Tolerogenic dendritic cells

Classical dendritic cells are required for dietary antigen–mediated induction of peripheral Treg cells and tolerance

(2016) Daria Esterházy et al.   NATURE IMMUNOLOGY

Tolerogenic nanoparticles inhibit T cell–mediated autoimmunity through SOCS2

(2016) Ada Yeste et al.   Science Signaling

Regulation of the T Cell Response by CD39

(2016) Maisa C. Takenaka et al.   TRENDS IN IMMUNOLOGY

Achieving Tolerance with Perforin-Secreting Dendritic Cells

(2016) Maisa C. Takenaka et al.   TRENDS IN MOLECULAR MEDICINE

Tolerogenic nanoparticles inhibit T cell–mediated autoimmunity through SOCS2

(2016) Ada Yeste et al.   Science Signaling

Melatonin Contributes to the Seasonality of Multiple Sclerosis Relapses

(2015) Mauricio F. Farez et al.   CELL

Perforin-Positive Dendritic Cells Exhibit an Immuno-regulatory Role in Metabolic Syndrome and Autoimmunity

(2015) Yael Zlotnikov-Klionsky et al.   IMMUNITY

DEC205+Dendritic Cell–Targeted Tolerogenic Vaccination Promotes Immune Tolerance in Experimental Autoimmune Arthritis

(2015) Rachel Spiering et al.   JOURNAL OF IMMUNOLOGY

Norepinephrine Controls Effector T Cell Differentiation through β2-Adrenergic Receptor–Mediated Inhibition of NF-κB and AP-1 in Dendritic Cells

(2015) Maisa Carla Takenaka et al.   JOURNAL OF IMMUNOLOGY

Intestinal CD103+CD11b− dendritic cells restrain colitis via IFN-γ-induced anti-inflammatory response in epithelial cells

(2015) A R B M Muzaki et al.   Mucosal Immunology

Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α

(2015) Ivan D Mascanfroni et al.   NATURE MEDICINE

Role and therapeutic value of dendritic cells in central nervous system autoimmunity

(2014) F J Quintana et al.   CELL DEATH AND DIFFERENTIATION

Differential Production of IL-23 and IL-12 by Myeloid-Derived Dendritic Cells in Response to TLR Agonists

(2014) R. E. Roses et al.   JOURNAL OF IMMUNOLOGY

Aryl Hydrocarbon Receptor and Kynurenine: Recent Advances in Autoimmune Disease Research

(2014) Nam Trung Nguyen et al.   Frontiers in Immunology

Immunological Relevance of the Coevolution of IDO1 and AHR

(2014) Merja Jaronen et al.   Frontiers in Immunology

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

(2013) Teresa Zelante et al.   IMMUNITY

Aryl hydrocarbon receptor signaling regulates NF-κB RelB activation during dendritic-cell differentiation

(2013) Christoph F A Vogel et al.   IMMUNOLOGY AND CELL BIOLOGY

Retinoic acid controls the homeostasis of pre-cDC–derived splenic and intestinal dendritic cells

(2013) Christopher A. Klebanoff et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Targeting of Autoantigens to DEC205+ Dendritic Cells In Vivo Suppresses Experimental Allergic Encephalomyelitis in Mice

(2013) S. Ring et al.   JOURNAL OF IMMUNOLOGY

 2-Adrenoreceptor Agonist Inhibits Antigen Cross-Presentation by Dendritic Cells

(2013) J. Herve et al.   JOURNAL OF IMMUNOLOGY

IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39

(2013) Ivan D Mascanfroni et al.   NATURE IMMUNOLOGY

Deletion of cognate CD8 T cells by immature dendritic cells: a novel role for perforin, granzyme A, TREM-1, and TLR7

(2012) L. Zangi et al.   BLOOD

Dendritic Cells Ameliorate Autoimmunity in the CNS by Controlling the Homeostasis of PD-1 Receptor+ Regulatory T Cells

(2012) Nir Yogev et al.   IMMUNITY

Krüppel-like factor 4 (KLF4) promotes the survival of natural killer cells and maintains the number of conventional dendritic cells in the spleen

