Aging Gut Microbiota at the Cross-Road between Nutrition, Physical Frailty, and Sarcopenia: Is There a Gut–Muscle Axis?

Does nutrition play a role in the prevention and management of sarcopenia?

(2018) S.M. Robinson et al.   CLINICAL NUTRITION

The microbiome of professional athletes differs from that of more sedentary subjects in composition and particularly at the functional metabolic level

(2017) Wiley Barton et al.   GUT

Feeding the microbiota: transducer of nutrient signals for the host

(2017) Fergus Shanahan et al.   GUT

Faecalibacterium prausnitzii: from microbiology to diagnostics and prognostics

(2017) Mireia Lopez-Siles et al.   ISME Journal

Faecalibacterium prausnitzii treatment improves hepatic health and reduces adipose tissue inflammation in high-fat fed mice

(2017) Eveliina Munukka et al.   ISME Journal

Adherence to a Mediterranean Diet Influences the Fecal Metabolic Profile of Microbial-Derived Phenolics in a Spanish Cohort of Middle-Age and Older People

(2017) Isabel Gutiérrez-Díaz et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A gut reaction: the combined influence of exercise and diet on gastrointestinal microbiota in rats

(2017) R.B. Batacan et al.   JOURNAL OF APPLIED MICROBIOLOGY

Alterations to the Gut Microbiome Impair Bone Strength and Tissue Material Properties

(2017) Jason D Guss et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The Gut Metagenome Changes in Parallel to Waist Circumference, Brain Iron Deposition, and Cognitive Function

(2017) Gerard Blasco et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Muscle Ultrasound and Sarcopenia in Older Individuals: A Clinical Perspective

(2017) Andrea Ticinesi et al.   Journal of the American Medical Directors Association

Betaine promotes cell differentiation of human osteoblasts in primary culture

(2017) Isabella Villa et al.   Journal of Translational Medicine

Prevalence and Clinical Correlates of Sarcopenia, Identified According to the EWGSOP Definition and Diagnostic Algorithm, in Hospitalized Older People: The GLISTEN Study

(2017) Lara Bianchi et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Biological Aging and the Human Gut Microbiota

(2017) Vincent J Maffei et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Nutrition and physical activity in the prevention and treatment of sarcopenia: systematic review

(2017) C. Beaudart et al.   OSTEOPOROSIS INTERNATIONAL

Indoles from commensal bacteria extend healthspan

(2017) Robert Sonowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Association between Cardiorespiratory Fitness and Gut Microbiota Composition in Premenopausal Women

(2017) Yifan Yang et al.   Nutrients

Spirulina Protects against Hepatic Inflammation in Aging: An Effect Related to the Modulation of the Gut Microbiota?

(2017) Audrey Neyrinck et al.   Nutrients

Exercise and Protein Intake: A Synergistic Approach against Sarcopenia

(2017) Anna Maria Martone et al.   Biomed Research International

Moderate-Intensity Exercise Affects Gut Microbiome Composition and Influences Cardiac Function in Myocardial Infarction Mice

(2017) Zuheng Liu et al.   Frontiers in Microbiology

The incidence of sarcopenia among hospitalized older patients: results from the Glisten study

(2017) Anna Maria Martone et al.   Journal of Cachexia Sarcopenia and Muscle

The Crosstalk between the Gut Microbiota and Mitochondria during Exercise

(2017) Allison Clark et al.   Frontiers in Physiology

Community characteristics of the gut microbiomes of competitive cyclists

(2017) Lauren M. Petersen et al.   Microbiome

Maternal inheritance of bifidobacterial communities and bifidophages in infants through vertical transmission

(2017) Sabrina Duranti et al.   Microbiome

Next-generation probiotics: the spectrum from probiotics to live biotherapeutics

(2017) Paul W. O’Toole et al.   Nature Microbiology

Moderate Exercise Has Limited but Distinguishable Effects on the Mouse Microbiome

