Bioderived materials that disarm the gut mucosal immune system: Potential lessons from commensal microbiota

Lower endoscopic delivery of freeze-dried intestinal microbiota results in more rapid and efficient engraftment than oral administration

(2021) Christopher Staley et al.   Scientific Reports

Refining Host-Pathogen Interactions: Organ-on-Chip Side of the Coin

(2021) Buket Baddal et al.   Pathogens

Regulatory T-cell therapy in Crohn’s disease: challenges and advances

(2020) Jennie N Clough et al.   GUT

Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine

(2020) Samantha Hsieh et al.   JOURNAL OF IMMUNOLOGY

Natural and Induced Tolerogenic Dendritic Cells

(2020) Courtney A. Iberg et al.   JOURNAL OF IMMUNOLOGY

A (1→6)-Branched (1→4)-β-d-Glucan from Grifola frondosa Inhibits Lipopolysaccharide-Induced Cytokine Production in RAW264.7 Macrophages by Binding to TLR2 Rather than Dectin-1 or CR3 Receptors

(2020) Chun-Han Su et al.   JOURNAL OF NATURAL PRODUCTS

Recent Advances in Encapsulation, Protection, and Oral Delivery of Bioactive Proteins and Peptides using Colloidal Systems

(2020) Sarah L. Perry et al.   MOLECULES

Molecules Produced by Probiotics and Intestinal Microorganisms with Immunomodulatory Activity

(2020) Susana Delgado et al.   Nutrients

Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model

(2020) Magdalena Kasendra et al.   eLife

The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication

(2020) Ygor Parladore Silva et al.   Frontiers in Endocrinology

Mucins and the Microbiome

(2020) Gunnar C. Hansson   Annual Review of Biochemistry

Exopolysaccharide from Lactobacillus rhamnosus KL37 Inhibits T Cell-dependent Immune Response in Mice

(2020) Bernadeta Nowak et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Interaction between microbiota and immunity in health and disease

(2020) Danping Zheng et al.   CELL RESEARCH

Deficiency of Prebiotic Fiber and Insufficient Signaling Through Gut Metabolite-Sensing Receptors Leads to Cardiovascular Disease

(2020) David M. Kaye et al.   CIRCULATION

Short-chain fatty acid, acylation and cardiovascular diseases

(2020) Xiao-Feng Chen et al.   CLINICAL SCIENCE

Microbiota changes induced by microencapsulated sodium butyrate in patients with inflammatory bowel disease

(2020) Sonia Facchin et al.   NEUROGASTROENTEROLOGY AND MOTILITY

The Effect of Probiotics on the Production of Short-Chain Fatty Acids by Human Intestinal Microbiome

(2020) Paulina Markowiak-Kopeć et al.   Nutrients

Human Intestinal Mononuclear Phagocytes in Health and Inflammatory Bowel Disease

(2020) Charles Caër et al.   Frontiers in Immunology

Immunomodulatory Roles of Polysaccharide Capsules in the Intestine

(2020) Samantha A. Hsieh et al.   Frontiers in Immunology

Gut-Liver Physiomimetics Reveal Paradoxical Modulation of IBD-Related Inflammation by Short-Chain Fatty Acids

(2020) Martin Trapecar et al.   Cell Systems

The Role of the Gut Microbiome in Colorectal Cancer Development and Therapy Response

(2020) Lidia Sánchez-Alcoholado et al.   Cancers

The Exopolysaccharide of Lactobacillus fermentum UCO-979C Is Partially Involved in Its Immunomodulatory Effect and Its Ability to Improve the Resistance against Helicobacter pylori Infection

(2020) Valeria Garcia-Castillo et al.   Microorganisms

Microbiome-based stratification to guide dietary interventions to improve human health

(2020) Zhuang Liu et al.   NUTRITION RESEARCH

Microbiome response to diet: focus on obesity and related diseases

(2020) Nathalie M. Delzenne et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Therapeutic Potential of the Intestinal Microbiota for Immunomodulation of Food Allergies

(2020) Luisa Kreft et al.   Frontiers in Immunology

Commensal Obligate Anaerobic Bacteria and Health: Production, Storage, and Delivery Strategies

(2020) José Carlos Andrade et al.   Frontiers in Bioengineering and Biotechnology

Human Microphysiological Models of Intestinal Tissue and Gut Microbiome

(2020) Steven N. Steinway et al.   Frontiers in Bioengineering and Biotechnology

Lactate Exposure Promotes Immunosuppressive Phenotypes in Innate Immune Cells

(2020) Rapeepat Sangsuwan et al.   Cellular and Molecular Bioengineering

Mucus barrier, mucins and gut microbiota: the expected slimy partners?

(2020) Paola Paone et al.   GUT

Faecal microbiota transplantation for Clostridioides difficile: mechanisms and pharmacology

(2020) Alexander Khoruts et al.   Nature Reviews Gastroenterology & Hepatology

Immune System Modulations by Products of the Gut Microbiota

(2020) Thierry Chénard et al.   Vaccines

Functions of Macrophages in the Maintenance of Intestinal Homeostasis

(2019) Shuai Wang et al.   Journal of Immunology Research

Identification of the novel role of butyrate as AhR ligand in human intestinal epithelial cells

(2019) Ludovica Marinelli et al.   Scientific Reports

The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages

(2019) Julie Schulthess et al.   IMMUNITY

T lymphocytes in the intestinal mucosa: defense and tolerance

(2019) Hongdi Ma et al.   Cellular & Molecular Immunology

Leaky gut: mechanisms, measurement and clinical implications in humans

(2019) Michael Camilleri   GUT

Exopolysaccharide-Producing Bifidobacterium adolescentis Strains with Similar Adhesion Property Induce Differential Regulation of Inflammatory Immune Response in Treg/Th17 Axis of DSS-Colitis Mice

(2019) Rui Yu et al.   Nutrients

Cutting Edge: Probiotics and Fecal Microbiota Transplantation in Immunomodulation

(2019) Wenjie Zeng et al.   Journal of Immunology Research

A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip

(2019) Sasan Jalili-Firoozinezhad et al.   Nature Biomedical Engineering

The Intestine Harbors Functionally Distinct Homeostatic Tissue-Resident and Inflammatory Th17 Cells

(2019) Sara Omenetti et al.   IMMUNITY

Monosaccharide composition influence and immunomodulatory effects of probiotic exopolysaccharides

(2019) Yo-Chia Chen et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Durable Long-Term Bacterial Engraftment following Encapsulated Fecal Microbiota Transplantation To Treat Clostridium difficile Infection

(2019) Christopher Staley et al.   mBio

Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis

(2019) Chandran Ramakrishna et al.   Nature Communications

Probiotics in Food Systems: Significance and Emerging Strategies Towards Improved Viability and Delivery of Enhanced Beneficial Value

(2019) Antonia Terpou et al.   Nutrients

Targeting Adenosine in Cancer Immunotherapy to Enhance T-Cell Function

(2019) Selena Vigano et al.   Frontiers in Immunology

Potential of Prebiotic Butyrogenic Fibers in Parkinson's Disease

(2019) Thaisa M. Cantu-Jungles et al.   Frontiers in Neurology

Potential for enriching next-generation health-promoting gut bacteria through prebiotics and other dietary components

(2019) Cathy Lordan et al.   Gut Microbes

Postbiotics and Their Potential Applications in Early Life Nutrition and Beyond

(2019) Wegh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Photopatterned Membranes and Chemical Gradients Enable Scalable Phenotypic Organization of Primary Human Colon Epithelial Models

(2019) Samuel S. Hinman et al.   ANALYTICAL CHEMISTRY

Intestinal Microbiota-Associated Metabolites: Crucial Factors in the Effectiveness of Herbal Medicines and Diet Therapies

(2019) Yiliang Wang et al.   Frontiers in Physiology

Delivery to the gut microbiota: A rapidly proliferating research field

(2019) Adi Seifert et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

Inulin alleviates inflammation of alcoholic liver disease via SCFAs-inducing suppression of M1 and facilitation of M2 macrophages in mice

(2019) Zhen Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Symbionts exploit complex signaling to educate the immune system

