Rapamycin and fasting sustain autophagy response activated by ischemia/reperfusion injury and promote retinal ganglion cell survival

Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities

(2017) Fiona M. Menzies et al.   NEURON

Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation

(2016) Marisa Ferreira-Marques et al.   Aging-US

Mammalian Autophagy: How Does It Work?

(2016) Carla F. Bento et al.   Annual Review of Biochemistry

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Unraveling the roles of Atg4 proteases from autophagy modulation to targeted cancer therapy

(2016) Lan Zhang et al.   CANCER LETTERS

Autophagy core machinery: overcoming spatial barriers in neurons

(2016) Aileen R. Ariosa et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Autophagy in the eye: Development, degeneration, and aging

(2016) Patricia Boya et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Autophagy supports color vision

(2015) Zhenqing Zhou et al.   Autophagy

Autophagy and neurodegeneration

(2015) Rebecca A. Frake et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagic flux determination in vivo and ex vivo

(2015) Lorena Esteban-Martínez et al.   METHODS

Erratum: Corrigendum: AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation

(2015) Valentina Cianfanelli et al.   NATURE CELL BIOLOGY

Association of Geroprotective Effects of Metformin and Risk of Open-Angle Glaucoma in Persons With Diabetes Mellitus

(2015) Hsien-Chang Lin et al.   JAMA Ophthalmology

Expression of the autophagy substrate SQSTM1/p62 is restored during prolonged starvation depending on transcriptional upregulation and autophagy-derived amino acids

(2014) Mayurbhai Himatbhai Sahani et al.   Autophagy

mTOR and autophagy in normal brain aging and caloric restriction ameliorating age-related cognition deficits

(2014) Fengying Yang et al.   BEHAVIOURAL BRAIN RESEARCH

Mechanism and Regulation of Autophagy and Its Role in Neuronal Diseases

(2014) Zhiping Hu et al.   MOLECULAR NEUROBIOLOGY

Rapamycin Is Neuroprotective in a Rat Chronic Hypertensive Glaucoma Model

(2014) Wenru Su et al.   PLoS One

Activation of autophagy and paraptosis in retinal ganglion cells after retinal ischemia and reperfusion injury in rats

(2014) TING WEI et al.   Experimental and Therapeutic Medicine

mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6

(2013) Francesca Nazio et al.   NATURE CELL BIOLOGY

Impairment of Neuronal Glutamate Uptake and Modulation of the Glutamate Transporter GLT-1 Induced by Retinal Ischemia

(2013) Rossella Russo et al.   PLoS One

Axonal protection by Nmnat3 overexpression with involvement of autophagy in optic nerve degeneration

(2013) Y Kitaoka et al.   Cell Death & Disease

Circadian regulation of autophagy rhythm through transcription factor C/EBPβ

(2012) Di Ma et al.   Autophagy

Neuroprotective effect of melatonin against hypoxia-induced retinal ganglion cell death in neonatal rats

(2012) Charanjit Kaur et al.   JOURNAL OF PINEAL RESEARCH

Autophagy and Neuronal Cell Death in Neurological Disorders

(2012) R. A. Nixon et al.   Cold Spring Harbor Perspectives in Biology

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

AMPK and mTOR coordinate the regulation of Ulk1 and mammalian autophagy initiation

(2011) Libin Shang et al.   Autophagy

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR

(2011) Dan Egan et al.   Autophagy

Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice

(2011) N Rodríguez-Muela et al.   CELL DEATH AND DIFFERENTIATION

Retinal ganglion cell death is induced by microglia derived pro-inflammatory cytokines in the hypoxic neonatal retina

(2011) Viswanathan Sivakumar et al.   JOURNAL OF PATHOLOGY

Glaucoma

(2011) Harry A Quigley   LANCET

Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks

(2011) S. Alers et al.   MOLECULAR AND CELLULAR BIOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Activation of Autophagy in a Rat Model of Retinal Ischemia following High Intraocular Pressure

(2011) Antonio Piras et al.   PLoS One

Acute retinal arterial occlusive disorders

(2011) Sohan Singh Hayreh   PROGRESS IN RETINAL AND EYE RESEARCH

Calpain-mediated cleavage of Beclin-1 and autophagy deregulation following retinal ischemic injury in vivo

(2011) R Russo et al.   Cell Death & Disease

Short-term fasting induces profound neuronal autophagy

(2010) Mehrdad Alirezaei et al.   Autophagy

Autophagy for tissue homeostasis and neuroprotection

(2010) Guillermo Mariño et al.   CURRENT OPINION IN CELL BIOLOGY

Mitochondria: Their role in ganglion cell death and survival in primary open angle glaucoma

(2010) Neville N. Osborne   EXPERIMENTAL EYE RESEARCH

The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy

(2010) Sabrina Di Bartolomeo et al.   JOURNAL OF CELL BIOLOGY

Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

(2010) Shomit Sengupta et al.   MOLECULAR CELL

The Beclin 1–VPS34 complex – at the crossroads of autophagy and beyond

(2010) Sarah F. Funderburk et al.   TRENDS IN CELL BIOLOGY

In search of an “autophagomometer”

(2009) David C. Rubinsztein et al.   Autophagy

Neural-specific Deletion of FIP200 Leads to Cerebellar Degeneration Caused by Increased Neuronal Death and Axon Degeneration

(2009) Chun-Chi Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

Modulation of pro-survival and death-associated pathways under retinal ischemia/reperfusion: effects of NMDA receptor blockade

(2008) R. Russo et al.   JOURNAL OF NEUROCHEMISTRY

Activation of autophagy in retinal ganglion cells

(2008) Seok Hwan Kim et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Retinal ganglion cells in diabetes

(2008) Timothy S. Kern et al.   JOURNAL OF PHYSIOLOGY-LONDON

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway

(2008) K. K. Park et al.   SCIENCE

Regulation of macroautophagy by mTOR and Beclin 1 complexes

(2007) Sophie Pattingre et al.   BIOCHIMIE