Lactate Exposure Promotes Immunosuppressive Phenotypes in Innate Immune Cells
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Lactate Exposure Promotes Immunosuppressive Phenotypes in Innate Immune Cells
Authors
Keywords
-
Journal
Cellular and Molecular Bioengineering
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-09-22
DOI
10.1007/s12195-020-00652-x
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Intratumoral expression of IL-7 and IL-12 using an oncolytic virus increases systemic sensitivity to immune checkpoint blockade
- (2020) Shinsuke Nakao et al. Science Translational Medicine
- Lactate secreted by cervical cancer cells modulates macrophage phenotype
- (2019) Simone Cardozo Stone et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Efficiency of CAR-T Therapy for Treatment of Solid Tumor in Clinical Trials: A Meta-Analysis
- (2019) Bin Hou et al. DISEASE MARKERS
- Mechanistic basis of L-lactate transport in the SLC16 solute carrier family
- (2019) Patrick D. Bosshart et al. Nature Communications
- Significantly increased anti-tumor activity of carcinoembryonic antigen-specific chimeric antigen receptor T cells in combination with recombinant human IL-12
- (2019) Xiaowei Chi et al. Cancer Medicine
- Expression of CD38 on Macrophages Predicts Improved Prognosis in Hepatocellular Carcinoma
- (2019) Jian Hang Lam et al. Frontiers in Immunology
- Single injection of IL-12 coacervate as an effective therapy against B16-F10 melanoma in mice
- (2019) Mintai P. Hwang et al. JOURNAL OF CONTROLLED RELEASE
- Latent, Immunosuppressive Nature of Poly(lactic-co-glycolic acid) Microparticles
- (2018) Riley P. Allen et al. ACS Biomaterials-Science & Engineering
- CD38 Is Robustly Induced in Human Macrophages and Monocytes in Inflammatory Conditions
- (2018) Stephanie A. Amici et al. Frontiers in Immunology
- Latent, Immunosuppressive Nature of Poly(lactic-co-glycolic acid) Microparticles
- (2018) Riley P. Allen et al. ACS Biomaterials Science & Engineering
- Regulation of iNOS on Immune Cells and Its Role in Diseases
- (2018) Qingjie Xue et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- CD38: A Target for Immunotherapeutic Approaches in Multiple Myeloma
- (2018) Fabio Morandi et al. Frontiers in Immunology
- Gpr132 sensing of lactate mediates tumor–macrophage interplay to promote breast cancer metastasis
- (2017) Peiwen Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reprogramming of Tumor-Associated Macrophages with Anticancer Therapies: Radiotherapy versus Chemo- and Immunotherapies
- (2017) Géraldine Genard et al. Frontiers in Immunology
- A Breakthrough: Macrophage-Directed Cancer Immunotherapy
- (2016) C. D. Mills et al. CANCER RESEARCH
- LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells
- (2016) Almut Brand et al. Cell Metabolism
- In vitro generation of cytotoxic T lymphocyte response using dendritic cell immunotherapy in osteosarcoma
- (2016) Ye-Teng He et al. Oncology Letters
- Lactate Inhibits the Pro-Inflammatory Response and Metabolic Reprogramming in Murine Macrophages in a GPR81-Independent Manner
- (2016) Agustina Errea et al. PLoS One
- Macrophages and cancer: from mechanisms to therapeutic implications
- (2015) Renato Ostuni et al. TRENDS IN IMMUNOLOGY
- High expression of CD11c indicates favorable prognosis in patients with gastric cancer
- (2015) Yuan Wang WORLD JOURNAL OF GASTROENTEROLOGY
- Lactate Regulates Metabolic and Pro-inflammatory Circuits in Control of T Cell Migration and Effector Functions
- (2015) Robert Haas et al. PLOS BIOLOGY
- Reprogramming the tumor microenvironment: tumor-induced immunosuppressive factors paralyze T cells
- (2015) Annie A Wu et al. OncoImmunology