(2019) Deniz Erturk-Hasdemir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbiota-Derived Indole Metabolites Promote Human and Murine Intestinal Homeostasis through Regulation of Interleukin-10 Receptor

(2018) Erica E. Alexeev et al.   AMERICAN JOURNAL OF PATHOLOGY

Finding a needle in a haystack: Bacteroides fragilis polysaccharide A as the archetypical symbiosis factor

(2018) Deniz Erturk-Hasdemir et al.   Annals of the New York Academy of Sciences

Tumor-Repopulating Cells Induce PD-1 Expression in CD8 + T Cells by Transferring Kynurenine and AhR Activation

(2018) Yuying Liu et al.   CANCER CELL

Co-microencapsulation of Lactobacillus plantarum and DHA fatty acid in alginate-pectin-gelatin biocomposites

(2018) Asma Sadat Vaziri et al.   CARBOHYDRATE POLYMERS

In vitro fermentation of Cookeina speciosa glucans stimulates the growth of the butyrogenic Clostridium cluster XIVa in a targeted way

(2018) Thaisa Moro Cantu-Jungles et al.   CARBOHYDRATE POLYMERS

Development of Novel Indole-3-Aldehyde–Loaded Gastro-Resistant Spray-Dried Microparticles for Postbiotic Small Intestine Local Delivery

(2018) Matteo Puccetti et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Synbiotic encapsulation of probiotic Latobacillus plantarum by alginate -arabinoxylan composite microspheres

(2018) Yue Wu et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

GPR43 mediates microbiota metabolite SCFA regulation of antimicrobial peptide expression in intestinal epithelial cells via activation of mTOR and STAT3

(2018) Ye Zhao et al.   Mucosal Immunology

Microglial control of astrocytes in response to microbial metabolites

(2018) Veit Rothhammer et al.   NATURE

Apoptotic cell–induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans

(2018) Rahul Shinde et al.   NATURE IMMUNOLOGY

Translocation of a gut pathobiont drives autoimmunity in mice and humans

(2018) S. Manfredo Vieira et al.   SCIENCE

Postbiotics: An evolving term within the functional foods field

(2018) J.E. Aguilar-Toalá et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

The Intestinal Epithelium: Central Coordinator of Mucosal Immunity

(2018) Joannie M. Allaire et al.   TRENDS IN IMMUNOLOGY

Intestinal Intraepithelial Lymphocytes: Sentinels of the Mucosal Barrier

(2018) Danyvid Olivares-Villagómez et al.   TRENDS IN IMMUNOLOGY

FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming

(2018) Ivo S. Hansen et al.   Nature Communications

Impact of the Gut Microbiota on Intestinal Immunity Mediated by Tryptophan Metabolism

(2018) Jing Gao et al.   Frontiers in Cellular and Infection Microbiology

Immunomodulatory bonds of the partnership between dendritic cells and T cells

(2018) Daniel Hawiger et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Microbial tryptophan catabolites in health and disease

(2018) Henrik M. Roager et al.   Nature Communications

Interconnected Microphysiological Systems for Quantitative Biology and Pharmacology Studies

(2018) Collin D. Edington et al.   Scientific Reports

Primary Cell-Derived Intestinal Models: Recapitulating Physiology

(2018) Johanna S. Dutton et al.   TRENDS IN BIOTECHNOLOGY

The Aryl Hydrocarbon Receptor: Connecting Immunity to the Microenvironment

(2018) Rahul Shinde et al.   TRENDS IN IMMUNOLOGY

Interactions of Surface Exopolysaccharides From Bifidobacterium and Lactobacillus Within the Intestinal Environment

(2018) Nuria Castro-Bravo et al.   Frontiers in Microbiology

Intestinal Dendritic Cells in Health and Gut Inflammation

(2018) Andrew J. Stagg   Frontiers in Immunology

Commensal Bacteria-Specific CD4+ T Cell Responses in Health and Disease

(2018) Chiara Sorini et al.   Frontiers in Immunology

Homeostatic Immunity and the Microbiota

(2017) Yasmine Belkaid et al.   IMMUNITY

Altered Gut Microbiota in a Mouse Model of Alzheimer’s Disease

(2017) Ling Zhang et al.   JOURNAL OF ALZHEIMERS DISEASE

Design of a potentially prebiotic and responsive encapsulation material for probiotic bacteria based on chitosan and sulfated β-glucan

