Protective genes and pathways in Alzheimer’s disease: moving towards precision interventions

Therapeutic approaches targeting Apolipoprotein E function in Alzheimer’s disease

(2020) Tosha Williams et al.   Molecular Neurodegeneration

Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

(2020) Eric M. Reiman et al.   Nature Communications

APOEε4 potentiates the relationship between amyloid-β and tau pathologies

(2020) Joseph Therriault et al.   MOLECULAR PSYCHIATRY

Beyond the CNS: The many peripheral roles of APOE

(2020) Ana B. Martínez-Martínez et al.   NEUROBIOLOGY OF DISEASE

Association of Klotho-VS Heterozygosity With Risk of Alzheimer Disease in Individuals Who Carry APOE4

(2020) Michael E. Belloy et al.   JAMA Neurology

Longevity Gene KLOTHO and Alzheimer Disease—A Better Fate for Individuals Who Carry APOE ε4

(2020) Dena B. Dubal et al.   JAMA Neurology

Association of Early-Life Cognitive Enrichment With Alzheimer Disease Pathological Changes and Cognitive Decline

(2020) Shahram Oveisgharan et al.   JAMA Neurology

Modifiable Lifestyle Factors in Alzheimer Disease

(2020) Timothy J. Hohman et al.   JAMA Neurology

Involvement of Lipids in Alzheimer’s Disease Pathology and Potential Therapies

(2020) Hannah Chew et al.   Frontiers in Physiology

Sex Mediates Relationships Between Regional Tau Pathology and Cognitive Decline

(2020) Rachel F. Buckley et al.   ANNALS OF NEUROLOGY

Genetic variants and functional pathways associated with resilience to Alzheimer’s disease

(2020) Logan Dumitrescu et al.   BRAIN

Activation of the executioner caspases-3 and -7 promotes microglial pyroptosis in models of multiple sclerosis

(2020) Brienne A. McKenzie et al.   Journal of Neuroinflammation

Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer’s Dementia

(2020) Andrew R. Ouellette et al.   Cell Reports

Late-onset vs nonmendelian early-onset Alzheimer disease

(2020) Christiane Reitz et al.   Neurology-Genetics

Exome sequencing identifies three novel AD‐associated genes

(2020) Henne Holstege et al.   Alzheimers & Dementia

Decreased Serum Brain-Derived Neurotrophic Factor (BDNF) Levels in Patients with Alzheimer’s Disease (AD): A Systematic Review and Meta-Analysis

(2019) Ted Ng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

(2019) Iris E. Jansen et al.   NATURE GENETICS

Klotho allele status is not associated with Aβ and APOE ε4 related cognitive decline in preclinical Alzheimer’s disease

(2019) Tenielle Porter et al.   NEUROBIOLOGY OF AGING

Sex Differences in the Association of Global Amyloid and Regional Tau Deposition Measured By Positron Emission Tomography in Clinically Normal Older Adults

(2019) Rachel F. Buckley et al.   JAMA Neurology

REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer’s Disease

(2019) Katharina Meyer et al.   Cell Reports

Concepts for brain aging: resistance, resilience, reserve, and compensation

(2019) Thomas J. Montine et al.   Alzheimers Research & Therapy

Alzheimer’s disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph

(2019) Lorenza Magno et al.   Alzheimers Research & Therapy

KLOTHO heterozygosity attenuates APOE4-related amyloid burden in preclinical AD

(2019) Claire M. Erickson et al.   NEUROLOGY

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

(2019) Brian W. Kunkle et al.   NATURE GENETICS

The goddess who spins the thread of life: Klotho, psychiatric stress, and accelerated aging

(2019) Erika J. Wolf et al.   BRAIN BEHAVIOR AND IMMUNITY

ApoE4: an emerging therapeutic target for Alzheimer’s disease

(2019) Mirna Safieh et al.   BMC Medicine

The role of ABCA7 in Alzheimer’s disease: evidence from genomics, transcriptomics and methylomics

(2019) Arne De Roeck et al.   ACTA NEUROPATHOLOGICA

Single-cell transcriptomic analysis of Alzheimer’s disease

(2019) Hansruedi Mathys et al.   NATURE

TREML2 Mutation Mediate Alzheimer’s Disease Risk by Altering Neuronal Degeneration

(2019) Ya-Nan Song et al.   Frontiers in Neuroscience

Chronic traumatic encephalopathy is a common co-morbidity, but less frequent primary dementia in former soccer and rugby players

