Amino acid-derived defense metabolites from plants: A potential source to facilitate novel antimicrobial development
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Title
Amino acid-derived defense metabolites from plants: A potential source to facilitate novel antimicrobial development
Authors
Keywords
plants, plant defense, amino acids, secondary metabolites, antibiotic resistance
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume -, Issue -, Pages 100438
Publisher
Elsevier BV
Online
2021-02-24
DOI
10.1016/j.jbc.2021.100438
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Note: Only part of the references are listed.- A modular cloning toolkit for genome editing in plants
- (2020) Florian Hahn et al. BMC PLANT BIOLOGY
- Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
- (2020) David J. Newman et al. JOURNAL OF NATURAL PRODUCTS
- Synthesis of proteins by automated flow chemistry
- (2020) N. Hartrampf et al. SCIENCE
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- (2020) Berit Troost et al. Scientific Reports
- The antifungal plant defensin HsAFP1 induces autophagy, vacuolar dysfunction and cell cycle impairment in yeast
- (2020) Caroline Struyfs et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Interaction of dicentrinone, an antitrypanosomal aporphine alkaloid isolated from Ocotea puberula (Lauraceae), in cell membrane models at the air-water interface
- (2020) Henrique Barbosa et al. BIOORGANIC CHEMISTRY
- Indole alkaloids: 2012 until now, highlighting the new chemical structures and biological activities
- (2020) Pauline Fagundes Rosales et al. FITOTERAPIA
- Yeast as a promising heterologous host for steroid bioproduction
- (2020) Shanhui Xu et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Cepharanthine: a review of the antiviral potential of a Japanese-approved alopecia drug in COVID-19
- (2020) Moshe Rogosnitzky et al. Pharmacological Reports
- Antiviral activity of lycorine against Zika virus in vivo and in vitro
- (2020) Huini Chen et al. VIROLOGY
- Divergent synthesis of complex diterpenes through a hybrid oxidative approach
- (2020) Xiao Zhang et al. SCIENCE
- The Immune Escape Mechanisms of Mycobacterium Tuberculosis
- (2019) Weijie Zhai et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Progress and Challenges in Aminoacyl-tRNA Synthetase-based Therapeutics
- (2019) Christopher S. Francklyn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Up-regulation of glycolipid transfer protein by bicyclol causes spontaneous restriction of hepatitis C virus replication
- (2019) Meng-Hao Huang et al. Acta Pharmaceutica Sinica B
- Global expansion and redistribution of Aedes-borne virus transmission risk with climate change
- (2019) Sadie J. Ryan et al. PLoS Neglected Tropical Diseases
- Computational screening of medicinal plant phytochemicals to discover potent pan-serotype inhibitors against dengue virus
- (2019) Muhammad Tahir ul Qamar et al. Scientific Reports
- Antifungal activity and mechanism of action of Ou-gon (Scutellaria root extract) components against pathogenic fungi
- (2019) Xia Da et al. Scientific Reports
- Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus
- (2019) Luke Whitesell et al. Nature Communications
- Expression, purification and characterization of a recombinant antimicrobial peptide Hispidalin in Pichia pastoris
- (2019) De-Mei Meng et al. PROTEIN EXPRESSION AND PURIFICATION
- The arginine deiminase operon is responsible for a fitness trade-off in extended-spectrum β-lactamase encoding strains of Escherichia coli
- (2019) Typhaine Billard-Pomares et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Allicin inhibits Pseudomonas aeruginosa virulence by suppressing the rhl and pqs quorum-sensing systems
- (2019) Zhimin Xu et al. CANADIAN JOURNAL OF MICROBIOLOGY
- Fixing the Unfixable: The Art of Optimizing Natural Products for Human Medicine
- (2019) Audrey E. Yñigez-Gutierrez et al. JOURNAL OF MEDICINAL CHEMISTRY
- The landscape of natural product diversity and their pharmacological relevance from a focus on the Dictionary of Natural Products®
- (2019) François Chassagne et al. PHYTOCHEMISTRY REVIEWS
- Papain-like cysteine proteases prepare plant cyclic peptide precursors for cyclization
- (2019) Fabian B. H. Rehm et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- On the Emergence of Candida auris: Climate Change, Azoles, Swamps, and Birds
- (2019) Arturo Casadevall et al. mBio
- Synthetic biology strategies for microbial biosynthesis of plant natural products
- (2019) Aaron Cravens et al. Nature Communications
- Identification of candidate genes involved in steroidal alkaloids biosynthesis in organ-specific transcriptomes of Veratrum nigrum L.
