Generation of viable PDX1 gene‐edited founder pigs as providers of nonmosaics

Generation of a TP53-modified porcine cancer model by CRISPR/Cas9-mediated gene modification in porcine zygotes via electroporation

(2018) Fuminori Tanihara et al.   PLoS One

Mosaicism in CRISPR/Cas9-mediated genome editing

(2018) Maryam Mehravar et al.   DEVELOPMENTAL BIOLOGY

Diabetic phenotype of transgenic pigs introduced by dominant-negative mutant hepatocyte nuclear factor 1α

(2017) Kazuhiro Umeyama et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Apancreatic pigs cloned using Pdx1-disrupted fibroblasts created via TALEN-mediated mutagenesis

(2017) Jin-Dan Kang et al.   Oncotarget

CRISPR-Cas9 mediated one-step disabling of pancreatogenesis in pigs

(2017) Jun Wu et al.   Scientific Reports

Experimental Diabetes Mellitus in Different Animal Models

(2016) Amin Al-awar et al.   Journal of Diabetes Research

Somatic cell reprogramming-free generation of genetically modified pigs

(2016) F. Tanihara et al.   Science Advances

Abnormal expression of DNA methyltransferases and genomic imprinting in cloned goat fibroblasts

(2015) Yongjie Wan et al.   CELL BIOLOGY INTERNATIONAL

Astaxanthin present in the maturation medium reduces negative effects of heat shock on the developmental competence of porcine oocytes

(2015) Lanh Thi Kim Do et al.   Reproductive Biology

Easy quantitative assessment of genome editing by sequence trace decomposition

(2014) Eva K. Brinkman et al.   NUCLEIC ACIDS RESEARCH

Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set

(2013) Mayuko Kurome et al.   BMC BIOTECHNOLOGY

Blastocyst complementation generates exogenic pancreas in vivo in apancreatic cloned pigs

(2013) H. Matsunari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Genetically engineered pig models for diabetes research

(2013) Eckhard Wolf et al.   TRANSGENIC RESEARCH

Permanent Neonatal Diabetes in INSC94Y Transgenic Pigs

(2012) S. Renner et al.   DIABETES

Genetically modified pigs for biomedical research

(2012) Yonglun Luo et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Generation of Rat Pancreas in Mouse by Interspecific Blastocyst Injection of Pluripotent Stem Cells

(2010) Toshihiro Kobayashi et al.   CELL

Effect of epigenetic regulation during swine embryogenesis and on cloning by nuclear transfer

(2010) Jianguo Zhao et al.   CELL AND TISSUE RESEARCH

Obesity and hyperinsulinemia in a family with pancreatic agenesis and MODY caused by the IPF1 mutation Pro63fsX60

(2010) Stefan S. Fajans et al.   Translational Research

Global estimates of the prevalence of diabetes for 2010 and 2030

(2009) J.E. Shaw et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Blastocyst Injection of Wild Type Embryonic Stem Cells Induces Global Corrections in Mdx Mice

(2009) Elizabeth Stillwell et al.   PLoS One

Genes controlling pancreas ontogeny

(2008) Claire Bonal et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY