De novo production of the plant-derived alkaloid strictosidine in yeast

Terpenoid Biosynthesis Off the Beaten Track: Unconventional Cyclases and Their Impact on Biomimetic Synthesis

(2014) Martin Baunach et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Conversion of Substrate Analogs Suggests a Michael Cyclization in Iridoid Biosynthesis

(2014) Stephanie Lindner et al.   CHEMISTRY & BIOLOGY

A look inside an alkaloid multisite plant: the Catharanthus logistics

(2014) Vincent Courdavault et al.   CURRENT OPINION IN PLANT BIOLOGY

Making iridoids/secoiridoids and monoterpenoid indole alkaloids: progress on pathway elucidation

(2014) Vincenzo De Luca et al.   CURRENT OPINION IN PLANT BIOLOGY

A microbial biomanufacturing platform for natural and semisynthetic opioids

(2014) Kate Thodey et al.   Nature Chemical Biology

7-Deoxyloganetic acid synthase catalyzes a key 3 step oxidation to form 7-deoxyloganetic acid in Catharanthus roseus iridoid biosynthesis

(2014) Vonny Salim et al.   PHYTOCHEMISTRY

Combinatorial biosynthesis of sapogenins and saponins in Saccharomyces cerevisiae using a C-16  hydroxylase from Bupleurum falcatum

(2014) T. Moses et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstitution of a 10-gene pathway for synthesis of the plant alkaloid dihydrosanguinarine in Saccharomyces cerevisiae

(2014) Elena Fossati et al.   Nature Communications

(R,S)-Tetrahydropapaveroline production by stepwise fermentation using engineered Escherichia coli

(2014) Akira Nakagawa et al.   Scientific Reports

Overproduction of geraniol by enhanced precursor supply in Saccharomyces cerevisiae

(2013) Jidong Liu et al.   JOURNAL OF BIOTECHNOLOGY

Metabolic engineering of Saccharomyces cerevisiae for production of ginsenosides

(2013) Zhubo Dai et al.   METABOLIC ENGINEERING

2,2-Diphenyl-1-picrylhydrazyl as a screening tool for recombinant monoterpene biosynthesis

(2013) James BYH Behrendorff et al.   Microbial Cell Factories

High-level semi-synthetic production of the potent antimalarial artemisinin

(2013) C. J. Paddon et al.   NATURE

Engineering Monoterpene Production in Yeast Using a Synthetic Dominant Negative Geranyl Diphosphate Synthase

(2013) Codruta Ignea et al.   ACS Synthetic Biology

Progress in the research of S-adenosyl-l-methionine production

(2012) Ju Chu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Genetic analysis of geraniol metabolism during fermentation

(2012) Damien Steyer et al.   FOOD MICROBIOLOGY

A Remarkable Series of Vinblastine Analogues Displaying Enhanced Activity and an Unprecedented Tubulin Binding Steric Tolerance: C20′ Urea Derivatives

(2012) Erick K. Leggans et al.   JOURNAL OF MEDICINAL CHEMISTRY

Modular Pathway Engineering of Diterpenoid Synthases and the Mevalonic Acid Pathway for Miltiradiene Production

(2012) Yongjin J. Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An alternative route to cyclic terpenes by reductive cyclization in iridoid biosynthesis

(2012) Fernando Geu-Flores et al.   NATURE

Metabolic engineering of monoterpene synthesis in yeast

(2011) Marc J. C. Fischer et al.   BIOTECHNOLOGY AND BIOENGINEERING

Introduction and expression of genes for metabolic engineering applications in Saccharomyces cerevisiae

(2011) Nancy A. Da Silva et al.   FEMS YEAST RESEARCH

Optimization of a heterologous pathway for the production of flavonoids from glucose

(2011) Christine Nicole S. Santos et al.   METABOLIC ENGINEERING

Improving yeast strains using recyclable integration cassettes, for the production of plant terpenoids

(2011) Codruta Ignea et al.   Microbial Cell Factories

Development of Non-Natural Flavanones as Antimicrobial Agents

(2011) Zachary L. Fowler et al.   PLoS One

Metabolic Engineering for the Production of Natural Products

(2011) Lauren B. Pickens et al.   Annual Review of Chemical and Biomolecular Engineering

Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli

(2010) P. K. Ajikumar et al.   SCIENCE

A vector set for systematic metabolic engineering in Saccharomyces cerevisiae

(2010) Fang Fang et al.   YEAST

Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae

(2008) Kristy M Hawkins et al.   Nature Chemical Biology

Microbial production of plant benzylisoquinoline alkaloids

(2008) H. Minami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Coupling of Catharanthine and Vindoline to Provide Vinblastine:  Total Synthesis of (+)- andent-(−)-Vinblastine

(2007) Hayato Ishikawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY