Emulating Host-Microbiome Ecosystem of Human Gastrointestinal Tract in Vitro

Faecalibacterium prausnitzii: from microbiology to diagnostics and prognostics

(2017) Mireia Lopez-Siles et al.   ISME Journal

Brain–gut–microbiota axis — mood, metabolism and behaviour

(2017) Timothy G. Dinan et al.   Nature Reviews Gastroenterology & Hepatology

Gut microbiome interactions with drug metabolism, efficacy, and toxicity

(2017) Ian D. Wilson et al.   Translational Research

Soft 3D-Printed Phantom of the Human Kidney with Collecting System

(2016) Fabian Adams et al.   ANNALS OF BIOMEDICAL ENGINEERING

Modeling Development and Disease with Organoids

(2016) Hans Clevers   CELL

Engineering Stem Cell Organoids

(2016) Xiaolei Yin et al.   Cell Stem Cell

VSL#3 Probiotic Stimulates T-cell Protein Tyrosine Phosphatase–mediated Recovery of IFN-γ–induced Intestinal Epithelial Barrier Defects

(2016) Moorthy Krishnan et al.   INFLAMMATORY BOWEL DISEASES

Poly(N -isopropylacrylamide) hydrogel/chitosan scaffold hybrid for three-dimensional stem cell culture and cartilage tissue engineering

(2016) Amir Mellati et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Organoids as an in vitro model of human development and disease

(2016) Aliya Fatehullah et al.   NATURE CELL BIOLOGY

Population-level analysis of gut microbiome variation

(2016) Gwen Falony et al.   SCIENCE

Replication of human noroviruses in stem cell-derived human enteroids

(2016) K. Ettayebi et al.   SCIENCE

A microfluidics-based in vitro model of the gastrointestinal human–microbe interface

(2016) Pranjul Shah et al.   Nature Communications

Farewell to Animal Testing: Innovations on Human Intestinal Microphysiological Systems

(2016) Tae Kang et al.   Micromachines

Human Vascular Microphysiological System for in vitro Drug Screening

(2016) C. E. Fernandez et al.   Scientific Reports

Organoid Models of Human and Mouse Ductal Pancreatic Cancer

(2015) Sylvia F. Boj et al.   CELL

Control of Brain Development, Function, and Behavior by the Microbiome

(2015) Timothy R. Sampson et al.   Cell Host & Microbe

The role of the gut microbiome in the healthy adult status

(2015) Valeria D’Argenio et al.   CLINICA CHIMICA ACTA

In Vitro Expansion of Human Gastric Epithelial Stem Cells and Their Responses to Bacterial Infection

(2015) Sina Bartfeld et al.   GASTROENTEROLOGY

Update on Fecal Microbiota Transplantation 2015: Indications, Methodologies, Mechanisms, and Outlook

(2015) Colleen R. Kelly et al.   GASTROENTEROLOGY

The Precision Medicine Initiative

(2015) Euan A. Ashley   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Measuring direct current trans-epithelial electrical resistance in organ-on-a-chip microsystems

(2015) Mathieu Odijk et al.   LAB ON A CHIP

Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

(2015) Minoru Takasato et al.   NATURE

Immunopathogenesis of IBD: current state of the art

(2015) Heitor S. P. de Souza et al.   Nature Reviews Gastroenterology & Hepatology

Sequencing and beyond: integrating molecular 'omics' for microbial community profiling

(2015) Eric A. Franzosa et al.   NATURE REVIEWS MICROBIOLOGY

Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip

(2015) Hyun Jung Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A simple coculture system shows mutualism between anaerobic faecalibacteria and epithelial Caco-2 cells

(2015) Mehdi Sadaghian Sadabad et al.   Scientific Reports

Robust bioengineered 3D functional human intestinal epithelium

(2015) Ying Chen et al.   Scientific Reports

Bacterial Composition of the Human Upper Gastrointestinal Tract Microbiome Is Dynamic and Associated with Genomic Instability in a Barrett’s Esophagus Cohort

(2015) Alevtina Gall et al.   PLoS One

Injectable In Situ Self-Cross-Linking Hydrogels Based on Poly(l-glutamic acid) and Alginate for Cartilage Tissue Engineering

(2014) Shifeng Yan et al.   BIOMACROMOLECULES

The influence of a spatiotemporal 3D environment on endothelial cell differentiation of human induced pluripotent stem cells

