Bioinspired iterative synthesis of polyketides

α-Hydroxyallylsilanes as Propionaldehyde Enolate Equivalents and Their Use toward Iterative Aldol Reactions

(2015) Johal Ruiz et al.   JOURNAL OF ORGANIC CHEMISTRY

Toward Ideality: The Synthesis of (+)-Kalkitoxin and (+)-Hydroxyphthioceranic Acid by Assembly-Line Synthesis

(2015) Sebastien Balieu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of many different types of organic small molecules using one automated process

(2015) J. Li et al.   SCIENCE

Lithiation–Borylation Methodology and Its Application in Synthesis

(2014) Daniele Leonori et al.   ACCOUNTS OF CHEMICAL RESEARCH

Accelerating Spirocyclic Polyketide Synthesis using Flow Chemistry

(2014) Sean Newton et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereocontrolled Synthesis of Adjacent Acyclic Quaternary-Tertiary Motifs: Application to a Concise Total Synthesis of (−)-Filiformin

(2014) Daniel J. Blair et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Assembly-line synthesis of organic molecules with tailored shapes

(2014) Matthew Burns et al.   NATURE

Structure of a modular polyketide synthase

(2014) Somnath Dutta et al.   NATURE

Structural rearrangements of a polyketide synthase module during its catalytic cycle

(2014) Jonathan R. Whicher et al.   NATURE

Synthesis of most polyene natural product motifs using just 12 building blocks and one coupling reaction

(2014) Eric M. Woerly et al.   Nature Chemistry

Synthesis of hydroxyphthioceranic acid using a traceless lithiation–borylation–protodeboronation strategy

(2014) Ramesh Rasappan et al.   Nature Chemistry

Iterative Direct Aldol Strategy for Polypropionates: Enantioselective Total Synthesis of (−)-Membrenone A and B

(2014) Kaliyamoorthy Alagiri et al.   ORGANIC LETTERS

Iterative Iodocyclization: Total Synthesis of Polyrhacitide B

(2014) Debendra Mohapatra et al.   SYNTHESIS-STUTTGART

Boronic Esters in Asymmetric Synthesis

(2013) Donald S. Matteson   JOURNAL OF ORGANIC CHEMISTRY

Diastereoselective Construction of syn-1,3-Dioxanes via a Bismuth-Mediated Two-Component Hemiacetal/Oxa-Conjugate Addition Reaction

(2012) P. Andrew Evans et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An iterative Shimizu non-aldol approach for the stereoselective synthesis of C13-C22 fragment of callystatin A

(2012) Sandip A. Pujari et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Total synthesis, stereochemical elucidation and biological evaluation of Ac2SGL; a 1,3-methyl branched sulfoglycolipid from Mycobacterium tuberculosis

(2012) Danny Geerdink et al.   Chemical Science

Integrated Synthetic Strategy for Higher Catechin Oligomers

(2011) Ken Ohmori et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rapid Total Syntheses Utilizing “Supersilyl” Chemistry

(2011) Brian J. Albert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The thiopyran route to polypropionates

(2011) Dale E. Ward   CHEMICAL COMMUNICATIONS

Organocatalytic stereoselective synthesis of passifloricin A

(2011) Pradeep Kumar et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A Simple and General Platform for Generating Stereochemically Complex Polyene Frameworks by Iterative Cross-Coupling

(2010) Suk Joong Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Triple-Aldol Cascade Reaction for the Rapid Assembly of Polyketides

(2010) Brian J. Albert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iterative strategies for the synthesis of deoxypropionates

(2010) Bjorn ter Horst et al.   CHEMICAL COMMUNICATIONS

Total Synthesis of (+)-Roxaticin via C−C Bond Forming Transfer Hydrogenation: A Departure from Stoichiometric Chiral Reagents, Auxiliaries, and Premetalated Nucleophiles in Polyketide Construction

(2010) Soo Bong Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Controlled Iterative Cross-Coupling: On the Way to the Automation of Organic Synthesis

(2009) Congyang Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Total Synthesis of (−)-Pironetin: Iterative Aldol Reactions of Thiazolidinethiones

(2009) Michael T. Crimmins et al.   ORGANIC LETTERS

Total Synthesis of Polyrhacitides A and B by Use of an Iterative Strategy for the Stereoselective Synthesis of 1,3-Polyol Arrays

(2009) Helge Menz et al.   ORGANIC LETTERS

Enantioselective Iridium-Catalyzed Carbonyl Allylation from the Alcohol or Aldehyde Oxidation Level Using Allyl Acetate as an Allyl Metal Surrogate

(2008) In Su Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iterative Cr-Mediated Catalytic Asymmetric Allylation To Synthesizesyn/syn- andanti/anti-1,3,5-Triols

(2008) Zhiyu Zhang et al.   ORGANIC LETTERS