(2017) Cigdem Yucel Falco et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Maternal High Fiber Diet during Pregnancy and Lactation Influences Regulatory T Cell Differentiation in Offspring in Mice

(2017) Akihito Nakajima et al.   JOURNAL OF IMMUNOLOGY

The Influence of the Microbiome on Allergic Sensitization to Food

(2017) Catherine H. Plunkett et al.   JOURNAL OF IMMUNOLOGY

Molecular and biopharmaceutical investigation of alginate–inulin synbiotic coencapsulation of probiotic to target the colon

(2017) Abdelbasset Atia et al.   JOURNAL OF MICROENCAPSULATION

Beneficial effects on host energy metabolism of short-chain fatty acids and vitamins produced by commensal and probiotic bacteria

(2017) Jean Guy LeBlanc et al.   Microbial Cell Factories

The nasal and gut microbiome in Parkinson's disease and idiopathic rapid eye movement sleep behavior disorder

(2017) Anna Heintz-Buschart et al.   MOVEMENT DISORDERS

Diversity and functions of intestinal mononuclear phagocytes

(2017) T Joeris et al.   Mucosal Immunology

Gut microbiota and IBD: causation or correlation?

(2017) Josephine Ni et al.   Nature Reviews Gastroenterology & Hepatology

Macrophages in gastrointestinal homeostasis and inflammation

(2017) John R. Grainger et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Chitosan oligosaccharide: Biological activities and potential therapeutic applications

(2017) Chatchai Muanprasat et al.   PHARMACOLOGY & THERAPEUTICS

Gut cell metabolism shapes the microbiome

(2017) Patrice D. Cani   SCIENCE

Lactobacillus reuteriinduces gut intraepithelial CD4+CD8αα+T cells

(2017) Luisa Cervantes-Barragan et al.   SCIENCE

Microbiota-activated PPAR-γ signaling inhibits dysbiotic Enterobacteriaceae expansion

(2017) Mariana X. Byndloss et al.   SCIENCE

Emulating Host-Microbiome Ecosystem of Human Gastrointestinal Tract in Vitro

(2017) Gun-Seok Park et al.   Stem Cell Reviews and Reports

TCDD, FICZ, and Other High Affinity AhR Ligands Dose-Dependently Determine the Fate of CD4+ T Cell Differentiation

(2017) Allison K Ehrlich et al.   TOXICOLOGICAL SCIENCES

Gut microbiome interactions with drug metabolism, efficacy, and toxicity

(2017) Ian D. Wilson et al.   Translational Research

Aging Gut Microbiota at the Cross-Road between Nutrition, Physical Frailty, and Sarcopenia: Is There a Gut–Muscle Axis?

(2017) Andrea Ticinesi et al.   Nutrients

Short Chain Fatty Acids in the Colon and Peripheral Tissues: A Focus on Butyrate, Colon Cancer, Obesity and Insulin Resistance

(2017) Sean McNabney et al.   Nutrients

Emulating Host-Microbiome Ecosystem of Human Gastrointestinal Tract in Vitro

(2017) Gun-Seok Park et al.   Stem Cell Reviews and Reports

High frequency of intestinal T H 17 cells correlates with microbiota alterations and disease activity in multiple sclerosis

(2017) Ilaria Cosorich et al.   Science Advances

An orally administered butyrate-releasing derivative reduces neutrophil recruitment and inflammation in dextran sulphate sodium-induced murine colitis

(2016) Raffaele Simeoli et al.   BRITISH JOURNAL OF PHARMACOLOGY

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

Diverse Intestinal Bacteria Contain Putative Zwitterionic Capsular Polysaccharides with Anti-inflammatory Properties

(2016) C. Preston Neff et al.   Cell Host & Microbe

Inflammatory Bowel Disease Affects the Outcome of Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection

(2016) Alexander Khoruts et al.   Clinical Gastroenterology and Hepatology

Wheat bran promotes enrichment within the human colonic microbiota of butyrate-producing bacteria that release ferulic acid

(2016) Sylvia H. Duncan et al.   ENVIRONMENTAL MICROBIOLOGY

The Heterogeneity of Ly6Chi Monocytes Controls Their Differentiation into iNOS+ Macrophages or Monocyte-Derived Dendritic Cells

(2016) Shinelle Menezes et al.   IMMUNITY

Tryptophan Metabolism in Allergic Disorders

(2016) Johanna M. Gostner et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Absence of MHC class II on cDCs results in microbial-dependent intestinal inflammation

(2016) Jakob Loschko et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases

(2016) Mingming Sun et al.   JOURNAL OF GASTROENTEROLOGY

Butyrate suppresses murine mast cell proliferation and cytokine production through inhibiting histone deacetylase

(2016) Hanying Zhang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Indole-3-carbinol induces tumor cell death: function follows form

(2016) Bryant W. Megna et al.   JOURNAL OF SURGICAL RESEARCH

mTORC1 mediates peptidoglycan induced inflammatory cytokines expression and NF-κB activation in macrophages

(2016) Nyamtsengel Vangan et al.   MICROBIAL PATHOGENESIS

Classical dendritic cells are required for dietary antigen–mediated induction of peripheral Treg cells and tolerance

(2016) Daria Esterházy et al.   NATURE IMMUNOLOGY

Microbial short chain fatty acid metabolites lower blood pressure via endothelial G protein-coupled receptor 41

(2016) Niranjana Natarajan et al.   PHYSIOLOGICAL GENOMICS

Tolerogenic nanoparticles inhibit T cell–mediated autoimmunity through SOCS2

(2016) Ada Yeste et al.   Science Signaling

Tolerogenic dendritic cells

(2016) Maisa C. Takenaka et al.   Seminars in Immunopathology

SCFA Receptors in Pancreatic β Cells: Novel Diabetes Targets?

(2016) Medha Priyadarshini et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

AHR Function in Lymphocytes: Emerging Concepts

(2016) Liang Zhou   TRENDS IN IMMUNOLOGY

Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways

(2016) Jian Tan et al.   Cell Reports

Rapid and Efficient Generation of Regulatory T Cells to Commensal Antigens in the Periphery

(2016) Katherine Nutsch et al.   Cell Reports

Effect of a Ropy Exopolysaccharide-Producing Bifidobacterium animalis subsp. lactis Strain Orally Administered on DSS-Induced Colitis Mice Model

(2016) Claudio Hidalgo-Cantabrana et al.   Frontiers in Microbiology

Bifidobacteria and Butyrate-Producing Colon Bacteria: Importance and Strategies for Their Stimulation in the Human Gut

(2016) Audrey Rivière et al.   Frontiers in Microbiology

Intestinal Short Chain Fatty Acids and their Link with Diet and Human Health

(2016) David Ríos-Covián et al.   Frontiers in Microbiology

Tolerogenic nanoparticles inhibit T cell–mediated autoimmunity through SOCS2

(2016) Ada Yeste et al.   Science Signaling

Molecular Mechanisms of Induction of Tolerant and Tolerogenic Intestinal Dendritic Cells in Mice

(2016) Alex Steimle et al.   Journal of Immunology Research

How gut microbes talk to organs: The role of endocrine and nervous routes

(2016) Patrice D. Cani et al.   Molecular Metabolism

Fecal Microbiota Transplantation forClostridium difficileInfection

(2015) Dimitri Drekonja et al.   ANNALS OF INTERNAL MEDICINE

Microbiota-Mediated Inflammation and Antimicrobial Defense in the Intestine

(2015) Silvia Caballero et al.   Annual Review of Immunology

An IL-23R/IL-22 Circuit Regulates Epithelial Serum Amyloid A to Promote Local Effector Th17 Responses

(2015) Teruyuki Sano et al.   CELL

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

(2015) Marc van de Wetering et al.   CELL

Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells

(2015) Koji Atarashi et al.   CELL

Establishing a Fecal Microbiota Transplant Service for the Treatment ofClostridium difficileInfection