(2014) Sophia Zhang et al.   BIOMATERIALS

The HMI™ module: a new tool to study the Host-Microbiota Interaction in the human gastrointestinal tract in vitro

(2014) Massimo Marzorati et al.   BMC MICROBIOLOGY

Identification of Multipotent Luminal Progenitor Cells in Human Prostate Organoid Cultures

(2014) Wouter R. Karthaus et al.   CELL

Blood–brain barrier models and their relevance for a successful development of CNS drug delivery systems: A review

(2014) Joana Bicker et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Human enteroids as an ex-vivo model of host–pathogen interactions in the gastrointestinal tract

(2014) Jennifer Foulke-Abel et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The Microbiome in Inflammatory Bowel Disease: Current Status and the Future Ahead

(2014) Aleksandar D. Kostic et al.   GASTROENTEROLOGY

Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays

(2014) Kelli L VanDussen et al.   GUT

An Overview of Poly(lactic-co-glycolic) Acid (PLGA)-Based Biomaterials for Bone Tissue Engineering

(2014) Piergiorgio Gentile et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PEG-Poly(l-alanine) Thermogel As a 3D Scaffold of Bone-Marrow-Derived Mesenchymal Stem Cells

(2014) Min Hee Park et al.   MACROMOLECULAR BIOSCIENCE

Gut microbiota are related to Parkinson's disease and clinical phenotype

(2014) Filip Scheperjans et al.   MOVEMENT DISORDERS

Modelling human development and disease in pluripotent stem-cell-derived gastric organoids

(2014) Kyle W. McCracken et al.   NATURE

Organogenesis in a dish: Modeling development and disease using organoid technologies

(2014) M. A. Lancaster et al.   SCIENCE

Engineering De Novo Assembly of Fetal Pulmonary Organoids

(2014) Mark J. Mondrinos et al.   TISSUE ENGINEERING PART A

Phylogeny, culturing, and metagenomics of the human gut microbiota

(2014) Alan W. Walker et al.   TRENDS IN MICROBIOLOGY

3D Culture of Tonsil-Derived Mesenchymal Stem Cells in Poly(ethylene glycol)-Poly(l-alanine-co-l-phenyl alanine) Thermogel

(2014) Min Hee Park et al.   Advanced Healthcare Materials

Development of an in vitroperiodontal biofilm model for assessing antimicrobial and host modulatory effects of bioactive molecules

(2014) Emma Millhouse et al.   BMC Oral Health

Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation

(2013) Hyun Jung Kim et al.   Integrative Biology

Insights into the phylogeny and coding potential of microbial dark matter

(2013) Christian Rinke et al.   NATURE

The haplotype-resolved genome and epigenome of the aneuploid HeLa cancer cell line

(2013) Andrew Adey et al.   NATURE

Vascularized and functional human liver from an iPSC-derived organ bud transplant

(2013) Takanori Takebe et al.   NATURE

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

Next-generation sequencing: The future of molecular genetics in poultry production and food safety

(2013) S. Diaz-Sanchez et al.   POULTRY SCIENCE

Villification: How the Gut Gets Its Villi

(2013) A. E. Shyer et al.   SCIENCE

Growing Self-Organizing Mini-Guts from a Single Intestinal Stem Cell: Mechanism and Applications

(2013) T. Sato et al.   SCIENCE

Predicting and Manipulating Cardiac Drug Inactivation by the Human Gut Bacterium Eggerthella lenta

(2013) H. J. Haiser et al.   SCIENCE

The Gut Microbiome Modulates Colon Tumorigenesis

(2013) J. P. Zackular et al.   mBio

Complexation-Induced Biomimetic Long Range Fibrous Orientation in a Rigid-Flexible Block Copolymer Thermogel

(2012) Min Hee Park et al.   ADVANCED FUNCTIONAL MATERIALS

Standardized Frozen Preparation for Transplantation of Fecal Microbiota for Recurrent Clostridium difficile Infection

(2012) Matthew J Hamilton et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The gut anaerobe Faecalibacterium prausnitzii uses an extracellular electron shuttle to grow at oxic–anoxic interphases

