Generation of Interleukin-2 Receptor Gamma Gene Knockout Pigs from Somatic Cells Genetically Modified by Zinc Finger Nuclease-Encoding mRNA

Knockout mice created by TALEN-mediated gene targeting

(2013) Young Hoon Sung et al.   NATURE BIOTECHNOLOGY

Il2rg Gene-Targeted Severe Combined Immunodeficiency Pigs

(2012) Shunichi Suzuki et al.   Cell Stem Cell

Biallelic knockout of the α-1,3 galactosyltransferase gene in porcine liver-derived cells using zinc finger nucleases

(2012) Ping Li et al.   JOURNAL OF SURGICAL RESEARCH

Efficient TALEN-mediated gene knockout in livestock

(2012) D. F. Carlson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning

(2011) Dongshan Yang et al.   CELL RESEARCH

CELL BIOLOGY SYMPOSIUM: Zinc finger nucleases to create custom-designed modifications in the swine (Sus scrofa) genome1,2

(2011) J. J. Whyte et al.   JOURNAL OF ANIMAL SCIENCE

Knockout rats generated by embryo microinjection of TALENs

(2011) Laurent Tesson et al.   NATURE BIOTECHNOLOGY

Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases

(2011) J. Hauschild et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Knockout of exogenous EGFP gene in porcine somatic cells using zinc-finger nucleases

(2010) Masahito Watanabe et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Glucose Intolerance and Reduced Proliferation of Pancreatic  -Cells in Transgenic Pigs With Impaired Glucose-Dependent Insulinotropic Polypeptide Function

(2010) S. Renner et al.   DIABETES

Targeted Genome Modification in Mice Using Zinc-Finger Nucleases

(2010) I. D. Carbery et al.   GENETICS

Transgenic pigs as models for translational biomedical research

(2010) Bernhard Aigner et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Gene targeting with zinc finger nucleases to produce cloned eGFP knockout pigs

(2010) Jeffrey J. Whyte et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Targeted integration in rat and mouse embryos with zinc-finger nucleases

(2010) Xiaoxia Cui et al.   NATURE BIOTECHNOLOGY

Transient cold shock enhances zinc-finger nuclease–mediated gene disruption

(2010) Yannick Doyon et al.   NATURE METHODS

Generation of Knockout Rats with X-Linked Severe Combined Immunodeficiency (X-SCID) Using Zinc-Finger Nucleases

(2010) Tomoji Mashimo et al.   PLoS One

Application of Genetically Modified and Cloned Pigs in Translational Research

(2009) Hitomi MATSUNARI et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Stimulation of homology-directed gene targeting at an endogenous human locus by a nicking endonuclease

(2009) G. P. van Nierop et al.   NUCLEIC ACIDS RESEARCH

Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases

(2009) Aron M. Geurts et al.   SCIENCE

Hemizygous minipigs produced by random gene insertion and handmade cloning express the Alzheimer’s disease-causing dominant mutation APPsw

(2009) Peter M. Kragh et al.   TRANSGENIC RESEARCH

Dominant-negative mutant hepatocyte nuclear factor 1α induces diabetes in transgenic-cloned pigs

(2009) Kazuhiro Umeyama et al.   TRANSGENIC RESEARCH

Effects of Recloning on the Efficiency of Production of α1,3-Galactosyltransferase Knockout Pigs

(2008) Tatsuya FUJIMURA et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs

(2008) C. S. Rogers et al.   SCIENCE

Transgenic-Cloned Pigs Systemically Expressing Red Fluorescent Protein, Kusabira-Orange

(2008) Hitomi Matsunari et al.   Cloning Stem Cells