(2019) Edward B. Lee et al.   ACTA NEUROPATHOLOGICA

Sex differences in the genetic predictors of Alzheimer’s pathology

(2019) Logan Dumitrescu et al.   BRAIN

Endo-lysosomal dysregulations and late-onset Alzheimer’s disease: impact of genetic risk factors

(2019) Zoë P. Van Acker et al.   Molecular Neurodegeneration

Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies

(2019) Yu Yamazaki et al.   Nature Reviews Neurology

Lentiviral vector–mediated overexpression of Klotho in the brain improves Alzheimer's disease–like pathology and cognitive deficits in mice

(2019) Chen-Ye Zeng et al.   NEUROBIOLOGY OF AGING

Telomere shortening rate predicts species life span

(2019) Kurt Whittemore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion

(2019) Zeran Li et al.   ACTA NEUROPATHOLOGICA

Genetic resilience to Alzheimer's disease in APOE ε4 homozygotes: A systematic review

(2019) Aamira J. Huq et al.   Alzheimers & Dementia

Association of PICALM gene polymorphisms with Alzheimer's disease: Evidence from an updated meta-analysis

(2019) Fang-Fang Zeng et al.   Current Alzheimer Research

Peripheral versus central nervous system APOE in Alzheimer’s disease: Interplay across the blood-brain barrier

(2019) Dustin Chernick et al.   NEUROSCIENCE LETTERS

The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk

(2019) Yuetiva Deming et al.   Science Translational Medicine

Targeting the Synapse in Alzheimer’s Disease

(2019) Johanna Jackson et al.   Frontiers in Neuroscience

Resistance to autosomal dominant Alzheimer’s disease in an APOE3 Christchurch homozygote: a case report

(2019) Joseph F. Arboleda-Velasquez et al.   NATURE MEDICINE

Association of Apolipoprotein E ε4 With Medial Temporal Tau Independent of Amyloid-β

(2019) Joseph Therriault et al.   JAMA Neurology

Sex-specific genetic predictors of Alzheimer’s disease biomarkers

(2018) Yuetiva Deming et al.   ACTA NEUROPATHOLOGICA

Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms

(2018) Carlos Cruchaga et al.   Alzheimers & Dementia

Apolipoprotein E4 inhibits autophagy gene products through direct, specific binding to CLEAR motifs

(2018) Paul A. Parcon et al.   Alzheimers & Dementia

Effect of BDNF Val66Met on disease markers in dominantly inherited AD

(2018) Yen Ying Lim et al.   ANNALS OF NEUROLOGY

Apolipoprotein E, Receptors, and Modulation of Alzheimer’s Disease

(2018) Na Zhao et al.   BIOLOGICAL PSYCHIATRY

Cellular Trafficking of Amyloid Precursor Protein in Amyloidogenesis Physiological and Pathological Significance

(2018) Noralyn Basco Mañucat-Tan et al.   MOLECULAR NEUROBIOLOGY

TMEM106B haplotypes have distinct gene expression patterns in aged brain

(2018) Yingxue Ren et al.   Molecular Neurodegeneration

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

(2018) James J. Lee et al.   NATURE GENETICS

Synaptic dysfunction in Alzheimer's disease: the effects of amyloid beta on synaptic vesicle dynamics as a novel target for therapeutic intervention

(2018) Pavlos Alifragis et al.   Neural Regeneration Research

Resistance vs resilience to Alzheimer disease

(2018) Eider M. Arenaza-Urquijo et al.   NEUROLOGY

ABCA1 rs2230805 and rs2230806 common gene variants are associated with Alzheimer’s disease

(2018) Ágnes Fehér et al.   NEUROSCIENCE LETTERS

Does the heritability of cognitive abilities vary as a function of parental education? Evidence from a German twin sample

(2018) Marion Spengler et al.   PLoS One

Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau

(2018) Timothy J. Hohman et al.   JAMA Neurology

APOE Alleles and Extreme Human Longevity

(2018) Paola Sebastiani et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Klotho Deficiency Accelerates Stem Cells Aging by Impairing Telomerase Activity

(2018) Mujib Ullah et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

RAB10: an Alzheimer’s disease resilience locus and potential drug target

(2018) Justina Tavana et al.   Clinical Interventions in Aging

Characterization of pathogenic SORL1 genetic variants for association with Alzheimer’s disease: a clinical interpretation strategy