- (2019) Magdalena Szeliga et al. GENE
- Cepharanthine: An update of its mode of action, pharmacological properties and medical applications
- (2019) Christian Bailly PHYTOMEDICINE
- Screening of Antiviral Components of Ma Huang Tang and Investigation on the Ephedra Alkaloids Efficacy on Influenza Virus Type A
- (2019) Wenyang Wei et al. Frontiers in Pharmacology
- Tailoring of microbes for the production of high value plant-derived compounds: From pathway engineering to fermentative production
- (2019) Aravind Madhavan et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Natural product derived privileged scaffolds in drug discovery
- (2019) Emma K Davison et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- How structural subtleties lead to molecular diversity for the type III polyketide synthases
- (2019) Hiroyuki Morita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Resveratrol analogues present effective antileishmanial activity against promastigotes and amastigotes from distinct Leishmania species by multitarget action in the parasites
- (2019) Luciana Maria Ribeiro Antinarelli et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- A gold mine for drug discovery: Strategies to develop cyclic peptides into therapies
- (2019) Xiaoshu Jing et al. MEDICINAL RESEARCH REVIEWS
- Cyclotides: From Structure to Function
- (2019) Simon J. de Veer et al. CHEMICAL REVIEWS
- Antiviral activity of amides and carboxamides of quinolizidine alkaloid (−)-cytisine against human influenza virus A (H1N1) and parainfluenza virus type 3
- (2019) Victoria A. Fedorova et al. NATURAL PRODUCT RESEARCH
- Characterization of steroid 5α-reductase involved in α-tomatine biosynthesis in tomatoes
- (2019) Ryota Akiyama et al. Plant Biotechnology
- Enantioselective synthesis and anti-parasitic properties of aporphine natural products
- (2019) Pauline Pieper et al. TETRAHEDRON
- Antimicrobial activity of resveratrol-derived monomers and dimers against foodborne pathogens
- (2019) Luce M. Mattio et al. Scientific Reports
- Recent advances in modular co-culture engineering for synthesis of natural products
- (2019) Rufeng Wang et al. CURRENT OPINION IN BIOTECHNOLOGY
- Antimicrobial and structural insights of a new snakin-like peptide isolated from Peltophorum dubium (Fabaceae)
- (2018) Susana Rodríguez-Decuadro et al. AMINO ACIDS
- Ribosomally-synthesised cyclic peptides from plants as drug leads and pharmaceutical scaffolds
- (2018) David J. Craik et al. BIOORGANIC & MEDICINAL CHEMISTRY
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- (2018) Gabriel B. Taveira et al. BIOSCIENCE REPORTS
- Measuring and mapping the global burden of antimicrobial resistance
- (2018) Simon I. Hay et al. BMC Medicine
- Design, synthesis and evaluation of amino-substituted 1 H -phenalen-1-ones as anti-leishmanial agents
- (2018) Mónica Blanco Freijo et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
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- (2018) Kengo Akagawa et al. JOURNAL OF ORGANIC CHEMISTRY
- Biodegradable Nanocomposite Antimicrobials for the Eradication of Multidrug-Resistant Bacterial Biofilms without Accumulated Resistance
- (2018) Ryan F. Landis et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The multi-faceted potential of plant-derived metabolites as antimicrobial agents against multidrug-resistant pathogens
- (2018) Jonghoon Shin et al. MICROBIAL PATHOGENESIS
- Nepenthe-Like Indole Alkaloids with Antimicrobial Activity from Ervatamia chinensis
- (2018) Hao-Fei Yu et al. ORGANIC LETTERS
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- (2018) Federico Scossa et al. PLANTA MEDICA
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- (2018) Nicole C. Parsley et al. PHYTOCHEMISTRY
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- (2018) Akihito Ochiai et al. Scientific Reports
