PINK1 and Parkin mitochondrial quality control: a source of regional vulnerability in Parkinson’s disease
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
PINK1 and Parkin mitochondrial quality control: a source of regional vulnerability in Parkinson’s disease
Authors
Keywords
-
Journal
Molecular Neurodegeneration
Volume 15, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-03-14
DOI
10.1186/s13024-020-00367-7
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Peripheral-Central Neuroimmune Crosstalk in Parkinson's Disease: What Do Patients and Animal Models Tell Us?
- (2019) Marie Therese Fuzzati-Armentero et al. Frontiers in Neurology
- Assessment of mitophagy in mt-Keima Drosophila revealed an essential role of the PINK1-Parkin pathway in mitophagy induction in vivo
- (2019) Young Yeon Kim et al. FASEB JOURNAL
- Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson’s disease
- (2019) Saurav Brahmachari et al. BRAIN
- Intestinal infection triggers Parkinson’s disease-like symptoms in Pink1−/− mice
- (2019) Diana Matheoud et al. NATURE
- Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease
- (2019) Sangjune Kim et al. NEURON
- Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation
- (2019) Panagiota Kolitsida et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The PINK1 kinase-driven ubiquitin ligase Parkin promotes mitochondrial protein import through the presequence pathway in living cells
- (2019) M. Jacoupy et al. Scientific Reports
- Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease
- (2018) Tatsuya Yamada et al. Cell Metabolism
- Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand
- (2018) Thomas G. McWilliams et al. Cell Metabolism
- Mitochondrial Dysfunction in Parkinson’s Disease: New Mechanistic Insights and Therapeutic Perspectives
- (2018) Jin-Sung Park et al. Current Neurology and Neuroscience Reports
- PINK1 autophosphorylation is required for ubiquitin recognition
- (2018) Shafqat Rasool et al. EMBO REPORTS
- Parkin deficiency modulates NLRP3 inflammasome activation by attenuating an A20-dependent negative feedback loop
- (2018) François Mouton-Liger et al. GLIA
- Comparative analysis of Parkinson's disease–associated genes in mice reveals altered survival and bioenergetics of Parkin-deficient dopamine neurons
- (2018) Nicolas Giguère et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Basal mitophagy is widespread inDrosophilabut minimally affected by loss of Pink1 or parkin
- (2018) Juliette J. Lee et al. JOURNAL OF CELL BIOLOGY
- Cell-Specific Deletion of PGC-1α from Medium Spiny Neurons Causes Transcriptional Alterations and Age-Related Motor Impairment
- (2018) Laura J. McMeekin et al. JOURNAL OF NEUROSCIENCE
- Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics
- (2018) Alban Ordureau et al. MOLECULAR CELL
- Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve
- (2018) Norihito Uemura et al. Molecular Neurodegeneration
- The multifaceted contributions of mitochondria to cellular metabolism
- (2018) Jessica B. Spinelli et al. NATURE CELL BIOLOGY
- Building and decoding ubiquitin chains for mitophagy
- (2018) J. Wade Harper et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Phosphorylation of Parkin at serine 131 by p38 MAPK promotes mitochondrial dysfunction and neuronal death in mutant A53T α-synuclein model of Parkinson’s disease
- (2018) Jialong Chen et al. Cell Death & Disease
- Lack of PINK1 alters glia innate immune responses and enhances inflammation-induced, nitric oxide-mediated neuron death
- (2018) Liuke Sun et al. Scientific Reports
- Endosomal Rab cycles regulate Parkin-mediated mitophagy
- (2018) Koji Yamano et al. eLife
- Deficiency of parkin and PINK1 impairs age-dependent mitophagy in Drosophila
- (2018) Tom Cornelissen et al. eLife
- On Cell Loss and Selective Vulnerability of Neuronal Populations in Parkinson's Disease
- (2018) Nicolas Giguère et al. Frontiers in Neurology
- Parkin and PINK1 mitigate STING-induced inflammation
- (2018) Danielle A. Sliter et al. NATURE
- Mechanisms of mitophagy in cellular homeostasis, physiology and pathology
- (2018) Konstantinos Palikaras et al. NATURE CELL BIOLOGY
- No Parkin Zone: Mitophagy without Parkin
- (2018) Elodie Villa et al. TRENDS IN CELL BIOLOGY