(2012) M Tanweer Khan et al.   ISME Journal

Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow

(2012) Hyun Jung Kim et al.   LAB ON A CHIP

Learning about who we are

(2012) David A. Relman   NATURE

Functional interactions between the gut microbiota and host metabolism

(2012) Valentina Tremaroli et al.   NATURE

The role of the gut microbiota in nutrition and health

(2012) Harry J. Flint et al.   Nature Reviews Gastroenterology & Hepatology

Developing a metagenomic view of xenobiotic metabolism

(2012) Henry J. Haiser et al.   PHARMACOLOGICAL RESEARCH

Bioprinted Amniotic Fluid-Derived Stem Cells Accelerate Healing of Large Skin Wounds

(2012) Aleksander Skardal et al.   Stem Cells Translational Medicine

Differential Targeting of the E-Cadherin/β-Catenin Complex by Gram-Positive Probiotic Lactobacilli Improves Epithelial Barrier Function

(2011) Stephanie Hummel et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

Human nutrition, the gut microbiome and the immune system

(2011) Andrew L. Kau et al.   NATURE

Controlled gene expression in primary Lgr5 organoid cultures

(2011) Bon-Kyoung Koo et al.   NATURE METHODS

Advances and perspectives in in vitro human gut fermentation modeling

(2011) Amanda N. Payne et al.   TRENDS IN BIOTECHNOLOGY

Brain?Gut?Microbe Communication in Health and Disease

(2011) Sue Grenham et al.   Frontiers in Physiology

A microfluidic device for tissue biopsy culture and interrogation

(2010) Abigail Webster et al.   Analytical Methods

Bioactive modification of poly(ethylene glycol) hydrogels for tissue engineering

(2010) Junmin Zhu   BIOMATERIALS

Faecal microflora and β-glucuronidase expression are altered in an irinotecan-induced diarrhea model in rats

(2010) Andrea M Stringer et al.   CANCER BIOLOGY & THERAPY

Microaerobic conditions enhance type III secretion and adherence of enterohaemorrhagic Escherichia coli to polarized human intestinal epithelial cells

(2010) Stephanie Schüller et al.   ENVIRONMENTAL MICROBIOLOGY

Towards organ printing: engineering an intra-organ branched vascular tree

(2010) Richard P Visconti et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Genetics and Environmental Interactions Shape the Intestinal Microbiome to Promote Inflammatory Bowel Disease Versus Mucosal Homeostasis

(2010) R. Balfour Sartor   GASTROENTEROLOGY

Translocation of Crohn's disease Escherichia coli across M-cells: contrasting effects of soluble plant fibres and emulsifiers

(2010) C. L. Roberts et al.   GUT

A Dynamic in vitro BBB Model for the Study of Immune Cell Trafficking into the Central Nervous System

(2010) Luca Cucullo et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Microscale 3-D hydrogel scaffold for biomimetic gastrointestinal (GI) tract model

(2010) Jong Hwan Sung et al.   LAB ON A CHIP

Analysis of Interactions of Salmonella Type Three Secretion Mutants with 3-D Intestinal Epithelial Cells

(2010) Andrea L. Radtke et al.   PLoS One

Scaffold-free vascular tissue engineering using bioprinting

(2009) Cyrille Norotte et al.   BIOMATERIALS

Thermosensitive injectable hyaluronic acid hydrogel for adipose tissue engineering

(2009) Huaping Tan et al.   BIOMATERIALS

Towards the human intestinal microbiota phylogenetic core

(2009) Julien Tap et al.   ENVIRONMENTAL MICROBIOLOGY

Co-culture of epithelial cells and bacteria for investigating host–pathogen interactions

(2009) Jeongyun Kim et al.   LAB ON A CHIP

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Laser Printing of Skin Cells and Human Stem Cells

(2009) Lothar Koch et al.   TISSUE ENGINEERING PART C-METHODS

Theex vivoresponse of human intestinal mucosa to enteropathogenicEscherichia coliinfection

(2008) Stephanie Schüller et al.   CELLULAR MICROBIOLOGY

Enhanced Microscopic Definition of Campylobacter jejuni 81-176 Adherence to, Invasion of, Translocation across, and Exocytosis from Polarized Human Intestinal Caco-2 Cells

(2008) L. Hu et al.   INFECTION AND IMMUNITY

Lactobacillus rhamnosus Strain GG Prevents Enterohemorrhagic Escherichia coli O157:H7-Induced Changes in Epithelial Barrier Function

(2008) K. C. Johnson-Henry et al.   INFECTION AND IMMUNITY