Clathrin adaptor CALM/PICALM is associated with neurofibrillary tangles and is cleaved in Alzheimer’s brains

Binding of the three-repeat domain of tau to phospholipid membranes induces an aggregated-like state of the protein

(2012) Georg Künze et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Role of Phosphatidylinositol Clathrin Assembly Lymphoid-Myeloid Leukemia (PICALM) in Intracellular Amyloid Precursor Protein (APP) Processing and Amyloid Plaque Pathogenesis

(2012) Qingli Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduction of AP180 and CALM Produces Defects in Synaptic Vesicle Size and Density

(2012) Ronald S. Petralia et al.   NEUROMOLECULAR MEDICINE

The Clathrin Assembly Protein PICALM Is Required for Erythroid Maturation and Transferrin Internalization in Mice

(2012) Mai Suzuki et al.   PLoS One

Accelerated Human Mutant Tau Aggregation by Knocking Out Murine Tau in a Transgenic Mouse Model

(2011) Kunie Ando et al.   AMERICAN JOURNAL OF PATHOLOGY

Clathrin-mediated endocytic proteins are upregulated in the cortex of the Tg2576 mouse model of Alzheimer’s disease-like amyloid pathology

(2011) Rhian S. Thomas et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Molecular Basis for the Endocytosis of Small R-SNAREs by the Clathrin Adaptor CALM

(2011) Sharon E. Miller et al.   CELL

Lessons from yeast for clathrin-mediated endocytosis

(2011) Douglas R. Boettner et al.   NATURE CELL BIOLOGY

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

(2011) Paul Hollingworth et al.   NATURE GENETICS

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

(2011) Eric Karran et al.   NATURE REVIEWS DRUG DISCOVERY

Granulovacuolar Degenerations Appear in Relation to Hippocampal Phosphorylated Tau Accumulation in Various Neurodegenerative Disorders

(2011) Yuu Yamazaki et al.   PLoS One

Functional Links Between A  Toxicity, Endocytic Trafficking, and Alzheimer's Disease Risk Factors in Yeast

(2011) S. Treusch et al.   SCIENCE

AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer’s disease and other tauopathies

(2010) Valérie Vingtdeux et al.   ACTA NEUROPATHOLOGICA

Neuronal activity and the expression of clathrin-assembly protein AP180

(2010) Fangbai Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genetic evidence for the involvement of lipid metabolism in Alzheimer's disease

(2010) Lesley Jones et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimer's disease

(2010) Koen Bossers et al.   BRAIN

Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease

(2010) Sudha Seshadri   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Distribution and Expression of Picalm in Alzheimer Disease

(2010) Shabnam Baig et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Association of CLU and PICALM variants with Alzheimer's disease

(2010) M. Ilyas Kamboh et al.   NEUROBIOLOGY OF AGING

The Unfolded Protein Response Is Activated in Pretangle Neurons in Alzheimer's Disease Hippocampus

(2009) Jeroen J.M. Hoozemans et al.   AMERICAN JOURNAL OF PATHOLOGY

Calpain Hydrolysis of α- and β2-Adaptins Decreases Clathrin-dependent Endocytosis and May Promote Neurodegeneration

(2009) Nikita Rudinskiy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Membrane Cholesterol Might Render Mature Hippocampal Neurons More Susceptible to  -Amyloid-Induced Calpain Activation and Tau Toxicity

(2009) A. M. Nicholson et al.   JOURNAL OF NEUROSCIENCE

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

Clathrin Assembly Protein AP180 and CALM Differentially Control Axogenesis and Dendrite Outgrowth in Embryonic Hippocampal Neurons

(2008) I. Bushlin et al.   JOURNAL OF NEUROSCIENCE