- Novel Markers to Delineate Murine M1 and M2 Macrophages
- (2015) Kyle A. Jablonski et al. PLoS One
- Metabolic Targeting of Lactate Efflux by Malignant Glioma Inhibits Invasiveness and Induces Necrosis: An In Vivo Study
- (2015) Chaim B Colen et al. NEOPLASIA
- Integrin-directed modulation of macrophage responses to biomaterials
- (2014) Toral D. Zaveri et al. BIOMATERIALS
- Tumor cells hijack macrophages via lactic acid
- (2014) Vincenzo Bronte IMMUNOLOGY AND CELL BIOLOGY
- The Monocarboxylate Transporter 4 Is Required for Glycolytic Reprogramming and Inflammatory Response in Macrophages
- (2014) Zheng Tan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dimethyl Sulfoxide Suppresses Mouse 4T1 Breast Cancer Growth by Modulating Tumor-Associated Macrophage Differentiation
- (2014) Rui Deng et al. Journal of Breast Cancer
- The chemotaxis of M1 and M2 macrophages is regulated by different chemokines
- (2014) Wenjuan Xuan et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The Warburg effect: molecular aspects and therapeutic possibilities
- (2014) Hanh Ngo et al. MOLECULAR BIOLOGY REPORTS
- Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
- (2014) Oscar R. Colegio et al. NATURE
- Disarmed by density
- (2014) Aikaterini Nasi et al. OncoImmunology
- Regulatory Multitasking of Tolerogenic Dendritic Cells – Lessons Taken from Vitamin D3-Treated Tolerogenic Dendritic Cells
- (2013) Tatjana Nikolic et al. Frontiers in Immunology
- Dendritic Cells: A Spot on Sialic Acid
- (2013) Hélio J. Crespo et al. Frontiers in Immunology
- Microparticle surface modifications targeting dendritic cells for non-activating applications
- (2012) Jamal S. Lewis et al. BIOMATERIALS
- The mouse dendritic cell marker CD11c is down-regulated upon cell activation through Toll-like receptor triggering
- (2012) Harpreet Singh-Jasuja et al. IMMUNOBIOLOGY
- Monocarboxylate transporters (MCTs) in gliomas: expression and exploitation as therapeutic targets
- (2012) Vera Miranda-Gonçalves et al. NEURO-ONCOLOGY
- Immunosuppression in the tumor microenvironment: Where are we standing?
- (2012) Viktor Umansky SEMINARS IN CANCER BIOLOGY
- Tumor lactic acidosis suppresses CTL function by inhibition of p38 and JNK/c-Jun activation
- (2011) Anna N. Mendler et al. INTERNATIONAL JOURNAL OF CANCER
- Brain Lactate Metabolism: The Discoveries and the Controversies
- (2011) Gerald A Dienel JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- In vivo modulation of dendritic cells by engineered materials: Towards new cancer vaccines
- (2011) Jaeyun Kim et al. Nano Today
- Interleukin 12 a Key Immunoregulatory Cytokine in Infection Applications
- (2010) Therwa Hamza et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Molecular signatures of maturing dendritic cells: implications for testing the quality of dendritic cell therapies
- (2010) Ping Jin et al. Journal of Translational Medicine
- AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7–10
- (2009) Matthew J. Ovens et al. BIOCHEMICAL JOURNAL
- Lipopolysaccharide-induced Maturation of Bone Marrow-derived Dendritic Cells Is Regulated by Notch Signaling through the Up-regulation of CXCR4
- (2009) Yao-Chun Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Alternatively activated macrophage-derived RELM-α is a negative regulator of type 2 inflammation in the lung
- (2009) Meera G. Nair et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Lactate Boosts TLR4 Signaling and NF- B Pathway-Mediated Gene Transcription in Macrophages via Monocarboxylate Transporters and MD-2 Up-Regulation
- (2009) D. J. Samuvel et al. JOURNAL OF IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More