Cellular Interactome of Mitochondrial Voltage-Dependent Anion Channels: Oligomerization and Channel (Mis)Regulation

VDAC—A Primal Perspective

(2021) Carmen A. Mannella   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

α-Synuclein emerges as a potent regulator of VDAC-facilitated calcium transport

(2021) William M. Rosencrans et al.   CELL CALCIUM

Voltage-Dependent Anion Selective Channel Isoforms in Yeast: Expression, Structure, and Functions

(2021) Maria Carmela Di Rosa et al.   Frontiers in Physiology

Structural basis of complex formation between mitochondrial anion channel VDAC1 and Hexokinase-II

(2021) Nandan Haloi et al.   Communications Biology

Porins as helpers in mitochondrial protein translocation

(2020) Alexander Grevel et al.   BIOLOGICAL CHEMISTRY

VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease

(2020) Jeonghan Kim et al.   SCIENCE

Nedd4 ubiquitylates VDAC2/3 to suppress erastin-induced ferroptosis in melanoma

(2020) Yongfei Yang et al.   Nature Communications

Arabidopsis Mitochondrial Voltage-Dependent Anion Channels Are Involved in Maintaining Reactive Oxygen Species Homeostasis, Oxidative and Salt Stress Tolerance in Yeast

(2020) Sibaji K. Sanyal et al.   Frontiers in Plant Science

Structure-based modeling of turnover of Bcl-2 family proteins bound to voltage-dependent anion channel 2 (VDAC2): Implications for the mechanisms of proapoptotic activation of Bak and Bax in vivo

(2020) Hanna V. Dudko et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

VDAC and its interacting partners in plant and animal systems: an overview

(2020) Poonam Kanwar et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

A short motif in the N-terminal region of α-synuclein is critical for both aggregation and function

(2020) Ciaran P. A. Doherty et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Targeting the Multiple Physiologic Roles of VDAC With Steroids and Hydrophobic Drugs

(2020) Tatiana K. Rostovtseva et al.   Frontiers in Physiology

Role of Mitochondria-Cytoskeleton Interactions in the Regulation of Mitochondrial Structure and Function in Cancer Stem Cells

(2020) Jungmin Kim et al.   Cells

Electrical control of the cell energy metabolism at the level of mitochondrial outer membrane

(2020) Victor V. Lemeshko   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Evolutionary selection of a 19-stranded mitochondrial β-barrel scaffold bears structural and functional significance

(2020) Shashank Ranjan Srivastava et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The signal distinguishing between targeting of outer membrane β-barrel protein to plastids and mitochondria in plants

(2019) Anna Klinger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Tubulin βII and βIII Isoforms as the Regulators of VDAC Channel Permeability in Health and Disease

(2019) Marju Puurand et al.   Cells

Probing Membrane Association of α-Synuclein Domains with VDAC Nanopore Reveals Unexpected Binding Pattern

(2019) Daniel Jacobs et al.   Scientific Reports

Porin Associates with Tom22 to Regulate the Mitochondrial Protein Gate Assembly

(2019) Haruka Sakaue et al.   MOLECULAR CELL

Dual Role of Mitochondrial Porin in Metabolite Transport across the Outer Membrane and Protein Transfer to the Inner Membrane

(2019) Lars Ellenrieder et al.   MOLECULAR CELL

Helix–strand interaction regulates stability and aggregation of the human mitochondrial membrane protein channel VDAC3

(2019) Ankit Gupta et al.   JOURNAL OF GENERAL PHYSIOLOGY

Ceramides bind VDAC2 to trigger mitochondrial apoptosis

(2019) Shashank Dadsena et al.   Nature Communications

Structural characterization of the human membrane protein VDAC2 in lipid bilayers by MAS NMR

(2019) Matthew T. Eddy et al.   JOURNAL OF BIOMOLECULAR NMR

A VDAC1-Derived N-Terminal Peptide Inhibits Mutant SOD1-VDAC1 Interactions and Toxicity in the SOD1 Model of ALS

(2019) Anna Shteinfer-Kuzmine et al.   Frontiers in Cellular Neuroscience

Microsporidia Interact with Host Cell Mitochondria via Voltage-Dependent Anion Channels Using Sporoplasm Surface Protein 1