(2017) Emily V. Lamoureux et al.   mSystems

Differences in gut microbiota profile between women with active lifestyle and sedentary women

(2017) Carlo Bressa et al.   PLoS One

Health Outcomes of Sarcopenia: A Systematic Review and Meta-Analysis

(2017) Charlotte Beaudart et al.   PLoS One

Unraveling the gut microbiome of the long-lived naked mole-rat

(2017) Tewodros Debebe et al.   Scientific Reports

Gut microbiota composition is associated with polypharmacy in elderly hospitalized patients

(2017) Andrea Ticinesi et al.   Scientific Reports

High-intensity exercise training increases the diversity and metabolic capacity of the mouse distal gut microbiota during diet-induced obesity

(2016) Emmanuel Denou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Central Nervous System and the Gut Microbiome

(2016) Gil Sharon et al.   CELL

Gut Microbiota and Extreme Longevity

(2016) Elena Biagi et al.   CURRENT BIOLOGY

The human gut microbiome in health: establishment and resilience of microbiota over a lifetime

(2016) Kacy Greenhalgh et al.   ENVIRONMENTAL MICROBIOLOGY

Effect of a Prebiotic Formulation on Frailty Syndrome: A Randomized, Double-Blind Clinical Trial

(2016) Cristina Buigues et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of Gut Microbiota and Short Chain Fatty Acids in Modulating Energy Harvest and Fat Partitioning in Youth

(2016) Martina Goffredo et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The human gut microbiota and its interactive connections to diet

(2016) C. Milani et al.   JOURNAL OF HUMAN NUTRITION AND DIETETICS

Age-related changes in energy intake and weight in community-dwelling middle-aged and elderly Japanese

(2016) Rei Otsuka et al.   Journal of Nutrition Health & Aging

Comparison of Diet versus Exercise on Metabolic Function and Gut Microbiota in Obese Rats

(2016) REBECCA J. WELLY et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Acetate mediates a microbiome–brain–β-cell axis to promote metabolic syndrome

(2016) Rachel J. Perry et al.   NATURE

Diet–microbiota interactions as moderators of human metabolism

(2016) Justin L. Sonnenburg et al.   NATURE

Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents

(2016) Dongryeol Ryu et al.   NATURE MEDICINE

Signals from the gut microbiota to distant organs in physiology and disease

(2016) Bjoern O Schroeder et al.   NATURE MEDICINE

The Effect of Diet and Exercise on Intestinal Integrity and Microbial Diversity in Mice

(2016) Sara C. Campbell et al.   PLoS One

Gut microbiota induce IGF-1 and promote bone formation and growth

(2016) Jing Yan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

(2016) Alexandra Zhernakova et al.   SCIENCE

Gut bacteria that prevent growth impairments transmitted by microbiota from malnourished children

(2016) L. V. Blanton et al.   SCIENCE

Altered intestinal microbiota–host mitochondria crosstalk in new onset Crohn’s disease

(2016) Walid Mottawea et al.   Nature Communications

Nutrition and Inflammation in Older Individuals: Focus on Vitamin D, n-3 Polyunsaturated Fatty Acids and Whey Proteins

(2016) Andrea Ticinesi et al.   Nutrients

Anorexia of Aging: Risk Factors, Consequences, and Potential Treatments

(2016) Francesco Landi et al.   Nutrients

Beneficial bacteria inhibit cachexia

(2016) Bernard J. Varian et al.   Oncotarget

Signatures of early frailty in the gut microbiota

(2016) Matthew A. Jackson et al.   Genome Medicine

Gut Bifidobacteria Populations in Human Health and Aging

(2016) Silvia Arboleya et al.   Frontiers in Microbiology

The impact of ageing, physical activity, and pre-frailty on skeletal muscle phenotype, mitochondrial content, and intramyocellular lipids in men

(2016) Félix St-Jean-Pelletier et al.   Journal of Cachexia Sarcopenia and Muscle

Gut Microbiota Modification: Another Piece in the Puzzle of the Benefits of Physical Exercise in Health?