(2012) Chun Shik Park et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Compensatory dendritic cell development mediated by BATF–IRF interactions

(2012) Roxane Tussiwand et al.   NATURE

Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses

(2012) Hideo Negishi et al.   NATURE IMMUNOLOGY

Nanoparticle-mediated codelivery of myelin antigen and a tolerogenic small molecule suppresses experimental autoimmune encephalomyelitis

(2012) A. Yeste et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Resolution Genome-wide Mapping of AHR and ARNT Binding Sites by ChIP-Seq

(2012) Raymond Lo et al.   TOXICOLOGICAL SCIENCES

Plasmacytoid Dendritic Cells: Recent Progress and Open Questions

(2011) Boris Reizis et al.   Annual Review of Immunology

Oral tolerance

(2011) Howard L. Weiner et al.   IMMUNOLOGICAL REVIEWS

In Vivo Induction of Tr1 Cells via Mucosal Dendritic Cells and AHR Signaling

(2011) Henry Yim Wu et al.   PLoS One

Dietary Ligands of the Aryl Hydrocarbon Receptor Induce Anti-Inflammatory and Immunoregulatory Effects on Murine Dendritic Cells

(2011) Jenna M. Benson et al.   TOXICOLOGICAL SCIENCES

Intestinal CD103+ dendritic cells: master regulators of tolerance?

(2011) Charlotte L. Scott et al.   TRENDS IN IMMUNOLOGY

Mammalian Per-Arnt-Sim Proteins in Environmental Adaptation

(2010) Brian E. McIntosh et al.   Annual Review of Physiology

Endogenous toll-like receptor ligands and their biological significance

(2010) Li Yu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Dendritic Cell (DC)-Specific Targeting Reveals Stat3 as a Negative Regulator of DC Function

(2010) Jessica A. Melillo et al.   JOURNAL OF IMMUNOLOGY

An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

(2010) J. D. Mezrich et al.   JOURNAL OF IMMUNOLOGY

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

(2010) Lionel Apetoh et al.   NATURE IMMUNOLOGY

Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell–like and Foxp3+ regulatory T cells

(2010) Roopali Gandhi et al.   NATURE IMMUNOLOGY

Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism

(2010) N. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Promoting tolerance to proteolipid protein-induced experimental autoimmune encephalomyelitis through targeting dendritic cells

(2010) J. N. H. Stern et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis

(2010) F. J. Quintana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retinoic Acid Can Directly Promote TGF-β-Mediated Foxp3+ Treg Cell Conversion of Naive T Cells

(2009) Daniel Mucida et al.   IMMUNITY

Origin of the Lamina Propria Dendritic Cell Network

(2009) Milena Bogunovic et al.   IMMUNITY

Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity

(2009) Caspar Ohnmacht et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Evidence for Ligand-Mediated Selective Modulation of Aryl Hydrocarbon Receptor Activity

(2009) I. A. Murray et al.   MOLECULAR PHARMACOLOGY

A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-κB family

(2008) Christoph F.A. Vogel et al.   BIOCHEMICAL PHARMACOLOGY

The significance of the nongenomic pathway in mediating inflammatory signaling of the dioxin-activated Ah receptor to cause toxic effects

(2008) Fumio Matsumura   BIOCHEMICAL PHARMACOLOGY

Activation of the aryl hydrocarbon receptor promotes allograft-specific tolerance through direct and dendritic cell-mediated effects on regulatory T cells

(2008) E. Hauben et al.   BLOOD

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

(2008) Francisco J. Quintana et al.   NATURE

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

(2008) K. Hildner et al.   SCIENCE

Regulatory T Cells: Mechanisms of Differentiation and Function

(2007) Steven Z. Josefowicz et al.   Annual Review of Immunology

The Search for Endogenous Activators of the Aryl Hydrocarbon Receptor

(2007) Linh P. Nguyen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Ligand-dependent interactions of the Ah receptor with coactivators in a mammalian two-hybrid assay

(2007) Shu Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY