The Voltage-dependent Anion Channel 1 Mediates Amyloid β Toxicity and Represents a Potential Target for Alzheimer Disease Therapy
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Voltage-dependent Anion Channel 1 Mediates Amyloid β Toxicity and Represents a Potential Target for Alzheimer Disease Therapy
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 290, Issue 52, Pages 30670-30683
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2015-11-06
DOI
10.1074/jbc.m115.691493
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The mitochondrial voltage-dependent anion channel 1 in tumor cells
- (2015) Varda Shoshan-Barmatz et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- A Direct Interaction Between Mitochondrial Proteins and Amyloid-β Peptide and its Significance for the Progression and Treatment of Alzheimer’s Disease
- (2015) O. Benek et al. CURRENT MEDICINAL CHEMISTRY
- Effects of ketone bodies in Alzheimer's disease in relation to neural hypometabolism, β-amyloid toxicity, and astrocyte function
- (2015) Leif Hertz et al. JOURNAL OF NEUROCHEMISTRY
- Mitochondrial Dysfunction Contributes to the Pathogenesis of Alzheimer’s Disease
- (2015) Fabian A. Cabezas-Opazo et al. Oxidative Medicine and Cellular Longevity
- Ca2+-mediated regulation of VDAC1 expression levels is associated with cell death induction
- (2014) Shira Weisthal et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Signaling pathway cross talk in Alzheimer’s disease
- (2014) Juan A Godoy et al. Cell Communication and Signaling
- Amyloid beta-induced glycogen synthase kinase 3β phosphorylated VDAC1 in Alzheimer's disease: Implications for synaptic dysfunction and neuronal damage
- (2013) P. Hemachandra Reddy BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
- (2013) Clifford R Jack et al. LANCET NEUROLOGY
- New findings concerning vertebrate porin II — On the relevance of glycine motifs of type-1 VDAC
- (2013) Friedrich P. Thinnes MOLECULAR GENETICS AND METABOLISM
- Human LilrB2 Is a -Amyloid Receptor and Its Murine Homolog PirB Regulates Synaptic Plasticity in an Alzheimer's Model
- (2013) T. Kim et al. SCIENCE
- VDAC1-based peptides: novel pro-apoptotic agents and potential therapeutics for B-cell chronic lymphocytic leukemia
- (2013) T Prezma et al. Cell Death & Disease
- Structure-based analysis of VDAC1: N-terminus location, translocation, channel gating and association with anti-apoptotic proteins
- (2012) Shay Geula et al. BIOCHEMICAL JOURNAL
- Mitochondrial VDAC1: Function in Cell Life and Death and a Target for Cancer Therapy
- (2012) V. Shoshan-Barmatz et al. CURRENT MEDICINAL CHEMISTRY
- Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease
- (2012) M. Manczak et al. HUMAN MOLECULAR GENETICS
- Mediation of the Antiapoptotic Activity of Bcl-xL Protein upon Interaction with VDAC1 Protein
- (2012) Nir Arbel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The β-Amyloid Hypothesis in Alzheimer's Disease: Seeing Is Believing
- (2012) Hank F. Kung ACS Medicinal Chemistry Letters
- Voltage-dependent anion channels (VDAC) in the plasma membrane play a critical role in apoptosis in differentiated hippocampal neurons but not in neural stem cells
- (2011) Nesar Akanda et al. CELL CYCLE
- Mitochondrial dysfunction and accumulation of the β-secretase-cleaved C-terminal fragment of APP in Alzheimer's disease transgenic mice
- (2011) Latha Devi et al. NEUROBIOLOGY OF DISEASE
- Brain Glucose Hypometabolism and Oxidative Stress in Preclinical Alzheimer's Disease
- (2010) Lisa Mosconi et al. Annals of the New York Academy of Sciences
- Voltage-dependent anion-selective channel (VDAC) in the plasma membrane
- (2010) Vito De Pinto et al. FEBS LETTERS
- Oligomerization of the Mitochondrial Protein Voltage-Dependent Anion Channel Is Coupled to the Induction of Apoptosis
- (2010) N. Keinan et al. MOLECULAR AND CELLULAR BIOLOGY
- VDAC, a multi-functional mitochondrial protein regulating cell life and death
- (2010) Varda Shoshan-Barmatz et al. MOLECULAR ASPECTS OF MEDICINE
- Amyloid-β-Derived Diffusible Ligands Cause Impaired Axonal Transport of Mitochondria in Neurons
- (2010) Xinglong Wang et al. Neurodegenerative Diseases
- Brain fuel metabolism, aging, and Alzheimer’s disease
- (2010) Stephen Cunnane et al. NUTRITION
- Protein-binding assays in biological liquids using microscale thermophoresis
- (2010) Christoph J. Wienken et al. Nature Communications
- Altered mitochondria, energy metabolism, voltage-dependent anion channel, and lipid rafts converge to exhaust neurons in Alzheimer’s disease
- (2009) Isidre Ferrer JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Voltage-dependent Anion Channel 1-based Peptides Interact with Bcl-2 to Prevent Antiapoptotic Activity
- (2009) Nir Arbel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Self-association of Transmembrane Domain 2 (TM2), but Not TM1, in Carnitine Palmitoyltransferase 1A
- (2009) Zsuzsanna A. Jenei et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The VDAC1 N-terminus is essential both for apoptosis and the protective effect of anti-apoptotic proteins
- (2009) S. Abu-Hamad et al. JOURNAL OF CELL SCIENCE
- VDAC and ERα interaction in caveolae from human cortex is altered in Alzheimer's disease
- (2009) Cristina M. Ramírez et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Neuroendocrine differentiation of LNCaP cells suggests: VDAC in the cell membrane is involved in the extrinsic apoptotic pathway
- (2009) Friedrich P. Thinnes MOLECULAR GENETICS AND METABOLISM
- Key regions of VDAC1 functioning in apoptosis induction and regulation by hexokinase
- (2008) Varda Shoshan-Barmatz et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Uncovering the role of VDAC in the regulation of cell life and death
- (2008) Varda Shoshan-Barmatz et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Regulation of hexokinase binding to VDAC
- (2008) John G. Pastorino et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Hexokinase-I Protection against Apoptotic Cell Death Is Mediated via Interaction with the Voltage-dependent Anion Channel-1
- (2008) Salah Abu-Hamad et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Voltage-dependent Anion Channel 1-based Peptides Interact with Hexokinase to Prevent Its Anti-apoptotic Activity
- (2008) Laetitia Arzoine et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now