neurite Outgrowth from Human Pluripotent Stem Cells
- (2018) Clarisse M. Fligor et al. Scientific Reports
- The mammalian ULK1 complex and autophagy initiation
- (2017) Maria Zachari et al. Essays in Biochemistry
- Monitoring and Measuring Autophagy
- (2017) Saori R. Yoshii et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Stress-sensing mechanisms and the physiological roles of the Keap1–Nrf2 system during cellular stress
- (2017) Takafumi Suzuki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Reactive oxygen species trigger Parkin/PINK1 pathway–dependent mitophagy by inducing mitochondrial recruitment of Parkin
- (2017) Bin Xiao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Superoxide drives progression of Parkin/PINK1-dependent mitophagy following translocation of Parkin to mitochondria
- (2017) Bin Xiao et al. Cell Death & Disease
- Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration
- (2017) Nady Golestaneh et al. Cell Death & Disease
- Reversible Keap1 inhibitors are preferential pharmacological tools to modulate cellular mitophagy
- (2017) Nikolaos D. Georgakopoulos et al. Scientific Reports
- Enhanced Stem Cell Differentiation and Immunopurification of Genome Engineered Human Retinal Ganglion Cells
- (2017) Valentin M. Sluch et al. Stem Cells Translational Medicine
- Macular ganglion cell–inner plexiform layer thickness for detection of early retinal toxicity of hydroxychloroquine
- (2017) Emrah Kan et al. INTERNATIONAL OPHTHALMOLOGY
- Oxidative stress-mediated NFκB phosphorylation upregulates p62/SQSTM1 and promotes retinal pigmented epithelial cell survival through increased autophagy
- (2017) Chunjuan Song et al. PLoS One
- Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes
- (2016) Marta Pajares et al. Autophagy
- Autophagy regulates death of retinal pigment epithelium cells in age-related macular degeneration
- (2016) Kai Kaarniranta et al. CELL BIOLOGY AND TOXICOLOGY
- Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation
- (2016) Scot R. Kimball et al. CELLULAR SIGNALLING
- The Effect of Everolimus on Scar Formation in Glaucoma Filtering Surgery in a Rabbit Model
- (2016) Ruken Cinik et al. CURRENT EYE RESEARCH
- Autophagy in Diabetic Retinopathy
- (2016) Michelino Di Rosa et al. Current Neuropharmacology
- Optineurin: The autophagy connection
- (2016) Hongyu Ying et al. EXPERIMENTAL EYE RESEARCH
- Role of chaperone-mediated autophagy in metabolism
- (2016) Inmaculada Tasset et al. FEBS Journal
- Abrogation of Nrf2 impairs antioxidant signaling and promotes atrial hypertrophy in response to high-intensity exercise stress
- (2016) Radhakrishnan Rajesh Kumar et al. Journal of Translational Medicine
- Sestrin2 induced by hypoxia inducible factor1 alpha protects the blood-brain barrier via inhibiting VEGF after severe hypoxic-ischemic injury in neonatal rats
- (2016) Xudan Shi et al. NEUROBIOLOGY OF DISEASE
- Involvement of Autophagic Pathway in the Progression of Retinal Degeneration in a Mouse Model of Diabetes
- (2016) Ilaria Piano et al. Frontiers in Cellular Neuroscience
- Clearance of autophagy-associated dying retinal pigment epithelial cells – a possible source for inflammation in age-related macular degeneration
- (2016) M Szatmári-Tóth et al. Cell Death & Disease
- Highly Multiplexed Quantitative Mass Spectrometry Analysis of Ubiquitylomes
- (2016) Christopher M. Rose et al. Cell Systems
- Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy
- (2016) J. Julie Wu et al. Aging-US
- Impairing autophagy in retinal pigment epithelium leads to inflammasome activation and enhanced macrophage-mediated angiogenesis
- (2016) Jian Liu et al. Scientific Reports
- Autophagic dysregulation in glaucomatous trabecular meshwork cells
- (2015) Kristine Porter et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Mitochondrial ROS Signaling in Organismal Homeostasis
