Gain of BDNF Function in Engrafted Neural Stem Cells Promotes the Therapeutic Potential for Alzheimer’s Disease

Aβ induces oxidative stress in senescence-accelerated (SAMP8) mice

(2015) Kurara Takagane et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

BDNF over-expression increases olfactory bulb granule cell dendritic spine density in vivo

(2015) B. McDole et al.   NEUROSCIENCE

Genetic manipulation of adult-born hippocampal neurons rescues memory in a mouse model of Alzheimer’s disease

(2014) Kevin Richetin et al.   BRAIN

Maturation of AMPAR Composition and the GABAAR Reversal Potential in hPSC-Derived Cortical Neurons

(2014) M. R. Livesey et al.   JOURNAL OF NEUROSCIENCE

A Time Course Analysis of the Electrophysiological Properties of Neurons Differentiated from Human Induced Pluripotent Stem Cells (iPSCs)

(2014) Deborah Prè et al.   PLoS One

Concise Review: Generation of Neurons From Somatic Cells of Healthy Individuals and Neurological Patients Through Induced Pluripotency or Direct Conversion

(2014) Iván Velasco et al.   STEM CELLS

Regulation of synaptic plasticity and cognition by SUMO in normal physiology and Alzheimer's disease

(2014) Linda Lee et al.   Scientific Reports

Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models

(2014) Mathew Blurton-Jones et al.   Stem Cell Research & Therapy

Neural Stem Cells as a Therapeutic Approach for Amyotrophic Lateral Sclerosis

(2013) Laura Ferraiuolo et al.   MOLECULAR THERAPY

Therapeutic Potential of Genetically Modified Mesenchymal Stem Cells After Neonatal Hypoxic-Ischemic Brain Damage

(2013) Cindy TJ van Velthoven et al.   MOLECULAR THERAPY

BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases

(2013) Bai Lu et al.   NATURE REVIEWS NEUROSCIENCE

Human umbilical cord mesenchymal stem cell-derived neuron-like cells rescue memory deficits and reduce amyloid-beta deposition in an AβPP/PS1 transgenic mouse model

(2013) Hui Yang et al.   Stem Cell Research & Therapy

Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43

(2012) I.-F. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concise Review: Can Stem Cells be Used to Treat or Model Alzheimer's Disease?

(2012) Wesley W. Chen et al.   STEM CELLS

Neuronal replacement in the injured olfactory bulb☆

(2011) Huan Liu et al.   EXPERIMENTAL NEUROLOGY

Engraftment of human nasal olfactory stem cells restores neuroplasticity in mice with hippocampal lesions

(2011) Emmanuel Nivet et al.   JOURNAL OF CLINICAL INVESTIGATION

PKC   Activation Prevents Synaptic Loss, A  Elevation, and Cognitive Deficits in Alzheimer's Disease Transgenic Mice

(2011) J. Hongpaisan et al.   JOURNAL OF NEUROSCIENCE

Adult hippocampal neurogenesis and its role in Alzheimer's disease

(2011) Yangling Mu et al.   Molecular Neurodegeneration

Rapid and Efficient Generation of Functional Motor Neurons From Human Pluripotent Stem Cells Using Gene Delivered Transcription Factor Codes

(2011) Mark E Hester et al.   MOLECULAR THERAPY

Potential therapeutic uses of BDNF in neurological and psychiatric disorders

(2011) Alan H. Nagahara et al.   NATURE REVIEWS DRUG DISCOVERY

Combined Effects of Hematopoietic Progenitor Cell Mobilization from Bone Marrow by Granulocyte Colony Stimulating Factor and AMD3100 and Chemotaxis into the Brain Using Stromal Cell-Derived Factor-1α in an Alzheimer's Disease Mouse Model

(2011) Ji-Woong Shin et al.   STEM CELLS

Age and gene overexpression interact to abolish nesting behavior in Tg2576 amyloid precursor protein (APP) mice

(2010) Daniel W. Wesson et al.   BEHAVIOURAL BRAIN RESEARCH

Low proliferation and differentiation capacities of adult hippocampal stem cells correlate with memory dysfunction in humans

(2010) R. Coras et al.   BRAIN

Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents

(2010) Stephen M. Massa et al.   JOURNAL OF CLINICAL INVESTIGATION

Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U

(2010) Kuen-Jer Tsai et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Communication via gap junctions underlies early functional and beneficial interactions between grafted neural stem cells and the host

(2010) J. Jaderstad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivo cellular imaging pinpoints the role of reactive oxygen species in the early steps of adult hematopoietic reconstitution

(2009) D. Lewandowski et al.   BLOOD

Astrocyte function and role in motor neuron disease: A future therapeutic target?

(2009) Daniel Blackburn et al.   GLIA

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

(2009) Alan H Nagahara et al.   NATURE MEDICINE

Computational Influence of Adult Neurogenesis on Memory Encoding

(2009) James B. Aimone et al.   NEURON

Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease

(2009) M. Blurton-Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcium Imaging of Cortical Neurons using Fura-2 AM

(2009) Odmara L Barreto-Chang et al.   Jove-Journal of Visualized Experiments

Genetic Modification of Neural Stem Cells

(2008) Rahul Jandial et al.   MOLECULAR THERAPY