(2015) Samuel P. Costello et al.   CLINICAL INFECTIOUS DISEASES

Dietary Polyphenols Promote Growth of the Gut BacteriumAkkermansia muciniphilaand Attenuate High-Fat Diet–Induced Metabolic Syndrome

(2015) Diana E. Roopchand et al.   DIABETES

Oral insulin delivery systems using chitosan-based formulation: a review

(2015) Khalid Al Rubeaan et al.   Expert Opinion on Drug Delivery

Identification of an anti-inflammatory protein fromFaecalibacterium prausnitzii, a commensal bacterium deficient in Crohn’s disease

(2015) E Quévrain et al.   GUT

Short, but Smart: SCFAs Train T Cells in the Gut to Fight Autoimmunity in the Brain

(2015) Yangzom D. Bhutia et al.   IMMUNITY

Lactate and short chain fatty acids produced by microbial fermentation downregulate proinflammatory responses in intestinal epithelial cells and myeloid cells

(2015) Carolina Iraporda et al.   IMMUNOBIOLOGY

Red Ginseng and Semen Coicis can improve the structure of gut microbiota and relieve the symptoms of ulcerative colitis

(2015) Mingzhang Guo et al.   JOURNAL OF ETHNOPHARMACOLOGY

New developments in goblet cell mucus secretion and function

(2015) G M H Birchenough et al.   Mucosal Immunology

Gut biogeography of the bacterial microbiota

(2015) Gregory P. Donaldson et al.   NATURE REVIEWS MICROBIOLOGY

Butyrate modulates bacterial adherence on LS174T human colorectal cells by stimulating mucin secretion and MAPK signaling pathway

(2015) Tae-Hwan Jung et al.   Nutrition Research and Practice

Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip

(2015) Hyun Jung Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance

(2015) S. Yang et al.   SCIENCE

Proteobacteria: microbial signature of dysbiosis in gut microbiota

(2015) Na-Ri Shin et al.   TRENDS IN BIOTECHNOLOGY

Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites

(2015) Alison N. Thorburn et al.   Nature Communications

Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome

(2015) Laurence Macia et al.   Nature Communications

Neuroprotective Effects ofClostridium butyricumagainst Vascular Dementia in Mice via Metabolic Butyrate

(2015) Jiaming Liu et al.   Biomed Research International

Faecalibacterium prausnitzii Strain HTF-F and Its Extracellular Polymeric Matrix Attenuate Clinical Parameters in DSS-Induced Colitis

(2015) Oriana Rossi et al.   PLoS One

Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles

(2015) Troy D. Hubbard et al.   Scientific Reports

A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increasedAkkermansiaspp. population in the gut microbiota of mice

(2014) Fernando F Anhê et al.   GUT

Interleukin-10 Receptor Signaling in Innate Immune Cells Regulates Mucosal Immune Tolerance and Anti-Inflammatory Macrophage Function

(2014) Dror S. Shouval et al.   IMMUNITY

Oral Infection Drives a Distinct Population of Intestinal Resident Memory CD8+ T Cells with Enhanced Protective Function

(2014) Brian S. Sheridan et al.   IMMUNITY

Macrophage-Restricted Interleukin-10 Receptor Deficiency, but Not IL-10 Deficiency, Causes Severe Spontaneous Colitis

(2014) Ehud Zigmond et al.   IMMUNITY

Diet, Metabolites, and “Western-Lifestyle” Inflammatory Diseases

(2014) Alison N. Thorburn et al.   IMMUNITY

Oral Tolerance Can Be Established via Gap Junction Transfer of Fed Antigens from CX3CR1+ Macrophages to CD103+ Dendritic Cells

(2014) Elisa Mazzini et al.   IMMUNITY

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

(2014) Nagendra Singh et al.   IMMUNITY

Macrophages in intestinal homeostasis and inflammation

(2014) Calum C. Bain et al.   IMMUNOLOGICAL REVIEWS

Structural modulation of gut microbiota during alleviation of type 2 diabetes with a Chinese herbal formula