(2019) Bing Han et al.   mBio

Multifaceted roles of porin in mitochondrial protein and lipid transport

(2019) Toshiya Endo et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Molecular mechanism of olesoxime-mediated neuroprotection through targeting α-synuclein interaction with mitochondrial VDAC

(2019) Amandine Rovini et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis

(2019) Mark F. van Delft et al.   Nature Chemical Biology

Cryo-EM structure of the mitochondrial protein-import channel TOM complex at near-atomic resolution

(2019) Kyle Tucker et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Gasotransmitter hydrogen sulfide signaling in neuronal health and disease

(2018) Bindu D. Paul et al.   BIOCHEMICAL PHARMACOLOGY

Mitochondrial Outer Membrane Channels: Emerging Diversity in Transport Processes

(2018) Thomas Becker et al.   BIOESSAYS

VDAC1 functions in Ca 2+ homeostasis and cell life and death in health and disease

(2018) Varda Shoshan-Barmatz et al.   CELL CALCIUM

Interactions of VDAC with Proteins Involved in Neurodegenerative Aggregation: An Opportunity for Advancement on Therapeutic Molecules

(2018) Andrea Magri et al.   CURRENT MEDICINAL CHEMISTRY

The complexity of mitochondrial outer membrane permeability and VDAC regulation by associated proteins

(2018) Aleksandr Klepinin et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Sequence diversity of tubulin isotypes in regulation of the mitochondrial voltage-dependent anion channel

(2018) Tatiana K. Rostovtseva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Structural Annotation of Membrane Protein Aggregation Loci using Peptide-Based Reverse Mapping

(2018) Muralikrishna Lella et al.   Journal of Physical Chemistry Letters

Ten Years of High Resolution Structural Research on the Voltage Dependent Anion Channel (VDAC)—Recent Developments and Future Directions

(2018) Kornelius Zeth et al.   Frontiers in Physiology

VDAC1 as Pharmacological Target in Cancer and Neurodegeneration: Focus on Its Role in Apoptosis

(2018) Andrea Magrì et al.   Frontiers in Chemistry

Porin proteins have critical functions in mitochondrial phospholipid metabolism in yeast

(2018) Non Miyata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VDAC2 interacts with PFKP to regulate glucose metabolism and phenotypic reprogramming of glioma stem cells

(2018) Kai Zhou et al.   Cell Death & Disease

Assessing the role of residue E73 and lipid headgroup charge in VDAC1 voltage gating

(2018) María Queralt-Martín et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Hydrophobic Mismatch Modulates Stability and Plasticity of Human Mitochondrial VDAC2

(2018) Shashank Ranjan Srivastava et al.   BIOPHYSICAL JOURNAL

Pharmacological modulation of mitochondrial ion channels

(2018) Luigi Leanza et al.   BRITISH JOURNAL OF PHARMACOLOGY

VDAC2 enables BAX to mediate apoptosis and limit tumor development

(2018) Hui San Chin et al.   Nature Communications

Regulation of Calcium Homeostasis by ER Redox: A Close-Up of the ER/Mitochondria Connection

(2017) Alexander L. Chernorudskiy et al.   JOURNAL OF MOLECULAR BIOLOGY

Voltage-Dependent Anion Channel 1 Interacts with Ribonucleoprotein Complexes To Enhance Infectious Bursal Disease Virus Polymerase Activity

(2017) Chunyan Han et al.   JOURNAL OF VIROLOGY

Protein–protein interaction networks as a new perspective to evaluate distinct functional roles of voltage-dependent anion channel isoforms

(2017) Marianna Caterino et al.   Molecular BioSystems

Crystal structural characterization reveals novel oligomeric interactions of human voltage-dependent anion channel 1

(2017) Toshiaki Hosaka et al.   PROTEIN SCIENCE

Mitochondrial VDAC1: A Key Gatekeeper as Potential Therapeutic Target

(2017) Amadou K. S. Camara et al.   Frontiers in Physiology

VDAC–Tubulin, an Anti-Warburg Pro-Oxidant Switch

(2017) Eduardo N. Maldonado   Frontiers in Oncology

The Mitochondrial Voltage-Dependent Anion Channel 1, Ca2+ Transport, Apoptosis, and Their Regulation

(2017) Varda Shoshan-Barmatz et al.   Frontiers in Oncology

Erastin-Like Anti-Warburg Agents Prevent Mitochondrial Depolarization Induced by Free Tubulin and Decrease Lactate Formation in Cancer Cells

