Feasibility of large experimental animal models in testing novel therapeutic strategies for diabetes
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Title
Feasibility of large experimental animal models in testing novel therapeutic strategies for diabetes
Authors
Keywords
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Journal
World Journal of Diabetes
Volume 12, Issue 4, Pages 306-330
Publisher
Baishideng Publishing Group Inc.
Online
2021-04-08
DOI
10.4239/wjd.v12.i4.306
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Note: Only part of the references are listed.- Building Biomimetic Potency Tests for Islet Transplantation
- (2021) Aaron L. Glieberman et al. DIABETES
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- (2021) Isabella-Maria Giese et al. Frontiers in Immunology
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- (2020) Kristina G. Maxwell et al. Science Translational Medicine
- A novel cellular engineering approach to diabetes mellitus
- (2020) Gordon C. Weir Nature Reviews Endocrinology
- Long‐term follow‐up for the microbiological safety of clinical microencapsulated neonatal porcine islet transplantation
- (2020) Shinichi Matsumoto et al. XENOTRANSPLANTATION
- Pluripotent Stem Cell-Based Cell Therapy—Promise and Challenges
- (2020) Shinya Yamanaka Cell Stem Cell
- A Randomized Trial of Closed-Loop Control in Children with Type 1 Diabetes
- (2020) Marc D. Breton et al. NEW ENGLAND JOURNAL OF MEDICINE
- Generation of iPSC-derived insulin-producing cells from patients with type 1 and type 2 diabetes compared with healthy control
- (2020) Min Jung Kim et al. Stem Cell Research
- Evaluation of Multi-Layered Pancreatic Islets and Adipose-Derived Stem Cell Sheets Transplanted on Various Sites for Diabetes Treatment
- (2020) Yu Na Lee et al. Cells
- Extensive germline genome engineering in pigs
- (2020) Yanan Yue et al. Nature Biomedical Engineering
- Translating Embryogenesis to Generate Organoids: Novel Approaches to Personalized Medicine
- (2020) Sounak Sahu et al. iScience
- Part-revived pig brains raise slew of ethical quandaries
- (2019) Nita A. Farahany et al. NATURE
- A map of β-cell differentiation pathways supports cell therapies for diabetes
- (2019) Fabian J. Theis et al. NATURE
- Charting cellular identity during human in vitro β-cell differentiation
- (2019) Adrian Veres et al. NATURE
- Hurdles to Generating Human Islets in Animals via Blastocyst Complementation
- (2019) Tomoyuki Yamaguchi Current Diabetes Reports
- Distributions of endocrine cell clusters during porcine pancreatic development
- (2019) Masaki Nagaya et al. PLoS One
- WITHDRAWN: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9th edition
- (2019) Pouya Saeedi et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- An overview on small molecule-induced differentiation of mesenchymal stem cells into beta cells for diabetic therapy
- (2019) Nimshitha Pavathuparambil Abdul Manaph et al. Stem Cell Research & Therapy
- Six-Month Randomized, Multicenter Trial of Closed-Loop Control in Type 1 Diabetes
- (2019) Sue A. Brown et al. NEW ENGLAND JOURNAL OF MEDICINE
- Transplanting organs from pigs to humans
- (2019) Megan Sykes et al. Science Immunology
- Compensation of Disabled Organogeneses in Genetically Modified Pig Fetuses by Blastocyst Complementation
- (2019) Hitomi Matsunari et al. Stem Cell Reports
- Engineering Strategies to Improve Islet Transplantation for Type 1 Diabetes Therapy
- (2019) Alisa M. White et al. ACS Biomaterials-Science & Engineering
- Genetically engineered pigs as models for human disease
- (2018) Carolin Perleberg et al. Disease Models & Mechanisms
- Ethical rejections of xenotransplantation?