(2014) Jia Xu et al.   ISME Journal

Lymph-borne CD8α+ dendritic cells are uniquely able to cross-prime CD8+ T cells with antigen acquired from intestinal epithelial cells

(2014) V Cerovic et al.   Mucosal Immunology

Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells

(2014) G Bakdash et al.   Mucosal Immunology

Aryl hydrocarbon receptor control of a disease tolerance defence pathway

(2014) Alban Bessede et al.   NATURE

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

(2014) Calum C Bain et al.   NATURE IMMUNOLOGY

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

(2014) Aurélien Trompette et al.   NATURE MEDICINE

The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic

(2014) Colin Hill et al.   Nature Reviews Gastroenterology & Hepatology

The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition

(2014) Pamela V. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The gut microbiota influences blood-brain barrier permeability in mice

(2014) V. Braniste et al.   Science Translational Medicine

Gut Microbiota-Derived Short-Chain Fatty Acids, T Cells, and Inflammation

(2014) Chang H. Kim et al.   Immune Network

Paneth Cells: Maestros of the Small Intestinal Crypts

(2013) Hans C. Clevers et al.   Annual Review of Physiology

Colonic bacterial metabolites and human health

(2013) Wendy R Russell et al.   CURRENT OPINION IN MICROBIOLOGY

Short-Chain Fatty Acids Activate GPR41 and GPR43 on Intestinal Epithelial Cells to Promote Inflammatory Responses in Mice

(2013) Myung H. Kim et al.   GASTROENTEROLOGY

Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

(2013) Teresa Zelante et al.   IMMUNITY

IRF4 Transcription-Factor-Dependent CD103+CD11b+ Dendritic Cells Drive Mucosal T Helper 17 Cell Differentiation

(2013) Emma K. Persson et al.   IMMUNITY

Luminal Bacteria Recruit CD103+ Dendritic Cells into the Intestinal Epithelium to Sample Bacterial Antigens for Presentation

(2013) Julia Farache et al.   IMMUNITY

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

(2013) Gijs den Besten et al.   JOURNAL OF LIPID RESEARCH

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

Microbiota restricts trafficking of bacteria to mesenteric lymph nodes by CX3CR1hi cells

(2013) Gretchen E. Diehl et al.   NATURE

Bacterial colonization factors control specificity and stability of the gut microbiota

(2013) S. Melanie Lee et al.   NATURE

Growing Self-Organizing Mini-Guts from a Single Intestinal Stem Cell: Mechanism and Applications

(2013) T. Sato et al.   SCIENCE

Stratification and compartmentalisation of immunoglobulin responses to commensal intestinal microbes

(2013) Andrew J. Macpherson et al.   SEMINARS IN IMMUNOLOGY

Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells

(2012) Mary A. Zimmerman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Animal models of chronic liver diseases

(2012) Yan Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Effects of cereal β-glucans and enzyme inclusion on the porcine gastrointestinal tract microbiota

(2012) Padraigin Murphy et al.   ANAEROBE

Interaction of Bifidobacterium bifidum LMG13195 with HT29 Cells Influences Regulatory-T-Cell-Associated Chemokine Receptor Expression

(2012) Patricia López et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis

(2012) Samira Tamoutounour et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin 23 Production by Intestinal CD103+CD11b+ Dendritic Cells in Response to Bacterial Flagellin Enhances Mucosal Innate Immune Defense

(2012) Melissa A. Kinnebrew et al.   IMMUNITY

Inflammation switches the differentiation program of Ly6Chimonocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon

(2012) Aymeric Rivollier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dendritic Cell-Specific Disruption of TGF-  Receptor II Leads to Altered Regulatory T Cell Phenotype and Spontaneous Multiorgan Autoimmunity

(2012) R. Ramalingam et al.   JOURNAL OF IMMUNOLOGY

Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors

(2012) C C Bain et al.   Mucosal Immunology

Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine

(2012) Jeremiah R. McDole et al.   NATURE

Intestinal CX3C chemokine receptor 1high (CX3CR1high) myeloid cells prevent T-cell-dependent colitis

