TMEM106B expression is reduced in Alzheimer’s disease brains

TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions

(2014) Michael D. Gallagher et al.   ACTA NEUROPATHOLOGICA

TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia

(2014) Marka van Blitterswijk et al.   ACTA NEUROPATHOLOGICA

TMEM106B and APOE polymorphisms interact to confer risk for late-onset Alzheimer’s disease in Han Chinese

(2013) Rui-Chun Lu et al.   JOURNAL OF NEURAL TRANSMISSION

TMEM106B p.T185S regulates TMEM106B protein levels: implications for frontotemporal dementia

(2013) Alexandra M. Nicholson et al.   JOURNAL OF NEUROCHEMISTRY

Expression of TMEM106B, the frontotemporal lobar degeneration-associated protein, in normal and diseased human brain

(2013) Johanna I Busch et al.   Acta Neuropathologica Communications

The frontotemporal lobar degeneration risk factor, TMEM106B, regulates lysosomal morphology and function

(2012) Owen A. Brady et al.   HUMAN MOLECULAR GENETICS

TMEM106B, the Risk Gene for Frontotemporal Dementia, Is Regulated by the microRNA-132/212 Cluster and Affects Progranulin Pathways

(2012) A. S. Chen-Plotkin et al.   JOURNAL OF NEUROSCIENCE

TMEM106B risk variant is implicated in the pathologic presentation of Alzheimer disease

(2012) N. J. Rutherford et al.   NEUROLOGY

Regulation of Progranulin Expression in Human Microglia and Proteolysis of Progranulin by Matrix Metalloproteinase-12 (MMP-12)

(2012) Hyeon-Sook Suh et al.   PLoS One

Dystrophic neurites express C9orf72 in Alzheimer's disease brains

(2012) Jun-ichi Satoh et al.   Alzheimers Research & Therapy

Progranulin Is a Chemoattractant for Microglia and Stimulates Their Endocytic Activity

(2011) Fiona Pickford et al.   AMERICAN JOURNAL OF PATHOLOGY

TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort

(2011) Julie van der Zee et al.   BRAIN

TMEM106B a Novel Risk Factor for Frontotemporal Lobar Degeneration

(2011) Julie van der Zee et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Progranulin expression in brain tissue and cerebrospinal fluid levels in multiple sclerosis

(2011) Marco Vercellino et al.   Multiple Sclerosis Journal

Risk genotypes at TMEM106B are associated with cognitive impairment in amyotrophic lateral sclerosis

(2010) Ryan Vass et al.   ACTA NEUROPATHOLOGICA

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

(2010) Vivianna M Van Deerlin et al.   NATURE GENETICS

TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers

(2010) N. Finch et al.   NEUROLOGY

Sortilin-Mediated Endocytosis Determines Levels of the Frontotemporal Dementia Protein, Progranulin

(2010) Fenghua Hu et al.   NEURON

Granulovacuolar degeneration (GVD) bodies of Alzheimer's disease (AD) resemble late-stage autophagic organelles

(2010) K. E. Funk et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Progranulin expression correlates with dense-core amyloid plaque burden in Alzheimer disease mouse models

(2009) Sandra Pereson et al.   JOURNAL OF PATHOLOGY