- (2018) John D Loike et al. EMBO REPORTS
- Effectiveness of bioengineered islet cell sheets for the treatment of diabetes mellitus
- (2018) Masaki Nagaya et al. JOURNAL OF SURGICAL RESEARCH
- Mapping the Teaching of Laboratory Animal Science and Medicine in the European Union and European Free Trade Area
- (2018) Despoina Iatridou et al. JOURNAL OF VETERINARY MEDICAL EDUCATION
- Animal models of obesity and diabetes mellitus
- (2018) Maximilian Kleinert et al. Nature Reviews Endocrinology
- The journey of islet cell transplantation and future development
- (2018) Anissa Gamble et al. Islets
- Systematic review of islet cryopreservation
- (2018) Greg G. Kojayan et al. Islets
- Artificial Pancreas or Novel Beta-Cell Replacement Therapies: a Race for Optimal Glycemic Control?
- (2018) Michiel F. Nijhoff et al. Current Diabetes Reports
- Neurog3-dependent pancreas dysgenesis causes ectopic pancreas inHes1mutant mice
- (2018) Mette C. Jørgensen et al. DEVELOPMENT
- Type 1 Diabetes in Children and Adolescents: A Position Statement by the American Diabetes Association
- (2018) Jane L. Chiang et al. DIABETES CARE
- Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques
- (2018) Matthew A. Bochenek et al. Nature Biomedical Engineering
- Pancreatic Islet Transplantation in Humans: Recent Progress and Future Directions
- (2018) Michael R Rickels et al. ENDOCRINE REVIEWS
- Closed-loop insulin delivery in suboptimally controlled type 1 diabetes: a multicentre, 12-week randomised trial
- (2018) Martin Tauschmann et al. LANCET
- Contribution of rat embryonic stem cells to xenogeneic chimeras in blastocyst or 8-cell embryo injection and aggregation
- (2018) Hiroki Okumura et al. XENOTRANSPLANTATION
- Diabetic phenotype of transgenic pigs introduced by dominant-negative mutant hepatocyte nuclear factor 1α
- (2017) Kazuhiro Umeyama et al. JOURNAL OF DIABETES AND ITS COMPLICATIONS
- Home use of a bihormonal bionic pancreas versus insulin pump therapy in adults with type 1 diabetes: a multicentre randomised crossover trial
- (2017) Firas H El-Khatib et al. LANCET
- Genetically Modified Pigs as Organ Donors for Xenotransplantation
- (2017) Magdalena Hryhorowicz et al. MOLECULAR BIOTECHNOLOGY
- Regenerative medicine: Interspecies pancreas transplants
- (2017) Qiao Zhou NATURE
- Interspecies organogenesis generates autologous functional islets
- (2017) Tomoyuki Yamaguchi et al. NATURE
- Xeno-created pancreata — the future of diabetes treatment?
- (2017) Alan Morris Nature Reviews Endocrinology
- Bioengineering of an Intraabdominal Endocrine Pancreas
- (2017) David A. Baidal et al. NEW ENGLAND JOURNAL OF MEDICINE
- Frequency of Evidence-Based Screening for Retinopathy in Type 1 Diabetes
- (2017) NEW ENGLAND JOURNAL OF MEDICINE
- The dawn of automated insulin delivery: A new clinical framework to conceptualize insulin administration
- (2017) Laurel H. Messer et al. PEDIATRIC DIABETES
- Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9
- (2017) Dong Niu et al. SCIENCE
- Interspecies Organogenesis-Derived Tissues for Transplantation
- (2017) Jon S. Odorico TRANSPLANTATION
- Regulation of Clinical Xenotransplantation—Time for a Reappraisal
- (2017) David K.C. Cooper et al. TRANSPLANTATION
- No PERV transmission during a clinical trial of pig islet cell transplantation
- (2017) Vladimir A. Morozov et al. VIRUS RESEARCH
- Apancreatic pigs cloned using Pdx1-disrupted fibroblasts created via TALEN-mediated mutagenesis
- (2017) Jin-Dan Kang et al. Oncotarget
- Sirolimus induces depletion of intracellular calcium stores and mitochondrial dysfunction in pancreatic beta cells
- (2017) Angela Lombardi et al. Scientific Reports
- The Munich MIDY Pig Biobank – A unique resource for studying organ crosstalk in diabetes