(2017) Henne Holstege et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Late onset Alzheimer’s disease genetics implicates microglial pathways in disease risk

(2017) Anastasia G. Efthymiou et al.   Molecular Neurodegeneration

BDNF at the synapse: why location matters

(2017) M Song et al.   MOLECULAR PSYCHIATRY

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

(2017) Yang Shi et al.   NATURE

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

(2017) Rebecca Sims et al.   NATURE GENETICS

Klotho, APOEε4, cognitive ability, brain size, atrophy, and survival: a study in the Aberdeen Birth Cohort of 1936

(2017) Clarisse F. de Vries et al.   NEUROBIOLOGY OF AGING

rs3851179 Polymorphism at 5′ to the PICALM Gene is Associated with Alzheimer and Parkinson Diseases in Brazilian Population

(2017) Cíntia Barros Santos-Rebouças et al.   NEUROMOLECULAR MEDICINE

Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice

(2017) Zoe A. Klein et al.   NEURON

Neuroprotective Effect of Ligustilide through Induction of α-Secretase Processing of Both APP and Klotho in a Mouse Model of Alzheimer’s Disease

(2017) Xi Kuang et al.   Frontiers in Aging Neuroscience

Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer’s disease resilience

(2017) Perry G. Ridge et al.   Genome Medicine

The DLGAP family: neuronal expression, function and role in brain disorders

(2017) Andreas H. Rasmussen et al.   Molecular Brain

Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score

(2017) Rahul S. Desikan et al.   PLOS MEDICINE

Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease

(2017) Scott C. Neu et al.   JAMA Neurology

Differential Aging Analysis in Human Cerebral Cortex Identifies Variants in TMEM106B and GRN that Regulate Aging Phenotypes

(2017) Herve Rhinn et al.   Cell Systems

A comprehensive study of the genetic impact of rare variants in SORL1 in European early-onset Alzheimer’s disease

(2016) Jan Verheijen et al.   ACTA NEUROPATHOLOGICA

Risk factor SORL1: from genetic association to functional validation in Alzheimer’s disease

(2016) Olav M. Andersen et al.   ACTA NEUROPATHOLOGICA

A loss of function variant in CASP7 protects against Alzheimer’s disease in homozygous APOE ε4 allele carriers

(2016) Kristin L. Ayers et al.   BMC GENOMICS

DoesBDNFVal66Met contribute to preclinical Alzheimer’s disease?

(2016) Ekaterina Rogaeva et al.   BRAIN

BDNFVal66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer’s disease

(2016) Yen Ying Lim et al.   BRAIN

Sex differences in the association between AD biomarkers and cognitive decline

(2016) Mary Ellen I. Koran et al.   Brain Imaging and Behavior

Apolipoprotein E as a Therapeutic Target in Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence

(2016) Yu Yamazaki et al.   CNS DRUGS

ABCA7 Mediates Phagocytic Clearance of Amyloid-β in the Brain

(2016) YuHong Fu et al.   JOURNAL OF ALZHEIMERS DISEASE

Impaired Autophagy in APOE4 Astrocytes

(2016) Shira Simonovitch et al.   JOURNAL OF ALZHEIMERS DISEASE

Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer’s Disease

(2016) Vincent Chouraki et al.   JOURNAL OF ALZHEIMERS DISEASE

ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology

(2016) Nobutaka Sakae et al.   JOURNAL OF NEUROSCIENCE

Genetic landscape of APOE in human longevity revealed by high-throughput sequencing

(2016) Seungjin Ryu et al.   MECHANISMS OF AGEING AND DEVELOPMENT

SORL1 Is Associated with the Risk of Late-Onset Alzheimer’s Disease: a Replication Study and Meta-Analyses

(2016) Cheng-Cheng Zhang et al.   MOLECULAR NEUROBIOLOGY

Apolipoprotein E lipoprotein particles inhibit amyloid-β uptake through cell surface heparan sulphate proteoglycan

(2016) Yuan Fu et al.   Molecular Neurodegeneration

ApoE2 and Alzheimer′s disease: time to take a closer look

(2016) Liqin Zhao et al.   Neural Regeneration Research

Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation

(2016) Honghua Zheng et al.   NEUROBIOLOGY OF AGING

Mutation analysis of the MS4A and TREM gene clusters in a case-control Alzheimer's disease data set