(2016) Begoña Cerdá et al.   Frontiers in Physiology

Interpreting Prevotella and Bacteroides as biomarkers of diet and lifestyle

(2016) Anastassia Gorvitovskaia et al.   Microbiome

Cardiorespiratory fitness as a predictor of intestinal microbial diversity and distinct metagenomic functions

(2016) Mehrbod Estaki et al.   Microbiome

Functional metagenomic profiling of intestinal microbiome in extreme ageing

(2016) Simone Rampelli et al.   Aging-US

Gut microbiota composition and Clostridium difficile infection in hospitalized elderly individuals: a metagenomic study

(2016) Christian Milani et al.   Scientific Reports

Elderly patients have an altered gut-brain axis regardless of the presence of cirrhosis

(2016) Jasmohan S. Bajaj et al.   Scientific Reports

The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging

(2015) Michael E. Walsh et al.   AGING CELL

Muscle Quality and Myosteatosis: Novel Associations With Mortality Risk

(2015) Ilse Reinders et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Sarcopenia and malnutrition in acutely ill hospitalized elderly: Prevalence and outcomes

(2015) Anna Paola Cerri et al.   CLINICAL NUTRITION

Influence of high-fat diet on gut microbiota

(2015) E. Angela Murphy et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

High-level adherence to a Mediterranean diet beneficially impacts the gut microbiota and associated metabolome

(2015) Francesca De Filippis et al.   GUT

The gut microbiota and host health: a new clinical frontier

(2015) Julian R Marchesi et al.   GUT

Composition and temporal stability of the gut microbiota in older persons

(2015) Ian B Jeffery et al.   ISME Journal

Instruments to Assess Sarcopenia and Physical Frailty in Older People Living in a Community (Care) Setting: Similarities and Discrepancies

(2015) Donja M. Mijnarends et al.   Journal of the American Medical Directors Association

Intramuscular Fat Infiltration Contributes to Impaired Muscle Function in COPD

(2015) PRISCILA GAMES ROBLES et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

The aromatic amino acid tryptophan stimulates skeletal muscle IGF1/p70s6k/mTor signaling in vivo and the expression of myogenic genes in vitro

(2015) Amy Dukes et al.   NUTRITION

Changes in Gut and Plasma Microbiome following Exercise Challenge in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

(2015) Sanjay K. Shukla et al.   PLoS One

Multimorbidity in elderly hospitalised patients and risk ofClostridium difficileinfection: a retrospective study with the Cumulative Illness Rating Scale (CIRS)

(2015) Andrea Ticinesi et al.   BMJ Open

Biomarkers for physical frailty and sarcopenia: state of the science and future developments

(2015) Riccardo Calvani et al.   Journal of Cachexia Sarcopenia and Muscle

Exercise Is More Effective at Altering Gut Microbial Composition and Producing Stable Changes in Lean Mass in Juvenile versus Adult Male F344 Rats

(2015) Agnieszka Mika et al.   PLoS One

Protection against the Metabolic Syndrome by Guar Gum-Derived Short-Chain Fatty Acids Depends on Peroxisome Proliferator-Activated Receptor γ and Glucagon-Like Peptide-1

(2015) Gijs den Besten et al.   PLoS One

Identification and treatment of older persons with sarcopenia

(2014) Fulvio Lauretani et al.   Aging Male

Protein intake and exercise for optimal muscle function with aging: Recommendations from the ESPEN Expert Group

(2014) Nicolaas E.P. Deutz et al.   CLINICAL NUTRITION

The Role of Malnutrition in Older Persons with Mobility Limitations

(2014) T. Cederholm et al.   CURRENT PHARMACEUTICAL DESIGN

Exercise and associated dietary extremes impact on gut microbial diversity

(2014) Siobhan F Clarke et al.   GUT

Correction: Through Ageing, and Beyond: Gut Microbiota and Inflammatory Status in Seniors and Centenarians