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- (2018) James P. Tam et al. Scientific Reports
- How Does the Sweet Violet (Viola odorata L.) Fight Pathogens and Pests – Cyclotides as a Comprehensive Plant Host Defense System
- (2018) Blazej Slazak et al. Frontiers in Plant Science
- Characterization of Hydroxyproline-Containing Hairpin-Like Antimicrobial Peptide EcAMP1-Hyp from Barnyard Grass (Echinochloa crusgalli L.) Seeds: Structural Identification and Comparative Analysis of Antifungal Activity
- (2018) Eugene Rogozhin et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Antibacterial Activity of Discaria americana Gillies ex Hook (Rhamnaceae)
- (2018) Janice Dahmer et al. JOURNAL OF ETHNOPHARMACOLOGY
- Activity of Thioallyl Compounds From Garlic Against Giardia duodenalis Trophozoites and in Experimental Giardiasis
- (2018) Raúl Argüello-García et al. Frontiers in Cellular and Infection Microbiology
- The Phenylpropanoid Case – It Is Transport That Matters
- (2018) Wanda Biała et al. Frontiers in Plant Science
- Bicyclol Attenuates Liver Inflammation Induced by Infection of Hepatitis C Virus via Repressing ROS-Mediated Activation of MAPK/NF-κB Signaling Pathway
- (2018) Hu Li et al. Frontiers in Pharmacology
- Enhancement of the antimycobacterial activity of macrophages by ajoene
- (2017) Ji-Ae Choi et al. Innate Immunity
- The inhibitory performance of flavonoid cyanidin-3-sambubiocide against H274Y mutation in H1N1 influenza virus
- (2017) S. Kannan et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Antiplasmodial Activity, Cytotoxicity and Structure-Activity Relationship Study of Cyclopeptide Alkaloids
- (2017) Emmy Tuenter et al. MOLECULES
- Diallylthiosulfinate (Allicin), a Volatile Antimicrobial from Garlic (Allium sativum), Kills Human Lung Pathogenic Bacteria, Including MDR Strains, as a Vapor
- (2017) Jana Reiter et al. MOLECULES
- Phytochemical composition and in vitro screening of the antimicrobial activity of essential oils on oral pathogenic bacteria
- (2017) Roberta Tardugno et al. NATURAL PRODUCT RESEARCH
- Emerging infectious diseases: A proactive approach
- (2017) David E. Bloom et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Biosynthesis of cabbage phytoalexins from indole glucosinolate
- (2017) Andrew P. Klein et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alkaloids as the natural anti-influenza virus agents: a systematic review
- (2017) Mohammad-Taghi Moradi et al. Toxin Reviews
- Garlic Organosulfur Compounds Reduce Inflammation and Oxidative Stress during Dengue Virus Infection
- (2017) Alex Hall et al. Viruses-Basel
- Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid
- (2017) Youngzee Song et al. Nature Communications
- Pathogen inactivation of cruciferous phytoalexins: detoxification reactions, enzymes and inhibitors
- (2017) M. Soledade C. Pedras et al. RSC Advances
- In Vitro Evaluations and In Vivo Toxicity and Efficacy Studies of MFM501 against MRSA
- (2017) Saiful Azmi Johari et al. Biomed Research International
- Antiviral Properties of the Natural Polyphenols Delphinidin and Epigallocatechin Gallate against the Flaviviruses West Nile Virus, Zika Virus, and Dengue Virus
- (2017) Ángela Vázquez-Calvo et al. Frontiers in Microbiology
- Bleogens: Cactus-Derived Anti-Candida Cysteine-Rich Peptides with Three Different Precursor Arrangements
- (2017) Shining Loo et al. Frontiers in Plant Science
- Indole Alkaloids from Plants as Potential Leads for Antidepressant Drugs: A Mini Review
- (2017) Hazrulrizawati A. Hamid et al. Frontiers in Pharmacology
- Potential and use of bacterial small RNAs to combat drug resistance: a systematic review
- (2017) Hung Chan et al. Infection and Drug Resistance
- Looking to nature for a new concept in antimicrobial treatments: isoflavonoids from Cytisus striatus as antibiotic adjuvants against MRSA
- (2017) Ana Cristina Abreu et al. Scientific Reports
