Neuroprotective Effect of Ligustilide through Induction of α-Secretase Processing of Both APP and Klotho in a Mouse Model of Alzheimer’s Disease
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Neuroprotective Effect of Ligustilide through Induction of α-Secretase Processing of Both APP and Klotho in a Mouse Model of Alzheimer’s Disease
Authors
Keywords
-
Journal
Frontiers in Aging Neuroscience
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2017-11-02
DOI
10.3389/fnagi.2017.00353
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Amyloid Clearance as a Treatment Target Against Alzheimer's Disease
- (2018) Alexander Kurz et al. JOURNAL OF ALZHEIMERS DISEASE
- Microglia-Synapse Pathways: Promising Therapeutic Strategy for Alzheimer’s Disease
- (2017) Jingdun Xie et al. Biomed Research International
- Fibroblast growth factor 23 signaling in hippocampal cells: impact on neuronal morphology and synaptic density
- (2016) Niko Hensel et al. JOURNAL OF NEUROCHEMISTRY
- Inadequate supply of vitamins and DHA in the elderly: Implications for brain aging and Alzheimer-type dementia
- (2015) M. Hasan Mohajeri et al. NUTRITION
- Transmembrane Amyloid-Related Proteins in CSF as Potential Biomarkers for Alzheimer’s Disease
- (2015) Inmaculada Lopez-Font et al. Frontiers in Neurology
- Ligustilide ameliorates neuroinflammation and brain injury in focal cerebral ischemia/reperfusion rats: involvement of inhibition of TLR4/peroxiredoxin 6 signaling
- (2014) Xi Kuang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Latrepirdine (Dimebon®), a potential Alzheimer therapeutic, regulates autophagy and neuropathology in an Alzheimer mouse model
- (2013) John W. Steele et al. Autophagy
- Restoration of klotho gene expression induces apoptosis and autophagy in gastric cancer cells: tumor suppressive role of klotho in gastric cancer
- (2013) Biao Xie et al. Cancer Cell International
- Genetic Deficiency of Anti-Aging GeneKlothoExacerbates Early Nephropathy in STZ-Induced Diabetes in Male Mice
- (2013) Yi Lin et al. ENDOCRINOLOGY
- Arctigenin Effectively Ameliorates Memory Impairment in Alzheimer's Disease Model Mice Targeting Both -Amyloid Production and Clearance
- (2013) Z. Zhu et al. JOURNAL OF NEUROSCIENCE
- Autophagy is involved in oligodendroglial precursor-mediated clearance of amyloid peptide
- (2013) Wenxia Li et al. Molecular Neurodegeneration
- Klotho upregulation contributes to the neuroprotection of ligustilide in an Alzheimer's disease mouse model
- (2013) Xi Kuang et al. NEUROBIOLOGY OF AGING
- Autophagy in aging and neurodegenerative diseases: implications for pathogenesis and therapy
- (2013) Chen-Chen Tan et al. NEUROBIOLOGY OF AGING
- Soluble Alpha-APP (sAPPalpha) Regulates CDK5 Expression and Activity in Neurons
- (2013) Daniela Hartl et al. PLoS One
- Insulin and IGF-1 signalling: longevity, protein homoeostasis and Alzheimer's disease
- (2012) Cora O'Neill et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Nuclear localization of Klotho in brain: an anti-aging protein
- (2012) Dwight C. German et al. NEUROBIOLOGY OF AGING
- KL1 Internal Repeat Mediates Klotho Tumor Suppressor Activities and Inhibits bFGF and IGF-I Signaling in Pancreatic Cancer
- (2011) L. Abramovitz et al. CLINICAL CANCER RESEARCH
- A small-molecule enhancer of autophagy decreases levels of Aβ and APP-CTF via Atg5-dependent autophagy pathway
- (2011) Yuan Tian et al. FASEB JOURNAL
- Z-ligustilide isolated from Radix Angelicae sinensis ameliorates the memory impairment induced by scopolamine in mice
- (2011) Li-Ling Cheng et al. FITOTERAPIA
- Functions of Aβ, sAPPα and sAPPβ : similarities and differences
- (2011) Stéphanie Chasseigneaux et al. JOURNAL OF NEUROCHEMISTRY
- Identification and biology of α-secretase
- (2011) Valérie Vingtdeux et al. JOURNAL OF NEUROCHEMISTRY
- Genes Involved in Cerebrospinal Fluid Production as Candidate Genes for Late-Onset Alzheimer's Disease: A Hypothesis
- (2011) Peter Wostyn et al. JOURNAL OF NEUROGENETICS
- Autophagy failure in Alzheimer's disease—locating the primary defect
- (2011) Ralph A. Nixon et al. NEUROBIOLOGY OF DISEASE
- Klotho and the Aging Process
- (2011) Makoto Kuro-o KOREAN JOURNAL OF INTERNAL MEDICINE
- Z-ligustilide attenuates lipopolysaccharide-induced proinflammatory response via inhibiting NF-κB pathway in primary rat microglia
- (2010) Jing Wang et al. ACTA PHARMACOLOGICA SINICA
- Cilostazol prevents amyloid β peptide25-35-induced memory impairment and oxidative stress in mice
- (2010) Masayuki Hiramatsu et al. BRITISH JOURNAL OF PHARMACOLOGY
- Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-β peptide degradation
- (2010) Valérie Vingtdeux et al. FASEB JOURNAL
- Molecular dynamics simulations of Aβ fibril interactions with β-sheet breaker peptides
- (2010) Neil J. Bruce et al. PEPTIDES
- Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease
- (2010) Patricia Spilman et al. PLoS One
- Autophagy protects neuron from Aβ-induced cytotoxicity
- (2009) Shih-Ya Hung et al. Autophagy
- Reduced IGF-1 Signaling Delays Age-Associated Proteotoxicity in Mice
- (2009) Ehud Cohen et al. CELL
- Klotho is a substrate for α-, β- and γ-secretase
- (2009) Laura Bloch et al. FEBS LETTERS
- The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid β accumulation in mice
- (2008) Fiona Pickford et al. JOURNAL OF CLINICAL INVESTIGATION
- Morphological and biochemical signs of age-related neurodegenerative changes in klotho mutant mice
- (2008) M. Shiozaki et al. NEUROSCIENCE
- Postischemic administration of Z-Ligustilide ameliorates cognitive dysfunction and brain damage induced by permanent forebrain ischemia in rats
- (2007) X KUANG et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now