Tolerogenic nanoparticles inhibit T cell–mediated autoimmunity through SOCS2

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It's Time to Bring Dendritic Cell Therapy to Type 1 Diabetes

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PhIP-Seq characterization of autoantibodies from patients with multiple sclerosis, type 1 diabetes and rheumatoid arthritis

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Dendritic Cell-Dependent In Vivo Generation of Autoregulatory T Cells by Antidiabetogenic MHC Class II

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IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39

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(2013) Åke Lernmark et al.   Nature Reviews Endocrinology

Plasmid-Encoded Proinsulin Preserves C-Peptide While Specifically Reducing Proinsulin-Specific CD8+ T Cells in Type 1 Diabetes

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Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis

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SOCS2-Induced Proteasome-Dependent TRAF6 Degradation: A Common Anti-Inflammatory Pathway for Control of Innate Immune Responses

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Nanoparticle-mediated codelivery of myelin antigen and a tolerogenic small molecule suppresses experimental autoimmune encephalomyelitis

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Expansion of Th17 Cells and Functional Defects in T Regulatory Cells Are Key Features of the Pancreatic Lymph Nodes in Patients With Type 1 Diabetes

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Antigen-specific prevention of type 1 diabetes in NOD mice is ameliorated by OX40 agonist treatment

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Suppressor of Cytokine Signaling 2 Is a Feedback Inhibitor of TLR-Induced Activation in Human Monocyte-Derived Dendritic Cells

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Development of Memory-Like Autoregulatory CD8+ T Cells Is CD4+ T Cell Dependent

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IL-17 Silencing Does Not Protect Nonobese Diabetic Mice from Autoimmune Diabetes

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Dietary Ligands of the Aryl Hydrocarbon Receptor Induce Anti-Inflammatory and Immunoregulatory Effects on Murine Dendritic Cells

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T cells enhance gold nanoparticle delivery to tumors in vivo

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Subcutaneous insulin B:9-23/IFA immunisation induces Tregs that control late-stage prediabetes in NOD mice through IL-10 and IFNγ

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Suppressor of cytokine signaling 1 (SOCS1) limits NFκB signaling by decreasing p65 stability within the cell nucleus

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Reversal of Autoimmunity by Boosting Memory-like Autoregulatory T Cells

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Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor–specified peripheral niche constraints

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IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells

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An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

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The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

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Chromogranin A is an autoantigen in type 1 diabetes

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Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism

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An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis

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How Punctual Ablation of Regulatory T Cells Unleashes an Autoimmune Lesion within the Pancreatic Islets

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Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice

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T-bet-Deficient NOD Mice Are Protected from Diabetes Due to Defects in Both T Cell and Innate Immune System Function

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SOCS2 Influences LPS Induced Human Monocyte-Derived Dendritic Cell Maturation

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Activation of the aryl hydrocarbon receptor promotes allograft-specific tolerance through direct and dendritic cell-mediated effects on regulatory T cells

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Analysis of islet inflammation in human type 1 diabetes

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Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

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Regulatory T Cells: Mechanisms of Differentiation and Function

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