- A broad range quorum sensing inhibitor working through sRNA inhibition
- (2017) Tim H. Jakobsen et al. Scientific Reports
- Total Synthesis of Viniferifuran, Resveratrol-Piceatannol Hybrid, Anigopreissin A and Analogues - Investigation of Demethylation Strategies
- (2016) Duc Duy Vo et al. ADVANCED SYNTHESIS & CATALYSIS
- Antiviral activity of selected flavonoids against Chikungunya virus
- (2016) Rafidah Lani et al. ANTIVIRAL RESEARCH
- Thionin-like peptide from Capsicum annuum fruits: mechanism of action and synergism with fluconazole against Candida species
- (2016) Gabriel B. Taveira et al. BMC MICROBIOLOGY
- Screening of Natural Products and Derivatives for the Identification of RND Efflux Pump Inhibitors
- (2016) Debarati Choudhury et al. COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
- Reactivation of latent HIV-1 in latently infected cells by coumarin compounds: Hymecromone and ScoparoneReactivation of Latent HIV-1 in Latently Infected Cells by Coumarin Compounds: Hymecromone and Scoparone
- (2016) Xian Li et al. CURRENT HIV RESEARCH
- Engineered knottin peptides as diagnostics, therapeutics, and drug delivery vehicles
- (2016) James R Kintzing et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Exploring Polypharmacology in Drug Discovery and Repurposing Using the CANDO Platform
- (2016) Gaurav Chopra et al. CURRENT PHARMACEUTICAL DESIGN
- Bispidine as a Privileged Scaffold
- (2016) Isabelle Tomassoli et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Sphingolipids as targets for treatment of fungal infections
- (2016) Rodrigo Rollin-Pinheiro et al. Future Medicinal Chemistry
- Allicin Induces Thiol Stress in Bacteria throughS-Allylmercapto Modification of Protein Cysteines
- (2016) Alexandra Müller et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Natural Products as Sources of New Drugs from 1981 to 2014
- (2016) David J. Newman et al. JOURNAL OF NATURAL PRODUCTS
- Hepatitis C virus dynamics and cellular gene expression in uPA-SCID chimeric mice with humanized livers during intravenous silibinin monotherapy
- (2016) S. DebRoy et al. JOURNAL OF VIRAL HEPATITIS
- The Antiviral Alkaloid Berberine Reduces Chikungunya Virus-Induced Mitogen-Activated Protein Kinase Signaling
- (2016) Finny S. Varghese et al. JOURNAL OF VIROLOGY
- A Single Transcript CRISPR-Cas9 System for Efficient Genome Editing in Plants
- (2016) Xu Tang et al. Molecular Plant
- The radish defensins RsAFP1 and RsAFP2 act synergistically with caspofungin against Candida albicans biofilms
- (2016) Kim Vriens et al. PEPTIDES
- Cyclopeptide alkaloids
- (2016) Emmy Tuenter et al. PHYTOCHEMISTRY REVIEWS
- The Metabolic Plant Feedback Hypothesis: How Plant Secondary Metabolites Nonspecifically Impact Human Health
- (2016) Jürg Gertsch PLANTA MEDICA
- Expression, purification and characterization of the recombinant cysteine-rich antimicrobial peptide snakin-1 in Pichia pastoris
- (2016) Md. Ruhul Kuddus et al. PROTEIN EXPRESSION AND PURIFICATION
- Studying of cellular interaction of hairpin-like peptide EcAMP1 from barnyard grass (Echinochloa crusgalliL.) seeds with plant pathogenic fungusFusarium solaniusing microscopy techniques
- (2016) Alexey S. Vasilchenko et al. SCANNING
- Animal models to achieve an HIV cure
- (2016) Nitasha Kumar et al. Current Opinion in HIV and AIDS
- Ginkgotides: Proline-Rich Hevein-Like Peptides from Gymnosperm Ginkgo biloba
- (2016) Ka H. Wong et al. Frontiers in Plant Science
- Plant Alkaloids as Antiplatelet Agent: Drugs of the Future in the Light of Recent Developments
- (2016) Qurrat-Ul- Ain et al. Frontiers in Pharmacology
- Mode of action and membrane specificity of the antimicrobial peptide snakin-2
- (2016) Vera Herbel et al. PeerJ
- Therapeutic Potential of Spirooxindoles as Antiviral Agents
- (2016) Na Ye et al. ACS Infectious Diseases
- Nanoparticle-Stabilized Capsules for the Treatment of Bacterial Biofilms
