Targeting the Multiple Physiologic Roles of VDAC With Steroids and Hydrophobic Drugs
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Title
Targeting the Multiple Physiologic Roles of VDAC With Steroids and Hydrophobic Drugs
Authors
Keywords
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Journal
Frontiers in Physiology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-05-07
DOI
10.3389/fphys.2020.00446
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Note: Only part of the references are listed.- The antiarrhythmic compound efsevin directly modulates voltage‐dependent anion channel 2 by binding to its inner wall and enhancing mitochondrial Ca 2+ uptake
- (2020) Fabiola Wilting et al. BRITISH JOURNAL OF PHARMACOLOGY
- A lower affinity to cytosolic proteins reveals VDAC3 isoform-specific role in mitochondrial biology
- (2020) María Queralt-Martín et al. JOURNAL OF GENERAL PHYSIOLOGY
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- (2019) D. Perini et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Olesoxime in neurodegenerative diseases: Scrutinising a promising drug candidate
- (2019) Jonasz Jeremiasz Weber et al. BIOCHEMICAL PHARMACOLOGY
- Multiple neurosteroid and cholesterol binding sites in voltage-dependent anion channel-1 determined by photo-affinity labeling
- (2019) Wayland W.L. Cheng et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Molecular mechanism of olesoxime-mediated neuroprotection through targeting α-synuclein interaction with mitochondrial VDAC
- (2019) Amandine Rovini et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis
- (2019) Mark F. van Delft et al. Nature Chemical Biology
- VDAC1 functions in Ca 2+ homeostasis and cell life and death in health and disease
- (2018) Varda Shoshan-Barmatz et al. CELL CALCIUM
- Interactions of VDAC with Proteins Involved in Neurodegenerative Aggregation: An Opportunity for Advancement on Therapeutic Molecules
- (2018) Andrea Magri et al. CURRENT MEDICINAL CHEMISTRY
- VDAC-Targeted Drugs Affecting Cytoprotection and Mitochondrial Physiology in Cerebrovascular and Cardiovascular Diseases
- (2018) Andonis Karachitos et al. CURRENT MEDICINAL CHEMISTRY
- Anti-Cancer Compounds Targeted to VDAC: Potential and Perspectives
- (2018) Simona Reina et al. CURRENT MEDICINAL CHEMISTRY
- Mitochondrial dysfunction in obesity
- (2018) Aline Haas de Mello et al. LIFE SCIENCES
- VDAC1, mitochondrial dysfunction, and Alzheimer's disease
- (2018) Varda Shoshan-Barmatz et al. PHARMACOLOGICAL RESEARCH
- α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease
- (2018) Marthe H. R. Ludtmann et al. Nature Communications
- Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles
- (2018) Massimo Bonora et al. Nature Reviews Cardiology
- New insights into the complex role of mitochondria in Parkinson’s disease
- (2018) Anne Grünewald et al. PROGRESS IN NEUROBIOLOGY
- Sulindac sulfone inhibits the mTORC1 pathway in colon cancer cells by directly targeting voltage-dependent anion channel 1 and 2
- (2018) Yuichi Aono et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Assessing the role of residue E73 and lipid headgroup charge in VDAC1 voltage gating
- (2018) María Queralt-Martín et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Pharmacological modulation of mitochondrial ion channels
- (2018) Luigi Leanza et al. BRITISH JOURNAL OF PHARMACOLOGY
- VDAC2 enables BAX to mediate apoptosis and limit tumor development
- (2018) Hui San Chin et al. Nature Communications
- Photoaffinity labeling with cholesterol analogues precisely maps a cholesterol-binding site in voltage-dependent anion channel-1
- (2017) Melissa M. Budelier et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Synucleinopathies: Twenty Years On
- (2017) Michel Goedert et al. Journal of Parkinsons Disease
- Mitochondrial VDAC1: A Key Gatekeeper as Potential Therapeutic Target
- (2017) Amadou K. S. Camara et al. Frontiers in Physiology
- Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis
- (2016) Sarah A. Head et al. ACS Chemical Biology
- Novel targets for mitochondrial medicine
- (2016) Wang Wang et al. Science Translational Medicine
- VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington’s disease
- (2016) Xing Guo et al. Nature Communications
- Conductance hysteresis in the voltage-dependent anion channel
- (2015) Shay M. Rappaport et al. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
- N-helix and Cysteines Inter-regulate Human Mitochondrial VDAC-2 Function and Biochemistry
- (2015) Svetlana Rajkumar Maurya et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- α-Synuclein Shows High Affinity Interaction with Voltage-dependent Anion Channel, Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease
- (2015) Tatiana K. Rostovtseva et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dynamic memory of a single voltage-gated potassium ion channel: A stochastic nonequilibrium thermodynamic analysis
- (2015) Kinshuk Banerjee JOURNAL OF CHEMICAL PHYSICS
- Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells
- (2015) Sarah A. Head et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial Ca2+ uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity
- (2015) Hirohito Shimizu et al. eLife
- VDAC electronics: 2. A new, anaerobic mechanism of generation of the membrane potentials in mitochondria
- (2014) Victor V. Lemeshko BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- VDAC electronics: 1. VDAC-hexo(gluco)kinase generator of the mitochondrial outer membrane potential
- (2014) Victor V. Lemeshko BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Protective role of olesoxime against wild-type α-synuclein-induced toxicity in human neuronally differentiated SHSY-5Y cells
- (2014) C Gouarné et al. BRITISH JOURNAL OF PHARMACOLOGY
- Sites and functional consequence of VDAC-alkylphenol anesthetic interactions
- (2014) Brian P. Weiser et al. FEBS LETTERS
- Acidification Asymmetrically Affects Voltage-dependent Anion Channel Implicating the Involvement of Salt Bridges
- (2014) Oscar Teijido et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Computational Investigation of Cholesterol Binding Sites on Mitochondrial VDAC
- (2014) Brian P. Weiser et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Origin of ion selectivity in Phaseolus coccineus mitochondrial VDAC
- (2014) Eva-Maria Krammer et al. MITOCHONDRION
- ATP/ADP ratio, the missed connection between mitochondria and the Warburg effect
- (2014) Eduardo N. Maldonado et al. MITOCHONDRION
- Charged Residues Distribution Modulates Selectivity of the Open State of Human Isoforms of the Voltage Dependent Anion-Selective Channel
- (2014) Giuseppe Federico Amodeo et al. PLoS One
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- A propofol binding site on mammalian GABAA receptors identified by photolabeling
- (2013) Grace M S Yip et al. Nature Chemical Biology
- Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells
- (2013) Jonathan J Hulce et al. NATURE METHODS
- Lipid Transport between the Endoplasmic Reticulum and Mitochondria
- (2013) V. V. Flis et al. Cold Spring Harbor Perspectives in Biology
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- VDAC isoforms in mammals
- (2011) Angela Messina et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Tubulin-blocked state of VDAC studied by polymer and ATP partitioning
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- VDAC, a multi-functional mitochondrial protein as a pharmacological target
- (2011) Varda Shoshan-Barmatz et al. MITOCHONDRION
- Olesoxime prevents microtubule-targeting drug neurotoxicity: Selective preservation of EB comets in differentiated neuronal cells
- (2010) Amandine Rovini et al. BIOCHEMICAL PHARMACOLOGY
- Approaches for targeting mitochondria in cancer therapy
- (2010) Gerard G.M. D'Souza et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Modulation of Plant Mitochondrial VDAC by Phytosterols
- (2010) Lamia Mlayeh et al. BIOPHYSICAL JOURNAL
- Free Tubulin Modulates Mitochondrial Membrane Potential in Cancer Cells
- (2010) E. N. Maldonado et al. CANCER RESEARCH
- Mitochondrial alpha-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo
- (2010) Shankar J. Chinta et al. NEUROSCIENCE LETTERS
- Amphiphile regulation of ion channel function by changes in the bilayer spring constant
- (2010) J. A. Lundbaek et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lipid-Dependent Effects of Halothane on Gramicidin Channel Kinetics: A New Role for Lipid Packing Stress
- (2009) Michael Weinrich et al. BIOCHEMISTRY
- The influence of the membrane on neurosteroid actions at GABAA receptors
- (2009) Gustav Akk et al. PSYCHONEUROENDOCRINOLOGY
- Interactions of sulindac and its metabolites with phospholipid membranes: An explanation for the peroxidation protective effect of the bioactive metabolite
- (2008) Fernando Santos et al. FREE RADICAL RESEARCH
- VDAC regulation: role of cytosolic proteins and mitochondrial lipids
- (2008) Tatiana K. Rostovtseva et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Mitochondrial Import and Accumulation of α-Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease Brain
- (2008) Latha Devi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Membrane lipids: where they are and how they behave
- (2008) Gerrit van Meer et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Tubulin binding blocks mitochondrial voltage-dependent anion channel and regulates respiration
- (2008) T. K. Rostovtseva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating
- (2008) R. Ujwal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Solution Structure of the Integral Human Membrane Protein VDAC-1 in Detergent Micelles
- (2008) S. Hiller et al. SCIENCE
- A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor
- (2008) Michael A. Hanson et al. STRUCTURE
- Interfacial Polar Interactions Affect Gramicidin Channel Kinetics
- (2007) Tatiana K. Rostovtseva et al. BIOPHYSICAL JOURNAL
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