(2014) Elena Biagi et al.   PLoS One

Exercise Prevents Weight Gain and Alters the Gut Microbiota in a Mouse Model of High Fat Diet-Induced Obesity

(2014) Christian C. Evans et al.   PLoS One

Prevalence, incidence, and clinical impact of sarcopenia: facts, numbers, and epidemiology-update 2014

(2014) John E. Morley et al.   Journal of Cachexia Sarcopenia and Muscle

Age-related and disease-related muscle loss: the effect of diabetes, obesity, and other diseases

(2014) Rita Rastogi Kalyani et al.   Lancet Diabetes & Endocrinology

The SCFA Receptor GPR43 and Energy Metabolism

(2014) Ikuo Kimura et al.   Frontiers in Endocrinology

Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids

(2013) Gijs den Besten et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Exercise as a remedy for sarcopenia

(2013) Francesco Landi et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Mitochondrial dysfunction and sarcopenia of aging: From signaling pathways to clinical trials

(2013) Emanuele Marzetti et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

(2013) Gijs den Besten et al.   JOURNAL OF LIPID RESEARCH

Prevalence and Clinical Correlates of Sarcopenia in Community-Dwelling Older People: Application of the EWGSOP Definition and Diagnostic Algorithm

(2013) S. Volpato et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Frailty in elderly people

(2013) Andrew Clegg et al.   LANCET

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Assessing the Fecal Microbiota: An Optimized Ion Torrent 16S rRNA Gene-Based Analysis Protocol

(2013) Christian Milani et al.   PLoS One

IGF-1, the Cross Road of the Nutritional, Inflammatory and Hormonal Pathways to Frailty

(2013) Marcello Maggio et al.   Nutrients

Oxygen Consumption and Usage During Physical Exercise: The Balance Between Oxidative Stress and ROS-Dependent Adaptive Signaling

(2012) Zsolt Radak et al.   ANTIOXIDANTS & REDOX SIGNALING

Dietary (Poly)phenolics in Human Health: Structures, Bioavailability, and Evidence of Protective Effects Against Chronic Diseases

(2012) Daniele Del Rio et al.   ANTIOXIDANTS & REDOX SIGNALING

Bacteria as vitamin suppliers to their host: a gut microbiota perspective

(2012) Jean Guy LeBlanc et al.   CURRENT OPINION IN BIOTECHNOLOGY

Butyrate

(2012) Alda J. Leonel et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Gut microbiota composition correlates with diet and health in the elderly

(2012) Marcus J. Claesson et al.   NATURE

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

Human gut microbiome viewed across age and geography

(2012) Tanya Yatsunenko et al.   NATURE

The human microbiome: at the interface of health and disease

(2012) Ilseung Cho et al.   NATURE REVIEWS GENETICS

Role and potential mechanisms of anabolic resistance in sarcopenia

(2012) Prashanth H. Haran et al.   Journal of Cachexia Sarcopenia and Muscle

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People

(2010) A. J. Cruz-Jentoft et al.   AGE AND AGEING

A double-blind, placebo-controlled, cross-over study to establish the bifidogenic effect of a very-long-chain inulin extracted from globe artichoke ( Cynara scolymus) in healthy human subjects

(2010) Adele Costabile et al.   BRITISH JOURNAL OF NUTRITION

Dominant and diet-responsive groups of bacteria within the human colonic microbiota

(2010) Alan W Walker et al.   ISME Journal

Composition, variability, and temporal stability of the intestinal microbiota of the elderly

(2010) M. J. Claesson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

(2010) M. G. Dominguez-Bello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbial diversity in the human intestine and novel insights from metagenomics

(2009) Marco Ventura   Frontiers in Bioscience-Landmark

Microbes in Gastrointestinal Health and Disease

(2008) Andrew S. Neish   GASTROENTEROLOGY

Exercise, oxidative stress and hormesis

(2007) Zsolt Radak et al.   AGEING RESEARCH REVIEWS