- (2017) Andreas Blutke et al. Molecular Metabolism
- A Review of the Current Challenges Associated with the Development of an Artificial Pancreas by a Double Subcutaneous Approach
- (2017) Sverre Christian Christiansen et al. Diabetes Therapy
- A Review of the Current Challenges Associated with the Development of an Artificial Pancreas by a Double Subcutaneous Approach
- (2017) Sverre Christian Christiansen et al. Diabetes Therapy
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- IDF Diabetes Atlas estimates of 2014 global health expenditures on diabetes
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- A transgenic-cloned pig model expressing non-fluorescent modified Plum
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- Advances in islet encapsulation technologies
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- (2016) Shinichi Matsumoto et al. Journal of Diabetes
- Day and night glycaemic control with a bionic pancreas versus conventional insulin pump therapy in preadolescent children with type 1 diabetes: a randomised crossover trial
- (2016) Steven J Russell et al. Lancet Diabetes & Endocrinology
- Clinical Benefit of Islet Xenotransplantation for the Treatment of Type 1 Diabetes
- (2016) Shinichi Matsumoto et al. EBioMedicine
- Antiaging Glycopeptide Protects Human Islets Against Tacrolimus-Related Injury and Facilitates Engraftment in Mice
- (2015) Boris L. Gala-Lopez et al. DIABETES
- Current State of Type 1 Diabetes Treatment in the U.S.: Updated Data From the T1D Exchange Clinic Registry
- (2015) Kellee M. Miller et al. DIABETES CARE
- Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro
- (2015) H. A. Russ et al. EMBO JOURNAL
- Estimated Life Expectancy in a Scottish Cohort With Type 1 Diabetes, 2008-2010
- (2015) Shona J. Livingstone et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Generation of α1,3-galactosyltransferase and cytidine monophospho-N-acetylneuraminic acid hydroxylase gene double-knockout pigs
- (2015) Shuji MIYAGAWA et al. JOURNAL OF REPRODUCTION AND DEVELOPMENT
- Production of transgenic cloned pigs expressing the far-red fluorescent protein monomeric Plum
- (2015) Masahito WATANABE et al. JOURNAL OF REPRODUCTION AND DEVELOPMENT
- Home Use of an Artificial Beta Cell in Type 1 Diabetes
- (2015) Hood Thabit et al. NEW ENGLAND JOURNAL OF MEDICINE
- A New System to Evaluate the Influence of Immunosuppressive Drugs on Pancreatic Islets Using Epigenetic Analysis in a 3-Dimensional Culture
- (2015) Masaki Nagaya et al. PANCREAS
- Genome-wide inactivation of porcine endogenous retroviruses (PERVs)
- (2015) L. Yang et al. SCIENCE
- Evaluation of human and non-human primate antibody binding to pig cells lacking GGTA1/CMAH/β4GalNT2 genes
- (2015) Jose L. Estrada et al. XENOTRANSPLANTATION
- Generation of Functional Human Pancreatic β Cells In Vitro
- (2014) Felicia W. Pagliuca et al. CELL
- Type 1 Diabetes Mellitus and Cardiovascular Disease
- (2014) Sarah D. de Ferranti et al. CIRCULATION
- Type 1 Diabetes Through the Life Span: A Position Statement of the American Diabetes Association
- (2014) Jane L. Chiang et al. DIABETES CARE
- Transgenic Pigs with Pancreas-specific Expression of Green Fluorescent Protein
- (2014) Hitomi MATSUNARI et al. JOURNAL OF REPRODUCTION AND DEVELOPMENT
- A Conserved Rule for Pancreatic Islet Organization
- (2014) Danh-Tai Hoang et al. PLoS One
- Clinical Porcine Islet Xenotransplantation Under Comprehensive Regulation
- (2014) S. Matsumoto et al. TRANSPLANTATION PROCEEDINGS
- Microbiological safety of the first clinical pig islet xenotransplantation trial in New Zealand
- (2014) Shaun Wynyard et al. XENOTRANSPLANTATION