- (2015) Gerald S. Shadel et al. CELL
- Aldose reductase inhibition alleviates hyperglycemic effects on human retinal pigment epithelial cells
- (2015) Kun-Che Chang et al. CHEMICO-BIOLOGICAL INTERACTIONS
- PINK1/Parkin-mediated mitophagy in mammalian cells
- (2015) Akinori Eiyama et al. CURRENT OPINION IN CELL BIOLOGY
- The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy
- (2015) Jin-Mi Heo et al. MOLECULAR CELL
- ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes
- (2015) Jiajie Diao et al. NATURE
- ATM functions at the peroxisome to induce pexophagy in response to ROS
- (2015) Jiangwei Zhang et al. NATURE CELL BIOLOGY
- Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway
- (2015) R. A. Saxton et al. SCIENCE
- Protective effect of autophagy on human retinal pigment epithelial cells against lipofuscin fluorophore A2E: implications for age-related macular degeneration
- (2015) J Zhang et al. Cell Death & Disease
- Janus-faced Sestrin2 controls ROS and mTOR signalling through two separate functional domains
- (2015) Hanseong Kim et al. Nature Communications
- Regulation of autophagic cell death by glycogen synthase kinase-3β in adult hippocampal neural stem cells following insulin withdrawal
- (2015) Shinwon Ha et al. Molecular Brain
- Proteotoxic Stress Induces Phosphorylation of p62/SQSTM1 by ULK1 to Regulate Selective Autophagic Clearance of Protein Aggregates
- (2015) Junghyun Lim et al. PLoS Genetics
- Association of Geroprotective Effects of Metformin and Risk of Open-Angle Glaucoma in Persons With Diabetes Mellitus
- (2015) Hsien-Chang Lin et al. JAMA Ophthalmology
- NRF2 Regulates PINK1 Expression under Oxidative Stress Conditions
- (2015) Hitoshi Murata et al. PLoS One
- Lithium and Autophagy
- (2014) Yumiko Motoi et al. ACS Chemical Neuroscience
- Dynamics and function of PtdIns(3)Pin autophagy
- (2014) Keisuke Obara et al. Autophagy
- Oxidative stress induces autophagy in response to multiple noxious stimuli in retinal ganglion cells
- (2014) Wen-jian Lin et al. Autophagy
- Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD
- (2014) Sayak K Mitter et al. Autophagy
- Oxidative stress and autophagy: the clash between damage and metabolic needs
- (2014) G Filomeni et al. CELL DEATH AND DIFFERENTIATION
- Regulation of Autophagy by High Glucose in Human Retinal Pigment Epithelium
- (2014) Jin Yao et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- The HOPS complex mediates autophagosome–lysosome fusion through interaction with syntaxin 17
- (2014) Peidu Jiang et al. MOLECULAR BIOLOGY OF THE CELL
- Hexokinase-II Positively Regulates Glucose Starvation-Induced Autophagy through TORC1 Inhibition
- (2014) David J. Roberts et al. MOLECULAR CELL
- Early Steps in Autophagy Depend on Direct Phosphorylation of Atg9 by the Atg1 Kinase
- (2014) Daniel Papinski et al. MOLECULAR CELL
- Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy
- (2014) Vladimir Rogov et al. MOLECULAR CELL
- Temsirolimus Inhibits Proliferation and Migration in Retinal Pigment Epithelial and Endothelial Cells via mTOR Inhibition and Decreases VEGF and PDGF Expression
- (2014) Raffael Liegl et al. PLoS One
- Differential Angiogenic Properties of Lithium Chloride In Vitro and In Vivo
- (2014) Ludwig F. Zeilbeck et al. PLoS One
- Rapamycin Is Neuroprotective in a Rat Chronic Hypertensive Glaucoma Model
- (2014) Wenru Su et al. PLoS One
- Inhibition of cathepsin S induces autophagy and apoptosis in human glioblastoma cell lines through ROS-mediated PI3K/AKT/mTOR/p70S6K and JNK signaling pathways
- (2014) Li Zhang et al. TOXICOLOGY LETTERS
- Everolimus-Induced Posterior Reversible Encephalopathy Syndrome and Bilateral Optic Neuropathy After Kidney Transplantation
- (2014) Sara Touhami et al. TRANSPLANTATION
- Glutathione and mitochondria
- (2014) Vicent Ribas et al. Frontiers in Pharmacology