(2016) Mahdi Ghani et al.   NEUROBIOLOGY OF AGING

ABCA7 p.G215S as potential protective factor for Alzheimer's disease

(2016) Celeste Sassi et al.   NEUROBIOLOGY OF AGING

Asymptomatic Alzheimer disease

(2016) Timothy J. Hohman et al.   NEUROLOGY

Gain of BDNF Function in Engrafted Neural Stem Cells Promotes the Therapeutic Potential for Alzheimer’s Disease

(2016) Cheng-Chun Wu et al.   Scientific Reports

Loss-of-function mutation in ABCA1 and risk of Alzheimer's disease and cerebrovascular disease

(2015) Liv Tybjærg Nordestgaard et al.   Alzheimers & Dementia

Coding mutations inSORL1and Alzheimer disease

(2015) Badri N. Vardarajan et al.   ANNALS OF NEUROLOGY

Protective variant for hippocampal atrophy identified by whole exome sequencing

(2015) Kwangsik Nho et al.   ANNALS OF NEUROLOGY

Common polygenic variation enhances risk prediction for Alzheimer’s disease

(2015) Valentina Escott-Price et al.   BRAIN

Amyloid-Beta Protein Clearance and Degradation (ABCD) Pathways and their Role in Alzheimer’s Disease

(2015) Robert Baranello et al.   Current Alzheimer Research

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance

(2015) Zhen Zhao et al.   NATURE NEUROSCIENCE

Protective alleles and modifier variants in human health and disease

(2015) Andrew R. Harper et al.   NATURE REVIEWS GENETICS

The APP A673T frequency differs between Nordic countries

(2015) Jonas Mengel-From et al.   NEUROBIOLOGY OF AGING

Rarity of the Alzheimer Disease–ProtectiveAPPA673T Variant in the United States

(2015) Li-San Wang et al.   JAMA Neurology

Longitudinal Inflammation, Cognitive Decline, and Alzheimer’s Disease: A Mini-Review

(2014) B M Bettcher et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Molecular Mechanisms of Alzheimer Disease Protection by the A673T Allele of Amyloid Precursor Protein

(2014) Janice A. Maloney et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Alzheimer Disease Protective Mutation A2T Modulates Kinetic and Thermodynamic Properties of Amyloid-β (Aβ) Aggregation

(2014) Iryna Benilova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of SORL1 in Alzheimer’s Disease

(2014) Rui-Hua Yin et al.   MOLECULAR NEUROBIOLOGY

The Role of PICALM in Alzheimer’s Disease

(2014) Wei Xu et al.   MOLECULAR NEUROBIOLOGY

REST and stress resistance in ageing and Alzheimer’s disease

(2014) Tao Lu et al.   NATURE

Genetics of PICALM Expression and Alzheimer's Disease

(2014) Ishita Parikh et al.   PLoS One

Effect of BDNF Val66Met on Memory Decline and Hippocampal Atrophy in Prodromal Alzheimer’s Disease: A Preliminary Study

(2014) Yen Ying Lim et al.   PLoS One

Dysfunction of phospholipase Cγ in immune disorders and cancer

(2014) Hans Koss et al.   TRENDS IN BIOCHEMICAL SCIENCES

ER to synapse trafficking of NMDA receptors

(2014) Martin Horak et al.   Frontiers in Cellular Neuroscience

TMEM106B expression is reduced in Alzheimer’s disease brains

(2014) Jun-ichi Satoh et al.   Alzheimers Research & Therapy

Prevalence of mixed pathologies in the aging brain

(2014) Jasmin Rahimi et al.   Alzheimers Research & Therapy

Alzheimer’s disease drug-development pipeline: few candidates, frequent failures

(2014) Jeffrey L Cummings et al.   Alzheimers Research & Therapy

Life Extension Factor Klotho Enhances Cognition

(2014) Dena B. Dubal et al.   Cell Reports

Clathrin adaptor CALM/PICALM is associated with neurofibrillary tangles and is cleaved in Alzheimer’s brains

(2013) Kunie Ando et al.   ACTA NEUROPATHOLOGICA

Deletion of Abca7 Increases Cerebral Amyloid-  Accumulation in the J20 Mouse Model of Alzheimer's Disease