- Encapsulated islets for diabetes therapy: History, current progress, and critical issues requiring solution
- (2013) David W. Scharp et al. ADVANCED DRUG DELIVERY REVIEWS
- Enhanced Oxygen Supply Improves Islet Viability in a New Bioartificial Pancreas
- (2013) Uriel Barkai et al. CELL TRANSPLANTATION
- Generation of Interleukin-2 Receptor Gamma Gene Knockout Pigs from Somatic Cells Genetically Modified by Zinc Finger Nuclease-Encoding mRNA
- (2013) Masahito Watanabe et al. PLoS One
- Blastocyst complementation generates exogenic pancreas in vivo in apancreatic cloned pigs
- (2013) H. Matsunari et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transplantation of human islets without immunosuppression
- (2013) B. Ludwig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Topographical Arrangement of α- and β-Cells Within Neo-islet Tissues Engineered by Islet Cell Sheet Transplantation in Mice
- (2013) H. Shimizu et al. TRANSPLANTATION PROCEEDINGS
- Extracellular factors and immunosuppressive drugs influencing insulin secretion of murine islets
- (2012) V. J. Auer et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Improvements in the Life Expectancy of Type 1 Diabetes: The Pittsburgh Epidemiology of Diabetes Complications Study Cohort
- (2012) R. G. Miller et al. DIABETES
- Improvement in Outcomes of Clinical Islet Transplantation: 1999-2010
- (2012) F. B. Barton et al. DIABETES CARE
- What's fueling the biotech engine—2011 to 2012
- (2012) Saurabh Aggarwal NATURE BIOTECHNOLOGY
- Alternative Transplantation Sites for Pancreatic Islet Grafts
- (2011) Elisa Cantarelli et al. Current Diabetes Reports
- A conditional knockout resource for the genome-wide study of mouse gene function
- (2011) William C. Skarnes et al. NATURE
- Unique Cellular and Mitochondrial Defects Mediate FK506-Induced Islet β-Cell Dysfunction
- (2011) Nassir Rostambeigi et al. TRANSPLANTATION
- Reversal of Diabetes by the Creation of Neo-Islet Tissues Into a Subcutaneous Site Using Islet Cell Sheets
- (2011) Takahiro Saito et al. TRANSPLANTATION
- Influence of microenvironment on engraftment of transplanted β-cells
- (2011) Per-Ola Carlsson UPSALA JOURNAL OF MEDICAL SCIENCES
- Glucose Intolerance and Reduced Proliferation of Pancreatic -Cells in Transgenic Pigs With Impaired Glucose-Dependent Insulinotropic Polypeptide Function
- (2010) S. Renner et al. DIABETES
- Characterizing sudden death and dead-in-bed syndrome in Type 1 diabetes: analysis from two childhood-onset Type 1 diabetes registries
- (2010) A. M. Secrest et al. DIABETIC MEDICINE
- Ethical implications of using the minipig in regulatory toxicology studies
- (2010) John Webster et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Bioengineering of a functional sheet of islet cells for the treatment of diabetes mellitus
- (2009) Hirofumi Shimizu et al. BIOMATERIALS
- Pig Embryonic Pancreatic Tissue as a Source for Transplantation in Diabetes: Transient Treatment With Anti-LFA1, Anti-CD48, and FTY720 Enables Long-Term Graft Maintenance in Mice With Only Mild Ongoing Immunosuppression
- (2009) D. Tchorsh-Yutsis et al. DIABETES
- Diagnosis and Classification of Diabetes Mellitus
- (2009) DIABETES CARE
- Dominant-negative mutant hepatocyte nuclear factor 1α induces diabetes in transgenic-cloned pigs
- (2009) Kazuhiro Umeyama et al. TRANSGENIC RESEARCH
- Optimal implantation site for pancreatic islet transplantation
- (2008) S. Merani et al. BRITISH JOURNAL OF SURGERY
- Mesenchymal stem cells: biology and clinical potential in type 1 diabetes therapy
- (2008) Meng Liu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- In vivo reprogramming of adult pancreatic exocrine cells to β-cells
- (2008) Qiao Zhou et al. NATURE
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