- Mitochondria-Derived Vesicles Deliver Antimicrobial Reactive Oxygen Species to Control Phagosome-Localized Staphylococcus aureus
- (2018) Basel H. Abuaita et al. Cell Host & Microbe
- Parkin targets NOD2 to regulate astrocyte endoplasmic reticulum stress and inflammation
- (2018) Komudi Singh et al. GLIA
- LRRK2 G2019S-induced mitochondrial DNA damage is LRRK2 kinase dependent and inhibition restores mtDNA integrity in Parkinson’s disease
- (2017) Evan H Howlett et al. HUMAN MOLECULAR GENETICS
- Mitochondrial fission facilitates the selective mitophagy of protein aggregates
- (2017) Jonathon L. Burman et al. JOURNAL OF CELL BIOLOGY
- Prying into the Prion Hypothesis for Parkinson's Disease
- (2017) Patrik Brundin et al. JOURNAL OF NEUROSCIENCE
- Mitochondrial Calcium Dysregulation Contributes to Dendrite Degeneration Mediated by PD/LBD-Associated LRRK2 Mutants
- (2017) Manish Verma et al. JOURNAL OF NEUROSCIENCE
- Quantitative proteomic analysis of Parkin substrates in Drosophila neurons
- (2017) Aitor Martinez et al. Molecular Neurodegeneration
- Mitochondrial DNA and primary mitochondrial dysfunction in Parkinson's disease
- (2017) Maria Pia Giannoccaro et al. MOVEMENT DISORDERS
- Neuropathology of genetic synucleinopathies with parkinsonism: Review of the literature
- (2017) Susanne A. Schneider et al. MOVEMENT DISORDERS
- Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy
- (2017) J.A. Obeso et al. MOVEMENT DISORDERS
- T cells from patients with Parkinson’s disease recognize α-synuclein peptides
- (2017) David Sulzer et al. NATURE
- Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes
- (2017) Ayumu Sugiura et al. NATURE
- Selective neuronal vulnerability in Parkinson disease
- (2017) D. James Surmeier et al. NATURE REVIEWS NEUROSCIENCE
- Mitostasis in Neurons: Maintaining Mitochondria in an Extended Cellular Architecture
- (2017) Thomas Misgeld et al. NEURON
- Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation
- (2017) Matthew Y. Tang et al. Nature Communications
- PINK1 Primes Parkin-Mediated Ubiquitination of PARIS in Dopaminergic Neuronal Survival
- (2017) Yunjong Lee et al. Cell Reports
- Mitochondrial DNA Depletion in Respiratory Chain-Deficient Parkinson Disease Neurons
- (2016) Anne Grünewald et al. ANNALS OF NEUROLOGY
- Dynamic Axonal Translation in Developing and Mature Visual Circuits
- (2016) Toshiaki Shigeoka et al. CELL
- Parkinson’s Disease-Related Proteins PINK1 and Parkin Repress Mitochondrial Antigen Presentation
- (2016) Diana Matheoud et al. CELL
- Mitochondrial quality control by the Pink1/Parkin system
- (2016) Cornelia Rüb et al. CELL AND TISSUE RESEARCH
- Dual Function of Phosphoubiquitin in E3 Activation of Parkin
- (2016) Erik Walinda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system
- (2016) Gian-Luca McLelland et al. JOURNAL OF CELL BIOLOGY
- PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy
- (2016) Kenneth R. Pryde et al. JOURNAL OF CELL BIOLOGY
- mito-QC illuminates mitophagy and mitochondrial architecture in vivo
- (2016) Thomas G. McWilliams et al. JOURNAL OF CELL BIOLOGY
- Metabolic regulation of mitochondrial dynamics
- (2016) Prashant Mishra et al. JOURNAL OF CELL BIOLOGY
- Activation of tyrosine kinase c-Abl contributes to α-synuclein–induced neurodegeneration
- (2016) Saurav Brahmachari et al. JOURNAL OF CLINICAL INVESTIGATION
- The mitochondrial kinase PINK1: functions beyond mitophagy
- (2016) Aaron Voigt et al. JOURNAL OF NEUROCHEMISTRY
- Molecular changes in the postmortem parkinsonian brain
- (2016) Damien Toulorge et al. JOURNAL OF NEUROCHEMISTRY
- Mitochondrial dysfunction in Parkinson's disease
- (2016) Anindita Bose et al. JOURNAL OF NEUROCHEMISTRY
- Compartmentalized Regulation of Parkin-Mediated Mitochondrial Quality Control in the Drosophila Nervous System In Vivo
- (2016) H. Sung et al. JOURNAL OF NEUROSCIENCE
- Formation of mitochondrial-derived vesicles is an active and physiologically relevant mitochondrial quality control process in the cardiac system
- (2016) Virgilio J. J. Cadete et al. JOURNAL OF PHYSIOLOGY-LONDON
- A heterogeneous population of nuclear-encoded mitochondrial mRNAs is present in the axons of primary sympathetic neurons
- (2016) Armaz Aschrafi et al. MITOCHONDRION
- Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation
- (2016) Kuan-Chuan Pao et al. Nature Chemical Biology
- Somatic mtDNA variation is an important component of Parkinson's disease
- (2016) Jonathan Coxhead et al. NEUROBIOLOGY OF AGING
- Detrimental effects of oxidative losses in parkin activity in a model of sporadic Parkinson's disease are attenuated by restoration of PGC1alpha
- (2016) Almas Siddiqui et al. NEUROBIOLOGY OF DISEASE
- Structure of phosphorylated UBL domain and insights into PINK1-orchestrated parkin activation
- (2016) Jacob D. Aguirre et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathological -synuclein transmission initiated by binding lymphocyte-activation gene 3
- (2016) X. Mao et al. SCIENCE
- A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1
- (2016) Y. Wang et al. SCIENCE
- Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease
- (2016) Christian Dölle et al. Nature Communications
- Highly Multiplexed Quantitative Mass Spectrometry Analysis of Ubiquitylomes
- (2016) Christopher M. Rose et al. Cell Systems
- Parkin maintains mitochondrial levels of the protective Parkinson’s disease-related enzyme 17-β hydroxysteroid dehydrogenase type 10
- (2015) G Bertolin et al. CELL DEATH AND DIFFERENTIATION
- PINK1 and Parkin Control Localized Translation of Respiratory Chain Component mRNAs on Mitochondria Outer Membrane
- (2015) Stephan Gehrke et al. Cell Metabolism
- Elevated Mitochondrial Bioenergetics and Axonal Arborization Size Are Key Contributors to the Vulnerability of Dopamine Neurons
- (2015) Consiglia Pacelli et al. CURRENT BIOLOGY
- Phosphorylated ubiquitin chain is the genuine Parkin receptor
- (2015) Kei Okatsu et al. JOURNAL OF CELL BIOLOGY
- Mitochondrial Quality Control via the PGC1 -TFEB Signaling Pathway Is Compromised by Parkin Q311X Mutation But Independently Restored by Rapamycin
- (2015) A. Siddiqui et al. JOURNAL OF NEUROSCIENCE
- The Organization of Mitochondrial Quality Control and Life Cycle in the Nervous System In Vivo in the Absence of PINK1
- (2015) S. Devireddy et al. JOURNAL OF NEUROSCIENCE
- Measuring In Vivo Mitophagy
- (2015) Nuo Sun et al. MOLECULAR CELL
- The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy
- (2015) Jin-Mi Heo et al. MOLECULAR CELL
- The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
- (2015) Michael Lazarou et al. NATURE
- USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria
- (2015) Christian N. Cunningham et al. NATURE CELL BIOLOGY
- Parkinson's disease–associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes
- (2015) Wenzhang Wang et al. NATURE MEDICINE
- Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress
- (2015) Alicia M. Pickrell et al. NEURON
- The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
- (2015) Alicia M. Pickrell et al. NEURON
- STEP61is a substrate of the E3 ligase parkin and is upregulated in Parkinson’s disease
- (2015) Pradeep K. Kurup et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy
- (2015) Alban Ordureau et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration
- (2015) Daniel A. Stevens et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Localized translation near the mitochondrial outer membrane: An update
- (2015) Chen Lesnik et al. RNA Biology
- VPS35 Deficiency or Mutation Causes Dopaminergic Neuronal Loss by Impairing Mitochondrial Fusion and Function
- (2015) Fu-Lei Tang et al. Cell Reports
- PGC-1α activity in nigral dopamine neurons determines vulnerability to α-synuclein
- (2015) Carine Ciron et al. Acta Neuropathologica Communications
- Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization
- (2014) Judith Eschbach et al. ANNALS OF NEUROLOGY
- Functional interplay between Parkin and Drp1 in mitochondrial fission and clearance
- (2014) Lori Buhlman et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Autophagosome Biogenesis in Primary Neurons Follows an Ordered and Spatially Regulated Pathway
- (2014) Sandra Maday et al. DEVELOPMENTAL CELL
- A new pathway for mitochondrial quality control: mitochondrial-derived vesicles
- (2014) A. Sugiura et al. EMBO JOURNAL
- c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease
- (2014) Anne-Laure Mahul-Mellier et al. HUMAN MOLECULAR GENETICS
- Parkinson's disease-associated human ATP13A2 (PARK9) deficiency causes zinc dyshomeostasis and mitochondrial dysfunction