- (2015) Bradley Duncan et al. ACS Nano
- 2-(3′-Indolyl)-N-arylthiazole-4-carboxamides: Synthesis and evaluation of antibacterial and anticancer activities
- (2015) Mukund P. Tantak et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Insights on Antimicrobial Resistance, Biofilms and the Use of Phytochemicals as New Antimicrobial Agents
- (2015) Anabela Borges et al. CURRENT MEDICINAL CHEMISTRY
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- (2015) Phuong Quoc Thuc Nguyen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Novel Penicillin-Type Analogues Bearing a Variable Substituted 2-Azetidinone Ring at Position 6: Synthesis and Biological Evaluation
- (2015) Margherita De Rosa et al. MOLECULES
- Recombinant Production of Snakin-2 (an Antimicrobial Peptide from Tomato) in E. coli and Analysis of Its Bioactivity
- (2015) Vera Herbel et al. MOLECULES
- Phytoalexins: Current Progress and Future Prospects
- (2015) Philippe Jeandet MOLECULES
- Plant alkaloids as drug leads for Alzheimer's disease
- (2015) Yu Pong Ng et al. NEUROCHEMISTRY INTERNATIONAL
- Effects of cyclotides against cutaneous infections caused by Staphylococcus aureus
- (2015) Isabel C.M. Fensterseifer et al. PEPTIDES
- The bitter side of the nightshades: Genomics drives discovery in Solanaceae steroidal alkaloid metabolism
- (2015) P.D. Cárdenas et al. PHYTOCHEMISTRY
- The Plant Peptidome: An Expanding Repertoire of Structural Features and Biological Functions
- (2015) Patrizia Tavormina et al. PLANT CELL
- De novo production of the plant-derived alkaloid strictosidine in yeast
- (2015) Stephanie Brown et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evolutionarily conserved phenylpropanoid pattern on angiosperm pollen
- (2015) Christin Fellenberg et al. TRENDS IN PLANT SCIENCE
- Lead Optimization of Spiropyrazolopyridones: A New and Potent Class of Dengue Virus Inhibitors
- (2015) Bin Zou et al. ACS Medicinal Chemistry Letters
- Bioinspired iterative synthesis of polyketides
- (2015) Kuan Zheng et al. Frontiers in Chemistry
- Substituent effects on the binding of natural product anthocyanidin inhibitors to influenza neuraminidase with mass spectrometry
- (2014) Kavya Swaminathan et al. ANALYTICA CHIMICA ACTA
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- (2014) Kiyoshi Ohyama et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Metabolic and functional diversity of saponins, biosynthetic intermediates and semi-synthetic derivatives
- (2014) Tessa Moses et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Evaluation of the best method to assess antibiotic potentiation by phytochemicals against Staphylococcus aureus
- (2014) Ana Cristina Abreu et al. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
- Probing the aurone scaffold against Plasmodium falciparum: Design, synthesis and antimalarial activity
- (2014) Marta P. Carrasco et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis, biological evaluation and molecular docking of novel chalcone–coumarin hybrids as anticancer and antimalarial agents
- (2014) Ratchanok Pingaew et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- B-ring modified aurones as promising allosteric inhibitors of hepatitis C virus RNA-dependent RNA polymerase
- (2014) Amel Meguellati et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Discovery and characterization of pseudocyclic cystine-knot α-amylase inhibitors with high resistance to heat and proteolytic degradation
- (2014) Phuong Q. T. Nguyen et al. FEBS Journal
- Antileishmanial phytochemical phenolics: Molecular docking to potential protein targets
- (2014) Ifedayo Victor Ogungbe et al. JOURNAL OF MOLECULAR GRAPHICS & MODELLING
- New Horizons for Old Drugs and Drug Leads
- (2014) Gordon M. Cragg et al. JOURNAL OF NATURAL PRODUCTS
- Anti-malarial activity of indole alkaloids isolated from Aspidosperma olivaceum
- (2014) Talita PC Chierrito et al. MALARIA JOURNAL