(2017) David N. DeHart et al.   SLAS Discovery

The multiple assemblies of VDAC: from conformational heterogeneity to β-aggregation and amyloid formation

(2016) Alexandre Boulbrima et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Role of cysteines in mammalian VDAC isoforms' function

(2016) Vito De Pinto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

A computational study of ion current modulation in hVDAC3 induced by disulfide bonds

(2016) Carlo Guardiani et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

VDAC electronics: 3. VDAC-Creatine kinase-dependent generation of the outer membrane potential in respiring mitochondria

(2016) Victor V. Lemeshko   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Control of human VDAC-2 scaffold dynamics by interfacial tryptophans is position specific

(2016) Svetlana Rajkumar Maurya et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Current state of theoretical and experimental studies of the voltage-dependent anion channel (VDAC)

(2016) Sergei Yu. Noskov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The VDAC channel: Molecular basis for selectivity

(2016) Marco Colombini   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

VDAC2-specific cellular functions and the underlying structure

(2016) Shamim Naghdi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mitochondrial VDAC2 and cell homeostasis: highlighting hidden structural features and unique functionalities

(2016) Svetlana Rajkumar Maurya et al.   BIOLOGICAL REVIEWS

Bax assembly into rings and arcs in apoptotic mitochondria is linked to membrane pores

(2016) R. Salvador-Gallego et al.   EMBO JOURNAL

Bax assembles into large ring-like structures remodeling the mitochondrial outer membrane in apoptosis

(2016) L. Grosse et al.   EMBO JOURNAL

VDAC-2: Mitochondrial outer membrane regulator masquerading as a channel?

(2016) Svetlana Rajkumar Maurya et al.   FEBS Journal

Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction

(2016) Danya Ben-Hail et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of a novel β-barrel protein (AtOM47) from the mitochondrial outer membrane ofArabidopsis thaliana

(2016) Lu Li et al.   JOURNAL OF EXPERIMENTAL BOTANY

The MicroRNA-224 Inhibitor Prevents Neuronal Apoptosis via Targeting Spastic Paraplegia 7 After Cerebral Ischemia

(2016) Feng Fu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Molecular Plasticity of the Human Voltage-Dependent Anion Channel Embedded Into a Membrane

(2016) Lin Ge et al.   STRUCTURE

VDAC3 as a sensor of oxidative state of the intermembrane space of mitochondria: the putative role of cysteine residue modifications

(2016) Simona Reina et al.   Oncotarget

VDAC3 As a Potential Marker of Mitochondrial Status Is Involved in Cancer and Pathology

(2016) Simona Reina et al.   Frontiers in Oncology

MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals

(2015) Jia Yuan et al.   Autophagy

VDAC3 gating is activated by suppression of disulfide-bond formation between the N-terminal region and the bottom of the pore

(2015) Masateru Okazaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The mitochondrial voltage-dependent anion channel 1 in tumor cells

(2015) Varda Shoshan-Barmatz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Structural basis of intramitochondrial phosphatidic acid transport mediated by Ups1-Mdm35 complex

(2015) F. Yu et al.   EMBO REPORTS

Novel mitochondrial protein interactors of immunoglobulin light chains causing heart amyloidosis

(2015) Francesca Lavatelli et al.   FASEB JOURNAL

N-helix and Cysteines Inter-regulate Human Mitochondrial VDAC-2 Function and Biochemistry

(2015) Svetlana Rajkumar Maurya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Voltage-dependent Anion Channel 1 Mediates Amyloid β Toxicity and Represents a Potential Target for Alzheimer Disease Therapy

(2015) Angela Smilansky et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Association of Receptor of Activated Protein Kinase C 1(RACK1) with Infectious Bursal Disease Virus Viral Protein VP5 and Voltage-dependent Anion Channel 2 (VDAC2) Inhibits Apoptosis and Enhances Viral Replication

(2015) Wencheng Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α-Synuclein Shows High Affinity Interaction with Voltage-dependent Anion Channel, Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease

(2015) Tatiana K. Rostovtseva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction between RING1 (R1) and the Ubiquitin-like (UBL) Domains Is Critical for the Regulation of Parkin Activity

(2015) Su Jin Ham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tubulin Tail Sequences and Post-translational Modifications Regulate Closure of Mitochondrial Voltage-dependent Anion Channel (VDAC)