(2012) H. Kayama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanoparticle-mediated codelivery of myelin antigen and a tolerogenic small molecule suppresses experimental autoimmune encephalomyelitis

(2012) A. Yeste et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beneficial Effects of Probiotic Bifidobacterium and Galacto-Oligosaccharide in Patients with Ulcerative Colitis: A Randomized Controlled Study

(2011) Hideki Ishikawa et al.   DIGESTION

Intestinal Tolerance Requires Gut Homing and Expansion of FoxP3+ Regulatory T Cells in the Lamina Propria

(2011) Usriansyah Hadis et al.   IMMUNITY

Retinoic acid induces homing of protective T and B cells to the gut after subcutaneous immunization in mice

(2011) Swantje I. Hammerschmidt et al.   JOURNAL OF CLINICAL INVESTIGATION

Dietary modulation of clostridial cluster XIVa gut bacteria (Roseburia spp.) by chitin–glucan fiber improves host metabolic alterations induced by high-fat diet in mice

(2011) Audrey M. Neyrinck et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination

(2011) Kerstin Berer et al.   NATURE

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Increased Intestinal Permeability Correlates with Sigmoid Mucosa alpha-Synuclein Staining and Endotoxin Exposure Markers in Early Parkinson's Disease

(2011) Christopher B. Forsyth et al.   PLoS One

Treg-inducing membrane vesicles from Bifidobacterium bifidum LMG13195 as potential adjuvants in immunotherapy

(2011) Patricia López et al.   VACCINE

Clinical trial: the microbiological and immunological effects of synbiotic consumption - a randomized double-blind placebo-controlled study in active Crohn’s disease

(2010) H. Steed et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Gut-Residing Segmented Filamentous Bacteria Drive Autoimmune Arthritis via T Helper 17 Cells

(2010) Hsin-Jung Wu et al.   IMMUNITY

An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

(2010) J. D. Mezrich et al.   JOURNAL OF IMMUNOLOGY

Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism

(2010) N. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon

(2010) L. Peyrin-Biroulet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis

(2010) F. J. Quintana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine

(2009) Petra Louis et al.   FEMS MICROBIOLOGY LETTERS

Differential Roles of Interleukin-17A and -17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses

(2009) Harumichi Ishigame et al.   IMMUNITY

Human CD14+ Macrophages in Intestinal Lamina Propria Exhibit Potent Antigen-Presenting Ability

(2009) N. Kamada et al.   JOURNAL OF IMMUNOLOGY

Butyrate Enhances the Intestinal Barrier by Facilitating Tight Junction Assembly via Activation of AMP-Activated Protein Kinase in Caco-2 Cell Monolayers

(2009) Luying Peng et al.   JOURNAL OF NUTRITION

l-Tryptophan exhibits therapeutic function in a porcine model of dextran sodium sulfate (DSS)-induced colitis

(2009) Connie J. Kim et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Effects of chronic exposure to DDT and TCDD on disease activity in murine systemic lupus erythematosus

(2009) J Li et al.   LUPUS

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

(2009) Kendle M. Maslowski et al.   NATURE

A randomized controlled trial on the efficacy of synbiotic versus probiotic or prebiotic treatment to improve the quality of life in patients with ulcerative colitis

(2009) Shunji Fujimori et al.   NUTRITION

Intestinal macrophages: differentiation and involvement in intestinal immunopathologies

(2009) Benjamin Weber et al.   Seminars in Immunopathology

Innate and Adaptive Interleukin-22 Protects Mice from Inflammatory Bowel Disease

(2008) Lauren A. Zenewicz et al.   IMMUNITY

The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation

(2008) Wenjun Ouyang et al.   IMMUNITY

Small intestinal CD103+dendritic cells display unique functional properties that are conserved between mice and humans

(2008) Elin Jaensson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5

(2008) Satoshi Uematsu et al.   NATURE IMMUNOLOGY

Butyrate and trichostatin A attenuate nuclear factor κB activation and tumor necrosis factor α secretion and increase prostaglandin E2 secretion in human peripheral blood mononuclear cells

(2008) Makoto Usami et al.   NUTRITION RESEARCH