- Defective mitophagy driven by dysregulation of rheb and KIF5B contributes to mitochondrial reactive oxygen species (ROS)-induced nod-like receptor 3 (NLRP3) dependent proinflammatory response and aggravates lipotoxicity
- (2014) Sijun Yang et al. Redox Biology
- Balance between autophagic pathways preserves retinal homeostasis
- (2013) Natalia Rodríguez-Muela et al. AGING CELL
- Differential Regulation of Distinct Vps34 Complexes by AMPK in Nutrient Stress and Autophagy
- (2013) Joungmok Kim et al. CELL
- Historical landmarks of autophagy research
- (2013) Yoshinori Ohsumi CELL RESEARCH
- Rapamycin drives selection against a pathogenic heteroplasmic mitochondrial DNA mutation
- (2013) Ying Dai et al. HUMAN MOLECULAR GENETICS
- Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy
- (2013) Yoshinobu Ichimura et al. MOLECULAR CELL
- Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
- (2013) Shireen A. Sarraf et al. NATURE
- A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS
- (2013) Jiangwei Zhang et al. NATURE CELL BIOLOGY
- The autophagosome: origins unknown, biogenesis complex
- (2013) Christopher A. Lamb et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Structural basis of ATG3 recognition by the autophagic ubiquitin-like protein ATG12
- (2013) Z. Metlagel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1
- (2013) D. N. Tripathi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ROS-induced mitochondrial depolarization initiates PARK2/PARKIN-dependent mitochondrial degradation by autophagy
- (2012) Yuqing Wang et al. Autophagy
- Axonal damage, autophagy and neuronal survival
- (2012) Natalia Rodríguez-Muela et al. Autophagy
- Architecture of the Atg17 Complex as a Scaffold for Autophagosome Biogenesis
- (2012) Michael J. Ragusa et al. CELL
- Upregulation of sestrin 2 expression via JNK pathway activation contributes to autophagy induction in cancer cells
- (2012) Xiao-Yue Zhang et al. CELLULAR SIGNALLING
- In search of new targets for retinal neuroprotection: is there a role for autophagy?
- (2012) Rossella Russo et al. CURRENT OPINION IN PHARMACOLOGY
- Mechanisms of modified LDL-induced pericyte loss and retinal injury in diabetic retinopathy
- (2012) D. Fu et al. DIABETOLOGIA
- Nrf2-ARE pathway regulates induction of Sestrin-2 expression
- (2012) Bo Yeon Shin et al. FREE RADICAL BIOLOGY AND MEDICINE
- Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy
- (2012) Chinatsu Otomo et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mechanisms of Age-Related Macular Degeneration
- (2012) Jayakrishna Ambati et al. NEURON
- Chaperone-mediated autophagy: a unique way to enter the lysosome world
- (2012) Susmita Kaushik et al. TRENDS IN CELL BIOLOGY
- The Role of Atg Proteins in Autophagosome Formation
- (2011) Noboru Mizushima et al. Annual Review of Cell and Developmental Biology
- Superoxide Dismutases: Role in Redox Signaling, Vascular Function, and Diseases
- (2011) Tohru Fukai et al. ANTIOXIDANTS & REDOX SIGNALING
- Selective autophagy mediated by autophagic adapter proteins
- (2011) Terje Johansen et al. Autophagy
- Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
- (2011) Jisun Lee et al. BIOCHEMICAL JOURNAL
- Role of peroxisomes in ROS/RNS-metabolism: Implications for human disease
- (2011) Marc Fransen et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- ATM activation in the presence of oxidative stress
- (2011) Zhi Guo et al. CELL CYCLE
- Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice
- (2011) N Rodríguez-Muela et al. CELL DEATH AND DIFFERENTIATION
- Microautophagy of Cytosolic Proteins by Late Endosomes
- (2011) Ranjit Sahu et al. DEVELOPMENTAL CELL
- Mitophagy Plays an Essential Role in Reducing Mitochondrial Production of Reactive Oxygen Species and Mutation of Mitochondrial DNA by Maintaining Mitochondrial Quantity and Quality in Yeast