- (2014) Jin-Sung Park et al. HUMAN MOLECULAR GENETICS
- Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin
- (2014) Ghazaleh Ashrafi et al. JOURNAL OF CELL BIOLOGY
- Impaired OMA1-dependent cleavage of OPA1 and reduced DRP1 fission activity combine to prevent mitophagy in cells that are dependent on oxidative phosphorylation
- (2014) Thomas D. B. MacVicar et al. JOURNAL OF CELL SCIENCE
- Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis
- (2014) Alban Ordureau et al. MOLECULAR CELL
- Ubiquitin is phosphorylated by PINK1 to activate parkin
- (2014) Fumika Koyano et al. NATURE
- Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation
- (2014) Yvette C. Wong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling
- (2014) C. C. Williams et al. SCIENCE
- Parkin and PINK1: much more than mitophagy
- (2014) Leslie A. Scarffe et al. TRENDS IN NEUROSCIENCES
- MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration
- (2014) Carolina Cebrián et al. Nature Communications
- Morphological and bioenergetic demands underlying the mitophagy in post-mitotic neurons: the pink–parkin pathway
- (2014) Giuseppina Amadoro et al. Frontiers in Aging Neuroscience
- Phosphorylation of Mitochondrial Polyubiquitin by PINK1 Promotes Parkin Mitochondrial Tethering
- (2014) Kahori Shiba-Fukushima et al. PLoS Genetics
- S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson’s disease
- (2013) Carmen R Sunico et al. Molecular Neurodegeneration
- TheVPS35gene and Parkinson's disease
- (2013) Hao Deng et al. MOVEMENT DISORDERS
- Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
- (2013) Shireen A. Sarraf et al. NATURE
- Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss
- (2013) Yunjong Lee et al. NATURE NEUROSCIENCE
- The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo
- (2013) E. S. Vincow et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation
- (2013) J.-F. Trempe et al. SCIENCE
- Mechanisms of Mitochondrial Fission and Fusion
- (2013) A. M. van der Bliek et al. Cold Spring Harbor Perspectives in Biology
- Involvement of mitochondrial dynamics in the segregation of mitochondrial matrix proteins during stationary phase mitophagy
- (2013) Hagai Abeliovich et al. Nature Communications
- Genetics of Parkinson's Disease
- (2013) C. Klein et al. Cold Spring Harbor Perspectives in Medicine
- Parkin Disease
- (2013) Karen M. Doherty et al. JAMA Neurology
- Parkin- and PINK1-Dependent Mitophagy in Neurons: Will the Real Pathway Please Stand Up?
- (2013) Karl Grenier et al. Frontiers in Neurology
- The genetics and neuropathology of Parkinson’s disease
- (2012) Henry Houlden et al. ACTA NEUROPATHOLOGICA
- Spatial Parkin Translocation and Degradation of Damaged Mitochondria via Mitophagy in Live Cortical Neurons
- (2012) Qian Cai et al. CURRENT BIOLOGY
- A Vesicular Transport Pathway Shuttles Cargo from Mitochondria to Lysosomes
- (2012) Vincent Soubannier et al. CURRENT BIOLOGY
- Sustained expression of PGC-1 in the rat nigrostriatal system selectively impairs dopaminergic function
- (2012) C. Ciron et al. HUMAN MOLECULAR GENETICS
- Mitochondrial division ensures the survival of postmitotic neurons by suppressing oxidative damage
- (2012) Yusuke Kageyama et al. JOURNAL OF CELL BIOLOGY
- Living on the edge with too many mouths to feed: Why dopamine neurons die
- (2012) J. Paul Bolam et al. MOVEMENT DISORDERS
- Decreased parkin solubility is associated with impairment of autophagy in the nigrostriatum of sporadic Parkinson’s disease
- (2012) I. Lonskaya et al. NEUROSCIENCE
- Pgc-1α Overexpression Downregulates Pitx3 and Increases Susceptibility to MPTP Toxicity Associated with Decreased Bdnf
- (2012) Joanne Clark et al. PLoS One
- Reconstitution of Mitochondria Derived Vesicle Formation Demonstrates Selective Enrichment of Oxidized Cargo
- (2012) Vincent Soubannier et al. PLoS One
- Pathological -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
- (2012) K. C. Luk et al. SCIENCE
- PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease
- (2011) Joo-Ho Shin et al. CELL
- Rotenone, Paraquat, and Parkinson’s Disease
- (2011) Caroline M. Tanner et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity
- (2011) David Ramonet et al. HUMAN MOLECULAR GENETICS