- Antiprotozoal Activity of Buxus sempervirens and Activity-Guided Isolation of O-tigloylcyclovirobuxeine-B as the Main Constituent Active against Plasmodium falciparum
- (2014) Julia Althaus et al. MOLECULES
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- (2014) Philippe Jeandet et al. MOLECULES
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- (2014) Jan Borlinghaus et al. MOLECULES
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- (2014) Jessica M. A. Blair et al. NATURE REVIEWS MICROBIOLOGY
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- (2014) Moshe Rogosnitzky et al. Pharmacological Reports
- Alkaloids as drug leads – A predictive structural and biodiversity-based analysis
- (2014) Vafa Amirkia et al. Phytochemistry Letters
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- (2014) Zsuzsanna Rozmer et al. PHYTOCHEMISTRY REVIEWS
- Identification of Natural Compound Inhibitors for Multidrug Efflux Pumps of Escherichia coli and Pseudomonas aeruginosa Using In Silico High-Throughput Virtual Screening and In Vitro Validation
- (2014) Vasudevan Aparna et al. PLoS One
- An unusual indole alkaloid with anti-adenovirus and anti-HSV activities from Alstonia scholaris
- (2014) Li Zhang et al. TETRAHEDRON LETTERS
- Identification and Synthesis of Quinolizidines with Anti-Influenza A Virus Activity
- (2014) Zhao Dang et al. ACS Medicinal Chemistry Letters
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- (2014) Wenjuan Dong et al. Scientific Reports
- Phosphoinositide-mediated oligomerization of a defensin induces cell lysis
- (2014) Ivan KH Poon et al. eLife
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- (2013) Ulisses E.C. Confalonieri et al. ACTA TROPICA
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- (2013) Kavya Swaminathan et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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- (2013) Ryo Nakabayashi et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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- (2013) Kieron M. G. O'Connell et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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- (2013) Jian-Ping Dai et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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- (2013) M. Soledade C. Pedras et al. BIOORGANIC & MEDICINAL CHEMISTRY
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- (2013) Mahesh S. Majik et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
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- (2013) Aaron G. Poth et al. BIOPOLYMERS
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- (2013) Gabriel B. Taveira et al. BIOPOLYMERS
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- (2013) Doriane E Djeussi et al. BMC Complementary and Alternative Medicine
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- (2013) Cristian G Bologa et al. CURRENT OPINION IN PHARMACOLOGY
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- (2013) David Gutiérrez et al. EXPERIMENTAL PARASITOLOGY
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- (2013) Robert Nawrot et al. FOLIA MICROBIOLOGICA
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- (2013) Markus Albert JOURNAL OF EXPERIMENTAL BOTANY
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- (2013) Gil Belofsky et al. JOURNAL OF NATURAL PRODUCTS
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- (2013) Fatemeh Daneshmand et al. NATURAL PRODUCT RESEARCH
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- (2013) M. E. Moldrup et al. PLANT CELL
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- (2013) Anna A. Slavokhotova et al. PLANT MOLECULAR BIOLOGY
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- (2013) Julie K. Klint et al. PLoS One
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- (2013) Caroline E. Zetterström et al. PLoS One