(2015) Kely L. Sheldon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitative expression proteomics and phosphoproteomics profile of brain from PINK1 knockout mice: insights into mechanisms of familial Parkinson's disease

(2015) Judy C. Triplett et al.   JOURNAL OF NEUROCHEMISTRY

Molecular Details of α-Synuclein Membrane Association Revealed by Neutrons and Photons

(2015) Zhiping Jiang et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Succination is Increased on Select Proteins in the Brainstem of the NADH dehydrogenase (ubiquinone) Fe-S protein 4 (Ndufs4) Knockout Mouse, a Model of Leigh Syndrome

(2015) Gerardo G. Piroli et al.   MOLECULAR & CELLULAR PROTEOMICS

The proteomic 2D-DIGE approach reveals the protein voltage-dependent anion channel 2 as a potential therapeutic target in epithelial thyroid tumours

(2015) Eugenia Mato et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Motifs of VDAC2 required for mitochondrial Bak import and tBid-induced apoptosis

(2015) Shamim Naghdi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aggregated α-synuclein and complex I deficiency: exploration of their relationship in differentiated neurons

(2015) A K Reeve et al.   Cell Death & Disease

VDAC electronics: 1. VDAC-hexo(gluco)kinase generator of the mitochondrial outer membrane potential

(2014) Victor V. Lemeshko   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Altered dopamine homeostasis differentially affects mitochondrial voltage-dependent anion channels turnover

(2014) Tiziana Alberio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

α-Synuclein amino terminus regulates mitochondrial membrane permeability

(2014) Jiamei Shen et al.   BRAIN RESEARCH

Metaxins 1 and 2, two proteins of the mitochondrial protein sorting and assembly machinery, are essential for Bak activation during TNF alpha triggered apoptosis

(2014) Pierre-François Cartron et al.   CELLULAR SIGNALLING

Weakly Stable Regions and Protein-Protein Interactions in Beta-Barrel Membrane Proteins

(2014) Hammad Naveed et al.   CURRENT PHARMACEUTICAL DESIGN

The role of tubulin in the mitochondrial metabolism and arrangement in muscle cells

(2014) Kersti Tepp et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

High Resolution Structure and Double Electron-Electron Resonance of the Zebrafish Voltage-dependent Anion Channel 2 Reveal an Oligomeric Population

(2014) Johann Schredelseker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondria-associated Endoplasmic Reticulum Membrane (MAM) Regulates Steroidogenic Activity via Steroidogenic Acute Regulatory Protein (StAR)-Voltage-dependent Anion Channel 2 (VDAC2) Interaction

(2014) Manoj Prasad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Live cell interactome of the human voltage dependent anion channel 3 (VDAC3) revealed in HeLa cells by affinity purification tag technique

(2014) Angela Messina et al.   Molecular BioSystems

Influence of Protein – Micelle Ratios and Cysteine Residues on the Kinetic Stability and Unfolding Rates of Human Mitochondrial VDAC-2

(2014) Svetlana Rajkumar Maurya et al.   PLoS One

Mcl-1 promotes lung cancer cell migration by directly interacting with VDAC to increase mitochondrial Ca2+ uptake and reactive oxygen species generation

(2014) H Huang et al.   Cell Death & Disease

Silencing VDAC1 Expression by siRNA Inhibits Cancer Cell Proliferation and Tumor Growth In Vivo

(2014) Tasleem Arif et al.   Molecular Therapy-Nucleic Acids

Voltage-dependent anion channel involved in the α-synuclein-induced dopaminergic neuron toxicity in rats

(2013) Lingling Lu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

ATP Transport through VDAC and the VDAC–Tubulin Complex Probed by Equilibrium and Nonequilibrium MD Simulations

(2013) Sergei Yu. Noskov et al.   BIOCHEMISTRY

Amyloid beta-induced glycogen synthase kinase 3β phosphorylated VDAC1 in Alzheimer's disease: Implications for synaptic dysfunction and neuronal damage

(2013) P. Hemachandra Reddy   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Potential Role of BNIP3 in Cardiac Remodeling, Myocardial Stiffness, and Endoplasmic Reticulum

(2013) Antoine H. Chaanine et al.   Circulation-Heart Failure

Endonuclease G mediates α-synuclein cytotoxicity during Parkinson's disease

(2013) Sabrina Büttner et al.   EMBO JOURNAL

Voltage-dependent Anion Channels Modulate Mitochondrial Metabolism in Cancer Cells