- The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons
- (2011) Wendou Yu et al. HUMAN MOLECULAR GENETICS
- Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1
- (2011) Liliane Glauser et al. JOURNAL OF NEUROCHEMISTRY
- Mitochondrial Parkin Recruitment Is Impaired in Neurons Derived from Mutant PINK1 Induced Pluripotent Stem Cells
- (2011) P. Seibler et al. JOURNAL OF NEUROSCIENCE
- Novel Regulation of Parkin Function through c-Abl-Mediated Tyrosine Phosphorylation: Implications for Parkinson's Disease
- (2011) S. Z. Imam et al. JOURNAL OF NEUROSCIENCE
- Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death
- (2011) Laura A. Volpicelli-Daley et al. NEURON
- Mutations in PINK1 and Parkin Impair Ubiquitination of Mitofusins in Human Fibroblasts
- (2011) Aleksandar Rakovic et al. PLoS One
- Vps35 Mediates Vesicle Transport between the Mitochondria and Peroxisomes
- (2010) Emélie Braschi et al. CURRENT BIOLOGY
- Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization
- (2010) Victor S. Van Laar et al. HUMAN MOLECULAR GENETICS
- Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
- (2010) Matthew E. Gegg et al. HUMAN MOLECULAR GENETICS
- Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
- (2010) Atsushi Tanaka et al. JOURNAL OF CELL BIOLOGY
- PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
- (2010) Noriyuki Matsuda et al. JOURNAL OF CELL BIOLOGY
- Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1
- (2010) Jaime N. Guzman et al. NATURE
- PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
- (2010) Sven Geisler et al. NATURE CELL BIOLOGY
- The Mitochondrial Fusion-Promoting Factor Mitofusin Is a Substrate of the PINK1/Parkin Pathway
- (2010) Angela C. Poole et al. PLoS One
- Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin
- (2010) E. Ziviani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function
- (2010) H. S. Ko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PGC-1 , A Potential Therapeutic Target for Early Intervention in Parkinson's Disease
- (2010) B. Zheng et al. Science Translational Medicine
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- (2010) Derek P. Narendra et al. PLOS BIOLOGY
- Importing Mitochondrial Proteins: Machineries and Mechanisms
- (2009) Agnieszka Chacinska et al. CELL
- Programmed cell death-2 isoform1 is ubiquitinated by parkin and increased in the substantia nigra of patients with autosomal recessive Parkinson's disease
- (2009) Jiro Fukae et al. FEBS LETTERS
- Human brain cortex: mitochondrial oxidative damage and adaptive response in Parkinson disease and in dementia with Lewy bodies
- (2009) Ana Navarro et al. FREE RADICAL BIOLOGY AND MEDICINE
- Single Nigrostriatal Dopaminergic Neurons Form Widely Spread and Highly Dense Axonal Arborizations in the Neostriatum
- (2009) W. Matsuda et al. JOURNAL OF NEUROSCIENCE
- PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
- (2009) C. Vives-Bauza et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The PINK1–Parkin pathway is involved in the regulation of mitochondrial remodeling process
- (2008) Jeehye Park et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- α-Synuclein Aggregates Interfere with Parkin Solubility and Distribution
- (2008) Kohichi Kawahara et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
- A Dopaminergic Axon Lattice in the Striatum and Its Relationship with Cortical and Thalamic Terminals
- (2008) J. Moss et al. JOURNAL OF NEUROSCIENCE
- Glial Dysfunction in Parkin Null Mice: Effects of Aging
- (2008) R. M. Solano et al. JOURNAL OF NEUROSCIENCE
- Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
- (2008) Jia-Yi Li et al. NATURE MEDICINE
- Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease
- (2008) Jeffrey H Kordower et al. NATURE MEDICINE
- Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery
- (2008) Y. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The PINK1/Parkin pathway regulates mitochondrial morphology
- (2008) A. C. Poole et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
- (2008) H. Deng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pesticide/Environmental Exposures and Parkinson's Disease in East Texas
- (2008) Amanpreet S. Dhillon et al. Journal of Agromedicine
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started