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- (2013) V. Haridas et al. PLoS Neglected Tropical Diseases
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- (2012) Tim Holm Jakobsen et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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- (2012) Peter B. Oparin et al. BIOCHEMICAL JOURNAL
- Cyclic Peptides as Therapeutic Agents and Biochemical Tools
- (2012) Sang-Hoon Joo Biomolecules & Therapeutics
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- (2012) David J. Craik et al. Chemical Biology & Drug Design
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- (2012) Gerhard Bringmann et al. CHEMISTRY-A EUROPEAN JOURNAL
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- (2012) George P. Tegos et al. CURRENT PHARMACEUTICAL DESIGN
- The interconnection between biofilm formation and horizontal gene transfer
- (2012) Jonas Stenløkke Madsen et al. FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY
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- (2012) K. M. Bedard et al. JOURNAL OF VIROLOGY
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- (2012) Maria Saavedra et al. Medicinal Chemistry
- Target profiling of 4-hydroxyderricin in S. aureus reveals seryl-tRNA synthetase binding and inhibition by covalent modification
- (2012) Oliver A. Battenberg et al. Molecular BioSystems
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- (2012) Karin Thevissen et al. MOLECULAR MICROBIOLOGY
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- (2012) Michael Wink MOLECULES
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- (2012) Sergey V. Pronin et al. Nature Chemistry
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- (2012) A.A. Astafieva et al. PEPTIDES
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- (2012) Tobias Munde et al. PHYTOCHEMISTRY
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- (2012) C. H. Saslis-Lagoudakis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2011) Gabriel Mitchell et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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- (2011) Sónia Troeira Henriques et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2011) Svetlana B. Nolde et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2011) Ben C.L. Chan et al. JOURNAL OF ETHNOPHARMACOLOGY
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- (2011) Eric M. Guantai et al. JOURNAL OF MEDICINAL CHEMISTRY
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- (2011) Romain Haudecoeur et al. JOURNAL OF MEDICINAL CHEMISTRY
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- (2011) Pierre-Marie Allard et al. JOURNAL OF NATURAL PRODUCTS
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- (2011) Yiu-Ming Ng et al. JOURNAL OF STRUCTURAL BIOLOGY
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- (2011) M. SOLEDADE C. PEDRAS et al. MOLECULAR PLANT PATHOLOGY
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- (2011) Shahriar Khadem et al. MOLECULES
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- (2011) M. Soledade C. Pedras et al. NATURAL PRODUCT REPORTS
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- (2011) Panomwan Panseeta et al. PHYTOCHEMISTRY
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- (2011) Zhenchuan Mao et al. PHYTOPARASITICA
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- (2011) Leena Pohjala et al. PLoS One
- Phytoalexins in defense against pathogens
- (2011) Ishita Ahuja et al. TRENDS IN PLANT SCIENCE
- Distribution and Functions of Sterols and Sphingolipids
- (2011) J. T. Hannich et al. Cold Spring Harbor Perspectives in Biology
- A bacterial platform for fermentative production of plant alkaloids
- (2011) Akira Nakagawa et al. Nature Communications
- Site-Specific Effects of Diselenide Bridges on the Oxidative Folding of a Cystine Knot Peptide, ω-Selenoconotoxin GVIA