(2013) W. S. Kim et al.   JOURNAL OF NEUROSCIENCE

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

(2013) Clifford R Jack et al.   LANCET NEUROLOGY

Significance of the anti-aging protein Klotho

(2013) Miribane Dërmaku-Sopjani et al.   MOLECULAR MEMBRANE BIOLOGY

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

(2013) Chia-Chen Liu et al.   Nature Reviews Neurology

Missense variant in TREML2 protects against Alzheimer's disease

(2013) Bruno A. Benitez et al.   NEUROBIOLOGY OF AGING

Serum Brain-Derived Neurotrophic Factor and the Risk for Dementia

(2013) Galit Weinstein et al.   JAMA Neurology

The role of ABCB1 and ABCA1 in beta-amyloid clearance at the neurovascular unit in Alzheimer's disease

(2013) Ayman ElAli et al.   Frontiers in Physiology

Abca1 Deficiency Affects Alzheimer's Disease-Like Phenotype in Human ApoE4 But Not in ApoE3-Targeted Replacement Mice

(2012) N. F. Fitz et al.   JOURNAL OF NEUROSCIENCE

Cognitive reserve in ageing and Alzheimer's disease

(2012) Yaakov Stern   LANCET NEUROLOGY

High frequency of potentially pathogenic SORL1 mutations in autosomal dominant early-onset Alzheimer disease

(2012) C Pottier et al.   MOLECULAR PSYCHIATRY

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

(2012) Thorlakur Jonsson et al.   NATURE

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rare Variants in APP, PSEN1 and PSEN2 Increase Risk for AD in Late-Onset Alzheimer's Disease Families

(2012) Carlos Cruchaga et al.   PLoS One

Expression of Novel Alzheimer’s Disease Risk Genes in Control and Alzheimer’s Disease Brains

(2012) Celeste M. Karch et al.   PLoS One

Relationship Between Education and Dementia

(2011) Emily Schoenhofen Sharp et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Ecology of the Aging Human Brain

(2011) Joshua A. Sonnen   ARCHIVES OF NEUROLOGY

Asymptomatic Alzheimers Disease: A Prodrome or a State of Resilience?

(2011) I. Driscoll et al.   Current Alzheimer Research

Impact of SORL1 Single Nucleotide Polymorphisms on Alzheimer’s Disease Cerebrospinal Fluid Markers

(2011) Panagiotis Alexopoulos et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

The Master Negative Regulator REST/NRSF Controls Adult Neurogenesis by Restraining the Neurogenic Program in Quiescent Stem Cells

(2011) Z. Gao et al.   JOURNAL OF NEUROSCIENCE

Caspase signalling controls microglia activation and neurotoxicity

(2011) Miguel A. Burguillos et al.   NATURE

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

(2011) Paul Hollingworth et al.   NATURE GENETICS

CDK5 Is Essential for Soluble Amyloid β-Induced Degradation of GKAP and Remodeling of the Synaptic Actin Cytoskeleton

(2011) Francesco Roselli et al.   PLoS One

Rab GEFs and GAPs

(2010) Francis Barr et al.   CURRENT OPINION IN CELL BIOLOGY

ATP-binding Cassette Transporter A1 Mediates the Beneficial Effects of the Liver X Receptor Agonist GW3965 on Object Recognition Memory and Amyloid Burden in Amyloid Precursor Protein/Presenilin 1 Mice

(2010) James J. Donkin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Review Article: Genetics of Alzheimer Disease

(2010) Lynn M. Bekris et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

Distribution and Expression of Picalm in Alzheimer Disease

(2010) Shabnam Baig et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

BDNF Overexpression in the Forebrain Rescues Huntington's Disease Phenotypes in YAC128 Mice

(2010) Y. Xie et al.   JOURNAL OF NEUROSCIENCE

TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers

(2010) N. Finch et al.   NEUROLOGY

A simple role for BDNF in learning and memory?

(2010) Cunha   Frontiers in Molecular Neuroscience

TREM and TREM-like receptors in inflammation and disease

(2009) Jill W Ford et al.   CURRENT OPINION IN IMMUNOLOGY

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

(2009) Clifford R Jack et al.   LANCET NEUROLOGY

The heritability of general cognitive ability increases linearly from childhood to young adulthood

(2009) C M A Haworth et al.   MOLECULAR PSYCHIATRY

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

The expression of type III hyperlipoproteinemia: involvement of lipolysis genes

(2008) Peter Henneman et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Influence of SORL1 gene variants: Association with CSF amyloid-β products in probable Alzheimer's disease

(2008) Heike Kölsch et al.   NEUROSCIENCE LETTERS