(2013) Eduardo N. Maldonado et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane Remodeling by α-Synuclein and Effects on Amyloid Formation

(2013) Zhiping Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The mitochondrial permeability transition pore regulates Parkinson's disease development in mutant α-synuclein transgenic mice

(2013) Lee J. Martin et al.   NEUROBIOLOGY OF AGING

Aberrant Protein S-Nitrosylation in Neurodegenerative Diseases

(2013) Tomohiro Nakamura et al.   NEURON

α-Synuclein and Mitochondria: Partners in Crime?

(2013) Ken Nakamura   Neurotherapeutics

Cytoskeleton and regulation of mitochondrial function: the role of beta-tubulin II

(2013) Andrey V. Kuznetsov et al.   Frontiers in Physiology

Redox regulation of mitochondrial function with emphasis on cysteine oxidation reactions

(2013) Ryan J. Mailloux et al.   Redox Biology

VDAC: old protein with new roles in diabetes

(2012) Koh Sasaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Voltage-Dependent Anion Channel-2 Interaction with Nitric Oxide Synthase Enhances Pulmonary Artery Endothelial Cell Nitric Oxide Production

(2012) Cristina M. Alvira et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

ANT-VDAC1 interaction is direct and depends on ANT isoform conformation in vitro

(2012) Maya Allouche et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Role of Lipids in VDAC Oligomerization

(2012) Viktoria Betaneli et al.   BIOPHYSICAL JOURNAL

Mitochondrial Ca2+ and apoptosis

(2012) Carlotta Giorgi et al.   CELL CALCIUM

VDAC3 regulates centriole assembly by targeting Mps1 to centrosomes

(2012) Shubhra Majumder et al.   CELL CYCLE

Disruption of the VDAC2–Bak interaction by Bcl-xS mediates efficient induction of apoptosis in melanoma cells

(2012) M Plötz et al.   CELL DEATH AND DIFFERENTIATION

Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease

(2012) M. Manczak et al.   HUMAN MOLECULAR GENETICS

Mediation of the Antiapoptotic Activity of Bcl-xL Protein upon Interaction with VDAC1 Protein

(2012) Nir Arbel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane Lipid Composition Regulates Tubulin Interaction with Mitochondrial Voltage-dependent Anion Channel

(2012) Tatiana K. Rostovtseva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Voltage-dependent Anion Channels (VDACs) Recruit Parkin to Defective Mitochondria to Promote Mitochondrial Autophagy

(2012) Yu Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adseverin: A novel cisplatin-resistant marker in the human bladder cancer cell line HT1376 identified by quantitative proteomic analysis

(2012) Noriyoshi Miura et al.   Molecular Oncology

β-Barrel Mobility Underlies Closure of the Voltage-Dependent Anion Channel

(2012) Ulrich Zachariae et al.   STRUCTURE

VDAC1: from structure to cancer therapy

(2012) Varda Shoshan-Barmatz et al.   Frontiers in Oncology

Regulation of mitochondrial function by voltage dependent anion channels in ethanol metabolism and the Warburg effect

(2011) John J. Lemasters et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Phylogenetic and coevolutionary analysis of the β-barrel protein family comprised of mitochondrial porin (VDAC) and Tom40

(2011) Denice C. Bay et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

VDAC, The early days

(2011) Marco Colombini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Solution NMR spectroscopic characterization of human VDAC-2 in detergent micelles and lipid bilayer nanodiscs

(2011) Tsyr-Yan Yu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

VDAC inhibition by tubulin and its physiological implications

(2011) Tatiana K. Rostovtseva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Biophysics of α-synuclein membrane interactions

(2011) Candace M. Pfefferkorn et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria

(2011) D De Stefani et al.   CELL DEATH AND DIFFERENTIATION

Structure-based Analysis of VDAC1 Protein

(2011) Shay Geula et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Carnitine Palmitoyltransferase 1a (CPT1a) Is Part of an Outer Membrane Fatty Acid Transfer Complex

(2011) Kwangwon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial Expression, Purification and Characterization of a Rice Voltage-Dependent, Anion-Selective Channel Isoform, OsVDAC4