- (2010) Konkallu Hanumae Gowd et al. BIOCHEMISTRY
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- (2010) Kyoko Hayashi et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
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- (2010) Juan C. Cedrón et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Evaluation of toxicity and antitumor activity of cycloviolacin O2 in mice
- (2010) Robert Burman et al. BIOPOLYMERS
- Overview on Plant Antimicrobial Peptides
- (2010) Ana Maria Benko-Iseppon et al. CURRENT PROTEIN & PEPTIDE SCIENCE
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- (2010) M. Pranting et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
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- (2010) Luciano Vozzolo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2010) Nicole L. van der Weerden et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site
- (2010) Qing Li et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Airway Mucus Function and Dysfunction
- (2010) John V. Fahy et al. NEW ENGLAND JOURNAL OF MEDICINE
- Garlic as an inhibitor ofPseudomonas aeruginosaquorum sensing in cystic fibrosis-a pilot randomized controlled trial
- (2010) Alan R. Smyth et al. PEDIATRIC PULMONOLOGY
- In vivoantimalarial activities of glycoalkaloids isolated from Solanaceae plants
- (2010) Yan Chen et al. PHARMACEUTICAL BIOLOGY
- Non-protein amino acids: plant, soil and ecosystem interactions
- (2010) Valerie Vranova et al. PLANT AND SOIL
- Efficacy and Safety of Imiquimod Versus Podophyllotoxin in the Treatment of Anogenital Warts
- (2010) Peter Komericki et al. SEXUALLY TRANSMITTED DISEASES
- A Meta-analysis of the Effectiveness of Albendazole Compared with Metronidazole as Treatments for Infections with Giardia duodenalis
- (2010) Shahram Solaymani-Mohammadi et al. PLoS Neglected Tropical Diseases
- Integrated Oxidative Folding of Cysteine/Selenocysteine Containing Peptides: Improving Chemical Synthesis of Conotoxins
- (2009) Aleksandra Walewska et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Global Factors Driving Emerging Infectious Diseases
- (2009) A. Alonso Aguirre et al. Annals of the New York Academy of Sciences
- Despite a Conserved Cystine Knot Motif, Different Cyclotides Have Different Membrane Binding Modes
- (2009) Conan K. Wang et al. BIOPHYSICAL JOURNAL
- X-ray scattering studies of model lipid membrane interacting with purothionin provide support for a previously proposed mechanism of membrane lysis
- (2009) Jaroslaw Majewski et al. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
- A novel antifungal hevein-type peptide fromTriticum kiharaeseeds with a unique 10-cysteine motif
- (2009) Tatyana I. Odintsova et al. FEBS Journal
- The antifungal plant defensin RsAFP2 from radish induces apoptosis in a metacaspase independent way inCandida albicans
- (2009) An M. Aerts et al. FEBS LETTERS
- Bicyclol: A Novel Drug for Treating Chronic Viral Hepatitis B and C
- (2009) Geng Liu Medicinal Chemistry
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- (2009) Thomas Vogt Molecular Plant
- In Vitro Activity of the Antifungal Plant Defensin RsAFP2 against Candida Isolates and Its In Vivo Efficacy in Prophylactic Murine Models of Candidiasis
- (2008) P. M. Tavares et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Inactivation of Microbial Arginine Deiminases byl-Canavanine
- (2008) Ling Li et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Chemical and biomimetic total syntheses of natural and engineered MCoTI cyclotides
- (2008) Panumart Thongyoo et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Expression and functional characterization of the plant antimicrobial snakin-1 and defensin recombinant proteins
- (2008) Natalia Kovalskaya et al. PROTEIN EXPRESSION AND PURIFICATION
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