- (2011) Yusuke Kurihara et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Multifocal malignant optic glioma of adulthood presenting as acute anterior optic neuropathy
- (2011) Selma Matloob et al. JOURNAL OF CLINICAL NEUROSCIENCE
- Metformin and cancer: new applications for an old drug
- (2011) Taxiarchis V. Kourelis et al. MEDICAL ONCOLOGY
- Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks
- (2011) S. Alers et al. MOLECULAR AND CELLULAR BIOLOGY
- TFEB Links Autophagy to Lysosomal Biogenesis
- (2011) C. Settembre et al. SCIENCE
- The ATM protein kinase and cellular redox signaling: beyond the DNA damage response
- (2011) Scott Ditch et al. TRENDS IN BIOCHEMICAL SCIENCES
- Potential Therapeutic Roles for Inhibition of the PI3K/Akt/mTOR Pathway in the Pathophysiology of Diabetic Retinopathy
- (2011) Jorge L. Jacot et al. Journal of Ophthalmology
- Under the ROS: Thiol network is the principal suspect for autophagy commitment
- (2010) Giuseppe Filomeni et al. Autophagy
- The role of the Atg1/ULK1 complex in autophagy regulation
- (2010) Noboru Mizushima CURRENT OPINION IN CELL BIOLOGY
- LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis
- (2010) Hilla Weidberg et al. EMBO JOURNAL
- p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription
- (2010) Ashish Jain et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- Mechanisms of mitophagy
- (2010) Richard J. Youle et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mechanisms of acute axonal degeneration in the optic nerve in vivo
- (2010) J. Knoferle et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS
- (2010) A. Alexander et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sestrin as a Feedback Inhibitor of TOR That Prevents Age-Related Pathologies
- (2010) J. H. Lee et al. SCIENCE
- ATM Activation by Oxidative Stress
- (2010) Z. Guo et al. SCIENCE
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- (2010) Samantha J. Orenstein et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Reactive oxygen species and peroxisomes: Struggling for balance
- (2009) Nina A. Bonekamp et al. BIOFACTORS
- Superoxide is the major reactive oxygen species regulating autophagy
- (2009) Y Chen et al. CELL DEATH AND DIFFERENTIATION
- Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity
- (2009) Juxiang Cao et al. EMBO JOURNAL
- Nrf2:INrf2 (Keap1) signaling in oxidative stress
- (2009) James W. Kaspar et al. FREE RADICAL BIOLOGY AND MEDICINE
- Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains
- (2009) G. Bellot et al. MOLECULAR AND CELLULAR BIOLOGY
- Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex
- (2009) Yun Zhong et al. NATURE CELL BIOLOGY
- Autophagy and Exosomes in the Aged Retinal Pigment Epithelium: Possible Relevance to Drusen Formation and Age-Related Macular Degeneration
- (2009) Ai Ling Wang et al. PLoS One
- Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling
- (2009) Michal Caspi Tal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- KLF Family Members Regulate Intrinsic Axon Regeneration Ability
- (2009) D. L. Moore et al. SCIENCE
- How mitochondria produce reactive oxygen species
- (2008) Michael P. Murphy BIOCHEMICAL JOURNAL
- Activation of autophagy in retinal ganglion cells
- (2008) Seok Hwan Kim et al. JOURNAL OF NEUROSCIENCE RESEARCH
- The Chaperone-Mediated Autophagy Receptor Organizes in Dynamic Protein Complexes at the Lysosomal Membrane
- (2008) U. Bandyopadhyay et al. MOLECULAR AND CELLULAR BIOLOGY
- Organization of the Pre-autophagosomal Structure Responsible for Autophagosome Formation
- (2008) Tomoko Kawamata et al. MOLECULAR BIOLOGY OF THE CELL
- Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking
- (2008) Chengyu Liang et al. NATURE CELL BIOLOGY
- Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway
- (2008) K. K. Park et al. SCIENCE
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