Evaluation of human and non-human primate antibody binding to pig cells lacking GGTA1/CMAH/β4GalNT2 genes

Literature WatchImplications for transplantation

(2014) A. Joseph Tector et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Reduced Binding of Human Antibodies to Cells From GGTA1/CMAH KO Pigs

(2014) C. Burlak et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Use of the CRISPR/Cas9 System to Produce Genetically Engineered Pigs from In Vitro-Derived Oocytes and Embryos1

(2014) Kristin M. Whitworth et al.   BIOLOGY OF REPRODUCTION

Creating Class I MHC–Null Pigs Using Guide RNA and the Cas9 Endonuclease

(2014) Luz M. Reyes et al.   JOURNAL OF IMMUNOLOGY

New National Allocation Policy for Deceased Donor Kidneys in the United States and Possible Effect on Patient Outcomes

(2014) A. K. Israni et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Efficient generation of genetically distinct pigs in a single pregnancy using multiplexed single-guide RNA and carbohydrate selection

(2014) Ping Li et al.   XENOTRANSPLANTATION

Potential deleterious role of anti-Neu5Gc antibodies in xenotransplantation

(2014) Apolline Salama et al.   XENOTRANSPLANTATION

Erythrocytes from GGTA1/CMAH knockout pigs: implications for xenotransfusion and testing in non-human primates

(2014) Zheng-Yu Wang et al.   XENOTRANSPLANTATION

The combinational use of CRISPR/Cas9-based gene editing and targeted toxin technology enables efficient biallelic knockout of the α-1,3-galactosyltransferase gene in porcine embryonic fibroblasts

(2014) Masahiro Sato et al.   XENOTRANSPLANTATION

Cloning and expression of porcine β1,4 N-acetylgalactosaminyl transferase encoding a new xenoreactive antigen

(2014) Guerard W. Byrne et al.   XENOTRANSPLANTATION

Efficient nonmeiotic allele introgression in livestock using custom endonucleases

(2013) W. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Double knockout pigs deficient in N-glycolylneuraminic acid and Galactose α-1,3-Galactose reduce the humoral barrier to xenotransplantation

(2013) Andrew J. Lutz et al.   XENOTRANSPLANTATION

Biallelic knockout of the α-1,3 galactosyltransferase gene in porcine liver-derived cells using zinc finger nucleases

(2012) Ping Li et al.   JOURNAL OF SURGICAL RESEARCH

Gene Targeting and Cloning in Pigs Using Fetal Liver Derived Cells

(2011) Sanjeev K. Waghmare et al.   JOURNAL OF SURGICAL RESEARCH

Potential impact of the non-human sialic acid N-glycolylneuraminic acid on transplant rejection risk

(2011) Vered Padler-Karavani et al.   XENOTRANSPLANTATION

Identification of New Carbohydrate and Membrane Protein Antigens in Cardiac Xenotransplantation

(2010) Guerard W. Byrne et al.   TRANSPLANTATION

Proteomic identification of non-Gal antibody targets after pig-to-primate cardiac xenotransplantation

(2008) Guerard W. Byrne et al.   XENOTRANSPLANTATION