(2011) Ashwini Godbole et al.   JOURNAL OF MEMBRANE BIOLOGY

Critical Role for Voltage-Dependent Anion Channel 2 in Infectious Bursal Disease Virus-Induced Apoptosis in Host Cells via Interaction with VP5

(2011) Z. Li et al.   JOURNAL OF VIROLOGY

MAP4 Mechanism that Stabilizes Mitochondrial Permeability Transition in Hypoxia: Microtubule Enhancement and DYNLT1 Interaction with VDAC1

(2011) Ya-dong Fang et al.   PLoS One

Mitochondrial proteome analysis reveals altered expression of voltage dependent anion channels in pancreatic β-cells exposed to high glucose

(2011) Meftun Ahmed et al.   Islets

Dominant-negative VDAC1 mutants reveal oligomeric VDAC1 to be the active unit in mitochondria-mediated apoptosis

(2010) Asaf Mader et al.   BIOCHEMICAL JOURNAL

Apoptosis is regulated by the VDAC1 N-terminal region and by VDAC oligomerization: release of cytochrome c, AIF and Smac/Diablo

(2010) Varda Shoshan-Barmatz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Free Tubulin Modulates Mitochondrial Membrane Potential in Cancer Cells

(2010) E. N. Maldonado et al.   CANCER RESEARCH

Crystal packing analysis of murine VDAC1 crystals in a lipidic environment reveals novel insights on oligomerization and orientation

(2010) Rachna Ujwal et al.   Channels

α-Synuclein induced membrane depolarization and loss of phosphorylation capacity of isolated rat brain mitochondria: Implications in Parkinson's disease

(2010) Kalpita Banerjee et al.   FEBS LETTERS

Inhibition of Bak Activation by VDAC2 Is Dependent on the Bak Transmembrane Anchor

(2010) Michael Lazarou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Transgenic Overexpression of α-Synuclein and Not Its Related Pathology Associates with Complex I Inhibition

(2010) Virginie Loeb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multifunctional roles of gelsolin in health and diseases

(2010) Guo Hua Li et al.   MEDICINAL RESEARCH REVIEWS

Oligomerization of the Mitochondrial Protein Voltage-Dependent Anion Channel Is Coupled to the Induction of Apoptosis

(2010) N. Keinan et al.   MOLECULAR AND CELLULAR BIOLOGY

VDAC, a multi-functional mitochondrial protein regulating cell life and death

(2010) Varda Shoshan-Barmatz et al.   MOLECULAR ASPECTS OF MEDICINE

Mitochondrial alpha-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo

(2010) Shankar J. Chinta et al.   NEUROSCIENCE LETTERS

The role of solution NMR in the structure determinations of VDAC-1 and other membrane proteins

(2009) Sebastian Hiller et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Apoptosis: it's BAK to VDAC

(2009) Gordon C. Shore   EMBO REPORTS

VDAC2 is required for truncated BID-induced mitochondrial apoptosis by recruiting BAK to the mitochondria

(2009) Soumya Sinha Roy et al.   EMBO REPORTS

The VDAC1 N-terminus is essential both for apoptosis and the protective effect of anti-apoptotic proteins

(2009) S. Abu-Hamad et al.   JOURNAL OF CELL SCIENCE

The VDAC2-BAK Rheostat Controls Thymocyte Survival

(2009) D. Ren et al.   Science Signaling

Steroidogenic Activity of StAR Requires Contact with Mitochondrial VDAC1 and Phosphate Carrier Protein

(2008) Mahuya Bose et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Import and Accumulation of α-Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease Brain

(2008) Latha Devi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Mitochondria Are Required for α-Synuclein Toxicity in Aging Yeast

(2008) Sabrina Büttner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Optical Reporters for the Conformation of  -Synuclein Reveal a Specific Interaction with Mitochondria

(2008) K. Nakamura et al.   JOURNAL OF NEUROSCIENCE

VDAC2 and aldolase A identified as membrane proteins of K562 cells with increased expression under iron deprivation

(2008) Karel Valis et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Tubulin binding blocks mitochondrial voltage-dependent anion channel and regulates respiration

(2008) T. K. Rostovtseva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the human voltage-dependent anion channel

(2008) M. Bayrhuber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating

(2008) R. Ujwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solution Structure of the Integral Human Membrane Protein VDAC-1 in Detergent Micelles

(2008) S. Hiller et al.   SCIENCE